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Volumn 127, Issue 26, 2016, Pages 3387-3397

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BRCA2 PROTEIN; DNA; DNA METHYLTRANSFERASE 3A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE 3; PANCRELIPASE; PROTEIN P53; STAT3 PROTEIN; STAT5B PROTEIN; T LYMPHOCYTE RECEPTOR; TUMOR PROTEIN;

EID: 85015430118     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-02-699843     Document Type: Article
Times cited : (89)

References (88)
  • 1
    • 78149236112 scopus 로고    scopus 로고
    • Survival outcomes and prognostic factors in mycosis fungoides/Sézary syndrome: Validation of the revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer staging proposal
    • Agar NS, Wedgeworth E, Crichton S, et al. Survival outcomes and prognostic factors in mycosis fungoides/Sézary syndrome: validation of the revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer staging proposal. J Clin Oncol. 2010;28(31):4730-4739.
    • (2010) J Clin Oncol. , vol.28 , Issue.31 , pp. 4730-4739
    • Agar, N.S.1    Wedgeworth, E.2    Crichton, S.3
  • 2
    • 20844443468 scopus 로고    scopus 로고
    • WHO-EORTC classification for cutaneous lymphomas
    • Willemze R, Jaffe ES, Burg G, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105(10):3768-3785.
    • (2005) Blood , vol.105 , Issue.10 , pp. 3768-3785
    • Willemze, R.1    Jaffe, E.S.2    Burg, G.3
  • 3
    • 84940585634 scopus 로고    scopus 로고
    • Genomic landscape of cutaneous T cell lymphoma
    • Choi J, Goh G, Walradt T, et al. Genomic landscape of cutaneous T cell lymphoma. Nat Genet. 2015;47(9):1011-1019.
    • (2015) Nat Genet. , vol.47 , Issue.9 , pp. 1011-1019
    • Choi, J.1    Goh, G.2    Walradt, T.3
  • 4
    • 84949096789 scopus 로고    scopus 로고
    • Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes
    • Wang L, Ni X, Covington KR, et al. Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes. Nat Genet. 2015;47(12):1426-1434.
    • (2015) Nat Genet. , vol.47 , Issue.12 , pp. 1426-1434
    • Wang, L.1    Ni, X.2    Covington, K.R.3
  • 5
    • 84940607197 scopus 로고    scopus 로고
    • Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2
    • Ungewickell A, Bhaduri A, Rios E, et al. Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2. Nat Genet. 2015;47(9):1056-1060.
    • (2015) Nat Genet. , vol.47 , Issue.9 , pp. 1056-1060
    • Ungewickell, A.1    Bhaduri, A.2    Rios, E.3
  • 6
    • 84897520067 scopus 로고    scopus 로고
    • PLCG1 mutations in cutaneous T-cell lymphomas
    • Vaqué JP, Gómez-López G, Monsálvez V, et al. PLCG1 mutations in cutaneous T-cell lymphomas. Blood. 2014;123(13):2034-2043.
    • (2014) Blood , vol.123 , Issue.13 , pp. 2034-2043
    • Vaqué, J.P.1    Gómez-López, G.2    Monsálvez, V.3
  • 7
    • 84949107950 scopus 로고    scopus 로고
    • The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome
    • da Silva Almeida AC, Abate F, Khiabanian H, et al. The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome. Nat Genet. 2015;47(12):1465-1470.
    • (2015) Nat Genet. , vol.47 , Issue.12 , pp. 1465-1470
    • Da Silva Almeida, A.C.1    Abate, F.2    Khiabanian, H.3
  • 8
    • 84942771332 scopus 로고    scopus 로고
    • Genomic analyses reveal recurrent mutations in epigenetic modifiers and the JAK-STAT pathway in Sézary syndrome
    • Kiel MJ, Sahasrabuddhe AA, Rolland DC, et al. Genomic analyses reveal recurrent mutations in epigenetic modifiers and the JAK-STAT pathway in Sézary syndrome. Nat Commun. 2015;6(8470):8470.
    • (2015) Nat Commun. , vol.6 , Issue.8470 , pp. 8470
    • Kiel, M.J.1    Sahasrabuddhe, A.A.2    Rolland, D.C.3
  • 9
    • 84937931145 scopus 로고    scopus 로고
    • Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides
    • McGirt LY, Jia P, Baerenwald DA, et al. Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides. Blood. 2015;126(4):508-519.
    • (2015) Blood , vol.126 , Issue.4 , pp. 508-519
    • McGirt, L.Y.1    Jia, P.2    Baerenwald, D.A.3
  • 10
    • 84923076524 scopus 로고    scopus 로고
    • Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells
    • Küçük C, Jiang B, Hu X, et al. Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells. Nat Commun. 2015;6:6025.
    • (2015) Nat Commun. , vol.6 , pp. 6025
    • Küçük, C.1    Jiang, B.2    Hu, X.3
  • 11
    • 84901790926 scopus 로고    scopus 로고
    • Disease-specific mutations in mature lymphoid neoplasms: Recent advances
    • Sakata-Yanagimoto M, Enami T, Yokoyama Y, Chiba S. Disease-specific mutations in mature lymphoid neoplasms: recent advances. Cancer Sci. 2014;105(6):623-629.
    • (2014) Cancer Sci. , vol.105 , Issue.6 , pp. 623-629
    • Sakata-Yanagimoto, M.1    Enami, T.2    Yokoyama, Y.3    Chiba, S.4
  • 12
    • 84895829862 scopus 로고    scopus 로고
    • Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas
    • Palomero T, Couronné L, Khiabanian H, et al. Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas. Nat Genet. 2014;46(2):166-170.
    • (2014) Nat Genet. , vol.46 , Issue.2 , pp. 166-170
    • Palomero, T.1    Couronné, L.2    Khiabanian, H.3
  • 13
    • 84945344219 scopus 로고    scopus 로고
    • Integrated molecular analysis of adult T cell leukemia/lymphoma
    • Kataoka K, Nagata Y, Kitanaka A, et al. Integrated molecular analysis of adult T cell leukemia/lymphoma. Nat Genet. 2015;47(11):1304-1315.
    • (2015) Nat Genet. , vol.47 , Issue.11 , pp. 1304-1315
    • Kataoka, K.1    Nagata, Y.2    Kitanaka, A.3
  • 14
    • 77956534324 scopus 로고    scopus 로고
    • ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
    • Wang K, Li M, Hakonarson H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 2010;38(16):e164.
    • (2010) Nucleic Acids Res. , vol.38 , Issue.16 , pp. e164
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 15
    • 84858296342 scopus 로고    scopus 로고
    • Detecting false-positive signals in exome sequencing
    • NISC Comparative Sequencing Program
    • Fuentes Fajardo KV, Adams D, Mason CE, et al; NISC Comparative Sequencing Program. Detecting false-positive signals in exome sequencing. Hum Mutat. 2012;33(4):609-613.
    • (2012) Hum Mutat , vol.33 , Issue.4 , pp. 609-613
    • Fuentes Fajardo, K.V.1    Adams, D.2    Mason, C.E.3
  • 16
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence MS, Stojanov P, Polak P, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013;499(7457):214-218.
    • (2013) Nature , vol.499 , Issue.7457 , pp. 214-218
    • Lawrence, M.S.1    Stojanov, P.2    Polak, P.3
  • 18
    • 84976893968 scopus 로고    scopus 로고
    • NCG 5.0: Updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings
    • An O, Dall'Olio GM, Mourikis TP, Ciccarelli FD. NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings. Nucleic Acids Res. 2016;44(D1):D992-D999.
    • (2016) Nucleic Acids Res. , vol.44 , Issue.D1 , pp. D992-D999
    • An, O.1    Dall'Olio, G.M.2    Mourikis, T.P.3    Ciccarelli, F.D.4
  • 19
    • 84868026566 scopus 로고    scopus 로고
    • A robust model for read count data in exome sequencing experiments and implications for copy number variant calling
    • Plagnol V, Curtis J, Epstein M, et al. A robust model for read count data in exome sequencing experiments and implications for copy number variant calling. Bioinformatics. 2012;28(21):2747-2754.
    • (2012) Bioinformatics , vol.28 , Issue.21 , pp. 2747-2754
    • Plagnol, V.1    Curtis, J.2    Epstein, M.3
  • 20
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Australian Pancreatic Cancer Genome Initiative; ICGC PedBrain
    • Alexandrov LB, Nik-Zainal S, Wedge DC, et al; Australian Pancreatic Cancer Genome Initiative; ICGC Breast Cancer Consortium; ICGC MMML-Seq Consortium; ICGC PedBrain. Signatures of mutational processes in human cancer. Nature. 2013;500(7463):415-421.
    • (2013) Nature , vol.500 , Issue.7463 , pp. 415-421
    • Alexandrov, L.B.1    Nik-Zainal, S.2    Wedge, D.C.3
  • 21
    • 0036047949 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of cutaneous T-cell lymphomas: Identification of common genetic alterations in Sézary syndrome and mycosis fungoides
    • Mao X, Lillington D, Scarisbrick JJ, et al. Molecular cytogenetic analysis of cutaneous T-cell lymphomas: identification of common genetic alterations in Sézary syndrome and mycosis fungoides. Br J Dermatol. 2002;147(3):464-475.
    • (2002) Br J Dermatol. , vol.147 , Issue.3 , pp. 464-475
    • Mao, X.1    Lillington, D.2    Scarisbrick, J.J.3
  • 22
    • 70350542803 scopus 로고    scopus 로고
    • Identification of key regions and genes important in the pathogenesis of sezary syndrome by combining genomic and expression microarrays
    • Caprini E, Cristofoletti C, Arcelli D, et al. Identification of key regions and genes important in the pathogenesis of sezary syndrome by combining genomic and expression microarrays. Cancer Res. 2009;69(21):8438-8446.
    • (2009) Cancer Res. , vol.69 , Issue.21 , pp. 8438-8446
    • Caprini, E.1    Cristofoletti, C.2    Arcelli, D.3
  • 23
    • 77949521627 scopus 로고    scopus 로고
    • Oligonucleotide array-CGH identifies genomic subgroups and prognostic markers for tumor stage mycosis fungoides
    • Salgado R, Servitje O, Gallardo F, et al. Oligonucleotide array-CGH identifies genomic subgroups and prognostic markers for tumor stage mycosis fungoides. J Invest Dermatol. 2010;130(4):1126-1135.
    • (2010) J Invest Dermatol. , vol.130 , Issue.4 , pp. 1126-1135
    • Salgado, R.1    Servitje, O.2    Gallardo, F.3
  • 24
    • 79955054456 scopus 로고    scopus 로고
    • Genetic alterations in Sezary syndrome
    • Iżykowska K, Przybylski GK. Genetic alterations in Sezary syndrome. Leuk Lymphoma. 2011;52(5):745-753.
    • (2011) Leuk Lymphoma , vol.52 , Issue.5 , pp. 745-753
    • Izykowska, K.1    Przybylski, G.K.2
  • 25
    • 57149107372 scopus 로고    scopus 로고
    • Array-based comparative genomic hybridization in early-stage mycosis fungoides: Recurrent deletion of tumor suppressor genes BCL7A, SMAC/DIABLO, and RHOF
    • Carbone A, Bernardini L, Valenzano F, et al. Array-based comparative genomic hybridization in early-stage mycosis fungoides: recurrent deletion of tumor suppressor genes BCL7A, SMAC/DIABLO, and RHOF. Genes Chromosomes Cancer. 2008;47(12):1067-1075.
    • (2008) Genes Chromosomes Cancer , vol.47 , Issue.12 , pp. 1067-1075
    • Carbone, A.1    Bernardini, L.2    Valenzano, F.3
  • 26
    • 0024268765 scopus 로고
    • Cytogenetics of T-cell malignant lymphoma. Report of 17 cases and review of the chromosomal breakpoints
    • Berger R, Baranger L, Bernheim A, Valensi F, Flandrin G. Cytogenetics of T-cell malignant lymphoma. Report of 17 cases and review of the chromosomal breakpoints. Cancer Genet Cytogenet. 1988;36(1):123-130.
    • (1988) Cancer Genet Cytogenet. , vol.36 , Issue.1 , pp. 123-130
    • Berger, R.1    Baranger, L.2    Bernheim, A.3    Valensi, F.4    Flandrin, G.5
  • 27
    • 0020043346 scopus 로고
    • Clonal characteristics of cutaneous T cell lymphomas: Cytogenetic evidence from blood, lymph nodes, and skin
    • Nowell PC, Finan JB, Vonderheid EC. Clonal characteristics of cutaneous T cell lymphomas: cytogenetic evidence from blood, lymph nodes, and skin. J Invest Dermatol. 1982;78(1):69-75.
    • (1982) J Invest Dermatol. , vol.78 , Issue.1 , pp. 69-75
    • Nowell, P.C.1    Finan, J.B.2    Vonderheid, E.C.3
  • 28
    • 0030904865 scopus 로고    scopus 로고
    • Recurring structural chromosome abnormalities in peripheral blood lymphocytes of patients with mycosis fungoides/Sézary syndrome
    • Thangavelu M, Finn WG, Yelavarthi KK, et al. Recurring structural chromosome abnormalities in peripheral blood lymphocytes of patients with mycosis fungoides/Sézary syndrome. Blood. 1997;89(9):3371-3377.
    • (1997) Blood , vol.89 , Issue.9 , pp. 3371-3377
    • Thangavelu, M.1    Finn, W.G.2    Yelavarthi, K.K.3
  • 29
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature. 2013;502(7471):333-339.
    • (2013) Nature , vol.502 , Issue.7471 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3
  • 30
    • 84865168855 scopus 로고    scopus 로고
    • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing
    • Liu P, Morrison C, Wang L, et al. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis. 2012;33(7):1270-1276.
    • (2012) Carcinogenesis , vol.33 , Issue.7 , pp. 1270-1276
    • Liu, P.1    Morrison, C.2    Wang, L.3
  • 31
    • 84869854258 scopus 로고    scopus 로고
    • Function and cancer genomics of FAT family genes
    • review
    • Katoh M. Function and cancer genomics of FAT family genes (review). Int J Oncol. 2012;41(6):1913-1918.
    • (2012) Int J Oncol. , vol.41 , Issue.6 , pp. 1913-1918
    • Katoh, M.1
  • 32
    • 84910020229 scopus 로고    scopus 로고
    • A recurrent activating PLCG1 mutation in cardiac angiosarcomas increases apoptosis resistance and invasiveness of endothelial cells
    • Kunze K, Spieker T, Gamerdinger U, et al. A recurrent activating PLCG1 mutation in cardiac angiosarcomas increases apoptosis resistance and invasiveness of endothelial cells. Cancer Res. 2014;74(21):6173-6183.
    • (2014) Cancer Res. , vol.74 , Issue.21 , pp. 6173-6183
    • Kunze, K.1    Spieker, T.2    Gamerdinger, U.3
  • 33
    • 33846250804 scopus 로고    scopus 로고
    • Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors
    • Natrajan R, Little SE, Reis-Filho JS, et al. Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors. Clin Cancer Res. 2006;12(24):7284-7293.
    • (2006) Clin Cancer Res. , vol.12 , Issue.24 , pp. 7284-7293
    • Natrajan, R.1    Little, S.E.2    Reis-Filho, J.S.3
  • 34
    • 84862536510 scopus 로고    scopus 로고
    • Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways
    • Tassi E, Zanon M, Vegetti C, et al. Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways. Clin Cancer Res. 2012;18(12):3316-3327.
    • (2012) Clin Cancer Res. , vol.18 , Issue.12 , pp. 3316-3327
    • Tassi, E.1    Zanon, M.2    Vegetti, C.3
  • 35
    • 84942645585 scopus 로고    scopus 로고
    • A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families
    • Calvete O, Martinez P, Garcia-Pavia P, et al. A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families. Nat Commun. 2015;6(8383):8383.
    • (2015) Nat Commun. , vol.6 , Issue.8383 , pp. 8383
    • Calvete, O.1    Martinez, P.2    Garcia-Pavia, P.3
  • 36
    • 84920200929 scopus 로고    scopus 로고
    • Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomas
    • Manso R, Rodríguez-Pinilla SM, González-Rincón J, et al. Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomas. Haematologica. 2015;100(1):e25-e27.
    • (2015) Haematologica , vol.100 , Issue.1 , pp. e25-e27
    • Manso, R.1    Rodríguez-Pinilla, S.M.2    González-Rincón, J.3
  • 37
    • 84939465614 scopus 로고    scopus 로고
    • PLCG1 Gene Mutations Are Uncommon in Cutaneous T-Cell Lymphomas
    • Caumont C, Gros A, Boucher C, et al. PLCG1 Gene Mutations Are Uncommon in Cutaneous T-Cell Lymphomas. J Invest Dermatol. 2015;135(9):2334-2337.
    • (2015) J Invest Dermatol. , vol.135 , Issue.9 , pp. 2334-2337
    • Caumont, C.1    Gros, A.2    Boucher, C.3
  • 38
    • 69249083630 scopus 로고    scopus 로고
    • Characterization of phospholipase C gamma enzymes with gain-of-function mutations
    • Everett KL, Bunney TD, Yoon Y, et al. Characterization of phospholipase C gamma enzymes with gain-of-function mutations. J Biol Chem. 2009;284(34):23083-23093.
    • (2009) J Biol Chem. , vol.284 , Issue.34 , pp. 23083-23093
    • Everett, K.L.1    Bunney, T.D.2    Yoon, Y.3
  • 39
    • 84923256369 scopus 로고    scopus 로고
    • Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes
    • Dhanasekaran SM, Balbin OA, Chen G, et al. Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes. Nat Commun. 2014;5(5893):5893.
    • (2014) Nat Commun. , vol.5 , Issue.5893 , pp. 5893
    • Dhanasekaran, S.M.1    Balbin, O.A.2    Chen, G.3
  • 40
    • 84911909502 scopus 로고    scopus 로고
    • JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model
    • Degryse S, de Bock CE, Cox L, et al. JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model. Blood. 2014;124(20):3092-3100.
    • (2014) Blood , vol.124 , Issue.20 , pp. 3092-3100
    • Degryse, S.1    De Bock, C.E.2    Cox, L.3
  • 41
    • 84866314162 scopus 로고    scopus 로고
    • Janus kinase 3-activating mutations identified in natural killer/T-cell lymphoma
    • Koo GC, Tan SY, Tang T, et al. Janus kinase 3-activating mutations identified in natural killer/T-cell lymphoma. Cancer Discov. 2012;2(7):591-597.
    • (2012) Cancer Discov , vol.2 , Issue.7 , pp. 591-597
    • Koo, G.C.1    Tan, S.Y.2    Tang, T.3
  • 42
    • 84861023172 scopus 로고    scopus 로고
    • Somatic STAT3 mutations in large granular lymphocytic leukemia
    • Koskela HL, Eldfors S, Ellonen P, et al. Somatic STAT3 mutations in large granular lymphocytic leukemia. N Engl J Med. 2012;366(20):1905-1913.
    • (2012) N Engl J Med. , vol.366 , Issue.20 , pp. 1905-1913
    • Koskela, H.L.1    Eldfors, S.2    Ellonen, P.3
  • 43
    • 84905675937 scopus 로고    scopus 로고
    • Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia
    • Kontro M, Kuusanmäki H, Eldfors S, et al. Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia. Leukemia. 2014;28(8):1738-1742.
    • (2014) Leukemia , vol.28 , Issue.8 , pp. 1738-1742
    • Kontro, M.1    Kuusanmäki, H.2    Eldfors, S.3
  • 44
    • 84880768462 scopus 로고    scopus 로고
    • Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
    • Rajala HL, Eldfors S, Kuusanmäki H, et al. Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia. Blood. 2013;121(22):4541-4550.
    • (2013) Blood , vol.121 , Issue.22 , pp. 4541-4550
    • Rajala, H.L.1    Eldfors, S.2    Kuusanmäki, H.3
  • 45
    • 84907524562 scopus 로고    scopus 로고
    • The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse
    • Bandapalli OR, Schuessele S, Kunz JB, et al. The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse. Haematologica. 2014;99(10):e188-e192.
    • (2014) Haematologica , vol.99 , Issue.10 , pp. e188-e192
    • Bandapalli, O.R.1    Schuessele, S.2    Kunz, J.B.3
  • 46
    • 18744427797 scopus 로고    scopus 로고
    • Constitutively active STAT5A and STAT5B in vitro and in vivo: Mutation of STAT5 is not a frequent cause of leukemogenesis
    • Yamada K, Ariyoshi K, Onishi M, et al. Constitutively active STAT5A and STAT5B in vitro and in vivo: mutation of STAT5 is not a frequent cause of leukemogenesis. Int J Hematol. 2000;71(1):46-54.
    • (2000) Int J Hematol. , vol.71 , Issue.1 , pp. 46-54
    • Yamada, K.1    Ariyoshi, K.2    Onishi, M.3
  • 47
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674.
    • (2011) Cell. , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 48
    • 84886882646 scopus 로고    scopus 로고
    • Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome
    • Nikolaev SI, Santoni F, Vannier A, et al. Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome. Blood. 2013;122(4):554-561.
    • (2013) Blood , vol.122 , Issue.4 , pp. 554-561
    • Nikolaev, S.I.1    Santoni, F.2    Vannier, A.3
  • 49
    • 74449085934 scopus 로고    scopus 로고
    • A small-cell lung cancer genome with complex signatures of tobacco exposure
    • Pleasance ED, Stephens PJ, O'Meara S, et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature. 2010;463(7278):184-190.
    • (2010) Nature , vol.463 , Issue.7278 , pp. 184-190
    • Pleasance, E.D.1    Stephens, P.J.2    O'Meara, S.3
  • 50
    • 84863393606 scopus 로고    scopus 로고
    • Whole genome sequencing of matched primary and metastatic acral melanomas
    • Turajlic S, Furney SJ, Lambros MB, et al. Whole genome sequencing of matched primary and metastatic acral melanomas. Genome Res. 2012;22(2):196-207.
    • (2012) Genome Res. , vol.22 , Issue.2 , pp. 196-207
    • Turajlic, S.1    Furney, S.J.2    Lambros, M.B.3
  • 51
    • 84924666501 scopus 로고    scopus 로고
    • Targeted next-generation sequencing in chronic lymphocytic leukemia: A high-throughput yet tailored approach will facilitate implementation in a clinical setting
    • Sutton LA, Ljungström V, Mansouri L, et al. Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting. Haematologica. 2015;100(3):370-376.
    • (2015) Haematologica , vol.100 , Issue.3 , pp. 370-376
    • Sutton, L.A.1    Ljungström, V.2    Mansouri, L.3
  • 52
    • 84924630391 scopus 로고    scopus 로고
    • The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing
    • Vater I, Montesinos-Rongen M, Schlesner M, et al. The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing. Leukemia. 2015;29(3):677-685.
    • (2015) Leukemia , vol.29 , Issue.3 , pp. 677-685
    • Vater, I.1    Montesinos-Rongen, M.2    Schlesner, M.3
  • 53
    • 84930003179 scopus 로고    scopus 로고
    • Age-related mutations associated with clonal hematopoietic expansion and malignancies
    • Xie M, Lu C, Wang J, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med. 2014;20(12):1472-1478.
    • (2014) Nat Med. , vol.20 , Issue.12 , pp. 1472-1478
    • Xie, M.1    Lu, C.2    Wang, J.3
  • 54
    • 84899624984 scopus 로고    scopus 로고
    • POT1 loss-of-function variants predispose to familial melanoma
    • Robles-Espinoza CD, Harland M, Ramsay AJ, et al. POT1 loss-of-function variants predispose to familial melanoma. Nat Genet. 2014;46(5):478-481.
    • (2014) Nat Genet. , vol.46 , Issue.5 , pp. 478-481
    • Robles-Espinoza, C.D.1    Harland, M.2    Ramsay, A.J.3
  • 55
    • 0038451396 scopus 로고    scopus 로고
    • POT1 as a terminal transducer of TRF1 telomere length control
    • Loayza D, De Lange T. POT1 as a terminal transducer of TRF1 telomere length control. Nature. 2003;423(6943):1013-1018.
    • (2003) Nature , vol.423 , Issue.6943 , pp. 1013-1018
    • Loayza, D.1    De Lange, T.2
  • 56
    • 33749369156 scopus 로고    scopus 로고
    • Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication
    • Lazzerini Denchi E, Celli G, de Lange T. Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication. Genes Dev. 2006;20(19):2648-2653.
    • (2006) Genes Dev. , vol.20 , Issue.19 , pp. 2648-2653
    • Lazzerini Denchi, E.1    Celli, G.2    De Lange, T.3
  • 57
    • 84878551940 scopus 로고    scopus 로고
    • POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
    • Ramsay AJ, Quesada V, Foronda M, et al. POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia. Nat Genet. 2013;45(5):526-530.
    • (2013) Nat Genet. , vol.45 , Issue.5 , pp. 526-530
    • Ramsay, A.J.1    Quesada, V.2    Foronda, M.3
  • 58
    • 84878527709 scopus 로고    scopus 로고
    • Pathogenesis of ataxiatelangiectasia: The next generation of ATM functions
    • Ambrose M, Gatti RA. Pathogenesis of ataxiatelangiectasia: the next generation of ATM functions. Blood. 2013;121(20):4036-4045.
    • (2013) Blood , vol.121 , Issue.20 , pp. 4036-4045
    • Ambrose, M.1    Gatti, R.A.2
  • 59
    • 84902330508 scopus 로고    scopus 로고
    • New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis
    • Valle L, Hernández-Illán E, Bellido F, et al. New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis. Hum Mol Genet. 2014;23(13):3506-3512.
    • (2014) Hum Mol Genet. , vol.23 , Issue.13 , pp. 3506-3512
    • Valle, L.1    Hernández-Illán, E.2    Bellido, F.3
  • 60
    • 0032825123 scopus 로고    scopus 로고
    • McBurney E. P53 tumor suppressor gene mutations in transformed cutaneous T-cell lymphoma: A study of 12 cases
    • Marrogi AJ, Khan MA, Vonderheid EC, Wood GS, McBurney E. p53 tumor suppressor gene mutations in transformed cutaneous T-cell lymphoma: a study of 12 cases. J Cutan Pathol. 1999;26(8):369-378.
    • (1999) J Cutan Pathol. , vol.26 , Issue.8 , pp. 369-378
    • Marrogi, A.J.1    Khan, M.A.2    Vonderheid, E.C.3    Wood, G.S.4
  • 61
    • 0033052124 scopus 로고    scopus 로고
    • Spectrum of p53 gene mutations suggests a possible role for ultraviolet radiation in the pathogenesis of advanced cutaneous lymphomas
    • McGregor JM, Crook T, Fraser-Andrews EA, et al. Spectrum of p53 gene mutations suggests a possible role for ultraviolet radiation in the pathogenesis of advanced cutaneous lymphomas. J Invest Dermatol. 1999;112(3):317-321.
    • (1999) J Invest Dermatol. , vol.112 , Issue.3 , pp. 317-321
    • McGregor, J.M.1    Crook, T.2    Fraser-Andrews, E.A.3
  • 62
    • 2942538551 scopus 로고    scopus 로고
    • Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice
    • Canela A, Martín-Caballero J, Flores JM, Blasco MA. Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice. Mol Cell Biol. 2004;24(10):4275-4293.
    • (2004) Mol Cell Biol. , vol.24 , Issue.10 , pp. 4275-4293
    • Canela, A.1    Martín-Caballero, J.2    Flores, J.M.3    Blasco, M.A.4
  • 63
    • 84918820723 scopus 로고    scopus 로고
    • Dysfunction of phospholipase Cγ in immune disorders and cancer
    • Koss H, Bunney TD, Behjati S, Katan M. Dysfunction of phospholipase Cγ in immune disorders and cancer. Trends Biochem Sci. 2014;39(12):603-611.
    • (2014) Trends Biochem Sci. , vol.39 , Issue.12 , pp. 603-611
    • Koss, H.1    Bunney, T.D.2    Behjati, S.3    Katan, M.4
  • 64
    • 33644755512 scopus 로고    scopus 로고
    • Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis
    • Sors A, Jean-Louis F, Pellet C, et al. Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis. Blood. 2006;107(6):2354-2363.
    • (2006) Blood , vol.107 , Issue.6 , pp. 2354-2363
    • Sors, A.1    Jean-Louis, F.2    Pellet, C.3
  • 65
    • 0034518556 scopus 로고    scopus 로고
    • Constitutive expression of NF-kappa B is a characteristic feature of mycosis fungoides: Implications for apoptosis resistance and pathogenesis
    • Izban KF, Ergin M, Qin JZ, et al. Constitutive expression of NF-kappa B is a characteristic feature of mycosis fungoides: implications for apoptosis resistance and pathogenesis. Hum Pathol. 2000;31(12):1482-1490.
    • (2000) Hum Pathol. , vol.31 , Issue.12 , pp. 1482-1490
    • Izban, K.F.1    Ergin, M.2    Qin, J.Z.3
  • 66
    • 77952295698 scopus 로고    scopus 로고
    • The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma
    • Pechloff K, Holch J, Ferch U, et al. The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma. J Exp Med. 2010;207(5):1031-1044.
    • (2010) J Exp Med. , vol.207 , Issue.5 , pp. 1031-1044
    • Pechloff, K.1    Holch, J.2    Ferch, U.3
  • 67
    • 0028353897 scopus 로고
    • Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia
    • Wright DD, Sefton BM, Kamps MP. Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia. Mol Cell Biol. 1994;14(4):2429-2437.
    • (1994) Mol Cell Biol. , vol.14 , Issue.4 , pp. 2429-2437
    • Wright, D.D.1    Sefton, B.M.2    Kamps, M.P.3
  • 68
    • 65249094257 scopus 로고    scopus 로고
    • Targeting apoptosis defects in cutaneous T-cell lymphoma
    • Contassot E, French LE. Targeting apoptosis defects in cutaneous T-cell lymphoma. J Invest Dermatol. 2009;129(5):1059-1061.
    • (2009) J Invest Dermatol. , vol.129 , Issue.5 , pp. 1059-1061
    • Contassot, E.1    French, L.E.2
  • 69
    • 65249125807 scopus 로고    scopus 로고
    • Low FAS/CD95 expression by CTCL correlates with reduced sensitivity to apoptosis that can be restored by FAS upregulation
    • Wu J, Nihal M, Siddiqui J, Vonderheid EC, Wood GS. Low FAS/CD95 expression by CTCL correlates with reduced sensitivity to apoptosis that can be restored by FAS upregulation. J Invest Dermatol. 2009;129(5):1165-1173.
    • (2009) J Invest Dermatol. , vol.129 , Issue.5 , pp. 1165-1173
    • Wu, J.1    Nihal, M.2    Siddiqui, J.3    Vonderheid, E.C.4    Wood, G.S.5
  • 70
    • 0033842372 scopus 로고    scopus 로고
    • Expression of Fas and Fas-ligand in primary cutaneous T-cell lymphoma (CTCL): Association between lack of Fas expression and aggressive types of CTCL
    • Zoi-Toli O, Vermeer MH, De Vries E, Van Beek P, Meijer CJ, Willemze R. Expression of Fas and Fas-ligand in primary cutaneous T-cell lymphoma (CTCL): association between lack of Fas expression and aggressive types of CTCL. Br J Dermatol. 2000;143(2):313-319.
    • (2000) Br J Dermatol. , vol.143 , Issue.2 , pp. 313-319
    • Zoi-Toli, O.1    Vermeer, M.H.2    De Vries, E.3    Van Beek, P.4    Meijer, C.J.5    Willemze, R.6
  • 71
    • 77949496219 scopus 로고    scopus 로고
    • Downregulation of Fas gene expression in Sézary syndrome is associated with promoter hypermethylation
    • Jones CL, Wain EM, Chu CC, et al. Downregulation of Fas gene expression in Sézary syndrome is associated with promoter hypermethylation. J Invest Dermatol. 2010;130(4):1116-1125.
    • (2010) J Invest Dermatol. , vol.130 , Issue.4 , pp. 1116-1125
    • Jones, C.L.1    Wain, E.M.2    Chu, C.C.3
  • 73
    • 84915818510 scopus 로고    scopus 로고
    • Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progression
    • Netchiporouk E, Litvinov IV, Moreau L, Gilbert M, Sasseville D, Duvic M. Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progression. Cell Cycle. 2014;13(21):3331-3335.
    • (2014) Cell Cycle , vol.13 , Issue.21 , pp. 3331-3335
    • Netchiporouk, E.1    Litvinov, I.V.2    Moreau, L.3    Gilbert, M.4    Sasseville, D.5    Duvic, M.6
  • 74
    • 0036464691 scopus 로고    scopus 로고
    • Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3
    • Nielsen M, Nissen MH, Gerwien J, et al. Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3. Blood. 2002;99(3):973-977.
    • (2002) Blood , vol.99 , Issue.3 , pp. 973-977
    • Nielsen, M.1    Nissen, M.H.2    Gerwien, J.3
  • 76
    • 84867815120 scopus 로고    scopus 로고
    • STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia
    • Jerez A, Clemente MJ, Makishima H, et al. STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia. Blood. 2012;120(15):3048-3057.
    • (2012) Blood , vol.120 , Issue.15 , pp. 3048-3057
    • Jerez, A.1    Clemente, M.J.2    Makishima, H.3
  • 77
    • 84928015700 scopus 로고    scopus 로고
    • Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma
    • Crescenzo R, Abate F, Lasorsa E, et al; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium "Genetics-Driven Targeted Management of Lymphoid Malignancies". Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma. Cancer Cell. 2015;27(4):516-532.
    • (2015) Cancer Cell. , vol.27 , Issue.4 , pp. 516-532
    • Crescenzo, R.1    Abate, F.2    Lasorsa, E.3
  • 78
    • 84908161000 scopus 로고    scopus 로고
    • Revisiting STAT3 signalling in cancer: New and unexpected biological functions
    • Yu H, Lee H, Herrmann A, Buettner R, Jove R. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer. 2014;14(11):736-746.
    • (2014) Nat Rev Cancer , vol.14 , Issue.11 , pp. 736-746
    • Yu, H.1    Lee, H.2    Herrmann, A.3    Buettner, R.4    Jove, R.5
  • 79
    • 84865197558 scopus 로고    scopus 로고
    • Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters
    • Lemonnier F, Couronné L, Parrens M, et al. Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters. Blood. 2012;120(7):1466-1469.
    • (2012) Blood , vol.120 , Issue.7 , pp. 1466-1469
    • Lemonnier, F.1    Couronné, L.2    Parrens, M.3
  • 80
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363(25):2424-2433.
    • (2010) N Engl J Med. , vol.363 , Issue.25 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 81
    • 84857575341 scopus 로고    scopus 로고
    • IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma
    • Cairns RA, Iqbal J, Lemonnier F, et al. IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma. Blood. 2012;119(8):1901-1903.
    • (2012) Blood , vol.119 , Issue.8 , pp. 1901-1903
    • Cairns, R.A.1    Iqbal, J.2    Lemonnier, F.3
  • 82
    • 21244458051 scopus 로고    scopus 로고
    • Epigenetic profiling of cutaneous T-cell lymphoma: Promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73
    • van Doorn R, Zoutman WH, Dijkman R, et al. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. J Clin Oncol. 2005;23(17):3886-3896.
    • (2005) J Clin Oncol. , vol.23 , Issue.17 , pp. 3886-3896
    • Van Doorn, R.1    Zoutman, W.H.2    Dijkman, R.3
  • 83
    • 77954879663 scopus 로고    scopus 로고
    • Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T-cell lymphoma
    • Whittaker SJ, Demierre MF, Kim EJ, et al. Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T-cell lymphoma. J Clin Oncol. 2010;28(29):4485-4491.
    • (2010) J Clin Oncol. , vol.28 , Issue.29 , pp. 4485-4491
    • Whittaker, S.J.1    Demierre, M.F.2    Kim, E.J.3
  • 84
    • 84920670383 scopus 로고    scopus 로고
    • Targeted mutational profiling of peripheral T-cell lymphoma not otherwise specified highlights new mechanisms in a heterogeneous pathogenesis
    • Schatz JH, Horwitz SM, Teruya-Feldstein J, et al. Targeted mutational profiling of peripheral T-cell lymphoma not otherwise specified highlights new mechanisms in a heterogeneous pathogenesis. Leukemia. 2015;29(1):237-241.
    • (2015) Leukemia , vol.29 , Issue.1 , pp. 237-241
    • Schatz, J.H.1    Horwitz, S.M.2    Teruya-Feldstein, J.3
  • 85
    • 84941210381 scopus 로고    scopus 로고
    • Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States
    • Hopp L, Löffler-Wirth H, Binder H. Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States. Genes (Basel). 2015;6(3):812-840.
    • (2015) Genes (Basel) , vol.6 , Issue.3 , pp. 812-840
    • Hopp, L.1    Löffler-Wirth, H.2    Binder, H.3
  • 87
    • 0038193611 scopus 로고    scopus 로고
    • Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis
    • Lee DH, Pfeifer GP. Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis. J Biol Chem. 2003;278(12):10314-10321.
    • (2003) J Biol Chem. , vol.278 , Issue.12 , pp. 10314-10321
    • Lee, D.H.1    Pfeifer, G.P.2
  • 88
    • 77956270426 scopus 로고    scopus 로고
    • Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: A biologic rationale for their distinct clinical behaviors
    • Campbell JJ, Clark RA, Watanabe R, Kupper TS. Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors. Blood. 2010;116(5):767-771.
    • (2010) Blood , vol.116 , Issue.5 , pp. 767-771
    • Campbell, J.J.1    Clark, R.A.2    Watanabe, R.3    Kupper, T.S.4


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