-
1
-
-
80053571383
-
Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)
-
Wong, H.K., Mishra, A., Hake, T. & Porcu, P. Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome). Br. J. Haematol. 155, 150-166 (2011).
-
(2011)
Br. J. Haematol.
, vol.155
, pp. 150-166
-
-
Wong, H.K.1
Mishra, A.2
Hake, T.3
Porcu, P.4
-
2
-
-
79952182407
-
High-throughput mutation profling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/ MEK signaling cascade
-
Kiessling, M.K. et al. High-throughput mutation profling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/ MEK signaling cascade. Blood 117, 2433-2440 (2011).
-
(2011)
Blood
, vol.117
, pp. 2433-2440
-
-
Kiessling, M.K.1
-
3
-
-
84897520067
-
PLCG1 mutations in cutaneous T-cell lymphomas
-
Vaqué, J.P. et al. PLCG1 mutations in cutaneous T-cell lymphomas. Blood 123, 2034-2043 (2014).
-
(2014)
Blood
, vol.123
, pp. 2034-2043
-
-
Vaqué, J.P.1
-
4
-
-
84883768106
-
Regulation of PI-3-kinase and Akt signaling in T lymphocytes and other cells by TNFR family molecules
-
So, T. & Croft, M. Regulation of PI-3-kinase and Akt signaling in T lymphocytes and other cells by TNFR family molecules. Front. Immunol. 4, 139 (2013).
-
(2013)
Front. Immunol.
, vol.4
, pp. 139
-
-
So, T.1
Croft, M.2
-
5
-
-
84868149174
-
Transcriptome sequencing in Sezary syndrome identifes Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts
-
Lee, C.S. et al. Transcriptome sequencing in Sezary syndrome identifes Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood 120, 3288-3297 (2012).
-
(2012)
Blood
, vol.120
, pp. 3288-3297
-
-
Lee, C.S.1
-
6
-
-
84930726139
-
FACTERA: A practical method for the discovery of genomic rearrangements at breakpoint resolution
-
Newman, A.M. et al. FACTERA: a practical method for the discovery of genomic rearrangements at breakpoint resolution. Bioinformatics 30, 3390-3393 (2014).
-
(2014)
Bioinformatics
, vol.30
, pp. 3390-3393
-
-
Newman, A.M.1
-
7
-
-
0028033909
-
Heterogeneous chromosomal aberrations generate 3′ truncations of the NFKB2/lyt-10 gene in lymphoid malignancies
-
Migliazza, A. et al. Heterogeneous chromosomal aberrations generate 3′ truncations of the NFKB2/lyt-10 gene in lymphoid malignancies. Blood 84, 3850-3860 (1994).
-
(1994)
Blood
, vol.84
, pp. 3850-3860
-
-
Migliazza, A.1
-
8
-
-
0028360163
-
Rearranged NFKB2 gene in the HUT78 T-lymphoma cell line codes for a constitutively nuclear factor lacking transcriptional repressor functions
-
Zhang, J., Chang, C.C., Lombardi, L. & Dalla-Favera, R. Rearranged NFKB2 gene in the HUT78 T-lymphoma cell line codes for a constitutively nuclear factor lacking transcriptional repressor functions. Oncogene 9, 1931-1937 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 1931-1937
-
-
Zhang, J.1
Chang, C.C.2
Lombardi, L.3
Dalla-Favera, R.4
-
9
-
-
84866363110
-
Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas
-
Vasmatzis, G. et al. Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas. Blood 120, 2280-2289 (2012).
-
(2012)
Blood
, vol.120
, pp. 2280-2289
-
-
Vasmatzis, G.1
-
10
-
-
84925545111
-
Clinical blockade of PD1 and LAG3-potential mechanisms of action
-
Nguyen, L.T. & Ohashi, P.S. Clinical blockade of PD1 and LAG3-potential mechanisms of action. Nat. Rev. Immunol. 15, 45-56 (2015).
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 45-56
-
-
Nguyen, L.T.1
Ohashi, P.S.2
-
11
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi, A. & Dixit, V.M. Death receptors: signaling and modulation. Science 281, 1305-1308 (1998).
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
12
-
-
84862502741
-
Positive conversion of negative signaling of CTLA4 potentiates antitumor effcacy of adoptive T-cell therapy in murine tumor models
-
Shin, J.H. et al. Positive conversion of negative signaling of CTLA4 potentiates antitumor effcacy of adoptive T-cell therapy in murine tumor models. Blood 119, 5678-5687 (2012).
-
(2012)
Blood
, vol.119
, pp. 5678-5687
-
-
Shin, J.H.1
-
13
-
-
84255197842
-
Cancer immunotherapy comes of age
-
Mellman, I., Coukos, G. & Dranoff, G. Cancer immunotherapy comes of age. Nature 480, 480-489 (2011).
-
(2011)
Nature
, vol.480
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
14
-
-
84971513662
-
Personalized treatment of Sezary syndrome by targeting a novel CTLA4:CD28 fusion
-
Sekulic, A. et al. Personalized treatment of Sezary syndrome by targeting a novel CTLA4:CD28 fusion. Mol. Genet. Genomic Med. 3, 130-136 (2015).
-
(2015)
Mol. Genet. Genomic Med.
, vol.3
, pp. 130-136
-
-
Sekulic, A.1
-
15
-
-
84859072803
-
Signal transduction by tumor necrosis factor receptors
-
Cabal-Hierro, L. & Lazo, P.S. Signal transduction by tumor necrosis factor receptors. Cell. Signal. 24, 1297-1305 (2012).
-
(2012)
Cell. Signal.
, vol.24
, pp. 1297-1305
-
-
Cabal-Hierro, L.1
Lazo, P.S.2
-
16
-
-
59449092607
-
Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome
-
van Doorn, R. et al. Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome. Blood 113, 127-136 (2009).
-
(2009)
Blood
, vol.113
, pp. 127-136
-
-
Van Doorn, R.1
-
17
-
-
84863334213
-
Circulating levels of TNF receptor II are prognostic for patients with peripheral T-cell non-Hodgkin lymphoma
-
Heemann, C. et al. Circulating levels of TNF receptor II are prognostic for patients with peripheral T-cell non-Hodgkin lymphoma. Clin. Cancer Res. 18, 3637-3647 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 3637-3647
-
-
Heemann, C.1
-
18
-
-
84856087480
-
Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients
-
Lin, W.M. et al. Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients. J. Invest. Dermatol. 132, 188-197 (2012).
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 188-197
-
-
Lin, W.M.1
-
19
-
-
79959537254
-
NF-κB signal triggering and termination by tumor necrosis factor receptor 2
-
Rodríguez, M. et al. NF-κB signal triggering and termination by tumor necrosis factor receptor 2. J. Biol. Chem. 286, 22814-22824 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22814-22824
-
-
Rodríguez, M.1
-
20
-
-
34948833649
-
Phase II trial of proteasome inhibitor bortezomib in patients with relapsed or refractory cutaneous T-cell lymphoma
-
Zinzani, P.L. et al. Phase II trial of proteasome inhibitor bortezomib in patients with relapsed or refractory cutaneous T-cell lymphoma. J. Clin. Oncol. 25, 4293-4297 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 4293-4297
-
-
Zinzani, P.L.1
-
21
-
-
0347505003
-
CD28-mediated co-stimulation: A quantitative support for TCR signalling
-
Acuto, O. & Michel, F. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3, 939-951 (2003).
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
22
-
-
77949587649
-
Fast and accurate long-read alignment with Burrows-Wheeler transform
-
Li, H. & Durbin, R. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26, 589-595 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 589-595
-
-
Li, H.1
Durbin, R.2
-
23
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
DePristo, M.A. et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet. 43, 491-498 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 491-498
-
-
DePristo, M.A.1
-
24
-
-
69949122158
-
VarScan: Variant detection in massively parallel sequencing of individual and pooled samples
-
Koboldt, D.C. et al. VarScan: variant detection in massively parallel sequencing of individual and pooled samples. Bioinformatics 25, 2283-2285 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 2283-2285
-
-
Koboldt, D.C.1
-
25
-
-
79959671356
-
SeqGene: A comprehensive software solution for mining exome- and transcriptome-sequencing data
-
Deng, X. SeqGene: a comprehensive software solution for mining exome- and transcriptome-sequencing data. BMC Bioinformatics 12, 267 (2011).
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 267
-
-
Deng, X.1
-
26
-
-
70249111091
-
Targeted capture and massively parallel sequencing of 12 human exomes
-
Ng, S.B. et al. Targeted capture and massively parallel sequencing of 12 human exomes. Nature 461, 272-276 (2009).
-
(2009)
Nature
, vol.461
, pp. 272-276
-
-
Ng, S.B.1
-
27
-
-
84881613239
-
DbNSFP v2.0: A database of human non-synonymous SNVs and their functional predictions and annotations
-
Liu, X., Jian, X. & Boerwinkle, E. dbNSFP v2.0: a database of human non-synonymous SNVs and their functional predictions and annotations. Hum. Mutat. 34, E2393-E2402 (2013).
-
(2013)
Hum. Mutat.
, vol.34
, pp. E2393-E2402
-
-
Liu, X.1
Jian, X.2
Boerwinkle, E.3
-
28
-
-
84876996918
-
TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
-
Kim, D. et al. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14, R36 (2013).
-
(2013)
Genome Biol.
, vol.14
, pp. R36
-
-
Kim, D.1
-
29
-
-
34249317298
-
Gene set enrichment analysis (GSEA) for interpreting gene expression profles
-
Shi, J. & Walker, M.G. Gene set enrichment analysis (GSEA) for interpreting gene expression profles. Curr. Bioinformatics 2, 133-137 (2007).
-
(2007)
Curr. Bioinformatics
, vol.2
, pp. 133-137
-
-
Shi, J.1
Walker, M.G.2
-
30
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
|