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Volumn 46, Issue 2, 2014, Pages 166-170

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

(21)  Palomero, Teresa a,b   Couronné, Lucile a   Khiabanian, Hossein a   Kim, Mi Yeon a   Ambesi Impiombato, Alberto a   Perez Garcia, Arianne a   Carpenter, Zachary a   Abate, Francesco a,c   Allegretta, Maddalena a   Haydu, J Erika a   Jiang, Xiaoyu d   Lossos, Izidore S d,e   Nicolas, Concha f   Balbin, Milagros g   Bastard, Christian h   Bhagat, Govind b   Piris, Miguel A i   Campo, Elias j,k   Bernard, Olivier A l,m   Rabadan, Raul a   more..


Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DNA; DNA METHYLTRANSFERASE 3A; GUANINE EXCHANGE FACTOR; ISOCITRATE DEHYDROGENASE 2; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; PROTEIN; PROTEIN KINASE FYN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84895829862     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2873     Document Type: Article
Times cited : (515)

References (36)
  • 1
    • 84859919632 scopus 로고    scopus 로고
    • The aggressive peripheral T-cell lymphomas: 2012 update on diagnosis, risk stratification, and management
    • Armitage, J.O. The aggressive peripheral T-cell lymphomas: 2012 update on diagnosis, risk stratification, and management. Am. J. Hematol. 87, 511-519 (2012
    • (2012) Am. J. Hematol , vol.87 , pp. 511-519
    • Armitage, J.O.1
  • 2
    • 0036228950 scopus 로고    scopus 로고
    • Peripheral T-cell lymphoma (excluding anaplastic large-cell lymphoma): Results from the Non-Hodgkin's Lymphoma Classification Project
    • Rüdiger, T. et al. Peripheral T-cell lymphoma (excluding anaplastic large-cell lymphoma): Results from the Non-Hodgkin's Lymphoma Classification Project. Ann. Oncol. 13, 140-149 (2002
    • (2002) Ann. Oncol , vol.13 , pp. 140-149
    • Rüdiger, T.1
  • 3
    • 33749240350 scopus 로고    scopus 로고
    • Coupling receptor tyrosine kinases to Rho GTPases-GEFs what's the link
    • Schiller, M.R. Coupling receptor tyrosine kinases to Rho GTPases-GEFs what's the link. Cell. Signal. 18, 1834-1843 (2006
    • (2006) Cell. Signal , vol.18 , pp. 1834-1843
    • Schiller, M.R.1
  • 4
    • 0034644537 scopus 로고    scopus 로고
    • Ras and Rho GTPases: A family reunion
    • Bar-Sagi, D. & Hall, A. Ras and Rho GTPases: A family reunion. Cell 103, 227-238 (2000
    • (2000) Cell , vol.103 , pp. 227-238
    • Bar-Sagi, D.1    Hall, A.2
  • 5
    • 44449178868 scopus 로고    scopus 로고
    • Rho GTPases in cancer cell biology
    • Vega, F.M. & Ridley, A.J. Rho GTPases in cancer cell biology. FEBS Lett. 582, 2093-2101 (2008
    • (2008) FEBS Lett , vol.582 , pp. 2093-2101
    • Vega, F.M.1    Ridley, A.J.2
  • 6
    • 84880162772 scopus 로고    scopus 로고
    • Signaling networks of Rho GTPases in cell motility
    • Hanna, S. & El-Sibai, M. Signaling networks of Rho GTPases in cell motility. Cell. Signal. 25, 1955-1961 (2013
    • (2013) Cell. Signal , vol.25 , pp. 1955-1961
    • Hanna, S.1    El-Sibai, M.2
  • 7
    • 84870209800 scopus 로고    scopus 로고
    • Rho family GTPases
    • Hall, A. Rho family GTPases. Biochem. Soc. Trans. 40, 1378-1382 (2012
    • (2012) Biochem. Soc. Trans , vol.40 , pp. 1378-1382
    • Hall, A.1
  • 8
    • 0038521337 scopus 로고    scopus 로고
    • Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 Åresolution
    • Longenecker, K. et al. Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 Å resolution. Acta Crystallogr. D Biol. Crystallogr. 59, 876-880 (2003
    • (2003) Acta Crystallogr. D Biol. Crystallogr , vol.59 , pp. 876-880
    • Longenecker, K.1
  • 9
    • 0033602359 scopus 로고    scopus 로고
    • A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts
    • Mayer, T., Meyer, M., Janning, A., Schiedel, A.C. & Barnekow, A. A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts. Oncogene 18, 2117-2128 (1999
    • (1999) Oncogene , vol.18 , pp. 2117-2128
    • Mayer, T.1    Meyer, M.2    Janning, A.3    Schiedel, A.C.4    Barnekow, A.5
  • 10
    • 0028820587 scopus 로고
    • Rho family GTPases regulate p38 mitogen-Activated protein kinase through the downstream mediator Pak1
    • Zhang, S. et al. Rho family GTPases regulate p38 mitogen-Activated protein kinase through the downstream mediator Pak1. J. Biol. Chem. 270, 23934-23936 (1995
    • (1995) J. Biol. Chem , vol.270 , pp. 23934-23936
    • Zhang, S.1
  • 11
    • 0033566068 scopus 로고    scopus 로고
    • Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line
    • Ghosh, P.M. et al. Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. Oncogene 18, 4120-4130 (1999
    • (1999) Oncogene , vol.18 , pp. 4120-4130
    • Ghosh, P.M.1
  • 12
    • 0032520791 scopus 로고    scopus 로고
    • Role of the Rho GTPase in bradykinin-stimulated nuclear factor-?B activation and IL-1β gene expression in cultured human epithelial cells
    • Pan, Z.K. et al. Role of the Rho GTPase in bradykinin-stimulated nuclear factor-?B activation and IL-1β gene expression in cultured human epithelial cells. J. Immunol. 160, 3038-3045 (1998
    • (1998) J. Immunol , vol.160 , pp. 3038-3045
    • Pan, Z.K.1
  • 13
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
    • Reid, T. et al. Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J. Biol. Chem. 271, 13556-13560 (1996
    • (1996) J. Biol. Chem , vol.271 , pp. 13556-13560
    • Reid, T.1
  • 14
    • 32144453465 scopus 로고    scopus 로고
    • Analysis of activated GAPs and GEFs in cell lysates
    • García-Mata, R. et al. Analysis of activated GAPs and GEFs in cell lysates. Methods Enzymol. 406, 425-437 (2006
    • (2006) Methods Enzymol , vol.406 , pp. 425-437
    • García-Mata, R.1
  • 15
    • 84855718050 scopus 로고    scopus 로고
    • TET2 and DNMT3A mutations in human T-cell lymphoma
    • Couronné, L., Bastard, C. & Bernard, O.A. TET2 and DNMT3A mutations in human T-cell lymphoma. N. Engl. J. Med. 366, 95-96 (2012
    • (2012) N. Engl. J. Med , vol.366 , pp. 95-96
    • Couronné, L.1    Bastard, C.2    Bernard, O.A.3
  • 16
    • 79960062301 scopus 로고    scopus 로고
    • TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
    • Quivoron, C. et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20, 25-38 (2011
    • (2011) Cancer Cell , vol.20 , pp. 25-38
    • Quivoron, C.1
  • 17
    • 84857575341 scopus 로고    scopus 로고
    • IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma
    • Cairns, R.A. et al. IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma. Blood 119, 1901-1903 (2012
    • (2012) Blood , vol.119 , pp. 1901-1903
    • Cairns, R.A.1
  • 18
    • 7944231534 scopus 로고    scopus 로고
    • Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation
    • Palacios, E.H. & Weiss, A. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene 23, 7990-8000 (2004
    • (2004) Oncogene , vol.23 , pp. 7990-8000
    • Palacios, E.H.1    Weiss, A.2
  • 19
    • 80052610431 scopus 로고    scopus 로고
    • Dasatinib: A review of its use in the treatment of chronic myeloid leukaemia and Philadelphia chromosome-positive acute lymphoblastic leukaemia
    • McCormack, P.L. & Keam, S.J. Dasatinib: A review of its use in the treatment of chronic myeloid leukaemia and Philadelphia chromosome-positive acute lymphoblastic leukaemia. Drugs 71, 1771-1795 (2011
    • (2011) Drugs , vol.71 , pp. 1771-1795
    • McCormack, P.L.1    Keam, S.J.2
  • 20
    • 77955713928 scopus 로고    scopus 로고
    • Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia
    • Harr, M.W. et al. Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia. Cell Death Differ. 17, 1381-1391 (2010
    • (2010) Cell Death Differ , vol.17 , pp. 1381-1391
    • Harr, M.W.1
  • 21
    • 0031954631 scopus 로고    scopus 로고
    • MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis
    • Widmann, C., Gerwins, P., Johnson, N.L., Jarpe, M.B. & Johnson, G.L. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol. Cell. Biol. 18, 2416-2429 (1998
    • (1998) Mol. Cell. Biol , vol.18 , pp. 2416-2429
    • Widmann, C.1    Gerwins, P.2    Johnson, N.L.3    Jarpe, M.B.4    Johnson, G.L.5
  • 22
    • 77949587649 scopus 로고    scopus 로고
    • Fast and accurate long-read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26, 589-595 (2010
    • (2010) Bioinformatics , vol.26 , pp. 589-595
    • Li, H.1    Durbin, R.2
  • 23
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • Langmead, B. & Salzberg, S.L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012
    • (2012) Nat. Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 24
    • 84867051939 scopus 로고    scopus 로고
    • Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
    • Schmitz, R. et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 490, 116-120 (2012
    • (2012) Nature , vol.490 , pp. 116-120
    • Schmitz, R.1
  • 25
    • 68149176840 scopus 로고    scopus 로고
    • Chimeric transcript discovery by paired-end transcriptome sequencing
    • Maher, C.A. et al. Chimeric transcript discovery by paired-end transcriptome sequencing. Proc. Natl. Acad. Sci. USA 106, 12353-12358 (2009
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 12353-12358
    • Maher, C.A.1
  • 26
    • 79957829805 scopus 로고    scopus 로고
    • DeFuse: An algorithm for gene fusion discovery in tumor RNA-Seq data
    • McPherson, A. et al. deFuse: An algorithm for gene fusion discovery in tumor RNA-Seq data. PLoS Comput. Biol. 7, e1001138 (2011
    • (2011) PLoS Comput. Biol , vol.7
    • McPherson, A.1
  • 27
    • 4444221565 scopus 로고    scopus 로고
    • UCSF Chimera-A visualization system for exploratory research and analysis
    • Pettersen, E.F. et al. UCSF Chimera-A visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612 (2004
    • (2004) J. Comput. Chem , vol.25 , pp. 1605-1612
    • Pettersen, E.F.1
  • 28
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • Altschul, S.F. et al. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25, 3389-3402 (1997
    • (1997) Nucleic Acids Res , vol.25 , pp. 3389-3402
    • Altschul, S.F.1
  • 29
    • 77954065271 scopus 로고    scopus 로고
    • I-TASSER: A unified platform for automated protein structure and function prediction
    • Roy, A., Kucukural, A. & Zhang, Y. I-TASSER: A unified platform for automated protein structure and function prediction. Nat. Protoc. 5, 725-738 (2010
    • (2010) Nat. Protoc , vol.5 , pp. 725-738
    • Roy, A.1    Kucukural, A.2    Zhang, Y.3
  • 30
    • 79959942908 scopus 로고    scopus 로고
    • SDM-A server for predicting effects of mutations on protein stability and malfunction
    • Worth, C.L., Preissner, R. & Blundell, T.L. SDM-A server for predicting effects of mutations on protein stability and malfunction. Nucleic Acids Res. 39, W215-W222 (2011
    • (2011) Nucleic Acids Res , vol.39
    • Worth, C.L.1    Preissner, R.2    Blundell, T.L.3
  • 31
    • 0034737484 scopus 로고    scopus 로고
    • Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas
    • Subauste, M.C. et al. Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas. J. Biol. Chem. 275, 9725-9733 (2000
    • (2000) J. Biol. Chem , vol.275 , pp. 9725-9733
    • Subauste, M.C.1
  • 32
    • 0035851913 scopus 로고    scopus 로고
    • EGF-R signaling through Fyn kinase disrupts the function of integrin a6β4 at hemidesmosomes: Role in epithelial cell migration and carcinoma invasion
    • Mariotti, A. et al. EGF-R signaling through Fyn kinase disrupts the function of integrin a6β4 at hemidesmosomes: Role in epithelial cell migration and carcinoma invasion. J. Cell Biol. 155, 447-458 (2001
    • (2001) J. Cell Biol , vol.155 , pp. 447-458
    • Mariotti, A.1
  • 33
    • 54049093604 scopus 로고    scopus 로고
    • Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling
    • Kamanova, J. et al. Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling. J. Immunol. 181, 5587-5597 (2008
    • (2008) J. Immunol , vol.181 , pp. 5587-5597
    • Kamanova, J.1
  • 34
    • 80052020183 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase is a signaling protein in long-Term tolerance by dendritic cells
    • Pallotta, M.T. et al. Indoleamine 2,3-dioxygenase is a signaling protein in long-Term tolerance by dendritic cells. Nat. Immunol. 12, 870-878 (2011
    • (2011) Nat. Immunol , vol.12 , pp. 870-878
    • Pallotta, M.T.1
  • 35
    • 80555142897 scopus 로고    scopus 로고
    • Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
    • Schenk, S. et al. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J. Clin. Invest. 121, 4281-4288 (2011
    • (2011) J. Clin. Invest , vol.121 , pp. 4281-4288
    • Schenk, S.1
  • 36
    • 3142730924 scopus 로고    scopus 로고
    • Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells
    • Wang, Q. et al. Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells. J. Biol. Chem. 279, 28831-28834 (2004.
    • (2004) J. Biol. Chem , vol.279 , pp. 28831-28834
    • Wang, Q.1


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