메뉴 건너뛰기




Volumn 120, Issue 15, 2012, Pages 3048-3057

STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN INHIBITOR; STAT3 PROTEIN; STAT3 PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 84867815120     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-06-435297     Document Type: Article
Times cited : (353)

References (38)
  • 1
    • 0021909118 scopus 로고
    • Leukemia of large granular lymphocytes: Association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia, and hemolytic anemia
    • Loughran TP Jr, Kadin ME, Starkebaum G, et al. Leukemia of large granular lymphocytes: association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia, and hemolytic anemia. Ann Intern Med. 1985;102(2):169-175. (Pubitemid 15157163)
    • (1985) Annals of Internal Medicine , vol.102 , Issue.2 , pp. 169-175
    • Loughran Jr., T.P.1    Kadin, M.E.2    Starkebaum, G.3
  • 2
    • 0027300176 scopus 로고
    • Clonal diseases of large granular lymphocytes
    • Loughran TP Jr. Clonal diseases of large granular lymphocytes. Blood. 1993;82(1):1-14.
    • (1993) Blood , vol.82 , Issue.1 , pp. 1-14
    • Loughran Jr., T.P.1
  • 3
    • 53249123632 scopus 로고    scopus 로고
    • International Agency for Research on Cancer, World Health Organization. (4th Ed). Lyon, France: International Agency for Research on Cancer
    • Swerdlow SH, International Agency for Research on Cancer, World Health Organization. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (4th Ed). Lyon, France: International Agency for Research on Cancer; 2008.
    • (2008) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
    • Swerdlow, S.H.1
  • 5
    • 77956840179 scopus 로고    scopus 로고
    • Analysis of a French cohort of patients with large granular lymphocyte leukemia: A report on 229 cases
    • Bareau B, Rey J, Hamidou M, et al. Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases. Haematologica. 2010;95(9):1534-1541.
    • (2010) Haematologica , vol.95 , Issue.9 , pp. 1534-1541
    • Bareau, B.1    Rey, J.2    Hamidou, M.3
  • 6
    • 58149388342 scopus 로고    scopus 로고
    • Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling
    • Epling-Burnette PK, Sokol L, Chen X, et al. Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling. Blood. 2008;112(12):4694-4698.
    • (2008) Blood , vol.112 , Issue.12 , pp. 4694-4698
    • Epling-Burnette, P.K.1    Sokol, L.2    Chen, X.3
  • 7
    • 0027976958 scopus 로고
    • Clonal populations of T cells in normal elderly humans: The T cell equivalent to "benign monoclonal gammapathy."
    • Posnett DN, Sinha R, Kabak S, Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy."J Exp Med. 1994;179(2):609-618.
    • (1994) J Exp Med , vol.179 , Issue.2 , pp. 609-618
    • Posnett, D.N.1    Sinha, R.2    Kabak, S.3    Russo, C.4
  • 8
    • 0038210246 scopus 로고    scopus 로고
    • Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94:NKG2C/E and NKD2D killer cell receptors
    • DOI 10.1182/blood-2002-08-2408
    • Bigouret V, Hoffmann T, Arlettaz L, et al. Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94:NKG2C/E and NKD2D killer cell receptors. Blood. 2003;101(8):3198-3204. (Pubitemid 36858015)
    • (2003) Blood , vol.101 , Issue.8 , pp. 3198-3204
    • Bigouret, V.1    Hoffmann, T.2    Arlettaz, L.3    Villard, J.4    Colonna, M.5    Ticheli, A.6    Gratwohl, A.7    Samii, K.8    Chapuis, B.9    Rufer, N.10    Roosnek, E.11
  • 9
    • 0030668265 scopus 로고    scopus 로고
    • Routine diagnosis of large granular lymphocytic leukaemia by Southern blot and polymerase chain reaction analysis of clonal T cell receptor gene rearrangements
    • Ryan DK, Alexander HD, Morris TC. Routine diagnosis of large granular lymphocytic leukaemia by Southern blot and polymerase chain reaction analysis of clonal T cell receptor gene rearrangement. Mol Pathol. 1997;50(2):77-81. (Pubitemid 27455007)
    • (1997) Journal of Clinical Pathology - Molecular Pathology , vol.50 , Issue.2 , pp. 77-81
    • Ryan, D.K.1
  • 11
    • 84861023172 scopus 로고    scopus 로고
    • Somatic STAT3 mutations in large granular lymphocytic leukemia
    • Koskela HL, Eldfors S, Ellonen P, et al. Somatic STAT3 mutations in large granular lymphocytic leukemia. N Engl J Med. 2012;366(20):1905-1913.
    • (2012) N Engl J Med , vol.366 , Issue.20 , pp. 1905-1913
    • Koskela, H.L.1    Eldfors, S.2    Ellonen, P.3
  • 12
    • 0031037361 scopus 로고    scopus 로고
    • The lymphoproliferative disease of granular lymphocytes: Updated criteria for diagnosis
    • Semenzato G, Zambello R, Starkebaum G, Oshimi K, Loughran TP Jr. The lymphoproliferative disease of granular lymphocytes: updated criteria for diagnosis. Blood. 1997;89(1):256-260. (Pubitemid 26428200)
    • (1997) Blood , vol.89 , Issue.1 , pp. 256-260
    • Semenzato, G.1    Zambello, R.2    Starkebaum, G.3    Oshimi, K.4    Loughran Jr., T.P.5
  • 13
    • 70349651353 scopus 로고    scopus 로고
    • Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia
    • Mohan SR, Clemente MJ, Afable M, et al. Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia. Haematologica. 2009;94(10):1407-1414.
    • (2009) Haematologica , vol.94 , Issue.10 , pp. 1407-1414
    • Mohan, S.R.1    Clemente, M.J.2    Afable, M.3
  • 15
    • 0035412374 scopus 로고    scopus 로고
    • Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations
    • Langerak AW, van Den Beemd R, Wolvers-Tettero IL, et al. Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations. Blood. 2001;98(1):165-173.
    • (2001) Blood , vol.98 , Issue.1 , pp. 165-173
    • Langerak, A.W.1    Van Den Beemd, R.2    Wolvers-Tettero, I.L.3
  • 16
    • 1542377673 scopus 로고    scopus 로고
    • Flow Cytometric Assessment of TCR-Vbeta Expression in the Evaluation of Peripheral Blood Involvement by T-Cell Lymphoproliferative Disorders: A Comparison with Conventional T-Cell Immunophenotyping and Molecular Genetic Techniques
    • DOI 10.1309/3A32-DTVM-H640-M2QA
    • Morice WG, Kimlinger T, Katzmann JA, et al. Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques. Am J Clin Pathol. 2004;121(3):373-383. (Pubitemid 38298171)
    • (2004) American Journal of Clinical Pathology , vol.121 , Issue.3 , pp. 373-383
    • Morice, W.G.1    Kimlinger, T.2    Katzmann, J.A.3    Lust, J.A.4    Heimgartner, P.J.5    Halling, K.C.6    Hanson, C.A.7
  • 18
    • 30144446015 scopus 로고    scopus 로고
    • Interferon-gamma-induced gene expression in CD34 cells: Identification of pathologic cytokine-specific signature profiles
    • DOI 10.1182/blood-2005-05-1884
    • ZengW, Miyazato A, Chen G, Kajigaya S, Young NS, Maciejewski JP. Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles. Blood. 2006;107(1):167-175. (Pubitemid 43053539)
    • (2006) Blood , vol.107 , Issue.1 , pp. 167-175
    • Zeng, W.1    Miyazato, A.2    Chen, G.3    Kajigaya, S.4    Young, N.S.5    Maciejewski, J.P.6
  • 19
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen Z, Zhong Z, Darnell JE Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell. 1995;82(2):241-250.
    • (1995) Cell , vol.82 , Issue.2 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 20
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer. 2009;9:798-809.
    • (2009) Nat Rev Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 21
  • 22
    • 0027230912 scopus 로고
    • Phenotypic diversity of natural killer (NK) populations in patients with NK-type lymphoproliferative disease of granular lymphocytes
    • Zambello R, Trentin L, Ciccone E, et al. Phenotypic diversity of natural killer (NK) populations in patients with NK-type lymphoproliferative disease of granular lymphocytes. Blood. 1993;81(9):2381-2385. (Pubitemid 23127074)
    • (1993) Blood , vol.81 , Issue.9 , pp. 2381-2385
    • Zambello, R.1    Trentin, L.2    Ciccone, E.3    Bulian, P.4    Agostini, C.5    Moretta, A.6    Moretta, L.7    Semenzato, G.8
  • 23
    • 1942456857 scopus 로고    scopus 로고
    • Dysregulated NK receptor expression in patients with lymphoproliferative disease of granular lymphocytes
    • DOI 10.1182/blood-2003-02-0400
    • Epling-Burnette PK, Painter JS, Chaurasia P, et al. Dysregulated NK receptor expression in patients with lymphoproliferative disease of granular lymphocytes. Blood. 2004;103(9):3431-3439. (Pubitemid 38525675)
    • (2004) Blood , vol.103 , Issue.9 , pp. 3431-3439
    • Epling-Burnette, P.K.1    Painter, J.S.2    Chaurasia, P.3    Bai, F.4    Wei, S.5    Djeu, J.Y.6    Loughran Jr., T.P.7
  • 24
    • 84855164715 scopus 로고    scopus 로고
    • Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia
    • Clemente MJ, Wlodarski MW, Makishima H, et al. Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia. Blood. 2011;118(16):4384-4393.
    • (2011) Blood , vol.118 , Issue.16 , pp. 4384-4393
    • Clemente, M.J.1    Wlodarski, M.W.2    Makishima, H.3
  • 25
    • 37349098725 scopus 로고    scopus 로고
    • Autocrine IL-6 Signaling: A Key Event in Tumorigenesis?
    • DOI 10.1016/j.ccr.2007.12.020, PII S1535610807003790
    • Grivennikov S, Karin M. Autocrine IL-6 signaling: a key event in tumorigenesis? Cancer Cell. 2008;13(1):7-9. (Pubitemid 350309747)
    • (2008) Cancer Cell , vol.13 , Issue.1 , pp. 7-9
    • Grivennikov, S.1    Karin, M.2
  • 26
    • 0038581774 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system
    • Sriuranpong V, Park JI, Amornphimoltham P, Patel V, Nelkin BD, Gutkind JS. Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system. Cancer Res. 2003;63(11):2948-2956. (Pubitemid 36667168)
    • (2003) Cancer Research , vol.63 , Issue.11 , pp. 2948-2956
    • Sriuranpong, V.1    Park, J.I.2    Amornphimoltham, P.3    Patel, V.4    Nelkin, B.D.5    Gutkind, J.S.6
  • 27
    • 0035042611 scopus 로고    scopus 로고
    • SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
    • DOI 10.1038/88225
    • Yoshikawa H, Matsubara K, Qian GS, et al. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growthsuppression activity. Nat Genet. 2001;28(1):29-35. (Pubitemid 32405812)
    • (2001) Nature Genetics , vol.28 , Issue.1 , pp. 29-35
    • Yoshikawa, H.1    Matsubara, K.2    Qian, G.-S.3    Jackson, P.4    Groopman, J.D.5    Manning, J.E.6    Harris, C.C.7    Herman, J.G.8
  • 28
    • 0035136846 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
    • Epling-Burnette PK, Liu JH, Catlett-Falcone R, et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest. 2001;107(3):351-362.
    • (2001) J Clin Invest , vol.107 , Issue.3 , pp. 351-362
    • Epling-Burnette, P.K.1    Liu, J.H.2    Catlett-Falcone, R.3
  • 33
    • 0034659136 scopus 로고    scopus 로고
    • Leukemia of large granular lymphocytes and rheumatoid arthritis
    • DOI 10.1016/S0002-9343(00)00386-7, PII S0002934300003867
    • Starkebaum G. Leukemia of large granular lymphocytes and rheumatoid arthritis. Am J Med. 2000;108(9):744-745. (Pubitemid 30621465)
    • (2000) American Journal of Medicine , vol.108 , Issue.9 , pp. 744-745
    • Starkebaum, G.1
  • 36
    • 62449202978 scopus 로고    scopus 로고
    • Cell death in rheumatoid arthritis
    • Korb A, Pavenstadt H, Pap T. Cell death in rheumatoid arthritis. Apoptosis. 2009;14(4):447-454.
    • (2009) Apoptosis , vol.14 , Issue.4 , pp. 447-454
    • Korb, A.1    Pavenstadt, H.2    Pap, T.3
  • 37
    • 35948995412 scopus 로고    scopus 로고
    • Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3
    • Kim NH, Lee MY, Park SJ, Choi JS, Oh MK, Kim IS. Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3. Immunology. 2007;122(4):607-614.
    • (2007) Immunology , vol.122 , Issue.4 , pp. 607-614
    • Kim, N.H.1    Lee, M.Y.2    Park, S.J.3    Choi, J.S.4    Oh, M.K.5    Kim, I.S.6
  • 38
    • 38349135720 scopus 로고    scopus 로고
    • Clonal regulatory T cells specific for a red blood cell autoantigen in human autoimmune hemolytic anemia
    • Ward FJ, Hall AM, Cairns LS, et al. Clonal regulatory T cells specific for a red blood cell autoantigen in human autoimmune hemolytic anemia. Blood. 2008;111(2):680-687.
    • (2008) Blood , vol.111 , Issue.2 , pp. 680-687
    • Ward, F.J.1    Hall, A.M.2    Cairns, L.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.