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Volumn 13, Issue 21, 2014, Pages 3331-3335

Deregulation in STAT signaling is important for cutaneous T-cell lymphoma (CTCL) pathogenesis and cancer progression

Author keywords

And STAT6; Cutaneous T cell lymphoma (CTCL); Mycosis fungoides; STAT3; STAT4; STAT5; S zary syndrome

Indexed keywords

CYCLIN D; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR BETA1; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 21; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 9; JANUS KINASE 1; JANUS KINASE 3; MICRORNA; MICRORNA 155; PROTEIN BCL 2; PROTEIN BCL X; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT4 PROTEIN; STAT5 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; STAT6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; VASCULOTROPIN; JANUS KINASE 2; MESSENGER RNA;

EID: 84915818510     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2014.965061     Document Type: Review
Times cited : (105)

References (37)
  • 3
    • 0042744782 scopus 로고    scopus 로고
    • Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: An expression profile study
    • PMID:12689942
    • Tracey L, Villuendas R, Dotor AM, Spiteri I, Ortiz P, Garcia JF, Peralto JL, Lawler M, Piris MA. Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: an expression profile study. Blood 2003; 102:1042-50; PMID:12689942; http://dx.doi.org/10.1182/blood- 2002-11-3574
    • (2003) Blood , vol.102 , pp. 1042-1050
    • Tracey, L.1    Villuendas, R.2    Dotor, A.M.3    Spiteri, I.4    Ortiz, P.5    Garcia, J.F.6    Peralto, J.L.7    Lawler, M.8    Piris, M.A.9
  • 4
    • 0033215166 scopus 로고    scopus 로고
    • Depressed IL-12-mediated signal transduction in T cells from patients with Sezary syndrome is associated with the absence of IL-12 receptor beta 2 mRNA and highly reduced levels of STAT4
    • Showe LC, Fox FE, Williams D, Au K, Niu Z, Rook AH. Depressed IL-12-mediated signal transduction in T cells from patients with Sezary syndrome is associated with the absence of IL-12 receptor beta 2 mRNA and highly reduced levels of STAT4. J Immunol 1999; 163:4073-9.
    • (1999) J Immunol , vol.163 , pp. 4073-4079
    • Showe, L.C.1    Fox, F.E.2    Williams, D.3    Au, K.4    Niu, Z.5    Rook, A.H.6
  • 6
    • 12444335268 scopus 로고    scopus 로고
    • Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma
    • PMID:12782714
    • Kari L, Loboda A, Nebozhyn M, Rook AH, Vonderheid EC, Nichols C, Virok D, Chang C, Horng WH, Johnston J, et al. Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma. J Exp Med 2003; 197:1477-88; PMID:12782714; http://dx.doi.org/10.1084/jem.20021726
    • (2003) J Exp Med , vol.197 , pp. 1477-1488
    • Kari, L.1    Loboda, A.2    Nebozhyn, M.3    Rook, A.H.4    Vonderheid, E.C.5    Nichols, C.6    Virok, D.7    Chang, C.8    Horng, W.H.9    Johnston, J.10
  • 7
    • 33645734738 scopus 로고    scopus 로고
    • Quantitative PCR on 5 genes reliably identifies CTCL patients with 5% to 99% circulating tumor cells with 90% accuracy
    • PMID:16403914
    • Nebozhyn M, Loboda A, Kari L, Rook AH, Vonderheid EC, Lessin S, et al. Quantitative PCR on 5 genes reliably identifies CTCL patients with 5% to 99% circulating tumor cells with 90% accuracy. Blood 2006; 107:3189-96; PMID:16403914; http://dx.doi.org/10.1182/blood-2005-07-2813
    • (2006) Blood , vol.107 , pp. 3189-3196
    • Nebozhyn, M.1    Loboda, A.2    Kari, L.3    Rook, A.H.4    Vonderheid, E.C.5    Lessin, S.6
  • 8
    • 4143079424 scopus 로고    scopus 로고
    • Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in Sezary syndrome identified by gene expression analysis
    • PMID:15313894
    • van Doorn R, Dijkman R, Vermeer MH, Out-Luiting JJ, van der Raaij-Helmer EM, Willemze R, Tensen CP. Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in Sezary syndrome identified by gene expression analysis. Cancer Res 2004; 64:5578-86; PMID:15313894; http://dx. doi.org/10.1158/0008-5472.CAN-04-1253
    • (2004) Cancer Res , vol.64 , pp. 5578-5586
    • Van Doorn, R.1    Dijkman, R.2    Vermeer, M.H.3    Out-Luiting, J.J.4    Van Der-Raaij-Helmer, E.M.5    Willemze, R.6    Tensen, C.P.7
  • 12
    • 34447129566 scopus 로고    scopus 로고
    • Transcription factor profiling shows new ways towards new treatment options of cutaneous T cell lymphomas
    • PMID:17630925
    • Dobbeling U. Transcription factor profiling shows new ways towards new treatment options of cutaneous T cell lymphomas. Curr Drug Discov Technol 2007; 4:24-30; PMID:17630925; http://dx.doi.org/10.2174/157016307781115467
    • (2007) Curr Drug Discov Technol , vol.4 , pp. 24-30
    • Dobbeling, U.1
  • 13
    • 0034792532 scopus 로고    scopus 로고
    • Constitutive and interleukin-7- and interleukin-15-stimulated DNA binding of STAT and novel factors in cutaneous T cell lymphoma cells
    • PMID:11564163
    • Qin JZ, Kamarashev J, Zhang CL, Dummer R, Burg G, Dobbeling U. Constitutive and interleukin-7- and interleukin-15-stimulated DNA binding of STAT and novel factors in cutaneous T cell lymphoma cells. J Invest Dermatol 2001; 117:583-9; PMID:11564163; http://dx.doi.org/10.1046/j.0022-202x.2001.01436.x
    • (2001) J Invest Dermatol , vol.117 , pp. 583-589
    • Qin, J.Z.1    Kamarashev, J.2    Zhang, C.L.3    Dummer, R.4    Burg, G.5    Dobbeling, U.6
  • 14
    • 0035525783 scopus 로고    scopus 로고
    • Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T-cell lymphoma cells
    • PMID:11675351
    • Qin JZ, Zhang CL, Kamarashev J, Dummer R, Burg G, Dobbeling U. Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T-cell lymphoma cells. Blood 2001; 98:2778-83; PMID:11675351; http://dx.doi.org/10.1182/blood. V98.9.2778
    • (2001) Blood , vol.98 , pp. 2778-2783
    • Qin, J.Z.1    Zhang, C.L.2    Kamarashev, J.3    Dummer, R.4    Burg, G.5    Dobbeling, U.6
  • 15
    • 84880541882 scopus 로고    scopus 로고
    • Connecting the dots in cutaneous T cell lymphoma (CTCL): STAT5 regulates malignant T cell proliferation via miR-155
    • PMID:23803726
    • Litvinov IV, Pehr K, Sasseville D. Connecting the dots in cutaneous T cell lymphoma (CTCL): STAT5 regulates malignant T cell proliferation via miR-155. Cell Cycle 2013; 12:2172-3; PMID:23803726; http://dx. doi.org/10.4161/cc.25550
    • (2013) Cell Cycle , vol.12 , pp. 2172-2173
    • Litvinov, I.V.1    Pehr, K.2    Sasseville, D.3
  • 16
    • 79953197948 scopus 로고    scopus 로고
    • Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer
    • PMID:21383199
    • Tili E, Michaille JJ, Wernicke D, Alder H, Costinean S, Volinia S, Croce CM. Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. ProcNat Acad Sci U S A 2011; 108: 4908-13; PMID:21383199; http://dx.doi.org/10.1073/pnas.1101795108
    • (2011) ProcNat Acad Sci U S A , vol.108 , pp. 4908-4913
    • Tili, E.1    Michaille, J.J.2    Wernicke, D.3    Alder, H.4    Costinean, S.5    Volinia, S.6    Croce, C.M.7
  • 19
    • 84886290618 scopus 로고    scopus 로고
    • Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma
    • PMID:23998443
    • Wong HK. Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma. Discov Med 2013; 16:71-8; PMID:23998443
    • (2013) Discov Med , vol.16 , pp. 71-78
    • Wong, H.K.1
  • 20
    • 33644814867 scopus 로고    scopus 로고
    • Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: Relevance to mechanism of therapeutic action
    • PMID:16297208
    • Zhang C, Richon V, Ni X, Talpur R, Duvic M. Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action. J Invest Dermatol 2005; 125:1045-52; PMID:16297208; http://dx.doi.org/10.1111/j.0022-202X.2005.23925.x
    • (2005) J Invest Dermatol , vol.125 , pp. 1045-1052
    • Zhang, C.1    Richon, V.2    Ni, X.3    Talpur, R.4    Duvic, M.5
  • 21
    • 77954475631 scopus 로고    scopus 로고
    • The role of histone deacetylase inhibitors in the treatment of patients with cutaneous T-cell lymphoma
    • Hymes KB. The role of histone deacetylase inhibitors in the treatment of patients with cutaneous T-cell lymphoma. Clin Lymphoma, Myeloma & Leukemia 2010; 10:98-109; http://dx.doi.org/10.3816/CLML.2010. n.014
    • (2010) Clin Lymphoma, Myeloma & Leukemia , vol.10 , pp. 98-109
    • Hymes, K.B.1
  • 22
    • 0242285719 scopus 로고    scopus 로고
    • STAT proteins: From normal control of cellular events to tumorigenesis
    • PMID:14502555
    • Calo V, Migliavacca M, Bazan V, Macaluso M, Buscemi M, Gebbia N, Russo A. STAT proteins: from normal control of cellular events to tumorigenesis. J Cell Physiol 2003; 197:157-68; PMID:14502555; http://dx.doi.org/10.1002/jcp.10364
    • (2003) J Cell Physiol , vol.197 , pp. 157-168
    • Calo, V.1    Migliavacca, M.2    Bazan, V.3    MacAluso, M.4    Buscemi, M.5    Gebbia, N.6    Russo, A.7
  • 23
    • 84855949597 scopus 로고    scopus 로고
    • Autocrine IL-21 stimulation is involved in the maintenance of constitutive STAT3 activation in Sezary syndrome
    • PMID:21938013
    • van der Fits L, Out-Luiting JJ, van Leeuwen MA, Samsom JN, Willemze R, Tensen CP, Vermeer MH. Autocrine IL-21 stimulation is involved in the maintenance of constitutive STAT3 activation in Sezary syndrome. J Invest Dermatol 2012; 132:440-7; PMID:21938013; http://dx.doi.org/10.1038/jid.2011.293
    • (2012) J Invest Dermatol , vol.132 , pp. 440-447
    • Van Der-Fits, L.1    Out-Luiting, J.J.2    Van Leeuwen, M.A.3    Samsom, J.N.4    Willemze, R.5    Tensen, C.P.6    Vermeer, M.H.7
  • 24
    • 0033052910 scopus 로고    scopus 로고
    • Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells
    • PMID:10374878
    • Nielsen M, Kaestel CG, Eriksen KW, Woetmann A, Stokkedal T, Kaltoft K, Geisler C, Röpke C, Odum N. Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells. Leukemia 1999; 13:735-8; PMID:10374878; http://dx.doi.org/10.1038/sj.leu.2401415
    • (1999) Leukemia , vol.13 , pp. 735-738
    • Nielsen, M.1    Kaestel, C.G.2    Eriksen, K.W.3    Woetmann, A.4    Stokkedal, T.5    Kaltoft, K.6    Geisler, C.7    Röpke, C.8    Odum, N.9
  • 26
    • 0035017383 scopus 로고    scopus 로고
    • Constitutive STAT3-activation in Sezary syndrome: Tyrphostin AG490 inhibits STAT3- activation, interleukin-2 receptor expression and growth of leukemic Sezary cells
    • PMID:11368440
    • Eriksen KW, Kaltoft K, Mikkelsen G, Nielsen M, Zhang Q, Geisler C, Nissen MH, Röpke C, Wasik MA, Odum N. Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3- activation, interleukin-2 receptor expression and growth of leukemic Sezary cells. Leukemia 2001; 15:787-93; PMID:11368440; http://dx.doi.org/10.1038/sj.leu.2402093
    • (2001) Leukemia , vol.15 , pp. 787-793
    • Eriksen, K.W.1    Kaltoft, K.2    Mikkelsen, G.3    Nielsen, M.4    Zhang, Q.5    Geisler, C.6    Nissen, M.H.7    Röpke, C.8    Wasik, M.A.9    Odum, N.10
  • 29
    • 84055184933 scopus 로고    scopus 로고
    • The role of cytokine signaling in the pathogenesis of cutaneous T-cell lymphoma
    • PMID:22236880
    • Abraham RM, Zhang Q, Odum N, Wasik MA. The role of cytokine signaling in the pathogenesis of cutaneous T-cell lymphoma. Cancer Biol Ther 2011; 12:1019-22; PMID:22236880; http://dx.doi.org/10.4161/cbt.12.12.18144
    • (2011) Cancer Biol Ther , vol.12 , pp. 1019-1022
    • Abraham, R.M.1    Zhang, Q.2    Odum, N.3    Wasik, M.A.4
  • 30
    • 13544261739 scopus 로고    scopus 로고
    • Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha
    • PMID:15618960
    • Brender C, Lovato P, Sommer VH, Woetmann A, Mathiesen AM, Geisler C, Wasik M, Ødum N. Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha. Leukemia 2005; 19:209-13; PMID:15618960; http://dx.doi.org/10.1038/sj.leu.2403610
    • (2005) Leukemia , vol.19 , pp. 209-213
    • Brender, C.1    Lovato, P.2    Sommer, V.H.3    Woetmann, A.4    Mathiesen, A.M.5    Geisler, C.6    Wasik, M.7    Ødum, N.8
  • 31
    • 0346367061 scopus 로고    scopus 로고
    • Interleukin-2 receptordirected therapies for cutaneous lymphomas
    • PMID:14710895
    • Foss FM, Waldmann TA. Interleukin-2 receptordirected therapies for cutaneous lymphomas. Hematol/Oncol Clin North Am 2003; 17:1449-58; PMID:14710895; http://dx.doi.org/10.1016/S0889-8588(03)00110-2
    • (2003) Hematol/Oncol Clin North Am , vol.17 , pp. 1449-1458
    • Foss, F.M.1    Waldmann, T.A.2
  • 32
    • 35948966315 scopus 로고    scopus 로고
    • STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression
    • PMID:17922009
    • Zhang Q, Wang HY, Liu X, Wasik MA. STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression. Nat Med 2007; 13:1341-8; PMID:17922009; http://dx.doi.org/10.1038/nm1659
    • (2007) Nat Med , vol.13 , pp. 1341-1348
    • Zhang, Q.1    Wang, H.Y.2    Liu, X.3    Wasik, M.A.4
  • 33
    • 0033520313 scopus 로고    scopus 로고
    • Cellular physiology of STAT3: Where's the cytoplasmic monomer?
    • PMID:10464281
    • Ndubuisi MI, Guo GG, Fried VA, Etlinger JD, Sehgal PB. Cellular physiology of STAT3: Where's the cytoplasmic monomer? J Biol Chem 1999; 274:25499-509; PMID:10464281; http://dx.doi.org/10.1074/jbc.274.36. 25499
    • (1999) J Biol Chem , vol.274 , pp. 25499-25509
    • Ndubuisi, M.I.1    Guo, G.G.2    Fried, V.A.3    Etlinger, J.D.4    Sehgal, P.B.5
  • 34
    • 2442459084 scopus 로고    scopus 로고
    • Plasma membrane rafts and chaperones in cytokine/STAT signaling
    • PMID:14515141
    • Sehgal PB. Plasma membrane rafts and chaperones in cytokine/STAT signaling. Acta Biochim Pol 2003; 50:583-94; PMID:14515141
    • (2003) Acta Biochim Pol , vol.50 , pp. 583-594
    • Sehgal, P.B.1
  • 37
    • 84904733767 scopus 로고    scopus 로고
    • Systematic review of tofacitinib: A new drug for the management of rheumatoid arthritis
    • PMID:25047498
    • Kaur K, Kalra S, Kaushal S. Systematic Review of Tofacitinib: A New Drug for the Management of Rheumatoid Arthritis. Clin Ther 2014; 36:1074-86; PMID:25047498; http://dx.doi.org/10.1016/j. clinthera.2014.06.018
    • (2014) Clin Ther , vol.36 , pp. 1074-1086
    • Kaur, K.1    Kalra, S.2    Kaushal, S.3


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