Intragenic DNA methylation prevents spurious transcription initiation

Nature

Volumn 543, Issue 7643, 2017, Pages 72-77

  Neri, Francesco ^a,b   Rapelli, Stefania ^c   Krepelova, Anna ^a,c   Incarnato, Danny ^a   Parlato, Caterina ^a   Basile, Giulia ^a   Maldotti, Mara ^a,c   Anselmi, Francesca ^a,c   Oliviero, Salvatore ^a,c  

^a Human Genetics Foundation   (Italy)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3B; HISTONE H3; RNA POLYMERASE II; CAPPED RNA; DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; MESSENGER RNA; SETD2 PROTEIN, MOUSE;

CANCER; CELLS AND CELL COMPONENTS; DNA; ENZYME ACTIVITY; FUNCTIONAL ROLE; GENE EXPRESSION; GENETIC ALGORITHM; METHYLATION; PROTEIN;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; EPIGENETICS; EXOSOME; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBOSOME; TRANSCRIPTION ELONGATION; TRANSCRIPTION INITIATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; DEFICIENCY; GENE; GENETIC EPIGENESIS; GENETICS; METABOLISM; MOUSE EMBRYONIC STEM CELL; NEOPLASM; POLYADENYLATION; RNA STABILITY; TRANSCRIPTION INITIATION SITE;

MAMMALIA;

ANIMALS; CELL LINE; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; GENES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; LYSINE; MICE; MOUSE EMBRYONIC STEM CELLS; NEOPLASMS; POLYADENYLATION; RIBOSOMES; RNA CAPS; RNA POLYMERASE II; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION INITIATION, GENETIC;

EID: 85014546354     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21373     Document Type: Article

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