MREdictor: A two-step dynamic interaction model that accounts for mRNA accessibility and Pumilio binding accurately predicts microRNA targets

Nucleic Acids Research

Volumn 41, Issue 18, 2013, Pages 8421-8433

  Incarnato, Danny ^a,b   Neri, Francesco ^a   Diamanti, Daniela ^c   Oliviero, Salvatore ^a,b  

^a Human Genetics Foundation   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c Siena Biotech SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; PUMILIO PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPUTER PROGRAM; CONTROLLED STUDY; GENE EXPRESSION; GENETIC ALGORITHM; MATHEMATICAL COMPUTING; MICRORNA RECOGNITION ELEMENT; PREDICTION; PRIORITY JOURNAL; PROTEIN RNA BINDING; PUMILIO RECOGNITION ELEMENT; RNA STRUCTURE; STRUCTURE ANALYSIS;

3' UNTRANSLATED REGIONS; ALGORITHMS; ANIMALS; BASE PAIRING; BINDING SITES; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MICE; MICRORNAS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RNA, MESSENGER; RNA-BINDING PROTEINS; THERMODYNAMICS;

EID: 84885945604     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt629     Document Type: Article

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