-
1
-
-
79955602230
-
Dengue: a continuing global threat
-
Guzman MG, Halstead SB, Artsob H, Buchy P, Farrar J, Gubler DJ, Hunsperger E, Kroeger A, Margolis HS, Martinez E, Nathan MB, Pelegrino JL, Simmons C, Yoksan S, Peeling RW. 2010. Dengue: a continuing global threat. Nat Rev Microbiol 8:S7-S16. https://doi.org/10.1038/nrmicro2460.
-
(2010)
Nat Rev Microbiol
, vol.8
, pp. S7-S16
-
-
Guzman, M.G.1
Halstead, S.B.2
Artsob, H.3
Buchy, P.4
Farrar, J.5
Gubler, D.J.6
Hunsperger, E.7
Kroeger, A.8
Margolis, H.S.9
Martinez, E.10
Nathan, M.B.11
Pelegrino, J.L.12
Simmons, C.13
Yoksan, S.14
Peeling, R.W.15
-
2
-
-
84872149525
-
Emerging infectious diseases in 2012: 20 years after the Institute of Medicine report
-
Morens DM, Fauci AS. 2012. Emerging infectious diseases in 2012: 20 years after the Institute of Medicine report. mBio 3:e00494-12. https://doi.org/10.1128/mBio.00494-12.
-
(2012)
MBio
, vol.3
-
-
Morens, D.M.1
Fauci, A.S.2
-
3
-
-
77951877953
-
Identification and functions of patternrecognition receptors
-
Kumagai Y, Akira S. 2010. Identification and functions of patternrecognition receptors. J Allergy Clin Immunol 125:985-992. https://doi.org/10.1016/j.jaci.2010.01.058.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 985-992
-
-
Kumagai, Y.1
Akira, S.2
-
4
-
-
65649141586
-
Pathogen recognition in the innate immune response
-
Kumar H, Kawai T, Akira S. 2009. Pathogen recognition in the innate immune response. Biochem J 420:1-16. https://doi.org/10.1042/BJ20090272.
-
(2009)
Biochem J
, vol.420
, pp. 1-16
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
5
-
-
84908279593
-
Activation and regulation of pathogen sensor RIG-I
-
Patel JR, Garcia-Sastre A. 2014. Activation and regulation of pathogen sensor RIG-I. Cytokine Growth Factor Rev 25:513-523. https://doi.org/10.1016/j.cytogfr.2014.08.005.
-
(2014)
Cytokine Growth Factor Rev
, vol.25
, pp. 513-523
-
-
Patel, J.R.1
Garcia-Sastre, A.2
-
6
-
-
79959649316
-
RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
-
Ramos HJ, Gale M, Jr. 2011. RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity. Curr Opin Virol 1:167-176. https://doi.org/10.1016/j.coviro.2011.04.004.
-
(2011)
Curr Opin Virol
, vol.1
, pp. 167-176
-
-
Ramos, H.J.1
Gale, M.2
-
7
-
-
32644456874
-
Antiviral innate immunity pathways
-
Seth RB, Sun L, Chen ZJ. 2006. Antiviral innate immunity pathways. Cell Res 16:141-147. https://doi.org/10.1038/sj.cr.7310019.
-
(2006)
Cell Res
, vol.16
, pp. 141-147
-
-
Seth, R.B.1
Sun, L.2
Chen, Z.J.3
-
8
-
-
84863115198
-
Intrinsic antiviral immunity
-
Yan N, Chen ZJ. 2012. Intrinsic antiviral immunity. Nat Immunol 13: 214-222. https://doi.org/10.1038/ni.2229.
-
(2012)
Nat Immunol
, vol.13
, pp. 214-222
-
-
Yan, N.1
Chen, Z.J.2
-
9
-
-
75749089555
-
Recognition of viral nucleic acids in innate immunity
-
Yoneyama M, Fujita T. 2010. Recognition of viral nucleic acids in innate immunity. Rev Med Virol 20:4-22. https://doi.org/10.1002/rmv.633.
-
(2010)
Rev Med Virol
, vol.20
, pp. 4-22
-
-
Yoneyama, M.1
Fujita, T.2
-
10
-
-
36749069393
-
Interferons at age 50: past, current and future impact on biomedicine
-
Borden EC, Sen GC, Uze G, Silverman RH, Ransohoff RM, Foster GR, Stark GR. 2007. Interferons at age 50: past, current and future impact on biomedicine. Nat Rev Drug Discov 6:975-990. https://doi.org/10.1038/nrd2422.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 975-990
-
-
Borden, E.C.1
Sen, G.C.2
Uze, G.3
Silverman, R.H.4
Ransohoff, R.M.5
Foster, G.R.6
Stark, G.R.7
-
11
-
-
33646555810
-
Type 1 interferons and the virus-host relationship: a lesson in detente
-
Garcia-Sastre A, Biron CA. 2006. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312:879-882. https://doi.org/10.1126/science.1125676.
-
(2006)
Science
, vol.312
, pp. 879-882
-
-
Garcia-Sastre, A.1
Biron, C.A.2
-
12
-
-
82955187705
-
Interferon-stimulated genes and their antiviral effector functions
-
Schoggins JW, Rice CM. 2011. Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 1:519-525. https://doi.org/10.1016/j.coviro.2011.10.008.
-
(2011)
Curr Opin Virol
, vol.1
, pp. 519-525
-
-
Schoggins, J.W.1
Rice, C.M.2
-
13
-
-
33748455338
-
Type I interferons in host defense
-
Stetson DB, Medzhitov R. 2006. Type I interferons in host defense. Immunity 25:373-381. https://doi.org/10.1016/j.immuni.2006.08.007.
-
(2006)
Immunity
, vol.25
, pp. 373-381
-
-
Stetson, D.B.1
Medzhitov, R.2
-
14
-
-
75749140581
-
RIG-I detects viral genomic RNA during negative-strand RNA virus infection
-
Rehwinkel J, Tan CP, Goubau D, Schulz O, Pichlmair A, Bier K, Robb N, Vreede F, Barclay W, Fodor E, Reis e Sousa C. 2010. RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 140: 397-408. https://doi.org/10.1016/j.cell.2010.01.020.
-
(2010)
Cell
, vol.140
, pp. 397-408
-
-
Rehwinkel, J.1
Tan, C.P.2
Goubau, D.3
Schulz, O.4
Pichlmair, A.5
Bier, K.6
Robb, N.7
Vreede, F.8
Barclay, W.9
Fodor, E.10
Reis e Sousa, C.11
-
15
-
-
39149107423
-
MDA5/RIG-I and virus recognition
-
Takeuchi O, Akira S. 2008. MDA5/RIG-I and virus recognition. Curr Opin Immunol 20:17-22. https://doi.org/10.1016/j.coi.2008.01.002.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 17-22
-
-
Takeuchi, O.1
Akira, S.2
-
16
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5:730-737. https://doi.org/10.1038/ni1087.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
17
-
-
77952503750
-
Peroxisomes are signaling platforms for antiviral innate immunity
-
Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC. 2010. Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141:668-681. https://doi.org/10.1016/j.cell.2010.04.018.
-
(2010)
Cell
, vol.141
, pp. 668-681
-
-
Dixit, E.1
Boulant, S.2
Zhang, Y.3
Lee, A.S.4
Odendall, C.5
Shum, B.6
Hacohen, N.7
Chen, Z.J.8
Whelan, S.P.9
Fransen, M.10
Nibert, M.L.11
Superti-Furga, G.12
Kagan, J.C.13
-
18
-
-
80052281413
-
Mitochondrialassociated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus
-
Horner SM, Liu HM, Park HS, Briley J, Gale M, Jr. 2011. Mitochondrialassociated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc Natl Acad Sci U S A 108:14590-14595. https://doi.org/10.1073/pnas.1110133108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 14590-14595
-
-
Horner, S.M.1
Liu, H.M.2
Park, H.S.3
Briley, J.4
Gale, M.5
-
19
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S. 2005. IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction. Nat Immunol 6:981-988. https://doi.org/10.1038/ni1243.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
Kato, H.6
Ishii, K.J.7
Takeuchi, O.8
Akira, S.9
-
20
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J. 2005. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437:1167-1172. https://doi.org/10.1038/nature04193.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
Tschopp, J.7
-
21
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkappaB and IRF 3. Cell 122:669-682. https://doi.org/10.1016/j.cell.2005.08.012.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
22
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. 2005. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell 19: 727-740. https://doi.org/10.1016/j.molcel.2005.08.014.
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
Shu, H.B.6
-
23
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ. 2011. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 146:448-461. https://doi.org/10.1016/j.cell.2011.06.041.
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
24
-
-
84898747432
-
Structural basis for the prion-like MAVS filaments in antiviral innate immunity
-
Xu H, He X, Zheng H, Huang LJ, Hou F, Yu Z, de la Cruz MJ, Borkowski B, Zhang X, Chen ZJ, Jiang QX. 2014. Structural basis for the prion-like MAVS filaments in antiviral innate immunity. eLife 3:e01489. https://doi.org/10.7554/eLife.01489.
-
(2014)
ELife
, vol.3
-
-
Xu, H.1
He, X.2
Zheng, H.3
Huang, L.J.4
Hou, F.5
Yu, Z.6
de la Cruz, M.J.7
Borkowski, B.8
Zhang, X.9
Chen, Z.J.10
Jiang, Q.X.11
-
25
-
-
0038393016
-
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. 2003. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4:491-496.
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
26
-
-
34548129605
-
Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response
-
Hiscott J. 2007. Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response. Cytokine Growth Factor Rev 18:483-490. https://doi.org/10.1016/j.cytogfr.2007.06.002.
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, pp. 483-490
-
-
Hiscott, J.1
-
27
-
-
0032954248
-
Triggering the interferon response: the role of IRF-3 transcription factor
-
Hiscott J, Pitha P, Genin P, Nguyen H, Heylbroeck C, Mamane Y, Algarte M, Lin R. 1999. Triggering the interferon response: the role of IRF-3 transcription factor. J Interferon Cytokine Res 19:1-13. https://doi.org/10.1089/107999099314360.
-
(1999)
J Interferon Cytokine Res
, vol.19
, pp. 1-13
-
-
Hiscott, J.1
Pitha, P.2
Genin, P.3
Nguyen, H.4
Heylbroeck, C.5
Mamane, Y.6
Algarte, M.7
Lin, R.8
-
28
-
-
0036710523
-
Multiple signaling pathways leading to the activation of interferon regulatory factor 3
-
Servant MJ, Grandvaux N, Hiscott J. 2002. Multiple signaling pathways leading to the activation of interferon regulatory factor 3. Biochem Pharmacol 64:985-992. https://doi.org/10.1016/S0006-2952(02)01165-6.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 985-992
-
-
Servant, M.J.1
Grandvaux, N.2
Hiscott, J.3
-
29
-
-
0031893220
-
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
-
Lin R, Heylbroeck C, Pitha PM, Hiscott J. 1998. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol Cell Biol 18:2986-2996. https://doi.org/10.1128/MCB.18.5.2986.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2986-2996
-
-
Lin, R.1
Heylbroeck, C.2
Pitha, P.M.3
Hiscott, J.4
-
30
-
-
0032915860
-
Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains
-
Lin R, Mamane Y, Hiscott J. 1999. Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains. Mol Cell Biol 19:2465-2474. https://doi.org/10.1128/MCB.19.4.2465.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2465-2474
-
-
Lin, R.1
Mamane, Y.2
Hiscott, J.3
-
31
-
-
34547930163
-
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch
-
Panne D, McWhirter SM, Maniatis T, Harrison SC. 2007. Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. J Biol Chem 282:22816-22822. https://doi.org/10.1074/jbc.M703019200.
-
(2007)
J Biol Chem
, vol.282
, pp. 22816-22822
-
-
Panne, D.1
McWhirter, S.M.2
Maniatis, T.3
Harrison, S.C.4
-
32
-
-
0033858399
-
Analyses of virus-induced homomeric and heteromeric protein associations between IRF-3 and coactivator CBP/p300
-
Suhara W, Yoneyama M, Iwamura T, Yoshimura S, Tamura K, Namiki H, Aimoto S, Fujita T. 2000. Analyses of virus-induced homomeric and heteromeric protein associations between IRF-3 and coactivator CBP/p300. J Biochem 128:301-307. https://doi.org/10.1093/oxfordjournals.jbchem.a022753.
-
(2000)
J Biochem
, vol.128
, pp. 301-307
-
-
Suhara, W.1
Yoneyama, M.2
Iwamura, T.3
Yoshimura, S.4
Tamura, K.5
Namiki, H.6
Aimoto, S.7
Fujita, T.8
-
33
-
-
77954714807
-
Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change
-
Takahasi K, Horiuchi M, Fujii K, Nakamura S, Noda NN, Yoneyama M, Fujita T, Inagaki F. 2010. Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change. Genes Cells 15:901-910. https://doi.org/10.1111/j.1365-2443.2010.01427.x.
-
(2010)
Genes Cells
, vol.15
, pp. 901-910
-
-
Takahasi, K.1
Horiuchi, M.2
Fujii, K.3
Nakamura, S.4
Noda, N.N.5
Yoneyama, M.6
Fujita, T.7
Inagaki, F.8
-
34
-
-
0032015647
-
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
-
Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, Maniatis T. 1998. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell 1:507-518. https://doi.org/10.1016/S1097-2765(00)80051-9.
-
(1998)
Mol Cell
, vol.1
, pp. 507-518
-
-
Wathelet, M.G.1
Lin, C.H.2
Parekh, B.S.3
Ronco, L.V.4
Howley, P.M.5
Maniatis, T.6
-
35
-
-
84887990870
-
Mechanisms of MAVS regulation at the mitochondrial membrane
-
Jacobs JL, Coyne CB. 2013. Mechanisms of MAVS regulation at the mitochondrial membrane. J Mol Biol 425:5009-5019. https://doi.org/10.1016/j.jmb.2013.10.007.
-
(2013)
J Mol Biol
, vol.425
, pp. 5009-5019
-
-
Jacobs, J.L.1
Coyne, C.B.2
-
36
-
-
84882705934
-
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
-
Liu S, Chen J, Cai X, Wu J, Chen X, Wu YT, Sun L, Chen ZJ. 2013. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. eLife 2:e00785. https://doi.org/10.7554/eLife.00785.
-
(2013)
ELife
, vol.2
-
-
Liu, S.1
Chen, J.2
Cai, X.3
Wu, J.4
Chen, X.5
Wu, Y.T.6
Sun, L.7
Chen, Z.J.8
-
37
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa H, Barber GN. 2008. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455:674-678. https://doi.org/10.1038/nature07317.
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
38
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun L, Wu J, Du F, Chen X, Chen ZJ. 2013. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339:786-791. https://doi.org/10.1126/science.1232458.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
39
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB. 2008. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 29:538-550. https://doi.org/10.1016/j.immuni.2008.09.003.
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
Yang, Y.2
Li, S.3
Wang, Y.Y.4
Li, Y.5
Diao, F.6
Lei, C.7
He, X.8
Zhang, L.9
Tien, P.10
Shu, H.B.11
-
40
-
-
80052675864
-
IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1
-
Liu XY, Chen W, Wei B, Shan YF, Wang C. 2011. IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1. J Immunol 187:2559-2568. https://doi.org/10.4049/jimmunol.1100963.
-
(2011)
J Immunol
, vol.187
, pp. 2559-2568
-
-
Liu, X.Y.1
Chen, W.2
Wei, B.3
Shan, Y.F.4
Wang, C.5
-
41
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU. 2007. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 446:916-920. https://doi.org/10.1038/nature05732.
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
Shin, Y.C.2
Joo, C.H.3
Urano, T.4
Liang, C.5
Sun, L.6
Takeuchi, O.7
Akira, S.8
Chen, Z.9
Inoue, S.10
Jung, J.U.11
-
42
-
-
73549097331
-
The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation
-
Nakhaei P, Mesplede T, Solis M, Sun Q, Zhao T, Yang L, Chuang TH, Ware CF, Lin R, Hiscott J. 2009. The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation. PLoS Pathog 5:e1000650. https://doi.org/10.1371/journal.ppat.1000650.
-
(2009)
PLoS Pathog
, vol.5
-
-
Nakhaei, P.1
Mesplede, T.2
Solis, M.3
Sun, Q.4
Zhao, T.5
Yang, L.6
Chuang, T.H.7
Ware, C.F.8
Lin, R.9
Hiscott, J.10
-
43
-
-
78650189572
-
The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection
-
Oshiumi H, Miyashita M, Inoue N, Okabe M, Matsumoto M, Seya T. 2010. The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection. Cell Host Microbe 8:496-509. https://doi.org/10.1016/j.chom.2010.11.008.
-
(2010)
Cell Host Microbe
, vol.8
, pp. 496-509
-
-
Oshiumi, H.1
Miyashita, M.2
Inoue, N.3
Okabe, M.4
Matsumoto, M.5
Seya, T.6
-
44
-
-
70350004240
-
Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3
-
Zeng W, Xu M, Liu S, Sun L, Chen ZJ. 2009. Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol Cell 36:315-325. https://doi.org/10.1016/j.molcel.2009.09.037.
-
(2009)
Mol Cell
, vol.36
, pp. 315-325
-
-
Zeng, W.1
Xu, M.2
Liu, S.3
Sun, L.4
Chen, Z.J.5
-
45
-
-
34249058119
-
The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways
-
Zhao T, Yang L, Sun Q, Arguello M, Ballard DW, Hiscott J, Lin R. 2007. The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol 8:592-600. https://doi.org/10.1038/ni1465.
-
(2007)
Nat Immunol
, vol.8
, pp. 592-600
-
-
Zhao, T.1
Yang, L.2
Sun, Q.3
Arguello, M.4
Ballard, D.W.5
Hiscott, J.6
Lin, R.7
-
46
-
-
80053131464
-
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
-
Li S, Wang L, Berman M, Kong YY, Dorf ME. 2011. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity 35:426-440. https://doi.org/10.1016/j.immuni.2011.06.014.
-
(2011)
Immunity
, vol.35
, pp. 426-440
-
-
Li, S.1
Wang, L.2
Berman, M.3
Kong, Y.Y.4
Dorf, M.E.5
-
47
-
-
77951247349
-
Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response
-
Mao AP, Li S, Zhong B, Li Y, Yan J, Li Q, Teng C, Shu HB. 2010. Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response. J Biol Chem 285:9470-9476. https://doi.org/10.1074/jbc.M109.071043.
-
(2010)
J Biol Chem
, vol.285
, pp. 9470-9476
-
-
Mao, A.P.1
Li, S.2
Zhong, B.3
Li, Y.4
Yan, J.5
Li, Q.6
Teng, C.7
Shu, H.B.8
-
48
-
-
33746479050
-
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
-
Saha SK, Pietras EM, He JQ, Kang JR, Liu SY, Oganesyan G, Shahangian A, Zarnegar B, Shiba TL, Wang Y, Cheng G. 2006. Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. EMBO J 25:3257-3263. https://doi.org/10.1038/sj.emboj.7601220.
-
(2006)
EMBO J
, vol.25
, pp. 3257-3263
-
-
Saha, S.K.1
Pietras, E.M.2
He, J.Q.3
Kang, J.R.4
Liu, S.Y.5
Oganesyan, G.6
Shahangian, A.7
Zarnegar, B.8
Shiba, T.L.9
Wang, Y.10
Cheng, G.11
-
49
-
-
77949427242
-
TRAF5 is a downstream target of MAVS in antiviral innate immune signaling
-
Tang ED, Wang CY. 2010. TRAF5 is a downstream target of MAVS in antiviral innate immune signaling. PLoS One 5:e9172. https://doi.org/10.1371/journal.pone.0009172.
-
(2010)
PLoS One
, vol.5
-
-
Tang, E.D.1
Wang, C.Y.2
-
50
-
-
84892606477
-
TRIM14 is a mitochondrial adaptor that facilitates retinoic acidinducible gene-I-like receptor-mediated innate immune response
-
Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, Jiang Z, He B, Jin Q, Wang J. 2014. TRIM14 is a mitochondrial adaptor that facilitates retinoic acidinducible gene-I-like receptor-mediated innate immune response. Proc Natl Acad Sci U S A 111:E245-E254. https://doi.org/10.1073/pnas.1316941111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E245-E254
-
-
Zhou, Z.1
Jia, X.2
Xue, Q.3
Dou, Z.4
Ma, Y.5
Zhao, Z.6
Jiang, Z.7
He, B.8
Jin, Q.9
Wang, J.10
-
51
-
-
35748942913
-
Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF
-
Gatot JS, Gioia R, Chau TL, Patrascu F, Warnier M, Close P, Chapelle JP, Muraille E, Brown K, Siebenlist U, Piette J, Dejardin E, Chariot A. 2007. Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. J Biol Chem 282:31131-31146. https://doi.org/10.1074/jbc.M701690200.
-
(2007)
J Biol Chem
, vol.282
, pp. 31131-31146
-
-
Gatot, J.S.1
Gioia, R.2
Chau, T.L.3
Patrascu, F.4
Warnier, M.5
Close, P.6
Chapelle, J.P.7
Muraille, E.8
Brown, K.9
Siebenlist, U.10
Piette, J.11
Dejardin, E.12
Chariot, A.13
-
52
-
-
34249058290
-
Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
-
Guo B, Cheng G. 2007. Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J Biol Chem 282:11817-11826. https://doi.org/10.1074/jbc.M700017200.
-
(2007)
J Biol Chem
, vol.282
, pp. 11817-11826
-
-
Guo, B.1
Cheng, G.2
-
53
-
-
69049086481
-
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
-
Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T, Akira S. 2009. TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 10:965-972. https://doi.org/10.1038/ni.1771.
-
(2009)
Nat Immunol
, vol.10
, pp. 965-972
-
-
Kawagoe, T.1
Takeuchi, O.2
Takabatake, Y.3
Kato, H.4
Isaka, Y.5
Tsujimura, T.6
Akira, S.7
-
54
-
-
77956304154
-
Tom70 mediates activation of interferon regulatory factor 3 on mitochondria
-
Liu XY, Wei B, Shi HX, Shan YF, Wang C. 2010. Tom70 mediates activation of interferon regulatory factor 3 on mitochondria. Cell Res 20:994-1011. https://doi.org/10.1038/cr.2010.103.
-
(2010)
Cell Res
, vol.20
, pp. 994-1011
-
-
Liu, X.Y.1
Wei, B.2
Shi, H.X.3
Shan, Y.F.4
Wang, C.5
-
55
-
-
84924778328
-
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
-
Liu S, Cai X, Wu J, Cong Q, Chen X, Li T, Du F, Ren J, Wu YT, Grishin NV, Chen ZJ. 2015. Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation. Science 347:aaa2630. https://doi.org/10.1126/science.aaa2630.
-
(2015)
Science
, vol.347
-
-
Liu, S.1
Cai, X.2
Wu, J.3
Cong, Q.4
Chen, X.5
Li, T.6
Du, F.7
Ren, J.8
Wu, Y.T.9
Grishin, N.V.10
Chen, Z.J.11
-
56
-
-
41549165085
-
Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?
-
Chau TL, Gioia R, Gatot JS, Patrascu F, Carpentier I, Chapelle JP, O'Neill L, Beyaert R, Piette J, Chariot A. 2008. Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated? Trends Biochem Sci 33: 171-180. https://doi.org/10.1016/j.tibs.2008.01.002.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 171-180
-
-
Chau, T.L.1
Gioia, R.2
Gatot, J.S.3
Patrascu, F.4
Carpentier, I.5
Chapelle, J.P.6
O'Neill, L.7
Beyaert, R.8
Piette, J.9
Chariot, A.10
-
57
-
-
10744221904
-
Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling
-
Fujita F, Taniguchi Y, Kato T, Narita Y, Furuya A, Ogawa T, Sakurai H, Joh T, Itoh M, Delhase M, Karin M, Nakanishi M. 2003. Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling. Mol Cell Biol 23:7780-7793. https://doi.org/10.1128/MCB.23.21.7780-7793.2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7780-7793
-
-
Fujita, F.1
Taniguchi, Y.2
Kato, T.3
Narita, Y.4
Furuya, A.5
Ogawa, T.6
Sakurai, H.7
Joh, T.8
Itoh, M.9
Delhase, M.10
Karin, M.11
Nakanishi, M.12
-
58
-
-
34447342317
-
SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK
-
Ryzhakov G, Randow F. 2007. SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. EMBO J 26:3180-3190. https://doi.org/10.1038/sj.emboj.7601743.
-
(2007)
EMBO J
, vol.26
, pp. 3180-3190
-
-
Ryzhakov, G.1
Randow, F.2
-
59
-
-
10844219793
-
Cutting edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation
-
Sasai M, Oshiumi H, Matsumoto M, Inoue N, Fujita F, Nakanishi M, Seya T. 2005. Cutting edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation. J Immunol 174: 27-30. https://doi.org/10.4049/jimmunol.174.1.27.
-
(2005)
J Immunol
, vol.174
, pp. 27-30
-
-
Sasai, M.1
Oshiumi, H.2
Matsumoto, M.3
Inoue, N.4
Fujita, F.5
Nakanishi, M.6
Seya, T.7
-
60
-
-
33845416390
-
NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction
-
Sasai M, Shingai M, Funami K, Yoneyama M, Fujita T, Matsumoto M, Seya T. 2006. NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction. J Immunol 177: 8676-8683. https://doi.org/10.4049/jimmunol.177.12.8676.
-
(2006)
J Immunol
, vol.177
, pp. 8676-8683
-
-
Sasai, M.1
Shingai, M.2
Funami, K.3
Yoneyama, M.4
Fujita, T.5
Matsumoto, M.6
Seya, T.7
-
61
-
-
84897675720
-
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in type-I interferon response
-
Pulloor NK, Nair S, Kostic AD, Bist P, Weaver JD, Riley AM, Tyagi R, Uchil PD, York JD, Snyder SH, Garcia-Sastre A, Potter BV, Lin R, Shears SB, Xavier RJ, Krishnan MN. 2014. Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in type-I interferon response. PLoS Pathog 10:e1003981. https://doi.org/10.1371/journal.ppat.1003981.
-
(2014)
PLoS Pathog
, vol.10
-
-
Pulloor, N.K.1
Nair, S.2
Kostic, A.D.3
Bist, P.4
Weaver, J.D.5
Riley, A.M.6
Tyagi, R.7
Uchil, P.D.8
York, J.D.9
Snyder, S.H.10
Garcia-Sastre, A.11
Potter, B.V.12
Lin, R.13
Shears, S.B.14
Xavier, R.J.15
Krishnan, M.N.16
-
62
-
-
77649314475
-
Expanding the substantial interactome of NEMO using protein microarrays
-
Fenner BJ, Scannell M, Prehn JH. 2010. Expanding the substantial interactome of NEMO using protein microarrays. PLoS One 5:e8799. https://doi.org/10.1371/journal.pone.0008799.
-
(2010)
PLoS One
, vol.5
-
-
Fenner, B.J.1
Scannell, M.2
Prehn, J.H.3
-
63
-
-
84872856989
-
Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus-and dsRNA-stimulated human lung epithelial cells
-
Li Y, Xie J, Wu S, Xia J, Zhang P, Liu C, Zhang P, Huang X. 2013. Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus-and dsRNA-stimulated human lung epithelial cells. PLoS One 8:e55108. https://doi.org/10.1371/journal.pone.0055108.
-
(2013)
PLoS One
, vol.8
-
-
Li, Y.1
Xie, J.2
Wu, S.3
Xia, J.4
Zhang, P.5
Liu, C.6
Zhang, P.7
Huang, X.8
-
64
-
-
0346457016
-
Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1, 3, 4, 5-P4-/PtdIns 3, 4, 5-P3-binding, adapter proteins
-
Hanck T, Stricker R, Sedehizade F, Reiser G. 2004. Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1, 3, 4, 5-P4-/PtdIns 3, 4, 5-P3-binding, adapter proteins. J Neurochem 88:326-336.
-
(2004)
J Neurochem
, vol.88
, pp. 326-336
-
-
Hanck, T.1
Stricker, R.2
Sedehizade, F.3
Reiser, G.4
-
65
-
-
52249093973
-
Consensus nomenclature for the human ArfGAP domain-containing proteins
-
Kahn RA, Bruford E, Inoue H, Logsdon JM, Jr, Nie Z, Premont RT, Randazzo PA, Satake M, Theibert AB, Zapp ML, Cassel D. 2008. Consensus nomenclature for the human ArfGAP domain-containing proteins. J Cell Biol 182:1039-1044. https://doi.org/10.1083/jcb.200806041.
-
(2008)
J Cell Biol
, vol.182
, pp. 1039-1044
-
-
Kahn, R.A.1
Bruford, E.2
Inoue, H.3
Logsdon, J.M.4
Nie, Z.5
Premont, R.T.6
Randazzo, P.A.7
Satake, M.8
Theibert, A.B.9
Zapp, M.L.10
Cassel, D.11
-
66
-
-
0036011165
-
Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle
-
Whitley P, Gibbard AM, Koumanov F, Oldfield S, Kilgour EE, Prestwich GD, Holman GD. 2002. Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle. Eur J Cell Biol 81:222-230. https://doi.org/10.1078/0171-9335-00242.
-
(2002)
Eur J Cell Biol
, vol.81
, pp. 222-230
-
-
Whitley, P.1
Gibbard, A.M.2
Koumanov, F.3
Oldfield, S.4
Kilgour, E.E.5
Prestwich, G.D.6
Holman, G.D.7
-
67
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K, Uematsu S, Jung A, Kawai T, Ishii KJ, Yamaguchi O, Otsu K, Tsujimura T, Koh CS, Reis e Sousa C, Matsuura Y, Fujita T, Akira S. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441:101-105. https://doi.org/10.1038/nature04734.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
Matsui, K.6
Uematsu, S.7
Jung, A.8
Kawai, T.9
Ishii, K.J.10
Yamaguchi, O.11
Otsu, K.12
Tsujimura, T.13
Koh, C.S.14
Reis e Sousa, C.15
Matsuura, Y.16
Fujita, T.17
Akira, S.18
-
68
-
-
35148814898
-
Arf GAPs as regulators of the actin cytoskeleton
-
Randazzo PA, Inoue H, Bharti S. 2007. Arf GAPs as regulators of the actin cytoskeleton. Biol Cell 99:583-600. https://doi.org/10.1042/BC20070034.
-
(2007)
Biol Cell
, vol.99
, pp. 583-600
-
-
Randazzo, P.A.1
Inoue, H.2
Bharti, S.3
-
69
-
-
33845975666
-
Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1-and 2-dependent NF-kappaB activation
-
Yamamoto-Furusho JK, Barnich N, Xavier R, Hisamatsu T, Podolsky DK. 2006. Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1-and 2-dependent NF-kappaB activation. J Biol Chem 281:36060-36070. https://doi.org/10.1074/jbc.M602383200.
-
(2006)
J Biol Chem
, vol.281
, pp. 36060-36070
-
-
Yamamoto-Furusho, J.K.1
Barnich, N.2
Xavier, R.3
Hisamatsu, T.4
Podolsky, D.K.5
-
70
-
-
84902650399
-
ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome
-
Venturin M, Carra S, Gaudenzi G, Brunelli S, Gallo GR, Moncini S, Cotelli F, Riva P. 2014. ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome. J Med Genet 51:436-443. https://doi.org/10.1136/jmedgenet-2013-102240.
-
(2014)
J Med Genet
, vol.51
, pp. 436-443
-
-
Venturin, M.1
Carra, S.2
Gaudenzi, G.3
Brunelli, S.4
Gallo, G.R.5
Moncini, S.6
Cotelli, F.7
Riva, P.8
-
71
-
-
84871441279
-
Centaurin-alpha(2) interacts with beta-tubulin and stabilizes microtubules
-
Zuccotti P, Cartelli D, Stroppi M, Pandini V, Venturin M, Aliverti A, Battaglioli E, Cappelletti G, Riva P. 2012. Centaurin-alpha(2) interacts with beta-tubulin and stabilizes microtubules. PLoS One 7:e52867. https://doi.org/10.1371/journal.pone.0052867.
-
(2012)
PLoS One
, vol.7
-
-
Zuccotti, P.1
Cartelli, D.2
Stroppi, M.3
Pandini, V.4
Venturin, M.5
Aliverti, A.6
Battaglioli, E.7
Cappelletti, G.8
Riva, P.9
-
72
-
-
79960049196
-
A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response
-
Paz S, Vilasco M, Werden SJ, Arguello M, Joseph-Pillai D, Zhao T, Nguyen TL, Sun Q, Meurs EF, Lin R, Hiscott J. 2011. A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response. Cell Res 21:895-910. https://doi.org/10.1038/cr.2011.2.
-
(2011)
Cell Res
, vol.21
, pp. 895-910
-
-
Paz, S.1
Vilasco, M.2
Werden, S.J.3
Arguello, M.4
Joseph-Pillai, D.5
Zhao, T.6
Nguyen, T.L.7
Sun, Q.8
Meurs, E.F.9
Lin, R.10
Hiscott, J.11
-
73
-
-
34547188530
-
Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes
-
Ikeda F, Hecker CM, Rozenknop A, Nordmeier RD, Rogov V, Hofmann K, Akira S, Dotsch V, Dikic I. 2007. Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes. EMBO J 26:3451-3462. https://doi.org/10.1038/sj.emboj.7601773.
-
(2007)
EMBO J
, vol.26
, pp. 3451-3462
-
-
Ikeda, F.1
Hecker, C.M.2
Rozenknop, A.3
Nordmeier, R.D.4
Rogov, V.5
Hofmann, K.6
Akira, S.7
Dotsch, V.8
Dikic, I.9
-
74
-
-
84866484016
-
NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses
-
Wang L, Li S, Dorf ME. 2012. NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses. PLoS One 7:e43756. https://doi.org/10.1371/journal.pone.0043756.
-
(2012)
PLoS One
, vol.7
-
-
Wang, L.1
Li, S.2
Dorf, M.E.3
|