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Volumn 7, Issue 9, 2012, Pages

NEMO Binds Ubiquitinated TANK-Binding Kinase 1 (TBK1) to Regulate Innate Immune Responses to RNA Viruses

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ENZYME; I KAPPA B KINASE GAMMA; INTERFERON; MITOCHONDRIAL PROTEIN; TANK BINDING KINASE 1; TRANSCRIPTION FACTOR; UBIQUITIN; UNCLASSIFIED DRUG; VIRUS RNA;

EID: 84866484016     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043756     Document Type: Article
Times cited : (50)

References (40)
  • 1
    • 80052184362 scopus 로고    scopus 로고
    • Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity
    • Kawasaki T, Kawai T, Akira S, (2011) Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity. Immunol Rev 243: 61-73.
    • (2011) Immunol Rev , vol.243 , pp. 61-73
    • Kawasaki, T.1    Kawai, T.2    Akira, S.3
  • 2
    • 77955415407 scopus 로고    scopus 로고
    • Activation of host pattern recognition receptors by viruses
    • Brennan K, Bowie AG, (2010) Activation of host pattern recognition receptors by viruses. Curr Opin Microbiol 13: 503-507.
    • (2010) Curr Opin Microbiol , vol.13 , pp. 503-507
    • Brennan, K.1    Bowie, A.G.2
  • 3
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, et al. (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300: 1148-1151.
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    tenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5
  • 4
    • 0038393016 scopus 로고    scopus 로고
    • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
    • Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, et al. (2003) IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4: 491-496.
    • (2003) Nat Immunol , vol.4 , pp. 491-496
    • Fitzgerald, K.A.1    McWhirter, S.M.2    Faia, K.L.3    Rowe, D.C.4    Latz, E.5
  • 5
    • 4344566281 scopus 로고    scopus 로고
    • The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection
    • Hemmi H, Takeuchi O, Sato S, Yamamoto M, Kaisho T, et al. (2004) The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J Exp Med 199: 1641-1650.
    • (2004) J Exp Med , vol.199 , pp. 1641-1650
    • Hemmi, H.1    Takeuchi, O.2    Sato, S.3    Yamamoto, M.4    Kaisho, T.5
  • 6
    • 0345827590 scopus 로고    scopus 로고
    • IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
    • McWhirter SM, Fitzgerald KA, Rosains J, Rowe DC, Golenbock DT, et al. (2004) IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc Natl Acad Sci U S A 101: 233-238.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 233-238
    • McWhirter, S.M.1    Fitzgerald, K.A.2    Rosains, J.3    Rowe, D.C.4    Golenbock, D.T.5
  • 7
    • 26444475464 scopus 로고    scopus 로고
    • Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1
    • Unterstab G, Ludwig S, Anton A, Planz O, Dauber B, et al. (2005) Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1. Proc Natl Acad Sci U S A 102: 13640-13645.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13640-13645
    • Unterstab, G.1    Ludwig, S.2    Anton, A.3    Planz, O.4    Dauber, B.5
  • 8
    • 50949085475 scopus 로고    scopus 로고
    • The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation
    • Alff PJ, Sen N, Gorbunova E, Gavrilovskaya IN, Mackow ER, (2008) The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation. J Virol 82: 9115-9122.
    • (2008) J Virol , vol.82 , pp. 9115-9122
    • Alff, P.J.1    Sen, N.2    Gorbunova, E.3    Gavrilovskaya, I.N.4    Mackow, E.R.5
  • 9
    • 84863127174 scopus 로고    scopus 로고
    • Inhibition of TANK binding kinase 1 by herpes simplex virus 1 facilitates productive infection
    • Ma Y, Jin H, Valyi-Nagy T, Cao Y, Yan Z, et al. (2012) Inhibition of TANK binding kinase 1 by herpes simplex virus 1 facilitates productive infection. J Virol 86: 2188-2196.
    • (2012) J Virol , vol.86 , pp. 2188-2196
    • Ma, Y.1    Jin, H.2    Valyi-Nagy, T.3    Cao, Y.4    Yan, Z.5
  • 10
    • 17844395681 scopus 로고    scopus 로고
    • Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses
    • Otsuka M, Kato N, Moriyama M, Taniguchi H, Wang Y, et al. (2005) Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses. Hepatology 41: 1004-1012.
    • (2005) Hepatology , vol.41 , pp. 1004-1012
    • Otsuka, M.1    Kato, N.2    Moriyama, M.3    Taniguchi, H.4    Wang, Y.5
  • 11
    • 51049106824 scopus 로고    scopus 로고
    • The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response
    • Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cardenas WB, et al. (2008) The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep 9: 930-936.
    • (2008) EMBO Rep , vol.9 , pp. 930-936
    • Friedman, C.S.1    O'Donnell, M.A.2    Legarda-Addison, D.3    Ng, A.4    Cardenas, W.B.5
  • 12
    • 67649229630 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon
    • Wang C, Chen T, Zhang J, Yang M, Li N, et al. (2009) The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol 10: 744-752.
    • (2009) Nat Immunol , vol.10 , pp. 744-752
    • Wang, C.1    Chen, T.2    Zhang, J.3    Yang, M.4    Li, N.5
  • 13
    • 80755126865 scopus 로고    scopus 로고
    • Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
    • Li S, Wang L, Berman M, Kong YY, Dorf ME, (2011) Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity 35: 426-440.
    • (2011) Immunity , vol.35 , pp. 426-440
    • Li, S.1    Wang, L.2    Berman, M.3    Kong, Y.Y.4    Dorf, M.E.5
  • 14
    • 43249100317 scopus 로고    scopus 로고
    • An obligatory role of mind bomb-1 in notch signaling of mammalian development
    • Koo BK, Yoon MJ, Yoon KJ, Im SK, Kim YY, et al. (2007) An obligatory role of mind bomb-1 in notch signaling of mammalian development. PLoS ONE 2: e1221.
    • (2007) PLoS ONE , vol.2
    • Koo, B.K.1    Yoon, M.J.2    Yoon, K.J.3    Im, S.K.4    Kim, Y.Y.5
  • 15
    • 37349111560 scopus 로고    scopus 로고
    • RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
    • Li S, Wang L, Berman MA, Zhang Y, Dorf ME, (2006) RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling. Mol Cell 24: 497-509.
    • (2006) Mol Cell , vol.24 , pp. 497-509
    • Li, S.1    Wang, L.2    Berman, M.A.3    Zhang, Y.4    Dorf, M.E.5
  • 16
    • 58149301485 scopus 로고    scopus 로고
    • PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination
    • Li S, Wang L, Dorf ME, (2009) PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination. Mol Cell 33: 30-42.
    • (2009) Mol Cell , vol.33 , pp. 30-42
    • Li, S.1    Wang, L.2    Dorf, M.E.3
  • 17
    • 39149114737 scopus 로고    scopus 로고
    • Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signaling
    • Di Y, Li S, Wang L, Zhang Y, Dorf ME, (2008) Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signaling. Cell Signal 20: 705-713.
    • (2008) Cell Signal , vol.20 , pp. 705-713
    • Di, Y.1    Li, S.2    Wang, L.3    Zhang, Y.4    Dorf, M.E.5
  • 18
    • 34547188530 scopus 로고    scopus 로고
    • Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes
    • Ikeda F, Hecker CM, Rozenknop A, Nordmeier RD, Rogov V, et al. (2007) Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes. EMBO J 26: 3451-3462.
    • (2007) EMBO J , vol.26 , pp. 3451-3462
    • Ikeda, F.1    Hecker, C.M.2    Rozenknop, A.3    Nordmeier, R.D.4    Rogov, V.5
  • 20
    • 77649314475 scopus 로고    scopus 로고
    • Expanding the substantial interactome of NEMO using protein microarrays
    • Fenner BJ, Scannell M, Prehn JH, (2010) Expanding the substantial interactome of NEMO using protein microarrays. PLoS One 5: e8799.
    • (2010) PLoS One , vol.5
    • Fenner, B.J.1    Scannell, M.2    Prehn, J.H.3
  • 21
    • 12144289400 scopus 로고    scopus 로고
    • A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway
    • Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, et al. (2004) A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nat Cell Biol 6: 97-105.
    • (2004) Nat Cell Biol , vol.6 , pp. 97-105
    • Bouwmeester, T.1    Bauch, A.2    Ruffner, H.3    Angrand, P.O.4    Bergamini, G.5
  • 22
    • 34249058119 scopus 로고    scopus 로고
    • The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways
    • Zhao T, Yang L, Sun Q, Arguello M, Ballard DW, et al. (2007) The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol 8: 592-600.
    • (2007) Nat Immunol , vol.8 , pp. 592-600
    • Zhao, T.1    Yang, L.2    Sun, Q.3    Arguello, M.4    Ballard, D.W.5
  • 23
    • 70350004240 scopus 로고    scopus 로고
    • Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3
    • Zeng W, Xu M, Liu S, Sun L, Chen ZJ, (2009) Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol Cell 36: 315-325.
    • (2009) Mol Cell , vol.36 , pp. 315-325
    • Zeng, W.1    Xu, M.2    Liu, S.3    Sun, L.4    Chen, Z.J.5
  • 24
    • 79251566745 scopus 로고    scopus 로고
    • Novel cross-talk within the IKK family controls innate immunity
    • Clark K, Peggie M, Plater L, Sorcek RJ, Young ER, et al. (2011) Novel cross-talk within the IKK family controls innate immunity. Biochem J 434: 93-104.
    • (2011) Biochem J , vol.434 , pp. 93-104
    • Clark, K.1    Peggie, M.2    Plater, L.3    Sorcek, R.J.4    Young, E.R.5
  • 25
    • 79951679142 scopus 로고    scopus 로고
    • Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
    • Barber GN, (2011) Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Curr Opin Immunol 23: 10-20.
    • (2011) Curr Opin Immunol , vol.23 , pp. 10-20
    • Barber, G.N.1
  • 26
    • 77950476766 scopus 로고    scopus 로고
    • Sensing and signaling in antiviral innate immunity
    • O'Neill LA, Bowie AG, (2010) Sensing and signaling in antiviral innate immunity. Curr Biol 20: R328-333.
    • (2010) Curr Biol , vol.20
    • O'Neill, L.A.1    Bowie, A.G.2
  • 27
    • 84857937262 scopus 로고    scopus 로고
    • STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway
    • Tanaka Y, Chen ZJ, (2012) STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway. Sci Signal 5: ra20.
    • (2012) Sci Signal , vol.5
    • Tanaka, Y.1    Chen, Z.J.2
  • 28
    • 63649116570 scopus 로고    scopus 로고
    • Ubiquitylation in innate and adaptive immunity
    • Bhoj VG, Chen ZJ, (2009) Ubiquitylation in innate and adaptive immunity. Nature 458: 430-437.
    • (2009) Nature , vol.458 , pp. 430-437
    • Bhoj, V.G.1    Chen, Z.J.2
  • 29
    • 84862815491 scopus 로고    scopus 로고
    • NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4
    • Cui J, Li Y, Zhu L, Liu D, Songyang Z, et al. (2012) NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. Nat Immunol 13: 387-395.
    • (2012) Nat Immunol , vol.13 , pp. 387-395
    • Cui, J.1    Li, Y.2    Zhu, L.3    Liu, D.4    Songyang, Z.5
  • 30
    • 34247341367 scopus 로고    scopus 로고
    • TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
    • Gack MU, Shin YC, Joo CH, Urano T, Liang C, et al. (2007) TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 446: 916-920.
    • (2007) Nature , vol.446 , pp. 916-920
    • Gack, M.U.1    Shin, Y.C.2    Joo, C.H.3    Urano, T.4    Liang, C.5
  • 31
    • 30544451546 scopus 로고    scopus 로고
    • Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
    • Hacker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, et al. (2006) Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439: 204-207.
    • (2006) Nature , vol.439 , pp. 204-207
    • Hacker, H.1    Redecke, V.2    Blagoev, B.3    Kratchmarova, I.4    Hsu, L.C.5
  • 32
    • 30544447047 scopus 로고    scopus 로고
    • Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
    • Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, et al. (2006) Critical role of TRAF3 in the Toll-like receptor-dependent and-independent antiviral response. Nature 439: 208-211.
    • (2006) Nature , vol.439 , pp. 208-211
    • Oganesyan, G.1    Saha, S.K.2    Guo, B.3    He, J.Q.4    Shahangian, A.5
  • 33
    • 36448943427 scopus 로고    scopus 로고
    • DUBA: a deubiquitinase that regulates type I interferon production
    • Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, et al. (2007) DUBA: a deubiquitinase that regulates type I interferon production. Science 318: 1628-1632.
    • (2007) Science , vol.318 , pp. 1628-1632
    • Kayagaki, N.1    Phung, Q.2    Chan, S.3    Chaudhari, R.4    Quan, C.5
  • 34
    • 49649123561 scopus 로고    scopus 로고
    • Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD
    • Zhang M, Wu X, Lee AJ, Jin W, Chang M, et al. (2008) Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD. J Biol Chem 283: 18621-18626.
    • (2008) J Biol Chem , vol.283 , pp. 18621-18626
    • Zhang, M.1    Wu, X.2    Lee, A.J.3    Jin, W.4    Chang, M.5
  • 35
    • 69049086481 scopus 로고    scopus 로고
    • TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
    • Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, et al. (2009) TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 10: 965-972.
    • (2009) Nat Immunol , vol.10 , pp. 965-972
    • Kawagoe, T.1    Takeuchi, O.2    Takabatake, Y.3    Kato, H.4    Isaka, Y.5
  • 36
    • 77952503750 scopus 로고    scopus 로고
    • Peroxisomes are signaling platforms for antiviral innate immunity
    • Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, et al. (2010) Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141: 668-681.
    • (2010) Cell , vol.141 , pp. 668-681
    • Dixit, E.1    Boulant, S.2    Zhang, Y.3    Lee, A.S.4    Odendall, C.5
  • 37
    • 78650177936 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1
    • Lei CQ, Zhong B, Zhang Y, Zhang J, Wang S, et al. (2010) Glycogen synthase kinase 3beta regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1. Immunity 33: 878-889.
    • (2010) Immunity , vol.33 , pp. 878-889
    • Lei, C.Q.1    Zhong, B.2    Zhang, Y.3    Zhang, J.4    Wang, S.5
  • 38
    • 80052675864 scopus 로고    scopus 로고
    • IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1
    • Liu XY, Chen W, Wei B, Shan YF, Wang C, (2011) IFN-induced TPR protein IFIT3 potentiates antiviral signaling by bridging MAVS and TBK1. J Immunol 187: 2559-2568.
    • (2011) J Immunol , vol.187 , pp. 2559-2568
    • Liu, X.Y.1    Chen, W.2    Wei, B.3    Shan, Y.F.4    Wang, C.5
  • 39
    • 33644860460 scopus 로고    scopus 로고
    • Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells
    • Yang K, Shi H, Qi R, Sun S, Tang Y, et al. (2006) Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells. Mol Biol Cell 17: 1461-1471.
    • (2006) Mol Biol Cell , vol.17 , pp. 1461-1471
    • Yang, K.1    Shi, H.2    Qi, R.3    Sun, S.4    Tang, Y.5
  • 40
    • 79961133270 scopus 로고    scopus 로고
    • MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
    • Hou F, Sun L, Zheng H, Skaug B, Jiang QX, et al. (2011) MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 146: 448-461.
    • (2011) Cell , vol.146 , pp. 448-461
    • Hou, F.1    Sun, L.2    Zheng, H.3    Skaug, B.4    Jiang, Q.X.5


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