-
1
-
-
67650744586
-
The role of ubiquitin in NF-kappaB regulatory pathways
-
Skaug B, Jiang X, Chen ZJ (2009) The role of ubiquitin in NF-kappaB regulatory pathways. Annu Rev Biochem 78: 769-796.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 769-796
-
-
Skaug, B.1
Jiang, X.2
Chen, Z.J.3
-
2
-
-
0022481133
-
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
-
Sen R, Baltimore D (1986) Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46: 705-716.
-
(1986)
Cell
, vol.46
, pp. 705-716
-
-
Sen, R.1
Baltimore, D.2
-
3
-
-
65249140695
-
NF-kappaB regulation: The nuclear response
-
Mankan AK, Lawless MW, Gray SG, Kelleher D, McManus R (2009) NF-kappaB regulation: the nuclear response. J Cell Mol Med 13: 631-643.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 631-643
-
-
Mankan, A.K.1
Lawless, M.W.2
Gray, S.G.3
Kelleher, D.4
McManus, R.5
-
4
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M (2009) Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27: 693-733.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
5
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
-
Yamaoka S, Courtois G, Bessia C, Whiteside ST, Weil R, et al. (1998) Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93: 1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
Whiteside, S.T.4
Weil, R.5
-
6
-
-
0034353188
-
Activation of the Ikappa B kinases by RIP via IKKgamma/NEMO-mediated oligomerization
-
Poyet JL, Srinivasula SM, Lin JH, Fernandes-Alnemri T, Yamaoka S, et al. (2000) Activation of the Ikappa B kinases by RIP via IKKgamma/NEMO-mediated oligomerization. J Biol Chem 275: 37966-37977.
-
(2000)
J Biol Chem
, vol.275
, pp. 37966-37977
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Lin, J.H.3
Fernandes-Alnemri, T.4
Yamaoka, S.5
-
7
-
-
0035887525
-
Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1 beta-stimulated nuclear factor kappa B (NF-kappa B) pathway activation: IRAK-1 associates with the NF-kappa B essential modulator (NEMO) upon receptor stimulation
-
Cooke EL, Uings IJ, Xia CL, Woo P, Ray KP (2001) Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1 beta-stimulated nuclear factor kappa B (NF-kappa B) pathway activation: IRAK-1 associates with the NF-kappa B essential modulator (NEMO) upon receptor stimulation. Biochem J 359: 403-410.
-
(2001)
Biochem J
, vol.359
, pp. 403-410
-
-
Cooke, E.L.1
Uings, I.J.2
Xia, C.L.3
Woo, P.4
Ray, K.P.5
-
8
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ (2006) Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 22: 245-257.
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
9
-
-
33744951304
-
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation
-
Li H, Kobayashi M, Blonska M, You Y, Lin X (2006) Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. J Biol Chem 281: 13636-13643.
-
(2006)
J Biol Chem
, vol.281
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
10
-
-
33645703930
-
Sensing of Lys63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD (2006) Sensing of Lys63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation. Nat Cell Biol 8: 398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
11
-
-
59149093017
-
The zinc finger of NEMO is a functional ubiquitin-binding domain
-
Cordier F, Grubisha O, Traincard F, Veron M, Delepierre M, et al. (2009) The zinc finger of NEMO is a functional ubiquitin-binding domain. J Biol Chem 284: 2902-2907.
-
(2009)
J Biol Chem
, vol.284
, pp. 2902-2907
-
-
Cordier, F.1
Grubisha, O.2
Traincard, F.3
Veron, M.4
Delepierre, M.5
-
13
-
-
33644538632
-
Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli
-
Wu ZH, Shi Y, Tibbetts RS, Miyamoto S (2006) Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli. Science 311: 1141-1146.
-
(2006)
Science
, vol.311
, pp. 1141-1146
-
-
Wu, Z.H.1
Shi, Y.2
Tibbetts, R.S.3
Miyamoto, S.4
-
14
-
-
33748188499
-
PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress
-
Mabb AM, Wuerzberger-Davis SM, Miyamoto S (2006) PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress. Nat Cell Biol 8: 986-993.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 986-993
-
-
Mabb, A.M.1
Wuerzberger-Davis, S.M.2
Miyamoto, S.3
-
15
-
-
47949129452
-
Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress
-
Wu ZH, Miyamoto S (2008) Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress. EMBO J 27: 1963-1973.
-
(2008)
EMBO J
, vol.27
, pp. 1963-1973
-
-
Wu, Z.H.1
Miyamoto, S.2
-
16
-
-
33750312876
-
Posttranslational modifications of NEMO and its partners in NF-kappaB signaling
-
Sebban H, Yamaoka S, Courtois G (2006) Posttranslational modifications of NEMO and its partners in NF-kappaB signaling. Trends Cell Biol 16: 569-577.
-
(2006)
Trends Cell Biol
, vol.16
, pp. 569-577
-
-
Sebban, H.1
Yamaoka, S.2
Courtois, G.3
-
17
-
-
12144289400
-
A physical and functional map of the human TNF-alpha/NF-kappaB signal transduction pathway
-
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, et al. (2004) A physical and functional map of the human TNF-alpha/NF-kappaB signal transduction pathway. Nat Cell Biol 6: 97-105.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 97-105
-
-
Bouwmeester, T.1
Bauch, A.2
Ruffner, H.3
Angrand, P.O.4
Bergamini, G.5
-
18
-
-
0037020147
-
Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases
-
Chariot A, Leonardi A, Muller J, Bonif M, Brown K, et al. (2002) Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases. J Biol Chem 277: 37029-37036.
-
(2002)
J Biol Chem
, vol.277
, pp. 37029-37036
-
-
Chariot, A.1
Leonardi, A.2
Muller, J.3
Bonif, M.4
Brown, K.5
-
19
-
-
58149098926
-
Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1
-
Higashimoto T, Chan N, Lee YK, Zandi E (2008) Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1. J Biol Chem 283: 35354-35367.
-
(2008)
J Biol Chem
, vol.283
, pp. 35354-35367
-
-
Higashimoto, T.1
Chan, N.2
Lee, Y.K.3
Zandi, E.4
-
20
-
-
0043210473
-
Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1
-
Kim YS, Lee JY, Son MY, Park W, Bae YS (2003) Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1. J Biol Chem 278: 28462-28469.
-
(2003)
J Biol Chem
, vol.278
, pp. 28462-28469
-
-
Kim, Y.S.1
Lee, J.Y.2
Son, M.Y.3
Park, W.4
Bae, Y.S.5
-
21
-
-
34447118188
-
RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation
-
Tian Y, Zhang Y, Zhong B, Wang YY, Diao FC, et al. (2007) RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation. J Biol Chem 282: 16776-16782.
-
(2007)
J Biol Chem
, vol.282
, pp. 16776-16782
-
-
Tian, Y.1
Zhang, Y.2
Zhong, B.3
Wang, Y.Y.4
Diao, F.C.5
-
22
-
-
35548991803
-
Tag team action at the synapse
-
Carr CM, Munson M (2007) Tag team action at the synapse. EMBO Rep 8: 834-838.
-
(2007)
EMBO Rep
, vol.8
, pp. 834-838
-
-
Carr, C.M.1
Munson, M.2
-
23
-
-
52049098892
-
Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-kappaB signaling pathway
-
Wang HJ, Cao JP, Yu JK, Zhang LC, Jiang ZJ, et al. (2008) Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-kappaB signaling pathway. Eur J Pharmacol 595: 7-12.
-
(2008)
Eur J Pharmacol
, vol.595
, pp. 7-12
-
-
Wang, H.J.1
Cao, J.P.2
Yu, J.K.3
Zhang, L.C.4
Jiang, Z.J.5
-
24
-
-
0032575565
-
Association of Cdk2/cyclin E and NF-kappa B complexes at G1/S phase
-
Chen E, Li CC (1998) Association of Cdk2/cyclin E and NF-kappa B complexes at G1/S phase. Biochem Biophys Res Commun 249: 728-734.
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 728-734
-
-
Chen, E.1
Li, C.C.2
-
25
-
-
34548846689
-
SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/ NF-kappaB
-
Gu Q, Bowden GT, Normolle D, Sun Y (2007) SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/ NF-kappaB. J Cell Biol 178: 1009-1023.
-
(2007)
J Cell Biol
, vol.178
, pp. 1009-1023
-
-
Gu, Q.1
Bowden, G.T.2
Normolle, D.3
Sun, Y.4
-
27
-
-
9144243918
-
The synaptotagmins: Calcium sensors for vesicular trafficking
-
Yoshihara M, Montana ES (2004) The synaptotagmins: calcium sensors for vesicular trafficking. Neuroscientist 10: 566-574.
-
(2004)
Neuroscientist
, vol.10
, pp. 566-574
-
-
Yoshihara, M.1
Montana, E.S.2
-
28
-
-
0141960930
-
Synaptotagmin I, a Ca2+ sensor for neurotransmitter release
-
Koh TW, Bellen HJ (2003) Synaptotagmin I, a Ca2+ sensor for neurotransmitter release. Trends Neurosci 26: 413-422.
-
(2003)
Trends Neurosci
, vol.26
, pp. 413-422
-
-
Koh, T.W.1
Bellen, H.J.2
-
31
-
-
33644778718
-
Rapid identification of 14-3-3-binding proteins by protein microarray analysis
-
Satoh J, Nanri Y, Yamamura T (2006) Rapid identification of 14-3-3-binding proteins by protein microarray analysis. J Neurosci Methods 152: 278-288.
-
(2006)
J Neurosci Methods
, vol.152
, pp. 278-288
-
-
Satoh, J.1
Nanri, Y.2
Yamamura, T.3
-
32
-
-
54549100243
-
Pituitary tumor transforming gene 1 regulates Aurora kinase A activity
-
Tong Y, Ben-Shlomo A, Zhou C, Wawrowsky K, Melmed S (2008) Pituitary tumor transforming gene 1 regulates Aurora kinase A activity. Oncogene 27: 6385-6395.
-
(2008)
Oncogene
, vol.27
, pp. 6385-6395
-
-
Tong, Y.1
Ben-Shlomo, A.2
Zhou, C.3
Wawrowsky, K.4
Melmed, S.5
-
33
-
-
58849108962
-
Protein microarray analysis identifies human cellular prion protein interactors
-
Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, et al. (2009) Protein microarray analysis identifies human cellular prion protein interactors. Neuropathol Appl Neurobiol 35: 16-35.
-
(2009)
Neuropathol Appl Neurobiol
, vol.35
, pp. 16-35
-
-
Satoh, J.1
Obayashi, S.2
Misawa, T.3
Sumiyoshi, K.4
Oosumi, K.5
-
35
-
-
33745813182
-
Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K)
-
Kojetin DJ, Venters RA, Kordys DR, Thompson RJ, Kumar R, et al. (2006) Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K). Nat Struct Mol Biol 13: 641-647.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 641-647
-
-
Kojetin, D.J.1
Venters, R.A.2
Kordys, D.R.3
Thompson, R.J.4
Kumar, R.5
-
36
-
-
33846128759
-
Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli
-
Berchtold CM, Wu ZH, Huang TT, Miyamoto S (2007) Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. Mol Cell Biol 27: 497-509.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 497-509
-
-
Berchtold, C.M.1
Wu, Z.H.2
Huang, T.T.3
Miyamoto, S.4
-
37
-
-
17144407633
-
Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor
-
Madziva MT, Bai J, Bhalla A, Chapman ER, Edwardson JM (2005) Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor. Br J Pharmacol 144: 761-771.
-
(2005)
Br J Pharmacol
, vol.144
, pp. 761-771
-
-
Madziva, M.T.1
Bai, J.2
Bhalla, A.3
Chapman, E.R.4
Edwardson, J.M.5
-
38
-
-
33845583328
-
SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection
-
Tan M, Gallegos JR, Gu Q, Huang Y, Li J, et al. (2006) SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection. Neoplasia 8: 1042-1054.
-
(2006)
Neoplasia
, vol.8
, pp. 1042-1054
-
-
Tan, M.1
Gallegos, J.R.2
Gu, Q.3
Huang, Y.4
Li, J.5
-
39
-
-
0034987067
-
Attenuation of ischemiainduced mouse brain injury by SAG, a redox-inducible antioxidant protein
-
Yang GY, Pang L, Ge HL, Tan M, Ye W, et al. (2001) Attenuation of ischemiainduced mouse brain injury by SAG, a redox-inducible antioxidant protein. J Cereb Blood Flow Metab 21: 722-733.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 722-733
-
-
Yang, G.Y.1
Pang, L.2
Ge, H.L.3
Tan, M.4
Ye, W.5
-
40
-
-
39849098721
-
SAG/ROC2/ RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation
-
Tan M, Gu Q, He H, Pamarthy D, Semenza GL, et al. (2008) SAG/ROC2/ RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation. Oncogene 27: 1404-1411.
-
(2008)
Oncogene
, vol.27
, pp. 1404-1411
-
-
Tan, M.1
Gu, Q.2
He, H.3
Pamarthy, D.4
Semenza, G.L.5
-
41
-
-
0344305376
-
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
-
Huang TT, Wuerzberger-Davis SM, Wu ZH, Miyamoto S (2003) Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 115: 565-576.
-
(2003)
Cell
, vol.115
, pp. 565-576
-
-
Huang, T.T.1
Wuerzberger-Davis, S.M.2
Wu, Z.H.3
Miyamoto, S.4
-
42
-
-
33846783142
-
NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage
-
Wuerzberger-Davis SM, Nakamura Y, Seufzer BJ, Miyamoto S (2007) NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage. Oncogene 26: 641-651.
-
(2007)
Oncogene
, vol.26
, pp. 641-651
-
-
Wuerzberger-Davis, S.M.1
Nakamura, Y.2
Seufzer, B.J.3
Miyamoto, S.4
-
43
-
-
1842538832
-
Modifying NEMO
-
Hay RT (2004) Modifying NEMO. Nat Cell Biol 6: 89-91.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 89-91
-
-
Hay, R.T.1
-
44
-
-
0036724599
-
Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex
-
Zhang H, Saitoh H, Matunis MJ (2002) Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex. Mol Cell Biol 22: 6498-6508.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6498-6508
-
-
Zhang, H.1
Saitoh, H.2
Matunis, M.J.3
-
45
-
-
34249880519
-
Modification in reverse: The SUMO proteases
-
Mukhopadhyay D, Dasso M (2007) Modification in reverse: the SUMO proteases. Trends Biochem Sci 32: 286-295.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 286-295
-
-
Mukhopadhyay, D.1
Dasso, M.2
-
46
-
-
65149091876
-
-
Antioxid Redox Signal
-
Au SW, Lam KH, Lam WL, Lam LS, Chan HY, et al. (2009) SUMO proteases: Redox regulation and biological consequences. Antioxid Redox Signal.
-
(2009)
SUMO proteases: Redox regulation and biological consequences
-
-
Au, S.W.1
Lam, K.H.2
Lam, W.L.3
Lam, L.S.4
Chan, H.Y.5
-
47
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IkappaB kinases essential for NF-kappaB activation
-
Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, et al. (1997) IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science 278: 860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
-
48
-
-
0027742184
-
Distinct roles for cyclin-dependent kinases in cell cycle control
-
van den Heuvel S, Harlow E (1993) Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262: 2050-2054.
-
(1993)
Science
, vol.262
, pp. 2050-2054
-
-
van den Heuvel, S.1
Harlow, E.2
-
49
-
-
2942735131
-
SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1
-
Cheng J, Wang D, Wang Z, Yeh ET (2004) SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1. Mol Cell Biol 24: 6021-6028.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6021-6028
-
-
Cheng, J.1
Wang, D.2
Wang, Z.3
Yeh, E.T.4
-
50
-
-
0035336994
-
A cell-based assay system for monitoring NF-kappaB activity in human HaCat transfectant cells
-
Moon KY, Hahn BS, Lee J, Kim YS (2001) A cell-based assay system for monitoring NF-kappaB activity in human HaCat transfectant cells. Anal Biochem 292: 17-21.
-
(2001)
Anal Biochem
, vol.292
, pp. 17-21
-
-
Moon, K.Y.1
Hahn, B.S.2
Lee, J.3
Kim, Y.S.4
|