-
1
-
-
1942531962
-
An update on the cytokine network in rheumatoid arthritis
-
Miossec, P. An update on the cytokine network in rheumatoid arthritis. Curr. Opin. Rheumatol. 2004, 16, 218–222. [CrossRef] [PubMed]
-
(2004)
Curr. Opin. Rheumatol.
, vol.16
, pp. 218-222
-
-
Miossec, P.1
-
2
-
-
34247155347
-
Emerging cytokine targets in rheumatoid arthritis
-
Asquith, D.L.; McInnes, I.B. Emerging cytokine targets in rheumatoid arthritis. Curr. Opin. Rheumatol. 2007, 19, 246–251. [CrossRef] [PubMed]
-
(2007)
Curr. Opin. Rheumatol
, vol.19
, pp. 246-251
-
-
Asquith, D.L.1
McInnes, I.B.2
-
3
-
-
84982683034
-
Anti cytokine therapy in chronic inflammatory arthritis
-
Thompson, C.; Davies, R.; Choy, E. Anti cytokine therapy in chronic inflammatory arthritis. Cytokine 2016, 86, 92–99. [CrossRef] [PubMed]
-
(2016)
Cytokine
, vol.86
, pp. 92-99
-
-
Thompson, C.1
Davies, R.2
Choy, E.3
-
4
-
-
84960934172
-
Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis
-
Mateen, S.; Zafar, A.; Moin, S.; Khan, A.Q.; Zubair, S. Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis. Clin. Chim. Acta 2016, 455, 161–171. [CrossRef] [PubMed]
-
(2016)
Clin. Chim. Acta
, vol.455
, pp. 161-171
-
-
Mateen, S.1
Zafar, A.2
Moin, S.3
Khan, A.Q.4
Zubair, S.5
-
5
-
-
84870916952
-
Evolution of treatment from rheumatoid arthritis
-
Upchurch, K.S.; Kay, J. Evolution of treatment from rheumatoid arthritis. Rheumatology 2012, 6, vi28–vi36.
-
(2012)
Rheumatology
, vol.6
, pp. vi28-vi36
-
-
Upchurch, K.S.1
Kay, J.2
-
6
-
-
84926303946
-
Biological basis of osteoarthritis: State of the evidence
-
Malemud, C.J. The biological basis of osteoarthritis: State of the evidence. Curr. Opin. Rheumatol. 2015, 27, 289–294. [CrossRef] [PubMed]
-
(2015)
Curr. Opin. Rheumatol
, vol.27
, pp. 289-294
-
-
Malemud, C.J.T.1
-
7
-
-
77950864738
-
Osteoarthritis: Can anti-cytokine therapy play a role in treatment?
-
Calich, A.L.; Domiciano, D.S.; Fuller, R. Osteoarthritis: Can anti-cytokine therapy play a role in treatment? Clin. Rheumatol. 2010, 29, 451–455. [CrossRef] [PubMed]
-
(2010)
Clin. Rheumatol
, vol.29
, pp. 451-455
-
-
Calich, A.L.1
Domiciano, D.S.2
Fuller, R.3
-
8
-
-
0038653361
-
Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies
-
Malemud, C.J.; Islam, N.; Haqqi, T.M. Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies. Cells Tissues Organs 2003, 174, 34–38. [CrossRef] [PubMed]
-
(2003)
Cells Tissues Organs
, vol.174
, pp. 34-38
-
-
Malemud, C.J.1
Islam, N.2
Haqqi, T.M.3
-
9
-
-
0031919849
-
JAKS and STATs: Biological implications
-
Leonard, W.J.; O’Shea, J.J. JAKS and STATs: Biological implications. Annu. Rev. Immunol. 1998, 16, 293–322. [CrossRef] [PubMed]
-
(1998)
Annu. Rev. Immunol
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O’Shea, J.J.2
-
10
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker, T.; Kovarik, P. Serine phosphorylation of STATs. Oncogene 2000, 19, 2628–2637. [CrossRef] [PubMed]
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
11
-
-
0034722896
-
STAT proteins: Novel molecular targets for cancer drug discovery
-
Turkson, J.; Jove, R. STAT proteins: Novel molecular targets for cancer drug discovery. Oncogene 2000, 19, 6613–6626. [CrossRef] [PubMed]
-
(2000)
Oncogene
, vol.19
, pp. 6613-6626
-
-
Turkson, J.1
Jove, R.2
-
12
-
-
77149137827
-
Targeting JAK/STAT signaling pathway in inflammatory diseases
-
Malemud, C.J.; Pearlman, E. Targeting JAK/STAT signaling pathway in inflammatory diseases. Curr. Signal Transduct. Ther. 2009, 4, 201–221. [CrossRef]
-
(2009)
Curr. Signal Transduct. Ther
, vol.4
, pp. 201-221
-
-
Malemud, C.J.1
Pearlman, E.2
-
13
-
-
18244392419
-
STAT4: A critical regulator of inflammation in vivo
-
Kaplan, M.H. STAT4: A critical regulator of inflammation in vivo. Immunol. Res. 2005, 31, 231–242. [CrossRef]
-
(2005)
Immunol. Res
, vol.31
, pp. 231-242
-
-
Kaplan, M.H.1
-
14
-
-
33751555600
-
General nature of STAT3-activated anti-inflammatory response
-
El Kasmi, K.C.; Holst, J.; Coffre, M.; Mielke, L.; DePauw, A.; Lhocine, N.; Smith, A.M.; Rutschman, R.; Kaushal, D.; Shen, Y.; et al. General nature of STAT3-activated anti-inflammatory response. J. Immunol. 2006, 177, 7880–7888. [CrossRef] [PubMed]
-
(2006)
J. Immunol
, vol.177
, pp. 7880-7888
-
-
El Kasmi, K.C.1
Holst, J.2
Coffre, M.3
Mielke, L.4
Depauw, A.5
Lhocine, N.6
Smith, A.M.7
Rutschman, R.8
Kaushal, D.9
Shen, Y.10
-
16
-
-
74849090711
-
Emerging from the shadows: Follicular helper T cells in autoimmunity
-
DiPlacido, L.D.; Craft, J. Emerging from the shadows: Follicular helper T cells in autoimmunity. Arthritis Rheumatol. 2010, 62, 6–8. [CrossRef] [PubMed]
-
(2010)
Arthritis Rheumatol
, vol.62
, pp. 6-8
-
-
Diplacido, L.D.1
Craft, J.2
-
17
-
-
84960894417
-
Janus kinase inhibitors for rheumatoid arthritis
-
Yamaoka, K. Janus kinase inhibitors for rheumatoid arthritis. Curr. Opin. Chem. Biol. 2016, 32, 29–33. [CrossRef] [PubMed]
-
(2016)
Curr. Opin. Chem. Biol
, vol.32
, pp. 29-33
-
-
Yamaoka, K.1
-
18
-
-
79959975619
-
Dysfunctional immune-mediated inflammation in rheumatoid arthritis dictates that development of anti-rheumatic disease drugs target multiple intracellular signaling pathways
-
Malemud, C.J. Dysfunctional immune-mediated inflammation in rheumatoid arthritis dictates that development of anti-rheumatic disease drugs target multiple intracellular signaling pathways. Antiinflamm. Antiallergy Agents Med. Chem. 2011, 10, 78–84. [CrossRef] [PubMed]
-
(2011)
Antiinflamm. Antiallergy Agents Med. Chem
, vol.10
, pp. 78-84
-
-
Malemud, C.J.1
-
19
-
-
84954197348
-
Cytokines in rheumatoid arthritis—Shaping the immunological landscape
-
McInnes, I.B.; Buckley, C.D.; Isaacs, J.D. Cytokines in rheumatoid arthritis—Shaping the immunological landscape. Nat. Rev. Rheumatol. 2016, 12, 63–68. [CrossRef] [PubMed]
-
(2016)
Nat. Rev. Rheumatol.
, vol.12
, pp. 63-68
-
-
McInnes, I.B.1
Buckley, C.D.2
Isaacs, J.D.3
-
20
-
-
84859992161
-
The JAK-STAT pathway at 20
-
Stark, G.R.; Darnell, J.E., Jr. The JAK-STAT pathway at 20. Immunity 2012, 36, 503–514. [CrossRef] [PubMed]
-
(2012)
Immunity
, vol.36
, pp. 503-514
-
-
Stark, G.R.1
Darnell, J.E.2
-
21
-
-
34248331345
-
Inhibitors of stress-activated/mitogen-activated protein kinase pathways
-
Malemud, C.J. Inhibitors of stress-activated/mitogen-activated protein kinase pathways. Curr. Opin. Pharmacol. 2007, 7, 339–343. [CrossRef] [PubMed]
-
(2007)
Curr. Opin. Pharmacol
, vol.7
, pp. 339-343
-
-
Malemud, C.J.1
-
22
-
-
84860242496
-
Targeted drug development for arthritis
-
Malemud, C.J. Targeted drug development for arthritis. Future Med. Chem. 2012, 4, 701–703. [CrossRef] [PubMed]
-
(2012)
Future Med. Chem
, vol.4
, pp. 701-703
-
-
Malemud, C.J.1
-
23
-
-
84901248425
-
Kinase inhibitors: The next generation of therapies in the treatment of rheumatoid arthritis
-
MacFarlane, L.A.; Todd, D.J. Kinase inhibitors: The next generation of therapies in the treatment of rheumatoid arthritis. Int. J. Rheum. Dis. 2014, 17, 359–368. [CrossRef] [PubMed]
-
(2014)
Int. J. Rheum. Dis
, vol.17
, pp. 359-368
-
-
Macfarlane, L.A.1
Todd, D.J.2
-
24
-
-
84890806562
-
Therapeutic targeting of the Jak/STAT pathway
-
Aittomäki, S.; Pesu, M. Therapeutic targeting of the Jak/STAT pathway. Basic Clin. Pharmacol. Toxicol. 2014, 114, 18–23. [CrossRef] [PubMed]
-
(2014)
Basic Clin. Pharmacol. Toxicol
, vol.114
, pp. 18-23
-
-
Aittomäki, S.1
Pesu, M.2
-
25
-
-
78650924647
-
Treating inflammation with the Janus kinase inhibitor CP-690,550
-
Vijayakrishnan, L.; Venkataramanan, R.; Gulati, P. Treating inflammation with the Janus kinase inhibitor CP-690,550. Trends Pharmacol. Sci. 2011, 32, 25–34. [CrossRef] [PubMed]
-
(2011)
Trends Pharmacol. Sci
, vol.32
, pp. 25-34
-
-
Vijayakrishnan, L.1
Venkataramanan, R.2
Gulati, P.3
-
26
-
-
77953208379
-
Ruxolitinib, a selective JAK1 and JAK2 inhibitor for the treatment of myeloproliferative neoplasms and psoriasis
-
Mesa, A. Ruxolitinib, a selective JAK1 and JAK2 inhibitor for the treatment of myeloproliferative neoplasms and psoriasis. IDrugs 2010, 13, 394–403. [PubMed]
-
(2010)
Idrugs
, vol.13
, pp. 394-403
-
-
Mesa, A.1
-
27
-
-
84878216601
-
Investigational Janus kinase inhibitors
-
Tam, C.S.; Verstovsek, S. Investigational Janus kinase inhibitors. Expert Opin. Investig. Drugs 2013, 22, 687–699. [CrossRef] [PubMed]
-
(2013)
Expert Opin. Investig. Drugs
, vol.22
, pp. 687-699
-
-
Tam, C.S.1
Verstovsek, S.2
-
28
-
-
85014102709
-
The small molecular weight inhibitor of protein kinase revolution for the treatment of rheumatoid arthritis
-
Vallisuta, O., Olimat, S., Eds.; InTech Publishing: Rijeka, Croatia
-
Malemud, C.J. The small molecular weight inhibitor of protein kinase revolution for the treatment of rheumatoid arthritis. In Drug Discovery and Development—From Molecules to Medicine; Vallisuta, O., Olimat, S., Eds.; InTech Publishing: Rijeka, Croatia, 2015; pp. 163–179.
-
(2015)
Drug Discovery and Development—From Molecules to Medicine
, pp. 163-179
-
-
Malemud, C.J.1
-
29
-
-
84906100280
-
Protein kinase small molecule inhibitors for rheumatoid arthritis: Medicinal chemistry/Clinical perspectives
-
Malemud, C.J.; Blumenthal, D.E. Protein kinase small molecule inhibitors for rheumatoid arthritis: Medicinal chemistry/Clinical perspectives. World J. Orthop. 2014, 5, 496–503. [CrossRef] [PubMed]
-
(2014)
World J. Orthop.
, vol.5
, pp. 496-503
-
-
Malemud, C.J.1
Blumenthal, D.E.2
-
30
-
-
85014120743
-
Suppressor of cytokine signaling and rheumatoid arthritis
-
Malemud, C.J. Suppressor of cytokine signaling and rheumatoid arthritis. Integr. Mol. Med. 2016, 3, 17–20.
-
(2016)
Integr. Mol. Med.
, vol.3
, pp. 17-20
-
-
Malemud, C.J.1
-
31
-
-
32644459132
-
Regulation of cytokine signaling pathways by PIAS proteins
-
Shuai, K. Regulation of cytokine signaling pathways by PIAS proteins. Cell Res. 2006, 16, 196–202. [CrossRef] [PubMed]
-
(2006)
Cell Res
, vol.16
, pp. 196-202
-
-
Shuai, K.1
-
32
-
-
0034841006
-
Negative regulation of cytokine signaling
-
Greenhalgh, C.J.; Hilton, D.J. Negative regulation of cytokine signaling. J. Leukoc. Biol. 2001, 70, 348–356. [PubMed]
-
(2001)
J. Leukoc. Biol
, vol.70
, pp. 348-356
-
-
Greenhalgh, C.J.1
Hilton, D.J.2
-
33
-
-
20144367654
-
Negative regulation of cytokine signaling and immune responses by SOCS proteins
-
Yoshimura, A.; Nishinakamura, H.; Matsumura, Y.; Hanada, T. Negative regulation of cytokine signaling and immune responses by SOCS proteins. Arthritis Res. Ther. 2005, 7, 100–110. [CrossRef] [PubMed]
-
(2005)
Arthritis Res. Ther
, vol.7
, pp. 100-110
-
-
Yoshimura, A.1
Nishinakamura, H.2
Matsumura, Y.3
Hanada, T.4
-
34
-
-
84945919115
-
SOCS3 and its role in associated diseases
-
Yin, Y.; Liu, W.; Dai, Y. SOCS3 and its role in associated diseases. Hum. Immunol. 2015, 76, 775–780. [CrossRef] [PubMed]
-
(2015)
Hum. Immunol
, vol.76
, pp. 775-780
-
-
Yin, Y.1
Liu, W.2
Dai, Y.3
-
35
-
-
84878263233
-
Targeting the JAK-STAT pathway in lymphoma: A focus on pacritinib
-
Derenzini, E.; Younes, A. Targeting the JAK-STAT pathway in lymphoma: A focus on pacritinib. Expert Opin. Investig. Drugs 2013, 22, 775–785. [CrossRef] [PubMed]
-
(2013)
Expert Opin. Investig. Drugs
, vol.22
, pp. 775-785
-
-
Derenzini, E.1
Younes, A.2
-
36
-
-
84964220748
-
STAT5 in cancer and immunity
-
Rani, A.; Murphy, J.J. STAT5 in cancer and immunity. J. Interf. Cytokine Res. 2016, 36, 226–237. [CrossRef] [PubMed]
-
(2016)
J. Interf. Cytokine Res
, vol.36
, pp. 226-237
-
-
Rani, A.1
Murphy, J.J.2
-
37
-
-
84889058668
-
STAT inhibitors for cancer therapy
-
Furgan, M.; Akinleye, A.; Mukhi, N.; Mittal, V.; Chen, Y.; Liu, D. STAT inhibitors for cancer therapy. J. Hematol. Oncol. 2013, 6, 90. [CrossRef] [PubMed]
-
(2013)
J. Hematol. Oncol
, vol.6
, pp. 90
-
-
Furgan, M.1
Akinleye, A.2
Mukhi, N.3
Mittal, V.4
Chen, Y.5
Liu, D.6
-
38
-
-
77950634929
-
Macrophage signaling in HIV-1 infection
-
Herbein, G.; Gras, G.; Khan, K.A.; Abbas, W. Macrophage signaling in HIV-1 infection. Retrovirology 2010, 7, 34. [CrossRef] [PubMed]
-
(2010)
Retrovirology
, vol.7
, pp. 34
-
-
Herbein, G.1
Gras, G.2
Khan, K.A.3
Abbas, W.4
-
39
-
-
84876183232
-
SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition
-
Kershaw, N.J.; Murphy, J.M.; Liau, N.P.; Varghese, L.N.; Laktyushin, A.; Whitlock, E.L.; Lucet, I.S.; Nicola, N.A.; Babon, J.J. SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition. Nat. Struct. Mol. Biol. 2013, 20, 469–476. [CrossRef] [PubMed]
-
(2013)
Nat. Struct. Mol. Biol
, vol.20
, pp. 469-476
-
-
Kershaw, N.J.1
Murphy, J.M.2
Liau, N.P.3
Varghese, L.N.4
Laktyushin, A.5
Whitlock, E.L.6
Lucet, I.S.7
Nicola, N.A.8
Babon, J.J.9
-
40
-
-
0037317179
-
A three-dimensional model of Suppressor of Cytokine Signaling-1 (SOCS-1)
-
Giordanetto, F.; Kroemer, R.T. A three-dimensional model of Suppressor of Cytokine Signaling-1 (SOCS-1). Protein Eng. 2003, 16, 115–124. [CrossRef] [PubMed]
-
(2003)
Protein Eng
, vol.16
, pp. 115-124
-
-
Giordanetto, F.1
Kroemer, R.T.2
-
41
-
-
0037162397
-
SH2 domains from suppressor of cytokine signaling-3 and protein phosphatase SHP-2 have similar binding specificities
-
De Souza, D.; Fabri, L.J.; Nash, A.; Hilton, D.J.; Nicola, N.A.; Baca, M. SH2 domains from suppressor of cytokine signaling-3 and protein phosphatase SHP-2 have similar binding specificities. Biochemistry 2002, 41, 9229–9236. [CrossRef] [PubMed]
-
(2002)
Biochemistry
, vol.41
, pp. 9229-9236
-
-
De Souza, D.1
Fabri, L.J.2
Nash, A.3
Hilton, D.J.4
Nicola, N.A.5
Baca, M.6
-
42
-
-
20844442966
-
Immunological mechanisms in the pathogenesis of rheumatoid arthritis
-
Firestein, G.S. Immunological mechanisms in the pathogenesis of rheumatoid arthritis. J. Clin. Rheumatol. 2005, 11 (Suppl. 3), S39–S44. [CrossRef]
-
(2005)
J. Clin. Rheumatol.
, vol.11
, pp. S39-S44
-
-
Firestein, G.S.1
-
43
-
-
83455169460
-
A cytokine-centric view of the pathogenesis and treatment of rheumatoid arthritis
-
Astry, B.; Harberts, E.; Moudgil, K.D. A cytokine-centric view of the pathogenesis and treatment of rheumatoid arthritis. J. Interf. Cytokine Res. 2011, 31, 927–940. [CrossRef] [PubMed]
-
(2011)
J. Interf. Cytokine Res
, vol.31
, pp. 927-940
-
-
Astry, B.1
Harberts, E.2
Moudgil, K.D.3
-
44
-
-
29844438612
-
Fas (CD95)-related apoptosis and rheumatoid arthritis
-
Peng, S.L. Fas (CD95)-related apoptosis and rheumatoid arthritis. Rheumatology 2006, 45, 26–30. [CrossRef] [PubMed]
-
(2006)
Rheumatology
, vol.45
, pp. 26-30
-
-
Peng, S.L.1
-
45
-
-
84876019491
-
Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes
-
Choe, J.Y.; Park, K.Y.; Park, S.H.; Lee, S.I.; Kim, S.K. Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes. Arthritis Res. Ther. 2013, 15, R26. [CrossRef] [PubMed]
-
(2013)
Arthritis Res. Ther
, vol.15
, pp. R26
-
-
Choe, J.Y.1
Park, K.Y.2
Park, S.H.3
Lee, S.I.4
Kim, S.K.5
-
46
-
-
84987600978
-
The activity of JAK/STAT and NF-κB in patients with rheumatoid arthritis
-
Świerkot, J.; Nowak, B.; Czarny, A.; Zaczyńska, E.; Sokolik, R.; Madej, M.; Korman, L.; Sebastian, A.; Wojtala, P.; Lubiński, L.; et al. The activity of JAK/STAT and NF-κB in patients with rheumatoid arthritis. Adv. Clin. Exp. Med. 2016, 25, 709–717. [CrossRef] [PubMed]
-
(2016)
Adv. Clin. Exp. Med
, vol.25
, pp. 709-717
-
-
Świerkot, J.1
Nowak, B.2
Czarny, A.3
Zaczyńska, E.4
Sokolik, R.5
Madej, M.6
Korman, L.7
Sebastian, A.8
Wojtala, P.9
Lubiński, L.10
-
47
-
-
0035667907
-
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis
-
Shouda, T.; Yoshida, T.; Hanada, T.; Wakioka, T.; Oishi, M.; Miyoshi, K.; Komiya, S.; Kosai, K.; Hanakawa, Y.; Hashimoto, K.; et al. Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. J. Clin. Investig. 2001, 108, 1781–1788. [CrossRef] [PubMed]
-
(2001)
J. Clin. Investig.
, vol.108
, pp. 1781-1788
-
-
Shouda, T.1
Yoshida, T.2
Hanada, T.3
Wakioka, T.4
Oishi, M.5
Miyoshi, K.6
Komiya, S.7
Kosai, K.8
Hanakawa, Y.9
Hashimoto, K.10
-
48
-
-
84965042700
-
SOCS3 revisited: A broad regulator of disease, now ready for therapeutic use?
-
Mahony, R.; Ahmed, S.; Diskin, C.; Stevenson, N.J. SOCS3 revisited: A broad regulator of disease, now ready for therapeutic use? Cell. Mol. Life Sci. 2016, 73, 3323–3336. [CrossRef] [PubMed]
-
(2016)
Cell. Mol. Life Sci
, vol.73
, pp. 3323-3336
-
-
Mahony, R.1
Ahmed, S.2
Diskin, C.3
Stevenson, N.J.4
-
49
-
-
47249124862
-
Is there a final common pathway for arthritis?
-
Malemud, C.J.; Schulte, M.E. Is there a final common pathway for arthritis? Future Rheumatol. 2008, 3, 253–268. [CrossRef]
-
(2008)
Future Rheumatol
, vol.3
, pp. 253-268
-
-
Malemud, C.J.1
Schulte, M.E.2
-
50
-
-
79955066683
-
Matrix metalloproteinase-13 expression in IL-1β-treated chondrocytes by activation of the p38 MAPK/c-Fos/AP-1 and JAK/STAT pathways
-
Lim, H.; Kim, H.P. Matrix metalloproteinase-13 expression in IL-1β-treated chondrocytes by activation of the p38 MAPK/c-Fos/AP-1 and JAK/STAT pathways. Arch. Pharm. Res. 2011, 34, 109–117. [CrossRef] [PubMed]
-
(2011)
Arch. Pharm. Res
, vol.34
, pp. 109-117
-
-
Lim, H.1
Kim, H.P.2
-
51
-
-
0035168098
-
Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes
-
Islam, S.; Kermode, T.; Sultana, D.; Moskowitz, R.W.; Mukhtar, H.; Malemud, C.J.; Goldberg, V.M.; Haqqi, T.M. Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes. Osteoarthr. Cartil. 2001, 9, 684–693. [CrossRef] [PubMed]
-
(2001)
Osteoarthr. Cartil
, vol.9
, pp. 684-693
-
-
Islam, S.1
Kermode, T.2
Sultana, D.3
Moskowitz, R.W.4
Mukhtar, H.5
Malemud, C.J.6
Goldberg, V.M.7
Haqqi, T.M.8
-
52
-
-
79953163645
-
Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis
-
De Andrés, M.C.; Imagawa, K.; Hashimoto, K.; Gonzalez, A.; Goldring, M.B.; Goldring, M.B.; Roach, H.I.; Oreffo, R.O. Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis. Biochem. Biophys. Res. Commun. 2011, 407, 54–59. [CrossRef] [PubMed]
-
(2011)
Biochem. Biophys. Res. Commun
, vol.407
, pp. 54-59
-
-
De Andrés, M.C.1
Imagawa, K.2
Hashimoto, K.3
Gonzalez, A.4
Goldring, M.B.5
Goldring, M.B.6
Roach, H.I.7
Oreffo, R.O.8
-
53
-
-
84954124193
-
Protein inhibitor of activated STAT3 regulates migration, invasion, and activation of fibroblast-like synoviocytes in rheumatoid arthritis
-
Lao, M.; Shi, M.; Zou, Y.; Huang, M.; Ye, Y.; Qiu, Q.; Xiao, Y.; Zeng, S.; Liang, L.; Yang, X.; et al. Protein inhibitor of activated STAT3 regulates migration, invasion, and activation of fibroblast-like synoviocytes in rheumatoid arthritis. J. Immunol. 2016, 196, 596–606. [CrossRef] [PubMed]
-
(2016)
J. Immunol
, vol.196
, pp. 596-606
-
-
Lao, M.1
Shi, M.2
Zou, Y.3
Huang, M.4
Ye, Y.5
Qiu, Q.6
Xiao, Y.7
Zeng, S.8
Liang, L.9
Yang, X.10
-
54
-
-
84873268186
-
PUMA, a critical mediator of cell death—One decade on from its discovery
-
Hikisz, P.; Kiliańska, Z.M. PUMA, a critical mediator of cell death—One decade on from its discovery. Cell. Mol. Biol. Lett. 2012, 17, 646–669. [CrossRef] [PubMed]
-
(2012)
Cell. Mol. Biol. Lett.
, vol.17
, pp. 646-669
-
-
Hikisz, P.1
Kiliańska, Z.M.2
-
55
-
-
2442559290
-
Receptor-interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (C-IAP1 and c-IAP2) in vitro
-
Park, S.M.; Yoon, J.B.; Lee, T.H. Receptor-interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro. FEBS Lett. 2001, 566, 151–156. [CrossRef] [PubMed]
-
(2001)
FEBS Lett.
, vol.566
, pp. 151-156
-
-
Park, S.M.1
Yoon, J.B.2
Lee, T.H.3
-
56
-
-
84867877809
-
NFκB and ubquitination: Partners in disarming RIPK1-mediated cell death
-
O’Donnell, M.A.; Ting, A.T. NFκB and ubquitination: Partners in disarming RIPK1-mediated cell death. Immunol. Res. 2012, 54, 214–226. [CrossRef] [PubMed]
-
(2012)
Immunol. Res
, vol.54
, pp. 214-226
-
-
O’Donnell, M.A.1
Ting, A.T.2
-
57
-
-
84929512041
-
RIPK1 and RIPK3: Critical regulators of inflammation and cell death
-
Newton, K. RIPK1 and RIPK3: Critical regulators of inflammation and cell death. Trends Cell Biol. 2015, 25, 347–353. [CrossRef] [PubMed]
-
(2015)
Trends Cell Biol
, vol.25
, pp. 347-353
-
-
Newton, K.1
-
58
-
-
84931377023
-
The diverse role of RIP kinases in necropotosis and inflammation
-
Silke, J.; Rickard, J.A.; Gerlic, M. The diverse role of RIP kinases in necropotosis and inflammation. Nat. Immunol. 2015, 16, 689–697. [CrossRef] [PubMed]
-
(2015)
Nat. Immunol
, vol.16
, pp. 689-697
-
-
Silke, J.1
Rickard, J.A.2
Gerlic, M.3
-
59
-
-
84920770936
-
Programmed necrosis and necroptosis signalling
-
Feoktistova, M.; Leverkus, M. Programmed necrosis and necroptosis signalling. FEBS J. 2015, 282, 19–31. [CrossRef] [PubMed]
-
(2015)
FEBS J
, vol.282
, pp. 19-31
-
-
Feoktistova, M.1
Leverkus, M.2
-
60
-
-
84949537573
-
Characterization of the RIPK3-mediated phosphorylation of the activation loop of MLML during necroptosis
-
Rodriguez, D.A.; Weinlich, R.; Brown, S.; Guy, C.; Fitzgerald, P.; Dillon, C.P.; Oberst, A.; Quarato, G.; Low, J.; Cripps, J.G.; et al. Characterization of the RIPK3-mediated phosphorylation of the activation loop of MLML during necroptosis. Cell Death Differ. 2016, 23, 76–88. [CrossRef] [PubMed]
-
(2016)
Cell Death Differ
, vol.23
, pp. 76-88
-
-
Rodriguez, D.A.1
Weinlich, R.2
Brown, S.3
Guy, C.4
Fitzgerald, P.5
Dillon, C.P.6
Oberst, A.7
Quarato, G.8
Low, J.9
Cripps, J.G.10
-
61
-
-
84931055813
-
Linear ubiquitination signals in adaptive immune responses
-
Ikeda, F. Linear ubiquitination signals in adaptive immune responses. Immunol. Rev. 2015, 266, 222–236. [CrossRef] [PubMed]
-
(2015)
Immunol. Rev
, vol.266
, pp. 222-236
-
-
Ikeda, F.1
-
62
-
-
85014097157
-
Correction of dysfunctional apoptosis in arthritis by pharmacologic interventions: Focus on altering the activity of inhibitor of apoptosis protein
-
Pandalai, S.G., Ed.; Research Signpost: Kerala, India
-
Lewis, A.C.; Malemud, C.J. Correction of dysfunctional apoptosis in arthritis by pharmacologic interventions: Focus on altering the activity of inhibitor of apoptosis protein. In Recent Research Developments in Pharmacology; Pandalai, S.G., Ed.; Research Signpost: Kerala, India, 2011; pp. 69–84.
-
(2011)
Recent Research Developments in Pharmacology
, pp. 69-84
-
-
Lewis, A.C.1
Malemud, C.J.2
-
63
-
-
47849083565
-
A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases
-
Abhari, B.A.; Davoodi, J. A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases. J. Mol. Biol. 2008, 381, 645–654. [CrossRef] [PubMed]
-
(2008)
J. Mol. Biol
, vol.381
, pp. 645-654
-
-
Abhari, B.A.1
Davoodi, J.2
-
64
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen, A.M.; Ekert, P.G.; Pakusch, M.; Silke, J.; Connolly, Y.; Reid, G.E.; Moritz, R.L.; Simpson, R.J.; Vaux, D.L.; et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000, 102, 43–53. [CrossRef]
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, Y.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
65
-
-
60849126397
-
Elevated expression of caspase-3 inhibitors, survivin, and xIAP correlates with low levels of apoptosis in active rheumatoid arthritis
-
Dharmapatni, A.A.; Smith, M.D.; Findlay, D.M.; Holding, C.A.; Evdokiou, A.; Ahern, M.J.; Weedon, H.; Chen, P.; Screaton, G.; Xu, X.N.; et al. Elevated expression of caspase-3 inhibitors, survivin, and xIAP correlates with low levels of apoptosis in active rheumatoid arthritis. Arthritis Res. Ther. 2009, 11, R13. [CrossRef] [PubMed]
-
(2009)
Arthritis Res. Ther.
, vol.11
, pp. R13
-
-
Dharmapatni, A.A.1
Smith, M.D.2
Findlay, D.M.3
Holding, C.A.4
Evdokiou, A.5
Ahern, M.J.6
Weedon, H.7
Chen, P.8
Screaton, G.9
Xu, X.N.10
-
66
-
-
84939825981
-
The X-linked inhibitor of apoptosis protein inhibitor embelin suppresses inflammation and bone erosion in collagen-antibody-induced arthritis mice
-
Dharmapatni, A.A.; Cantley, M.D.; Marino, V.; Perilli, E.; Crotti, T.N.; Smith, M.D.; Haynes, D.R. The X-linked inhibitor of apoptosis protein inhibitor embelin suppresses inflammation and bone erosion in collagen-antibody-induced arthritis mice. Mediat. Inflamm. 2015, 2015, 564042. [CrossRef] [PubMed]
-
(2015)
Mediat. Inflamm.
, vol.2015
-
-
Dharmapatni, A.A.1
Cantley, M.D.2
Marino, V.3
Perilli, E.4
Crotti, T.N.5
Smith, M.D.6
Haynes, D.R.7
-
67
-
-
84923674191
-
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
-
Lawlor, K.E.; Khan, N.; Mildenhall, A.; Gerlic, M.; Croker, B.A.; D’Cruz, A.A.; Hall, C.; Kaur, S.S.; Anderton, H.; Masters, S.L.; et al. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat. Commun. 2015, 6, 6282. [CrossRef] [PubMed]
-
(2015)
Nat. Commun
, vol.6
, pp. 6282
-
-
Lawlor, K.E.1
Khan, N.2
Mildenhall, A.3
Gerlic, M.4
Croker, B.A.5
D’Cruz, A.A.6
Hall, C.7
Kaur, S.S.8
Anderton, H.9
Masters, S.L.10
-
68
-
-
84903480849
-
XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation
-
Yabal, M.; Müller, N.; Adler, H.; Knies, N.; Groß, C.J.; Damgaard, R.B.; Kanegane, H.; Ringelhan, M.; Kaufmann, T.; Heikenwälder, M.; et al. XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation. Cell Rep. 2014, 7, 1796–1808. [CrossRef] [PubMed]
-
(2014)
Cell Rep
, vol.7
, pp. 1796-1808
-
-
Yabal, M.1
Müller, N.2
Adler, H.3
Knies, N.4
Groß, C.J.5
Damgaard, R.B.6
Kanegane, H.7
Ringelhan, M.8
Kaufmann, T.9
Heikenwälder, M.10
-
69
-
-
84921281866
-
MTOR signaling in T cell immunity and autoimmunity
-
Liu, Y.; Zhang, D.T.; Liu, X.G. mTOR signaling in T cell immunity and autoimmunity. Int. Rev. Immunol. 2015, 34, 50–66. [CrossRef] [PubMed]
-
(2015)
Int. Rev. Immunol
, vol.34
, pp. 50-66
-
-
Liu, Y.1
Zhang, D.T.2
Liu, X.G.3
-
70
-
-
52149104245
-
XIAP regulates bi-phasic NF-κB induction involving physical interaction and ubiquitination of MEKK2
-
Winsauer, G.; Resch, U.; Hofer-Warbinek, R.; Schichi, Y.M.; de Martin, R. XIAP regulates bi-phasic NF-κB induction involving physical interaction and ubiquitination of MEKK2. Cell Signal. 2008, 20, 2107–2112. [CrossRef] [PubMed]
-
(2008)
Cell Signal
, vol.20
, pp. 2107-2112
-
-
Winsauer, G.1
Resch, U.2
Hofer-Warbinek, R.3
Schichi, Y.M.4
De Martin, R.5
-
71
-
-
84872462277
-
The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy
-
De Almagro, M.C.; Vucic, D. The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy. Exp. Oncol. 2012, 34, 200–211. [PubMed]
-
(2012)
Exp. Oncol.
, vol.34
, pp. 200-211
-
-
De Almagro, M.C.1
Vucic, D.2
-
72
-
-
85007097600
-
Chondrocyte apoptosis in rheumatoid arthritis: Is preventive therapy possible?
-
Malemud, C.J. Chondrocyte apoptosis in rheumatoid arthritis: Is preventive therapy possible? Immunotherapy 2015, 1, 102. [CrossRef] [PubMed]
-
(2015)
Immunotherapy
, vol.1
, pp. 102
-
-
Malemud, C.J.1
|