메뉴 건너뛰기




Volumn 11, Issue 1, 2009, Pages

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 3 INHIBITOR; SURVIVIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; X LINKED INHIBITOR OF APOPTOSIS; BIRC5 PROTEIN, HUMAN; ENZYME INHIBITOR; MICROTUBULE ASSOCIATED PROTEIN; XIAP PROTEIN, HUMAN;

EID: 60849126397     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2603     Document Type: Article
Times cited : (52)

References (50)
  • 1
    • 33644842150 scopus 로고    scopus 로고
    • Tumor necrosis factor ligand-receptor superfamily and arthritis
    • 16394654
    • Hsu HC Wu Y Mountz JD Tumor necrosis factor ligand-receptor superfamily and arthritis Curr Dir Autoimmun 2006, 9:37-54. 16394654
    • (2006) Curr Dir Autoimmun , vol.9 , pp. 37-54
    • Hsu, H.C.1    Wu, Y.2    Mountz, J.D.3
  • 2
    • 0030809950 scopus 로고    scopus 로고
    • Apoptosis in the rheumatic diseases
    • 10.1002/art.1780401102 9365079
    • Vaishnaw AK McNally JD Elkon KB Apoptosis in the rheumatic diseases Arthritis Rheum 1997, 40:1917-1927 10.1002/art.1780401102 9365079
    • (1997) Arthritis Rheum , vol.40 , pp. 1917-1927
    • Vaishnaw, A.K.1    McNally, J.D.2    Elkon, K.B.3
  • 5
    • 85047697089 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells
    • 10.1038/sj.onc.1205151 11850832
    • Nesterov A Ivashchenko Y Kraft AS Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells Oncogene 2002, 21:1135-1140. 10.1038/sj.onc.1205151 11850832
    • (2002) Oncogene , vol.21 , pp. 1135-1140
    • Nesterov, A.1    Ivashchenko, Y.2    Kraft, A.S.3
  • 6
    • 0036384168 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in human articular chondrocytes in vitro
    • 10.1016/S0006-291X(02)00916-6 12176034
    • Pettersen I Figenschau Y Olsen E Bakkelund W Smedsrod B Sveinbjornsson B Tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in human articular chondrocytes in vitro Biochem Biophys Res Commun 2002, 296:671-676. 10.1016/S0006-291X(02)00916-6 12176034
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 671-676
    • Pettersen, I.1    Figenschau, Y.2    Olsen, E.3    Bakkelund, W.4    Smedsrod, B.5    Sveinbjornsson, B.6
  • 7
    • 33645011088 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) regulates endothelial nitric oxide synthase (eNOS) activity and its localization within the human vein endothelial cells (HUVEC) in culture
    • 16229016 10.1002/jcb.20686
    • Di Pietro R Mariggio MA Guarnieri S Sancilio S Giardinelli A Di Silvestre S Consoli A Zauli G Pandolfi A Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) regulates endothelial nitric oxide synthase (eNOS) activity and its localization within the human vein endothelial cells (HUVEC) in culture J Cell Biochem 2006, 97:782-794. 16229016 10.1002/jcb.20686
    • (2006) J Cell Biochem , vol.97 , pp. 782-794
    • Di Pietro, R.1    Mariggio, M.A.2    Guarnieri, S.3    Sancilio, S.4    Giardinelli, A.5    Di Silvestre, S.6    Consoli, A.7    Zauli, G.8    Pandolfi, A.9
  • 9
    • 16644372319 scopus 로고    scopus 로고
    • Following a TRAIL: Update on a ligand and its five receptors
    • 10.1038/sj.cr.7290236 15538968
    • Kimberley FC Screaton GR Following a TRAIL: Update on a ligand and its five receptors Cell Res 2004, 14:359-372. 10.1038/sj.cr.7290236 15538968
    • (2004) Cell Res , vol.14 , pp. 359-372
    • Kimberley, F.C.1    Screaton, G.R.2
  • 11
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • 9743343
    • Griffith TS Chin WA Jackson GC Lynch DH Kubin MZ Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells J Immunol 1998, 161:2833-2840. 9743343
    • (1998) J Immunol , vol.161 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3    Lynch, D.H.4    Kubin, M.Z.5
  • 12
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • 10.1038/40901 9230442
    • Deveraux QL Takahashi R Salvesen GS Reed JC X-linked IAP is a direct inhibitor of cell-death proteases Nature 1997, 388:300-304. 10.1038/ 40901 9230442
    • (1997) Nature , vol.388 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 13
    • 0036605042 scopus 로고    scopus 로고
    • Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis
    • 10.1002/ijc.10376 11992538
    • Evdokiou A Bouralexis S Atkins GJ Chai F Hay S Clayer M Findlay DM Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis Int J Cancer 2002, 99:491-504. 10.1002/ijc.10376 11992538
    • (2002) Int J Cancer , vol.99 , pp. 491-504
    • Evdokiou, A.1    Bouralexis, S.2    Atkins, G.J.3    Chai, F.4    Hay, S.5    Clayer, M.6    Findlay, D.M.7
  • 14
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • 10.1016/S1074-7613(00)80399-4 9430226
    • Degli-Esposti MA Dougall WC Smolak PJ Waugh JY Smith CA Goodwin RG The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain Immunity 1997, 7:813-820. 10.1016/S1074-7613(00)80399-4 9430226
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 15
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • 10364001
    • Zhang XD Franco A Myers K Gray C Nguyen T Hersey P Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma Cancer Res 1999, 59:2747-2753. 10364001
    • (1999) Cancer Res , vol.59 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6
  • 16
    • 0037672290 scopus 로고    scopus 로고
    • Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas
    • 10.1002/path.1364 12845629
    • Koornstra JJ Kleibeuker JH van Geelen CM Rijcken FE Hollema H de Vries EG de Jong S Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas J Pathol 2003, 200:327-335. 10.1002/path.1364 12845629
    • (2003) J Pathol , vol.200 , pp. 327-335
    • Koornstra, J.J.1    Kleibeuker, J.H.2    van Geelen, C.M.3    Rijcken, F.E.4    Hollema, H.5    de Vries, E.G.6    de Jong, S.7
  • 17
    • 0034599757 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression
    • 2193179 10748228 10.1084/jem.191.7.1095
    • Song K Chen Y Goke R Wilmen A Seidel C Goke A Hilliard B Chen Y Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression J Exp Med 2000, 191:1095-1104. 2193179 10748228 10.1084/jem.191.7.1095
    • (2000) J Exp Med , vol.191 , pp. 1095-1104
    • Song, K.1    Chen, Y.2    Goke, R.3    Wilmen, A.4    Seidel, C.5    Goke, A.6    Hilliard, B.7    Chen, Y.8
  • 19
    • 4444371352 scopus 로고    scopus 로고
    • Rheumatoid arthritis synovial fluid fibroblasts express TRAIL-R2 (DR5) that is functionally active
    • 10.1002/art.20501 15457446
    • Miranda-Carus ME Balsa A Benito-Miguel M De Ayala CP Martin-Mola E Rheumatoid arthritis synovial fluid fibroblasts express TRAIL-R2 (DR5) that is functionally active Arthritis Rheum 2004, 50:2786-2793. 10.1002/ art.20501 15457446
    • (2004) Arthritis Rheum , vol.50 , pp. 2786-2793
    • Miranda-Carus, M.E.1    Balsa, A.2    Benito-Miguel, M.3    De Ayala, C.P.4    Martin-Mola, E.5
  • 20
    • 3543012048 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells
    • 1809120 15270863 10.1111/j.1365-2249.2004.02534.x
    • Miyashita T Kawakami A Nakashima T Yamasaki S Tamai M Tanaka F Kamachi M Ida H Migita K Origuchi T Nakao K Eguchi K Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells Clin Exp Immunol 2004, 137:430-436. 1809120 15270863 10.1111/j.1365-2249.2004.02534.x
    • (2004) Clin Exp Immunol , vol.137 , pp. 430-436
    • Miyashita, T.1    Kawakami, A.2    Nakashima, T.3    Yamasaki, S.4    Tamai, M.5    Tanaka, F.6    Kamachi, M.7    Ida, H.8    Migita, K.9    Origuchi, T.10    Nakao, K.11    Eguchi, K.12
  • 21
    • 18144416502 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt
    • 10.1074/jbc.M414469200 15684417
    • Morel J Audo R Hahne M Combe B Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt J Biol Chem 2005, 280:15709-15718. 10.1074/jbc.M414469200 15684417
    • (2005) J Biol Chem , vol.280 , pp. 15709-15718
    • Morel, J.1    Audo, R.2    Hahne, M.3    Combe, B.4
  • 24
    • 0032528419 scopus 로고    scopus 로고
    • Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28- T cells from rheumatoid arthritis patients
    • 9670983
    • Schirmer M Vallejo AN Weyand CM Goronzy JJ Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28- T cells from rheumatoid arthritis patients J Immunol 1998, 161:1018-1025. 9670983
    • (1998) J Immunol , vol.161 , pp. 1018-1025
    • Schirmer, M.1    Vallejo, A.N.2    Weyand, C.M.3    Goronzy, J.J.4
  • 25
    • 25444484909 scopus 로고    scopus 로고
    • Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis
    • 1065333 15743483 10.1186/ar1498
    • Bokarewa M Lindblad S Bokarew D Tarkowski A Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis Arthritis Res Ther 2005, 7:R349-358. 1065333 15743483 10.1186/ar1498
    • (2005) Arthritis Res Ther , vol.7
    • Bokarewa, M.1    Lindblad, S.2    Bokarew, D.3    Tarkowski, A.4
  • 27
    • 0242579588 scopus 로고    scopus 로고
    • Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3
    • 10.1002/art.11302 14613271
    • Perlman H Nguyen N Liu H Eslick J Esser S Walsh K Moore TL Pope RM Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3 Arthritis Rheum 2003, 48:3096-3101. 10.1002/art.11302 14613271
    • (2003) Arthritis Rheum , vol.48 , pp. 3096-3101
    • Perlman, H.1    Nguyen, N.2    Liu, H.3    Eslick, J.4    Esser, S.5    Walsh, K.6    Moore, T.L.7    Pope, R.M.8
  • 30
    • 0026003027 scopus 로고
    • The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy
    • 10.1002/art.1780341003 1930310
    • Dougados M Linden van der S Juhlin R Huitfeldt B Amor B Calin A Cats A Dijkmans B Olivieri I Pasero G et al The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy Arthritis Rheum 1991, 34:1218-1227. 10.1002/ art.1780341003 1930310
    • (1991) Arthritis Rheum , vol.34 , pp. 1218-1227
    • Dougados, M.1    Linden, S.2    Juhlin, R.3    Huitfeldt, B.4    Amor, B.5    Calin, A.6    Cats, A.7    Dijkmans, B.8    Olivieri, I.9    Pasero, G.10
  • 31
    • 28844455579 scopus 로고    scopus 로고
    • Characterisation of monoclonal antibodies to the TNF and TNF receptor families
    • 10.1016/j.cellimm.2005.08.010 16157320
    • Ch'en PF Xu XG Liu XS Liu Y Song CJ Screaton GR Jin BQ Xu XN Characterisation of monoclonal antibodies to the TNF and TNF receptor families Cell Immunol 2005, 236:78-85. 10.1016/j.cellimm.2005.08.010 16157320
    • (2005) Cell Immunol , vol.236 , pp. 78-85
    • Ch'en, P.F.1    Xu, X.G.2    Liu, X.S.3    Liu, Y.4    Song, C.J.5    Screaton, G.R.6    Jin, B.Q.7    Xu, X.N.8
  • 33
    • 0026551539 scopus 로고
    • Immunohistochemical analysis of synovial membranes from inflammatory and non-inflammatory arthritides: Scarcity of CD5 positive B cells and IL2 receptor bearing T cells
    • 10.3109/00313029209063615 1374550
    • Smith MD O'Donnell J Highton J Palmer DG Rozenbilds M Roberts-Thomson PJ Immunohistochemical analysis of synovial membranes from inflammatory and non-inflammatory arthritides: Scarcity of CD5 positive B cells and IL2 receptor bearing T cells Pathology 1992, 24:19-26. 10.3109/ 00313029209063615 1374550
    • (1992) Pathology , vol.24 , pp. 19-26
    • Smith, M.D.1    O'Donnell, J.2    Highton, J.3    Palmer, D.G.4    Rozenbilds, M.5    Roberts-Thomson, P.J.6
  • 34
    • 0036892685 scopus 로고    scopus 로고
    • Receptor activator NF-kappaB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: Semiquantitative and quantitative analysis
    • 1753975 12429533 10.1136/ard.61.12.1047
    • Crotti TN Smith MD Weedon H Ahern MJ Findlay DM Kraan M Tak PP Haynes DR Receptor activator NF-kappaB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: Semiquantitative and quantitative analysis Ann Rheum Dis 2002, 61:1047-1054. 1753975 12429533 10.1136/ard.61.12.1047
    • (2002) Ann Rheum Dis , vol.61 , pp. 1047-1054
    • Crotti, T.N.1    Smith, M.D.2    Weedon, H.3    Ahern, M.J.4    Findlay, D.M.5    Kraan, M.6    Tak, P.P.7    Haynes, D.R.8
  • 36
    • 28244432181 scopus 로고    scopus 로고
    • Expression of apoptosome pathway-related transcripts in non-small cell lung cancer
    • 10.1007/s00432-005-0048-6 16231180
    • Krepela E Prochazka J Fiala P Zatloukal P Selinger P Expression of apoptosome pathway-related transcripts in non-small cell lung cancer J Cancer Res Clin Oncol 2006, 132:57-68. 10.1007/s00432-005-0048-6 16231180
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 57-68
    • Krepela, E.1    Prochazka, J.2    Fiala, P.3    Zatloukal, P.4    Selinger, P.5
  • 38
    • 34247381025 scopus 로고    scopus 로고
    • Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy
    • 10.1002/ijc.22554 17311258
    • Lopes RB Gangeswaran R McNeish IA Wang Y Lemoine NR Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy Int J Cancer 2007, 120:2344-2352. 10.1002/ijc.22554 17311258
    • (2007) Int J Cancer , vol.120 , pp. 2344-2352
    • Lopes, R.B.1    Gangeswaran, R.2    McNeish, I.A.3    Wang, Y.4    Lemoine, N.R.5
  • 39
    • 12944250863 scopus 로고    scopus 로고
    • Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis
    • 10.1111/j.0022-202X.2004.23612.x 15675957
    • Franssen ME Zeeuwen PL Vierwinden G Kerkhof van de PC Schalkwijk J van Erp PE Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis J Invest Dermatol 2005, 124:373-383. 10.1111/j.0022-202X.2004.23612.x 15675957
    • (2005) J Invest Dermatol , vol.124 , pp. 373-383
    • Franssen, M.E.1    Zeeuwen, P.L.2    Vierwinden, G.3    Kerkhof, P.C.4    Schalkwijk, J.5    van Erp, P.E.6
  • 40
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • 10.1006/meth.2001.1262 11846609
    • Livak KJ Schmittgen TD Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 2001, 25:402-408. 10.1006/meth.2001.1262 11846609
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 41
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in cancer
    • 10.1038/sj.cgt.7700792 15550937
    • Zhang L Fang B Mechanisms of resistance to TRAIL-induced apoptosis in cancer Cancer Gene Ther 2005, 12:228-237. 10.1038/sj.cgt.7700792 15550937
    • (2005) Cancer Gene Ther , vol.12 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 43
    • 0033974084 scopus 로고    scopus 로고
    • Molecular determinants of response to TRAIL in killing of normal and cancer cells
    • 10690508
    • Kim K Fisher MJ Xu SQ el-Deiry WS Molecular determinants of response to TRAIL in killing of normal and cancer cells Clin Cancer Res 2000, 6:335-346. 10690508
    • (2000) Clin Cancer Res , vol.6 , pp. 335-346
    • Kim, K.1    Fisher, M.J.2    Xu, S.Q.3    el-Deiry, W.S.4
  • 46
    • 0000005230 scopus 로고    scopus 로고
    • Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells
    • 10754286
    • Zhang XD Franco AV Nguyen T Gray CP Hersey P Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells J Immunol 2000, 164:3961-3970. 10754286
    • (2000) J Immunol , vol.164 , pp. 3961-3970
    • Zhang, X.D.1    Franco, A.V.2    Nguyen, T.3    Gray, C.P.4    Hersey, P.5
  • 47
    • 0035031889 scopus 로고    scopus 로고
    • Treatment-induced remission in rheumatoid arthritis patients is characterized by a reduction in macrophage content of synovial biopsies
    • 10.1093/rheumatology/40.4.367 11312372
    • Smith MD Kraan MC Slavotinek J Au V Weedon H Parker A Coleman M Roberts-Thomson PJ Ahern MJ Treatment-induced remission in rheumatoid arthritis patients is characterized by a reduction in macrophage content of synovial biopsies Rheumatology (Oxford) 2001, 40:367-374. 10.1093/ rheumatology/40.4.367 11312372
    • (2001) Rheumatology (Oxford) , vol.40 , pp. 367-374
    • Smith, M.D.1    Kraan, M.C.2    Slavotinek, J.3    Au, V.4    Weedon, H.5    Parker, A.6    Coleman, M.7    Roberts-Thomson, P.J.8    Ahern, M.J.9
  • 49
    • 0034700491 scopus 로고    scopus 로고
    • Structural basis of IAP recognition by Smac/DIABLO
    • 10.1038/35050012 11140638
    • Wu G Chai J Suber TL Wu JW Du C Wang X Shi Y Structural basis of IAP recognition by Smac/DIABLO Nature 2000, 408:1008-1012. 10.1038/35050012 11140638
    • (2000) Nature , vol.408 , pp. 1008-1012
    • Wu, G.1    Chai, J.2    Suber, T.L.3    Wu, J.W.4    Du, C.5    Wang, X.6    Shi, Y.7
  • 50
    • 0036786268 scopus 로고    scopus 로고
    • Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium
    • 1753901 12228167 10.1136/ard.61.10.934
    • Catrina AI Ulfgren AK Lindblad S Grondal L Klareskog L Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium Ann Rheum Dis 2002, 61:934-936. 1753901 12228167 10.1136/ ard.61.10.934
    • (2002) Ann Rheum Dis , vol.61 , pp. 934-936
    • Catrina, A.I.1    Ulfgren, A.K.2    Lindblad, S.3    Grondal, L.4    Klareskog, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.