-
1
-
-
0032575750
-
Caspases: enemies within
-
Thornberry N.A., and Lazebnik Y. Caspases: enemies within. Science 281 (1998) 1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
2
-
-
0032575714
-
Death receptors: signaling and modulation
-
Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Science 281 (1998) 1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
3
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior P., and Salvesen G.S. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 384 (2004) 201-232
-
(2004)
Biochem. J.
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
4
-
-
0030702084
-
Caspases: intracellular signaling by proteolysis
-
Salvesen G.S., and Dixit V.M. Caspases: intracellular signaling by proteolysis. Cell 91 (1997) 443-446
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
5
-
-
0032562661
-
Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits
-
Srinivasula S.M., Ahmad M., MacFarlane M., Luo Z., Huang Z., Fernandes-Alnemri T., and Alnemri E.S. Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits. J. Biol. Chem. 273 (1998) 10107-10111
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10107-10111
-
-
Srinivasula, S.M.1
Ahmad, M.2
MacFarlane, M.3
Luo, Z.4
Huang, Z.5
Fernandes-Alnemri, T.6
Alnemri, E.S.7
-
6
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388 (1997) 300-304
-
(1997)
Nature
, vol.388
, pp. 300-304
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
7
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N., Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16 (1997) 6914-6925
-
(1997)
EMBO J.
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
-
8
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Cherton-Horvat G., et al. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 379 (1996) 349-353
-
(1996)
Nature
, vol.379
, pp. 349-353
-
-
Liston, P.1
Roy, N.2
Tamai, K.3
Lefebvre, C.4
Baird, S.5
Cherton-Horvat, G.6
-
9
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki E.N., Chai J., Rigotti D.J., Riedl S.J., Li P., Srinivasula S.M., et al. Mechanism of XIAP-mediated inhibition of caspase-9. Mol. Cell 11 (2003) 519-527
-
(2003)
Mol. Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
Srinivasula, S.M.6
-
10
-
-
0035831021
-
Structural basis of caspase-7 inhibition by XIAP
-
Chai J., Shiozaki E., Srinivasula S.M., Wu Q., Datta P., Alnemri E.S., and Shi Y. Structural basis of caspase-7 inhibition by XIAP. Cell 104 (2001) 769-780
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.1
Shiozaki, E.2
Srinivasula, S.M.3
Wu, Q.4
Datta, P.5
Alnemri, E.S.6
Shi, Y.7
-
11
-
-
0035831022
-
Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
-
Huang Y., Park Y.C., Rich R.L., Segal D., Myszka D.G., and Wu H. Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain. Cell 104 (2001) 781-790
-
(2001)
Cell
, vol.104
, pp. 781-790
-
-
Huang, Y.1
Park, Y.C.2
Rich, R.L.3
Segal, D.4
Myszka, D.G.5
Wu, H.6
-
12
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C., Fang M., Li Y., Li L., and Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102 (2000) 33-42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
13
-
-
0344348821
-
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
-
Hu Y., Benedict M.A., Ding L., and Nunez G. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J. 18 (1999) 3586-3595
-
(1999)
EMBO J.
, vol.18
, pp. 3586-3595
-
-
Hu, Y.1
Benedict, M.A.2
Ding, L.3
Nunez, G.4
-
14
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91 (1997) 479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
15
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J., Du C., Wu J.W., Kyin S., Wang X., and Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 406 (2000) 855-862
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
16
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
-
Srinivasula S.M., Hegde R., Saleh A., Datta P., Shiozaki E., Chai J., et al. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature 410 (2001) 112-116
-
(2001)
Nature
, vol.410
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
-
17
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
Riedl S.J., Renatus M., Schwarzenbacher R., Zhou Q., Sun C., Fesik S.W., et al. Structural basis for the inhibition of caspase-3 by XIAP. Cell 104 (2001) 791-800
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, C.5
Fesik, S.W.6
-
18
-
-
1642512653
-
Antagonizing XIAP-mediated caspase-3 inhibition, Achilles' heel of cancers?
-
Huang Y., Lu M., and Wu H. Antagonizing XIAP-mediated caspase-3 inhibition, Achilles' heel of cancers?. Cancer Cell 5 (2004) 1-2
-
(2004)
Cancer Cell
, vol.5
, pp. 1-2
-
-
Huang, Y.1
Lu, M.2
Wu, H.3
-
19
-
-
1542782158
-
Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac
-
Huang Y., Rich R.L., Myszka D.G., and Wu H. Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac. J. Biol. Chem. 278 (2003) 49517-49522
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49517-49522
-
-
Huang, Y.1
Rich, R.L.2
Myszka, D.G.3
Wu, H.4
-
20
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl S.J., and Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell Biol. 5 (2004) 897-907
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
21
-
-
4644323252
-
Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9
-
Davoodi J., Lin L., Kelly J., Liston P., and MacKenzie A.E. Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9. J. Biol. Chem. 279 (2004) 40622-40628
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40622-40628
-
-
Davoodi, J.1
Lin, L.2
Kelly, J.3
Liston, P.4
MacKenzie, A.E.5
-
23
-
-
35648961848
-
A dimeric Smac/DIABLO peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/DIABLO
-
Gao Z., Tian Y., Wang J., Yin Q., Wu H., Li Y.M., and Jiang X. A dimeric Smac/DIABLO peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/DIABLO. J. Biol. Chem. 282 (2007) 30718-30727
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30718-30727
-
-
Gao, Z.1
Tian, Y.2
Wang, J.3
Yin, Q.4
Wu, H.5
Li, Y.M.6
Jiang, X.7
-
24
-
-
0035807966
-
Dimer formation drives the activation of the cell death protease caspase 9
-
Renatus M., Stennicke H.R., Scott F.L., Liddington R.C., and Salvesen G.S. Dimer formation drives the activation of the cell death protease caspase 9. Proc. Natl Acad. Sci. USA 98 (2001) 14250-14255
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14250-14255
-
-
Renatus, M.1
Stennicke, H.R.2
Scott, F.L.3
Liddington, R.C.4
Salvesen, G.S.5
-
25
-
-
0033592470
-
NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
-
Sun C., Cai M., Gunasekera A.H., Meadows R.P., Wang H., Chen J., et al. NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP. Nature 401 (1999) 818-822
-
(1999)
Nature
, vol.401
, pp. 818-822
-
-
Sun, C.1
Cai, M.2
Gunasekera, A.H.3
Meadows, R.P.4
Wang, H.5
Chen, J.6
-
26
-
-
0035920126
-
X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes
-
Suzuki Y., Nakabayashi Y., Nakata K., Reed J.C., and Takahashi R. X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes. J. Biol. Chem. 276 (2001) 27058-27063
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27058-27063
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Nakata, K.3
Reed, J.C.4
Takahashi, R.5
-
27
-
-
4444243683
-
A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
-
Li L., Thomas R.M., Suzuki H., De Brabander J.K., Wang X., and Harran P.G. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 305 (2004) 1471-1474
-
(2004)
Science
, vol.305
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
28
-
-
14844323968
-
XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs
-
Scott F.L., Denault J.B., Riedl S.J., Shin H., Renatus M., and Salvesen G.S. XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs. EMBO J. 24 (2005) 645-655
-
(2005)
EMBO J.
, vol.24
, pp. 645-655
-
-
Scott, F.L.1
Denault, J.B.2
Riedl, S.J.3
Shin, H.4
Renatus, M.5
Salvesen, G.S.6
-
29
-
-
0033215040
-
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
-
Deveraux Q.L., Leo E., Stennicke H.R., Welsh K., Salvesen G.S., and Reed J.C. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. EMBO J. 18 (1999) 5242-5251
-
(1999)
EMBO J.
, vol.18
, pp. 5242-5251
-
-
Deveraux, Q.L.1
Leo, E.2
Stennicke, H.R.3
Welsh, K.4
Salvesen, G.S.5
Reed, J.C.6
-
30
-
-
0037088904
-
The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7
-
Maier J.K., Lahoua Z., Gendron N.H., Fetni R., Johnston A., Davoodi J., et al. The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7. J. Neurosci. 22 (2002) 2035-2043
-
(2002)
J. Neurosci.
, vol.22
, pp. 2035-2043
-
-
Maier, J.K.1
Lahoua, Z.2
Gendron, N.H.3
Fetni, R.4
Johnston, A.5
Davoodi, J.6
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