메뉴 건너뛰기




Volumn 153, Issue , 2017, Pages 208-219

Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC)

Author keywords

Anticancer; Bioavailability; Honokiol; Nanomicellar formulation; TNBC

Indexed keywords

ANIMALS; CELL DEATH; CHEMOTHERAPY; DISEASES; FINITE DIFFERENCE METHOD; TUMORS;

EID: 85013784542     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2017.01.038     Document Type: Article
Times cited : (57)

References (52)
  • 1
    • 84938748194 scopus 로고    scopus 로고
    • Therapeutic targets of triple-negative breast cancer: a review
    • [1] Jamdade, V.S., et al. Therapeutic targets of triple-negative breast cancer: a review. Br. J. Pharmacol. 172:17 (2015), 4228–4237.
    • (2015) Br. J. Pharmacol. , vol.172 , Issue.17 , pp. 4228-4237
    • Jamdade, V.S.1
  • 3
    • 84874376997 scopus 로고    scopus 로고
    • Molecular characterization of basal-like and non-basal-like triple-negative breast cancer
    • [3] Prat, A., et al. Molecular characterization of basal-like and non-basal-like triple-negative breast cancer. Oncologist 18:2 (2013), 123–133.
    • (2013) Oncologist , vol.18 , Issue.2 , pp. 123-133
    • Prat, A.1
  • 4
    • 84897484868 scopus 로고    scopus 로고
    • Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid
    • [4] Godugu, C., et al. Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid. PLoS One, 9(3), 2014, e89919.
    • (2014) PLoS One , vol.9 , Issue.3 , pp. e89919
    • Godugu, C.1
  • 5
    • 67650675111 scopus 로고    scopus 로고
    • Impact of Natural products on developing new anti-cancer agents†
    • [5] Cragg, G.M., Grothaus, P.G., Newman, D.J., Impact of Natural products on developing new anti-cancer agents†. Chem. Rev. 109:7 (2009), 3012–3043.
    • (2009) Chem. Rev. , vol.109 , Issue.7 , pp. 3012-3043
    • Cragg, G.M.1    Grothaus, P.G.2    Newman, D.J.3
  • 6
    • 77956016499 scopus 로고    scopus 로고
    • Cancer prevention with natural compounds
    • Elsevier
    • [6] Gullett, N.P., et al. Cancer prevention with natural compounds. Seminars in Oncology, 2010, Elsevier.
    • (2010) Seminars in Oncology
    • Gullett, N.P.1
  • 7
    • 66849095259 scopus 로고    scopus 로고
    • Perspectives for cancer prevention with natural compounds
    • [7] Amin, A.R., et al. Perspectives for cancer prevention with natural compounds. J. Clin. Oncol. 27:16 (2009), 2712–2725.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.16 , pp. 2712-2725
    • Amin, A.R.1
  • 8
    • 64749084915 scopus 로고    scopus 로고
    • Honokiol, a multifunctional antiangiogenic and antitumor agent
    • [8] Fried, L.E., Arbiser, J.L., Honokiol, a multifunctional antiangiogenic and antitumor agent. Antioxid. Redox Signal. 11:5 (2009), 1139–1148.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.5 , pp. 1139-1148
    • Fried, L.E.1    Arbiser, J.L.2
  • 9
    • 84928162648 scopus 로고    scopus 로고
    • Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
    • [9] Pillai, V.B., et al. Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3. Nat. Commun., 6, 2015.
    • (2015) Nat. Commun. , vol.6
    • Pillai, V.B.1
  • 10
    • 0032977989 scopus 로고    scopus 로고
    • Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam‐like side‐effects in mice
    • [10] Kuribara, H., Stavinoha, W.B., Maruyama, Y., Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam‐like side‐effects in mice. J. Pharm. Pharmacol. 51:1 (1999), 97–103.
    • (1999) J. Pharm. Pharmacol. , vol.51 , Issue.1 , pp. 97-103
    • Kuribara, H.1    Stavinoha, W.B.2    Maruyama, Y.3
  • 11
    • 84893855866 scopus 로고    scopus 로고
    • Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes
    • [11] Chen, Y.J., et al. Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes. J. Orthop. Res. 32:4 (2014), 573–580.
    • (2014) J. Orthop. Res. , vol.32 , Issue.4 , pp. 573-580
    • Chen, Y.J.1
  • 12
    • 84956959206 scopus 로고    scopus 로고
    • Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats
    • [12] Yu, Y., et al. Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats. Mol. Med. Rep. 13:2 (2016), 1353–1360.
    • (2016) Mol. Med. Rep. , vol.13 , Issue.2 , pp. 1353-1360
    • Yu, Y.1
  • 13
    • 84870161284 scopus 로고    scopus 로고
    • Honokiol: a novel natural agent for cancer prevention and therapy
    • [13] Arora, S.et al., Honokiol: a novel natural agent for cancer prevention and therapy. Curr. Mol. Med., 12(10), 2012, 1244.
    • (2012) Curr. Mol. Med. , vol.12 , Issue.10 , pp. 1244
    • Arora, S.E.A.1
  • 14
    • 48749104995 scopus 로고    scopus 로고
    • Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer
    • [14] Liu, H., et al. Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer. Eur. J. Pharmacol. 591:1 (2008), 43–51.
    • (2008) Eur. J. Pharmacol. , vol.591 , Issue.1 , pp. 43-51
    • Liu, H.1
  • 15
    • 9244244137 scopus 로고    scopus 로고
    • Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
    • [15] Chen, F., et al. Honokiol: a potent chemotherapy candidate for human colorectal carcinoma. World J. Gastroenterol.: WJG 10:23 (2004), 3459–3463.
    • (2004) World J. Gastroenterol.: WJG , vol.10 , Issue.23 , pp. 3459-3463
    • Chen, F.1
  • 16
    • 84866524759 scopus 로고    scopus 로고
    • Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules
    • [16] Jeong, J.J., et al. Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules. Int. J. Oncol. 41:4 (2012), 1358–1364.
    • (2012) Int. J. Oncol. , vol.41 , Issue.4 , pp. 1358-1364
    • Jeong, J.J.1
  • 17
    • 22144452194 scopus 로고    scopus 로고
    • The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells
    • [17] Battle, T.E., Arbiser, J., Frank, D.A., The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells. Blood 106:2 (2005), 690–697.
    • (2005) Blood , vol.106 , Issue.2 , pp. 690-697
    • Battle, T.E.1    Arbiser, J.2    Frank, D.A.3
  • 18
    • 35848945708 scopus 로고    scopus 로고
    • Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity
    • [18] Hahm, E.-R., Singh, S.V., Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity. Mol. Cancer Ther. 6:10 (2007), 2686–2695.
    • (2007) Mol. Cancer Ther. , vol.6 , Issue.10 , pp. 2686-2695
    • Hahm, E.-R.1    Singh, S.V.2
  • 19
    • 0036569921 scopus 로고    scopus 로고
    • Down-modulation of Bcl-X L, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells
    • [19] Yang, S.-E., et al. Down-modulation of Bcl-X L, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells. Biochem. Pharmacol. 63:9 (2002), 1641–1651.
    • (2002) Biochem. Pharmacol. , vol.63 , Issue.9 , pp. 1641-1651
    • Yang, S.-E.1
  • 20
    • 49649114129 scopus 로고    scopus 로고
    • Honokiol: a natural therapeutic candidate, induces apoptosis and inhibits angiogenesis of ovarian tumor cells
    • [20] Li, Z., et al. Honokiol: a natural therapeutic candidate, induces apoptosis and inhibits angiogenesis of ovarian tumor cells. Eur. J. Obstet. Gynecol. Reprod. Biol. 140:1 (2008), 95–102.
    • (2008) Eur. J. Obstet. Gynecol. Reprod. Biol. , vol.140 , Issue.1 , pp. 95-102
    • Li, Z.1
  • 21
    • 33749321904 scopus 로고    scopus 로고
    • Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-κB activation pathway
    • [21] Ahn, K.S., et al. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-κB activation pathway. Mol. Cancer Res. 4:9 (2006), 621–633.
    • (2006) Mol. Cancer Res. , vol.4 , Issue.9 , pp. 621-633
    • Ahn, K.S.1
  • 22
    • 61849134849 scopus 로고    scopus 로고
    • Liposomal honokiol: a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity
    • [22] Hu, J., et al. Liposomal honokiol: a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity. Exp. Mol. Med. 40:6 (2008), 617–628.
    • (2008) Exp. Mol. Med. , vol.40 , Issue.6 , pp. 617-628
    • Hu, J.1
  • 23
    • 77949634480 scopus 로고    scopus 로고
    • A novel transdermal honokiol formulation based on Pluronic F127 copolymer
    • [23] Zheng, X., et al. A novel transdermal honokiol formulation based on Pluronic F127 copolymer. Drug Deliv. 17:3 (2010), 138–144.
    • (2010) Drug Deliv. , vol.17 , Issue.3 , pp. 138-144
    • Zheng, X.1
  • 24
    • 84954372708 scopus 로고    scopus 로고
    • Piperlongumine for enhancing oral bioavailability and cytotoxicity of docetaxel in triple-negative Breast cancer
    • [24] Patel, K., et al. Piperlongumine for enhancing oral bioavailability and cytotoxicity of docetaxel in triple-negative Breast cancer. J. Pharm. Sci. 104:12 (2015), 4417–4426.
    • (2015) J. Pharm. Sci. , vol.104 , Issue.12 , pp. 4417-4426
    • Patel, K.1
  • 25
    • 84952876656 scopus 로고    scopus 로고
    • Novel gefitinib formulation with improved oral bioavailability in treatment of A431 skin carcinoma
    • [25] Godugu, C., et al. Novel gefitinib formulation with improved oral bioavailability in treatment of A431 skin carcinoma. Pharm. Res. 33:1 (2016), 137–154.
    • (2016) Pharm. Res. , vol.33 , Issue.1 , pp. 137-154
    • Godugu, C.1
  • 26
    • 84988019856 scopus 로고    scopus 로고
    • Novel Diindolylmethane derivatives based NLC formulations to improve the oral Bioavailability and anticancer effects in Triple Negative Breast Cancer
    • [26] Godugu, C., et al. Novel Diindolylmethane derivatives based NLC formulations to improve the oral Bioavailability and anticancer effects in Triple Negative Breast Cancer. Eur. J. Pharm. Biopharm., 2016.
    • (2016) Eur. J. Pharm. Biopharm.
    • Godugu, C.1
  • 27
    • 79953026443 scopus 로고    scopus 로고
    • Formulation of docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycolsuccinate 2000 (Vitamin E TPGS 2k) micelles for targeted and synergistic chemotherapy
    • [27] Mi, Y., Liu, Y., Feng, S.-S., Formulation of docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycolsuccinate 2000 (Vitamin E TPGS 2k) micelles for targeted and synergistic chemotherapy. Biomaterials 32:16 (2011), 4058–4066.
    • (2011) Biomaterials , vol.32 , Issue.16 , pp. 4058-4066
    • Mi, Y.1    Liu, Y.2    Feng, S.-S.3
  • 28
    • 0028212240 scopus 로고
    • Pharmacokinetics of honokiol after intravenous administration in rats assessed using high performance liquid chromatography
    • [28] Tsai, T.-H., et al. Pharmacokinetics of honokiol after intravenous administration in rats assessed using high performance liquid chromatography. J. Chromatogr. B: Biomed. Sci. Appl. 655:1 (1994), 41–45.
    • (1994) J. Chromatogr. B: Biomed. Sci. Appl. , vol.655 , Issue.1 , pp. 41-45
    • Tsai, T.-H.1
  • 29
    • 84990829897 scopus 로고    scopus 로고
    • Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs
    • [29] Reddy, D.R.et al., Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs. SpringerPlus, 5(1), 2016, 1618.
    • (2016) SpringerPlus , vol.5 , Issue.1 , pp. 1618
    • Reddy, D.R.E.A.1
  • 30
    • 84930674490 scopus 로고    scopus 로고
    • Evaluation of spray BIO-Max DIM-P in dogs for oral bioavailability and in nu/nu mice bearing orthotopic/metastatic lung tumor models for anticancer activity
    • [30] Patel, A.R., et al. Evaluation of spray BIO-Max DIM-P in dogs for oral bioavailability and in nu/nu mice bearing orthotopic/metastatic lung tumor models for anticancer activity. Pharm. Res. 32:7 (2015), 2292–2300.
    • (2015) Pharm. Res. , vol.32 , Issue.7 , pp. 2292-2300
    • Patel, A.R.1
  • 31
    • 84884306434 scopus 로고    scopus 로고
    • Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models
    • [31] Godugu, C., et al. Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models. J. Controll. Release 172:1 (2013), 86–95.
    • (2013) J. Controll. Release , vol.172 , Issue.1 , pp. 86-95
    • Godugu, C.1
  • 32
    • 84908461327 scopus 로고    scopus 로고
    • Selenium nanoparticles involve HSP-70 and SIRT1 in preventing the progression of type 1 diabetic nephropathy
    • [32] Kumar, G.S., et al. Selenium nanoparticles involve HSP-70 and SIRT1 in preventing the progression of type 1 diabetic nephropathy. Chem. Biol. Interactions 223 (2014), 125–133.
    • (2014) Chem. Biol. Interactions , vol.223 , pp. 125-133
    • Kumar, G.S.1
  • 33
    • 85026618432 scopus 로고    scopus 로고
    • Triple-negative breast cancer—current status and future directions
    • [33] Gluz, O., et al. Triple-negative breast cancer—current status and future directions. Ann. Oncol., 2009, 2016, pmdp492.
    • (2016) Ann. Oncol. , vol.2009 , pp. pmdp492
    • Gluz, O.1
  • 34
    • 74249107837 scopus 로고    scopus 로고
    • Preparation of MPEG–PLA nanoparticle for honokiol delivery in vitro
    • [34] Zheng, X., et al. Preparation of MPEG–PLA nanoparticle for honokiol delivery in vitro. Int. J. Pharm. 386:1 (2010), 262–267.
    • (2010) Int. J. Pharm. , vol.386 , Issue.1 , pp. 262-267
    • Zheng, X.1
  • 35
    • 84892653904 scopus 로고    scopus 로고
    • Honokiol nanosuspensions: preparation, increased oral bioavailability and dramatically enhanced biodistribution in the cardio-cerebro-vascular system
    • [35] Han, M., et al. Honokiol nanosuspensions: preparation, increased oral bioavailability and dramatically enhanced biodistribution in the cardio-cerebro-vascular system. Colloids Surf. B: Biointerfaces 116 (2014), 114–120.
    • (2014) Colloids Surf. B: Biointerfaces , vol.116 , pp. 114-120
    • Han, M.1
  • 36
    • 84954531986 scopus 로고    scopus 로고
    • Sirolimus-loaded polymeric micelles with honokiol for oral delivery
    • [36] Li, X., et al. Sirolimus-loaded polymeric micelles with honokiol for oral delivery. J. Pharm. Pharmacol. 67:12 (2015), 1663–1672.
    • (2015) J. Pharm. Pharmacol. , vol.67 , Issue.12 , pp. 1663-1672
    • Li, X.1
  • 37
    • 85006267376 scopus 로고    scopus 로고
    • Co-delivery of honokiol, a constituent of Magnolia species, in a self-microemulsifying drug delivery system for improved oral transport of lipophilic sirolimus
    • [37] Ding, W., et al. Co-delivery of honokiol, a constituent of Magnolia species, in a self-microemulsifying drug delivery system for improved oral transport of lipophilic sirolimus. Drug Deliv. 2015 (2016), 1–11.
    • (2016) Drug Deliv. , vol.2015 , pp. 1-11
    • Ding, W.1
  • 38
    • 77951835943 scopus 로고    scopus 로고
    • Biodegradable self-assembled PEG–PCL–PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization
    • [38] Gong, C., et al. Biodegradable self-assembled PEG–PCL–PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization. Nanotechnology, 21(21), 2010, 215103.
    • (2010) Nanotechnology , vol.21 , Issue.21 , pp. 215103
    • Gong, C.1
  • 39
    • 84937434471 scopus 로고    scopus 로고
    • Encapsulation of honokiol into self-assembled pectin nanoparticles for drug delivery to HepG2 cells
    • [39] Zhang, Y., et al. Encapsulation of honokiol into self-assembled pectin nanoparticles for drug delivery to HepG2 cells. Carbohydr. Polym. 133 (2015), 31–38.
    • (2015) Carbohydr. Polym. , vol.133 , pp. 31-38
    • Zhang, Y.1
  • 40
    • 84872029247 scopus 로고    scopus 로고
    • Inhibition of class I histone deacetylases in non-small cell lung cancer by honokiol leads to suppression of cancer cell growth and induction of cell death in vitro and in vivo
    • [40] Singh, T., Prasad, R., Katiyar, S.K., Inhibition of class I histone deacetylases in non-small cell lung cancer by honokiol leads to suppression of cancer cell growth and induction of cell death in vitro and in vivo. Epigenetics 8:1 (2013), 54–65.
    • (2013) Epigenetics , vol.8 , Issue.1 , pp. 54-65
    • Singh, T.1    Prasad, R.2    Katiyar, S.K.3
  • 41
    • 84863469971 scopus 로고    scopus 로고
    • Improvement of oral bioavailability of glycyrrhizin by sodium deoxycholate/phospholipid-mixed nanomicelles
    • [41] Jin, S., et al. Improvement of oral bioavailability of glycyrrhizin by sodium deoxycholate/phospholipid-mixed nanomicelles. J. Drug Target. 20:7 (2012), 615–622.
    • (2012) J. Drug Target. , vol.20 , Issue.7 , pp. 615-622
    • Jin, S.1
  • 42
    • 84974593817 scopus 로고    scopus 로고
    • Quercetin-loaded freeze-dried nanomicelles: improving absorption and anti-glioma efficiency in vitro and in vivo
    • [42] Wang, G., et al. Quercetin-loaded freeze-dried nanomicelles: improving absorption and anti-glioma efficiency in vitro and in vivo. J. Controll. Release, 2016.
    • (2016) J. Controll. Release
    • Wang, G.1
  • 43
    • 57749176217 scopus 로고    scopus 로고
    • A potential therapeutic strategy for diabetes and its complications in the form of co-encapsulated antioxidant nanoparticles (NanoCAPs) of ellagic acid and coenzyme Q10: preparation and evaluation in streptozotocin induced diabetic rats
    • [43] Ratnam, D.V., et al. A potential therapeutic strategy for diabetes and its complications in the form of co-encapsulated antioxidant nanoparticles (NanoCAPs) of ellagic acid and coenzyme Q10: preparation and evaluation in streptozotocin induced diabetic rats. J. Biomed. Nanotechnol. 4:1 (2008), 33–43.
    • (2008) J. Biomed. Nanotechnol. , vol.4 , Issue.1 , pp. 33-43
    • Ratnam, D.V.1
  • 44
    • 79961070767 scopus 로고    scopus 로고
    • Augmented anticancer efficacy of doxorubicin-loaded polymeric nanoparticles after oral administration in a breast cancer induced animal model
    • [44] Jain, A.K., et al. Augmented anticancer efficacy of doxorubicin-loaded polymeric nanoparticles after oral administration in a breast cancer induced animal model. Mol. Pharm. 8:4 (2011), 1140–1151.
    • (2011) Mol. Pharm. , vol.8 , Issue.4 , pp. 1140-1151
    • Jain, A.K.1
  • 45
    • 84976504728 scopus 로고    scopus 로고
    • Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer
    • [45] Doddapaneni, R., Patel, K., Chowdhury, N., Singh, M., Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer. Exp. Cell Res. 346:1 (2016), 65–73.
    • (2016) Exp. Cell Res. , vol.346 , Issue.1 , pp. 65-73
    • Doddapaneni, R.1    Patel, K.2    Chowdhury, N.3    Singh, M.4
  • 46
    • 84951279788 scopus 로고    scopus 로고
    • Tumor neovasculature-targeted cationic PEGylated liposomes of gambogic acid for the treatment of triple-negative breast cancer
    • [46] Doddapaneni, R., Patel, K., Owaid, I.H., Singh, M., Tumor neovasculature-targeted cationic PEGylated liposomes of gambogic acid for the treatment of triple-negative breast cancer. Drug Deliv. 23:4 (2016), 1232–1241.
    • (2016) Drug Deliv. , vol.23 , Issue.4 , pp. 1232-1241
    • Doddapaneni, R.1    Patel, K.2    Owaid, I.H.3    Singh, M.4
  • 47
    • 84971384509 scopus 로고    scopus 로고
    • Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer
    • [47] Patel, K., Doddapaneni, R., Chowdhury, N., Boakye, C.H., Behl, G., Singh, M., Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer. Nanomedicine (Lond). 11:11 (2016), 1377–1392.
    • (2016) Nanomedicine (Lond). , vol.11 , Issue.11 , pp. 1377-1392
    • Patel, K.1    Doddapaneni, R.2    Chowdhury, N.3    Boakye, C.H.4    Behl, G.5    Singh, M.6
  • 48
    • 84935421903 scopus 로고    scopus 로고
    • Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity
    • [48] Patel, A.R., Doddapaneni, R., Andey, T., Wilson, H., Safe, S., Singh, M., Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity. J. Control Release 10:213 (2015), 18–26.
    • (2015) J. Control Release , vol.10 , Issue.213 , pp. 18-26
    • Patel, A.R.1    Doddapaneni, R.2    Andey, T.3    Wilson, H.4    Safe, S.5    Singh, M.6
  • 49
    • 84973622067 scopus 로고    scopus 로고
    • Combination Approach of YSA Peptide Anchored Docetaxel Stealth Liposomes with Oral Antifibrotic Agent for the Treatment of Lung Cancer
    • [49] Patel, K., Doddapaneni, R., Sekar, V., Chowdhury, N., Singh, M., Combination Approach of YSA Peptide Anchored Docetaxel Stealth Liposomes with Oral Antifibrotic Agent for the Treatment of Lung Cancer. Mol. Pharm. 6 (2016), 2049–2058.
    • (2016) Mol. Pharm. , vol.6 , pp. 2049-2058
    • Patel, K.1    Doddapaneni, R.2    Sekar, V.3    Chowdhury, N.4    Singh, M.5
  • 50
    • 84881326733 scopus 로고    scopus 로고
    • Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)[HYPHEN]1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1)
    • [50] Boakye, C.H., Doddapaneni, R., Shah, P.P., Patel, A.R., Godugu, C., Safe, S., Katiyar, S.K., Singh, M., Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)[HYPHEN]1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1). PLoS One, 8, 2013, e69519.
    • (2013) PLoS One , vol.8 , pp. e69519
    • Boakye, C.H.1    Doddapaneni, R.2    Shah, P.P.3    Patel, A.R.4    Godugu, C.5    Safe, S.6    Katiyar, S.K.7    Singh, M.8
  • 51
    • 79959648566 scopus 로고    scopus 로고
    • Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells
    • [51] Arora, S.et al., Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells. PLoS One, 6(6), 2011, e21573.
    • (2011) PLoS One , vol.6 , Issue.6 , pp. e21573
    • Arora, S.E.A.1
  • 52
    • 9244244137 scopus 로고    scopus 로고
    • Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
    • [52] Chen, F., et al. Honokiol: a potent chemotherapy candidate for human colorectal carcinoma. World J. Gastroenterol. 10:23 (2004), 3459–3463.
    • (2004) World J. Gastroenterol. , vol.10 , Issue.23 , pp. 3459-3463
    • Chen, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.