Augmented anticancer efficacy of doxorubicin-loaded polymeric nanoparticles after oral administration in a breast cancer induced animal model

Molecular Pharmaceutics

Volumn 8, Issue 4, 2011, Pages 1140-1151

  Jain, Amit K ^a   Swarnakar, Nitin K ^a   Das, Manasmita ^a   Godugu, Chandraiah ^a   Singh, Raman Preet ^a   Rao, Poduri Rama ^a,b   Jain, Sanyog ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b CENTRAL UNIVERSITY OF PUNJAB   (India)

Author keywords

doxorubicin; nuclear localization; oral delivery; PLGA nanoparticles

Indexed keywords

CREATINE KINASE; DOXORUBICIN; GLUTATHIONE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NANOPARTICLE; POLY(LACTIC CO GLYCOLIC ACID); POLYGLYCOLIC ACID; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CARDIOTOXICITY; CONFOCAL LASER MICROSCOPY; CYTOTOXICITY; DRUG EFFICACY; DRUG UPTAKE; FEMALE; IC 50; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CACO-2 CELLS; CELL LINE, TUMOR; CREATINE KINASE; DOXORUBICIN; FEMALE; GLUTATHIONE; HUMANS; KAPLAN-MEIER ESTIMATE; L-LACTATE DEHYDROGENASE; LACTIC ACID; MALONDIALDEHYDE; MICE; MICROSCOPY, ATOMIC FORCE; NANOPARTICLES; POLYGLYCOLIC ACID; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE;

EID: 79961070767     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200011f     Document Type: Article

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