Quercetin-loaded freeze-dried nanomicelles: Improving absorption and anti-glioma efficiency in vitro and in vivo

Journal of Controlled Release

Volumn 235, Issue , 2016, Pages 276-290

  Wang, Gang ^a   Wang, Jun Jie ^a,b   Chen, Xuan Li ^b   Du, Li ^a   Li, Fei ^a  

^a JIANGSU UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

Author keywords

BBB; Freeze dried; Glioma; Nanomicelles; Quercetin

Indexed keywords

CHEMOTHERAPY; DRUG PRODUCTS; EFFICIENCY; FINITE DIFFERENCE METHOD; FLAVONOIDS; LOW TEMPERATURE DRYING; MICELLES; PARTICLE SIZE; PHENOLS;

AQUEOUS SOLUBILITY; BLOOD-BRAIN BARRIER; CHEMOPREVENTIVE AGENTS; GLIOMA; INTRACELLULAR UPTAKE; NANOMICELLES; QUERCETIN; VACUUM-FREEZE DRYING;

TUMORS;

LACTATE DEHYDROGENASE; NANOMATERIAL; NANOMICELLE; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; QUERCETIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CANCER CELL CULTURE; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG TRANSPORT; EVAPORATION; FREEZE DRYING; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; LIVER; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPLEEN; ZETA POTENTIAL; ADMINISTRATION AND DOSAGE; ANIMAL; BAGG ALBINO MOUSE; BRAIN TUMOR; CELL SURVIVAL; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG EFFECTS; HUMAN; INTESTINE ABSORPTION; METABOLISM; MICELLE; NUDE MOUSE; PATHOLOGY; PHARMACOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; FREEZE DRYING; GLIOMA; HUMANS; INTESTINAL ABSORPTION; MICE, INBRED BALB C; MICE, NUDE; MICELLES; NANOPARTICLES; QUERCETIN; TUMOR BURDEN;

EID: 84974593817     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.05.045     Document Type: Article

References (52)

1. S.L. Hervey-Jumper, J. Li, D. Lau, A.M. Molinaro, D.W. Perry, L. Meng, and M.S. Berger Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period J. Neurosurg. 123 2 2015 325 339
2. M.G. Castro, R. Cowen, I.K. Williamson, A. David, M.J. Jimenez-Dalmaroni, X. Yuan, A. Bigliari, J.C. Williams, J. Hu, and P.R. Lowenstein Current and future strategies for the treatment of malignant brain tumors Pharmacol. Ther. 98 2003 71 108
3. B. Mishra, B.B. Patel, and S. Tiwari Colloidal nanocarriers: a review on formulation technology, types and applications toward targeted drug delivery Nanosci. Nanotechnol. 6 2010 9 24
4. C.P. Xavier, C.F. Lima, M. Rohde, and C. Pereira-Wilson Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation Cancer Chemother. Pharmacol. 68 2011 1449 1457
5. M.D. Siegelin, D.E. Reuss, A. Habel, A. Rami, and A. von Deimling Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells Neuro-Oncology 11 2009 122 131
6. E. Lugli, R. Ferraresi, E. Roat, L. Troiano, M. Pinti, and M. Nasi Quercetin inhibits lymphocyte activation and proliferation without inducing apoptosis in peripheral mononuclear cells Leuk. Res. 33 2009 140 150
7. E.C. Lavellea, S. Sharif, N.W. Thomas, J. Holland, and S.S. Davis The importance of gastrointestinal uptake of particles in the design of oral delivery systems Adv. Drug Deliv. Rev. 18 1995 5 22
8. G. Wang, J.J. Wang, G.Y. Yang, S.M. Du, N. Zeng, D.S. Li, R.M. Li, J.Y. Chen, J.B. Feng, S.H. Yuan, and F. Ye Effects of quercetin nanoliposomes on C6 glioma cells through induction of type III programmed cell death Int. J. Nanomedicine 7 2012 271 280
9. T. Vasconcelos, B. Sarmento, and P. Costa Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs Drug Discov. Today 12 2007 1068 1075
10. R.M. Heilmann, A. Grellet, K. Allenspach, P. Lecoindre, M.J. Day, S.L. Priestnall, L. Toresson, F. Procoli, N. Grützner, J.S. Suchodolski, and J.M. Steiner Association between fecal S100A12 concentration and histologic, endoscopic, and clinical disease severity in dogs with idiopathic inflammatory bowel disease Vet. Immunol. Immunopathol. 158 3-4 2014 156 166
11. L.H. Dian, Z.W. Yang, F. Li, Z.H. Wang, X. Pan, X.S. Peng, X.T. Huang, Z.F. Guo, G.L. Quan, X. Shi, B. Chen, G. Li, and C.B. Wu Cubic phase nanoparticles for sustained release of ibuprofen: formulation, characterization and enhanced bioavailability study Int. J. Nanomedicine 8 2013 845 854
12. A.P.R. Johnston, G.K. Such, S.L. Ng, and F. Caruso Challenges facing colloidal delivery systems: FROM synthesis to the clinic Curr. Opin. Colloid Interface Sci. 16 2011 171 181
13. H.M. Aliabadi, M. Shahin, D.R. Brocks, and A. Lavasanifar Disposition of drugs in block copolymer micelle delivery systems: from discovery to recovery Clin. Pharmacokinet. 47 2008 619 634
14. U. Katragadda, Q. Teng, B.M. Rayaprolu, T. Chandran, and C. Tan Multi-drug delivery to tumor cells via micellar nanocarriers Int. J. Pharm. 419 2011 281 286
15. M. Licciardi, G. Cavallaro, M. Di Stefano, G. Pitarresi, C. Fiorica, and G. Giammona New self-assembling polyaspartylhydrazide copolymer micelles for anticancer drug delivery Int. J. Pharm. 396 2010 219 228
16. K.H. Min, J.H. Kim, S.M. Bae, H. Shin, M.S. Kim, S. Park, H. Lee, R.W. Park, I.S. Kim, K. Kim, I.C. Kwon, S.Y. Jeong, and D.S. Lee Tumoral acidic pH- responsive MPEG-poly(beta-amino ester) polymeric micelles for cancer targeting therapy J. Control. Release 144 2010 259 266
17. M. Li, A. Chrastina, T. Levchenko, and V.P. Torchilin Micelles from poly(ethylene glycol)-phosphatidyl ethanolamine conjugates (PEG-PE) as pharmaceutical nanocarriers for poorly soluble drug camptothecin J. Biomed. Nanotechnol. 1 2005 190 195
18. J. Beirowski, S. Inghelbrecht, A. Arien, and H. Gieseler Freeze-drying of nanosuspensions, part 3: investigation of factors compromising storage stability of highly concentrated drug nanosuspensions J. Pharm. Sci. 101 2012 354 362
19. H. Yuan, J. Chen, Y.Z. Du, F.Q. Hu, S. Zeng, and H.L. Zhao Studies on oral absorption of stearic acid SLN by a novel fuorometric method Colloids Surf. B: Biointerfaces 58 2007 157 164
20. H.L. Wong, R. Bendayan, A.M. Rauth, Y. Li, and X.Y. Wu Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles Adv. Drug Deliv. Rev. 59 2007 491 504
21. Q. Lv, X. Li, B. Shen, H. Xu, C. Shen, L. Dai, J. Bai, H. Yuan, and J. Han Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration Int. J. Nanomedicine 9 2014 505 515
22. S. Eaimtrakarn, Y.V. Rama Prasad, and T. Ohno Absorption enhancing effect of Labrasol on the intestinal absorption of insulin in rats J. Drug Target. 10 3 2002 255 260
23. K. Koga, Y. Kusawake, Y. Ito, N. Sugioka, N. Shibata, and K. Takada Enhancing mechanism of Labrasol on intestinal membrane permeability of the hydrophilic drug gentamicin sulfate Eur. J. Pharm. Biopharm. 64 1 2006 82 91
24. X. Zhang, J.K. Jackson, and M.H. Burt Determination of surfactant critical micelle concentration by a novel fluorescence depolarization technique J. Biochem. Biophys. Methods 31 3-4 1996 145 150
25. R. Ghaffarian, T. Bhowmick, and S. Muro Transport of nanocarriers across gastrointestinal epithelial cells by a new transcellular route induced by targeting ICAM-1 J. Control. Release 163 1 2012 25 33
26. P.J. Gaillard, H.V. Voorwinden, J.L. Nielsen, A. Ivanov, R. Atsumi, H. Engman, C. Rinbom, A.G. De Boer, and D.D. Breimer Establishment and functional characterization of an in vitro model of the blood-brain barrier comprising a co-culture of brain capillary endothelial cells and astrocytes Eur. J. Pharm. Sci. 12 2001 215 222
27. Y. Xie, L. Ye, X. Zhang, W. Cui, J. Lou, T. Nagai, and X. Hou Transport of nerve growth factor encapsulated into liposomes across the blood-brain barrier: in vitro and in vivo studies J. Control. Release 105 1-2 2005 106 119
28. F. Bian, L. Jia, W. Yu, and M. Liu Self-assembled micelles of N-phthaloylchitosan-g-polyvinyl-pyrrolidone for drug delivery Carbohydr. Polym. 76 3 2009 454 459
29. J. Varshosaz, S. Ghaffari, M.R. Khoshayand, F. Atyabi, A.J. Dehkordi, and F. Kobarfard Optimization of freeze-drying condition of amikacin solid lipid nanoparticles using D-optimal experimental design Pharm. Dev. Technol. 17 2012 187 194
30. R.Z. Xiao, Z.W. Zeng, G.L. Zhou, J.J. Wang, F.Z. Li, and A.M. Wang Recent advances in PEG-PLA block copolymer nanoparticles Int. J. Nanomedicine 5 2010 1057 1065
31. K.K. Gill, A. Kaddoumi, and S. Nazzal PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication J. Drug Target. 30 2014 1 10
32. J. Varshosaz, S. Taymouri, F. Hassanzadeh, S.H. Javanmard, and M. Rostami Self-assembly micelles with lipid core of cholesterol for docetaxel delivery to B16F10 melanoma and HepG2 cells J. Liposome Res. 2 2014 1 9
33. H. Xin, X. Sha, X. Jiang, L. Chen, K. Law, J. Gu, Y. Chen, X. Wang, and X. Fang The brain targeting mechanism of angiopep-conjugated poly(ethylene glycol)-co-poly(epsilon-caprolactone) nanoparticles Biomaterials 33 2012 1673 1681
34. G. Wang, J.J. Wang, L.P. Zhang, S. Ming du, L.J. Ying, W. Lei, and Y. Fang Liposomal quercetin: evaluating drug delivery in vitro and biodistribution in vivo Expert Opin. Drug Deliv. 9 6 2012 599 613
35. H. Li, X. Zhao, Y. Ma, G. Zhai, L. Li, and H. Lou Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles J. Control. Release 133 2009 238 244
36. A. Ghosh, A.K. Mandal, S. Sarkar, S. Panda, and N. Das Nanoencapsulation of quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats Life Sci. 84 2009 75 80
37. F.T. Vicentini, T.R. Simi, J.O. Del Ciampo, N.O. Wolga, D.L. Pitol, M.M. Iyomasa, M.V. Bentley, and M.J. Fonseca Quercetin in w/o microemulsion: in vitro and in vivo skin penetration and efficacy against UVB-induced skin damages evaluated in vivo Eur. J. Pharm. Biopharm. 69 2008 948 957
38. H.C. Shin, A.W. Alani, D.A. Rao, N.C. Rockich, and G.S. Kwon Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs J. Control. Release 140 3 2009 294 300
39. C. Rupp, H. Steckel, and B.W. Müller Solubilization of poorly water-soluble drugs by mixed micelles based on hydrogenated phosphatidylcholine Int. J. Pharm. 395 1-2 2010 272 280
40. K. Maiti, K. Mukherjee, A. Gantait, H.N. Ahamed, B.P. Saha, and P.K. Mukherjee Enhanced therapeutic benefit of quercetin-phospholipid complex in carbon tetrachloride-induced acute liver injury in rats: a comparative study Iran. J. Pharmacol. Ther. 4 2 2005 84 90
41. P.F. Yue, H.L. Yuan, X.Y. Li, M. Yang, and W.F. Zhu Process optimization, characterization and evaluation in vivo of oxymatrine-phospholipid complex Int. J. Pharm. 387 1-2 2010 139 146
42. Y. Lin, Q. Shen, and H. Katsumi Effects of Labrasol and other pharmaceutical excipients on the intestinal transport and absorption of rhodamine123, a P-glycoprotein substrate, in rats Biol. Pharm. Bull. 30 7 2007 1301 1307
43. S. Ganta, H. Devalapally, A. Shahiwala, and M. Amiji A review of stimuli-responsive nanocarriers for drug and gene delivery J. Control. Release 126 3 2008 187 204
44. S. Mezzenga, and R. Ulrich Spray-dried oil powder with ultrahigh oil content Langmuir 26 2010 16658 16661
45. S. Chen, H. Shi, M. Zhao, L. Zhang, H. He, and X. Tang A lyophilized etoposide submicron emulsion with a high drug loading for intravenous injection: preparation, evaluation, and pharmacokinetics in rats Drug Dev. Ind. Pharm. 36 2010 1444 1453
46. N. Wang, T. Wang, W. Sun, and T. Li Preparation of submicron liposomes exhibiting efficient entrapment of drugs by freeze-drying water-in-oil emulsions Chem. Phys. Lipids 164 2011 151 157
47. R.R. Sawant, and V.P. Torchilin Multifunctionality of lipid-core micelles for drug delivery and tumour targeting Mol. Membr. Biol. 27 2010 232 246
48. K.L. Hu, J.W. Li, and Y.H. Shen Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations J. Control. Release 134 2009 55 61
49. A. BE Duneau, P. Saulnier, and J.P. Benoit Active targeting of brain tumors using nanocarriers Biomaterials 28 33 2007 4947 4967
50. Y. Chen, and L. Liu Modern methods for delivery of drugs across the blood-brain barrier Adv. Drug Deliv. Rev. 64 7 2012 640 665
51. P.S. Wang, and S. Low Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells J. Control. Release 5 1998 39 48
52. S.Q. Liu, N. Wiradharma, S.J. Gao, Y.W. Tong, and Y.Y. Yang Bio-functional micelles self-assembled from a folate-conjugated block copolymer for targeted intracellular delivery of anticancer drugs Biomaterials 28 2007 1423 1433