Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

Nature Communications

Volumn 6, Issue , 2015, Pages

  Pillai, Vinodkumar B ^a   Samant, Sadhana ^a   Sundaresan, Nagalingam R ^a   Raghuraman, Hariharasundaram ^a   Kim, Gene ^a   Bonner, Michael Y ^b   Arbiser, Jack L ^b   Walker, Douglas I ^c   Jones, Dean P ^c   Gius, David ^d   Gupta, Mahesh P ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Department of Dermatology Atlanta Veterans Administration Health Center   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; HONOKIOL; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL PROTEIN; MYOSIN HEAVY CHAIN BETA; OLIGOMYCIN SENSITIVITY CONFERRING PROTEIN; REACTIVE OXYGEN METABOLITE; SIRTUIN 3; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; BIPHENYL DERIVATIVE; CARDIOTONIC AGENT; CARRIER PROTEIN; ISOPRENALINE; LIGNAN; MEMBRANE PROTEIN; OLIGOMYCIN SENSITIVITY-CONFERRING PROTEIN; PHENYLEPHRINE; SIRT3 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

CARDIOLOGY; GENETIC DIFFERENTIATION; HETEROTROPHY; MITOCHONDRION; OXYGEN; PHENOL; RODENT; SUBSTRATE; TREE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; FEMALE; HEART FIBROBLAST; HEART MITOCHONDRION; HEART MUSCLE FIBROSIS; HEART MUSCLE NECROSIS; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; MALE; MOUSE; MYOFIBROBLAST; NEWBORN; NONHUMAN; OXYGEN CONSUMPTION; PROTEIN ACETYLATION; RAT; SYNTHESIS; WILD TYPE; ACETYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CARDIOMEGALY; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

MAGNOLIA; MUS;

ACETYLATION; ADENOSINE TRIPHOSPHATASES; ANIMALS; BIPHENYL COMPOUNDS; CARDIOMEGALY; CARDIOTONIC AGENTS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION REGULATION; ISOPROTERENOL; LIGNANS; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MYOCARDIUM; MYOCYTES, CARDIAC; MYOFIBROBLASTS; PHENYLEPHRINE; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SIRTUIN 3; SUPEROXIDE DISMUTASE;

EID: 84928162648     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7656     Document Type: Article

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