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Volumn 591, Issue 1-3, 2008, Pages 43-51

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer

Author keywords

Apoptosis; Honokiol; Lapatinib; Proliferation; Rapamycin

Indexed keywords

DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; ESTROGEN RECEPTOR; HONOKIOL; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; SMALL INTERFERING RNA; TAMOXIFEN;

EID: 48749104995     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.026     Document Type: Article
Times cited : (121)

References (30)
  • 1
    • 33749321904 scopus 로고    scopus 로고
    • Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway
    • Ahn K.S., Sethi G., Shishodia S., Sung B., Arbiser J.L., and Aggarwal B.B. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway. Mol. Cancer Res. 4 (2006) 621-633
    • (2006) Mol. Cancer Res. , vol.4 , pp. 621-633
    • Ahn, K.S.1    Sethi, G.2    Shishodia, S.3    Sung, B.4    Arbiser, J.L.5    Aggarwal, B.B.6
  • 2
    • 27844445642 scopus 로고    scopus 로고
    • Perturbations of the AKT signaling pathway in human cancer
    • Altomare D.A., and Testa J.R. Perturbations of the AKT signaling pathway in human cancer. Oncogene 24 (2005) 7455-7464
    • (2005) Oncogene , vol.24 , pp. 7455-7464
    • Altomare, D.A.1    Testa, J.R.2
  • 4
    • 22144452194 scopus 로고    scopus 로고
    • The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells
    • Battle T.E., Arbiser J., and Frank D.A. The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells. Blood 106 (2005) 690-697
    • (2005) Blood , vol.106 , pp. 690-697
    • Battle, T.E.1    Arbiser, J.2    Frank, D.A.3
  • 5
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou T.C., and Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 22 (1984) 27-55
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 6
    • 42549148850 scopus 로고    scopus 로고
    • MDA-MB-435: The questionable use of a melanoma cell line as a model for human breast cancer is going on
    • Christgen M., and Lehmann U. MDA-MB-435: The questionable use of a melanoma cell line as a model for human breast cancer is going on. Cancer Biol. Ther. 6 (2007) 1355-1357
    • (2007) Cancer Biol. Ther. , vol.6 , pp. 1355-1357
    • Christgen, M.1    Lehmann, U.2
  • 7
    • 0036633164 scopus 로고    scopus 로고
    • Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
    • Clark A.S., West K., Streicher S., and Dennis P.A. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol. Cancer Ther. 1 (2002) 707-717
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 707-717
    • Clark, A.S.1    West, K.2    Streicher, S.3    Dennis, P.A.4
  • 9
    • 4944240759 scopus 로고    scopus 로고
    • Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid
    • Fong W.F., Tse A.K., Poon K.H., and Wang C. Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid. Int. J. Biochem. Cell Biol. 37 (2005) 427-441
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 427-441
    • Fong, W.F.1    Tse, A.K.2    Poon, K.H.3    Wang, C.4
  • 11
    • 33747146789 scopus 로고    scopus 로고
    • Lapatinib: a novel EGFR/HER-2 tyrosine kinase inhibitor for cancer
    • Johnston S.R., and Leary A. Lapatinib: a novel EGFR/HER-2 tyrosine kinase inhibitor for cancer. Drugs Today (Barc.) 42 (2006) 441-453
    • (2006) Drugs Today (Barc.) , vol.42 , pp. 441-453
    • Johnston, S.R.1    Leary, A.2
  • 12
    • 33748967935 scopus 로고    scopus 로고
    • Honokiol causes the p21WAF1-mediated G(1)-phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells
    • Lee B., Kim C.H., and Moon S.K. Honokiol causes the p21WAF1-mediated G(1)-phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells. FEBS Lett. 580 (2006) 5177-5184
    • (2006) FEBS Lett. , vol.580 , pp. 5177-5184
    • Lee, B.1    Kim, C.H.2    Moon, S.K.3
  • 13
    • 0041881635 scopus 로고    scopus 로고
    • The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production
    • Liou K.T., Shen Y.C., Chen C.F., Tsao C.M., and Tsai S.K. The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production. Eur. J. Pharmacol. 475 (2003) 19-27
    • (2003) Eur. J. Pharmacol. , vol.475 , pp. 19-27
    • Liou, K.T.1    Shen, Y.C.2    Chen, C.F.3    Tsao, C.M.4    Tsai, S.K.5
  • 14
    • 33646430295 scopus 로고    scopus 로고
    • Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18
    • Liu H., Zang C., Fenner M.H., Liu D., Possinger K., Koeffler H.P., and Elstner E. Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18. Blood 107 (2006) 3683-3692
    • (2006) Blood , vol.107 , pp. 3683-3692
    • Liu, H.1    Zang, C.2    Fenner, M.H.3    Liu, D.4    Possinger, K.5    Koeffler, H.P.6    Elstner, E.7
  • 15
    • 0028289204 scopus 로고
    • Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation
    • Lo Y.C., Teng C.M., Chen C.F., Chen C.C., and Hong C.Y. Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation. Biochem. Pharmacol. 47 (1994) 549-553
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 549-553
    • Lo, Y.C.1    Teng, C.M.2    Chen, C.F.3    Chen, C.C.4    Hong, C.Y.5
  • 17
    • 24044551995 scopus 로고    scopus 로고
    • PI3K/Akt/mTOR pathway as a target for cancer therapy
    • Morgensztern D., and McLeod H.L. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16 (2005) 797-803
    • (2005) Anticancer Drugs , vol.16 , pp. 797-803
    • Morgensztern, D.1    McLeod, H.L.2
  • 18
    • 0034764041 scopus 로고    scopus 로고
    • Inhibitory effect of magnolol and honokiol from Magnolia obovata on human fibrosarcoma HT-1080. Invasiveness in vitro
    • Nagase H., Ikeda K., and Sakai Y. Inhibitory effect of magnolol and honokiol from Magnolia obovata on human fibrosarcoma HT-1080. Invasiveness in vitro. Planta Med. 67 (2001) 705-708
    • (2001) Planta Med. , vol.67 , pp. 705-708
    • Nagase, H.1    Ikeda, K.2    Sakai, Y.3
  • 19
    • 31644439702 scopus 로고    scopus 로고
    • Herceptin: mechanisms of action and resistance
    • Nahta R., and Esteva F.J. Herceptin: mechanisms of action and resistance. Cancer Lett. 232 (2006) 123-138
    • (2006) Cancer Lett. , vol.232 , pp. 123-138
    • Nahta, R.1    Esteva, F.J.2
  • 20
    • 33646712747 scopus 로고    scopus 로고
    • Mechanisms of disease: understanding resistance to HER-2-targeted therapy in human breast cancer
    • Nahta R., Yu D., Hung M.C., Hortobagyi G.N., and Esteva F.J. Mechanisms of disease: understanding resistance to HER-2-targeted therapy in human breast cancer. Nat. Clin. Pract. Oncol. 3 (2006) 269-280
    • (2006) Nat. Clin. Pract. Oncol. , vol.3 , pp. 269-280
    • Nahta, R.1    Yu, D.2    Hung, M.C.3    Hortobagyi, G.N.4    Esteva, F.J.5
  • 22
    • 33644860893 scopus 로고    scopus 로고
    • Trastuzumab and antiestrogen therapy: focus on mechanisms of action and resistance
    • Ocana A., Cruz J.J., and Pandiella A. Trastuzumab and antiestrogen therapy: focus on mechanisms of action and resistance. Am. J. Clin. Oncol. 29 (2006) 90-95
    • (2006) Am. J. Clin. Oncol. , vol.29 , pp. 90-95
    • Ocana, A.1    Cruz, J.J.2    Pandiella, A.3
  • 23
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C.J. Cancer cell cycles. Science 274 (1996) 1672-1677
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 24
    • 26944444312 scopus 로고    scopus 로고
    • Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation
    • Tse A.K., Wan C.K., Shen X.L., Yang M., and Fong W.F. Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation. Biochem. Pharmacol. 70 (2005) 1443-1457
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 1443-1457
    • Tse, A.K.1    Wan, C.K.2    Shen, X.L.3    Yang, M.4    Fong, W.F.5
  • 25
    • 4344633662 scopus 로고    scopus 로고
    • Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO
    • Wang T., Chen F., Chen Z., Wu Y.F., Xu X.L., Zheng S., and Hu X. Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO. World J. Gastroenterol. 10 (2004) 2205-2208
    • (2004) World J. Gastroenterol. , vol.10 , pp. 2205-2208
    • Wang, T.1    Chen, F.2    Chen, Z.3    Wu, Y.F.4    Xu, X.L.5    Zheng, S.6    Hu, X.7
  • 26
    • 33749255173 scopus 로고    scopus 로고
    • Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol
    • Xu D., Lu Q., and Hu X. Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol. Cancer Lett. 243 (2006) 274-280
    • (2006) Cancer Lett. , vol.243 , pp. 274-280
    • Xu, D.1    Lu, Q.2    Hu, X.3
  • 27
    • 0036569921 scopus 로고    scopus 로고
    • Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells
    • Yang S.E., Hsieh M.T., Tsai T.H., and Hsu S.L. Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells. Biochem. Pharmacol. 63 (2002) 1641-1651
    • (2002) Biochem. Pharmacol. , vol.63 , pp. 1641-1651
    • Yang, S.E.1    Hsieh, M.T.2    Tsai, T.H.3    Hsu, S.L.4
  • 30
    • 33751422762 scopus 로고    scopus 로고
    • Honokiol up-regulates prostacyclin synthease protein expression and inhibits endothelial cell apoptosis
    • Zhang X., Chen S., and Wang Y. Honokiol up-regulates prostacyclin synthease protein expression and inhibits endothelial cell apoptosis. Eur. J. Pharmacol. 554 (2007) 1-7
    • (2007) Eur. J. Pharmacol. , vol.554 , pp. 1-7
    • Zhang, X.1    Chen, S.2    Wang, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.