Chemoprevention of Skin Cancer with 1,1-Bis (3′-Indolyl)-1-(Aromatic) Methane Analog through Induction of the Orphan Nuclear Receptor, NR4A2 (Nurr1)

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Boakye, Cedar H A ^a   Doddapaneni, Ravi ^a   Shah, Punit P ^a   Patel, Apurva R ^a   Godugu, Chandraiah ^a   Safe, Stephen ^b   Katiyar, Santosh K ^c   Singh, Mandip ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 BIS(3' INDOLYL) 1 (4 CHLOROPHENYL METHANE); 3,3' DIINDOLYLMETHANE; 3,3' DIINDOLYLMETHANE B; 3,3' DIINDOLYLMETHANE C; 8 HYDROXYDEOXYGUANOSINE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CASPASE 3; EPIGALLOCATECHIN GALLATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR RECEPTOR RELATED FACTOR 1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SKIN CANCER; ULTRAVIOLET B RADIATION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CATECHIN; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CHEMOPREVENTION; DEOXYGUANOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; INHIBITORY CONCENTRATION 50; KERATINOCYTES; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 84881326733     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069519     Document Type: Article

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