Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells

Biochemical Pharmacology

Volumn 63, Issue 9, 2002, Pages 1641-1651

  Yang, Shu Er ^a   Hsieh, Ming Tsuen ^a   Tsai, Tung Hu ^b   Hsu, Shih Lan ^c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Bad; Bcl XL; Caspase; Cytochrome c; Honokiol

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE 3; CASPASE INHIBITOR; CYTOCHROME C; HONOKIOL; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

APOPTOSIS; ARTICLE; CANCER CELL; CELL TYPE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-X PROTEIN; BIPHENYL COMPOUNDS; CASPASES; CYTOCHROME C GROUP; ENZYME ACTIVATION; HUMANS; LIGNANS; LUNG NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 0036569921     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00894-8     Document Type: Article

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