메뉴 건너뛰기




Volumn 18, Issue 2, 2013, Pages 123-133

Molecular characterization of basal-like and non-basal-like triple-negative breast cancer

Author keywords

Basal like; Breast cancer; Gene expression; Subtype; Triple negative

Indexed keywords

ALPHA6 INTEGRIN; ANDROGEN RECEPTOR; APOLIPOPROTEIN D; AURORA B KINASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIN B2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 4; KERATIN; MUCIN 1; PROGESTERONE RECEPTOR; PROTEIN P53; PROTEIN TYROSINE KINASE; UVOMORULIN;

EID: 84874376997     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2012-0397     Document Type: Article
Times cited : (443)

References (59)
  • 1
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumours. Nature 2000; 406:747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 2
    • 78951482208 scopus 로고    scopus 로고
    • Deconstructing the molecular portraits of breast cancer
    • Prat A, Perou CM. Deconstructing the molecular portraits of breast cancer. Mol Oncol 2011;5:5-23.
    • (2011) Mol Oncol , vol.5 , pp. 5-23
    • Prat, A.1    Perou, C.M.2
  • 3
    • 84655169981 scopus 로고    scopus 로고
    • Practical implications of gene-expression-based assays for breast oncologists
    • Prat A, Ellis MJ, Perou CM. Practical implications of gene-expression-based assays for breast oncologists. Nat Rev Clin Oncol 2012;9:48-57.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 48-57
    • Prat, A.1    Ellis, M.J.2    Perou, C.M.3
  • 4
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou C, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001;98:10869-10874.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.2    Tibshirani, R.3
  • 5
    • 78049453780 scopus 로고    scopus 로고
    • A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer
    • Nielsen TO, Parker JS, Leung S et al. A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer. Clin Cancer Res 2010;16:5222-5232.
    • (2010) Clin Cancer Res , vol.16 , pp. 5222-5232
    • Nielsen, T.O.1    Parker, J.S.2    Leung, S.3
  • 6
    • 44949228316 scopus 로고    scopus 로고
    • Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer
    • Martn M, Rodrguez-Lescure Á, Ruiz A, et al. Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer. J Natl Cancer Inst 2008; 100:805-814.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 805-814
    • Martn, M.1    Rodrguez-Lescure, Á.2    Ruiz, A.3
  • 7
    • 77951927588 scopus 로고    scopus 로고
    • A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada-Clinical Trials Group Trial, MA.12)
    • Bramwell VHC, Pritchard KI, Tu D, et al. A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada-Clinical Trials Group Trial, MA.12). Ann of Oncol. 2010;21:283-290.
    • (2010) Ann of Oncol , vol.21 , pp. 283-290
    • Bramwell, V.H.C.1    Pritchard, K.I.2    Tu, D.3
  • 8
    • 24644476579 scopus 로고    scopus 로고
    • Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: Update of National Cancer Institute of Canada Clinical Trials Group Trial MA5
    • Levine MN, Pritchard KI, Bramwell VHC, et al. Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: update of National Cancer Institute of Canada Clinical Trials Group Trial MA5. J Clin Oncol 2005;23:5166-5170.
    • (2005) J Clin Oncol , vol.23 , pp. 5166-5170
    • Levine, M.N.1    Pritchard, K.I.2    Bramwell, V.H.C.3
  • 9
    • 84872180537 scopus 로고    scopus 로고
    • Quantitative hormone receptors, triple-negative breast cancer (TNBC), and molecular subtypes: A collaborative effort of the BIG-NCI NABCG
    • Cheang M, Martin M, Nielsen T et al. Quantitative hormone receptors, triple-negative breast cancer (TNBC), and molecular subtypes: A collaborative effort of the BIG-NCI NABCG. Proc Am Soc Clin Oncol 2012;a1008.
    • (2012) Proc Am Soc Clin Oncol , pp. 1008
    • Cheang, M.1    Martin, M.2    Nielsen, T.3
  • 10
    • 78049308800 scopus 로고    scopus 로고
    • Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
    • Prat A, Parker J, Karginova O et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 2010;12:R68.
    • (2010) Breast Cancer Res , vol.12
    • Prat, A.1    Parker, J.2    Karginova, O.3
  • 11
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann BD, Bauer JA, Chen X et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2012;121:2750-2767.
    • (2012) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3
  • 12
    • 67649300721 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to the brain
    • Bos PD, Zhang XHF, Nadal C et al. Genes that mediate breast cancer metastasis to the brain. Nature 2009;459:1005-1009.
    • (2009) Nature , vol.459 , pp. 1005-1009
    • Bos, P.D.1    Zhang, X.H.F.2    Nadal, C.3
  • 13
    • 84859110592 scopus 로고    scopus 로고
    • Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse
    • Harrell J, Prat A, Parker J et al. Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse. Breast Cancer Res Treat 2012;132:523-535.
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 523-535
    • Harrell, J.1    Prat, A.2    Parker, J.3
  • 14
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profiles to predict distant metastasis of lymphnode-negative primary breast cancer
    • Wang Y, Klijn JG, Zhang Y et al. Gene-expression profiles to predict distant metastasis of lymphnode-negative primary breast cancer. Lancet 2005; 365:671-679.
    • (2005) Lancet , vol.365 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.2    Zhang, Y.3
  • 15
    • 79955798310 scopus 로고    scopus 로고
    • A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer
    • Hatzis C, Pusztai L, Valero V et al. A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. JAMA 2011;305:1873-1881.
    • (2011) JAMA , vol.305 , pp. 1873-1881
    • Hatzis, C.1    Pusztai, L.2    Valero, V.3
  • 16
    • 77954168391 scopus 로고    scopus 로고
    • Effect of training-sample size and classification difficulty on the accuracy of genomic predictors
    • Popovici V, Chen W, Gallas B et al. Effect of training-sample size and classification difficulty on the accuracy of genomic predictors. Breast Cancer Res 12:R5.
    • Breast Cancer Res , vol.12
    • Popovici, V.1    Chen, W.2    Gallas, B.3
  • 17
    • 78049466887 scopus 로고    scopus 로고
    • Evaluation of a 30-Gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer
    • Tabchy A, Valero V, Vidaurre T et al. Evaluation of a 30-Gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer. Clin Cancer Res 2010;16:5351-5361.
    • (2010) Clin Cancer Res , vol.16 , pp. 5351-5361
    • Tabchy, A.1    Valero, V.2    Vidaurre, T.3
  • 18
    • 79551710060 scopus 로고    scopus 로고
    • Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer
    • Iwamoto T, Bianchini G, Booser D et al. Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer. J Natl Cancer Inst 2011;103:264-272.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 264-272
    • Iwamoto, T.1    Bianchini, G.2    Booser, D.3
  • 19
    • 33749030177 scopus 로고    scopus 로고
    • Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer
    • Hess KR, Anderson K, Symmans WF et al. Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer. J Clin Oncol 2006;24:4236-4244.
    • (2006) J Clin Oncol , vol.24 , pp. 4236-4244
    • Hess, K.R.1    Anderson, K.2    Symmans, W.F.3
  • 20
    • 82455202257 scopus 로고    scopus 로고
    • DNA methylation profiling reveals a predominant immune component in breast cancers
    • Dedeurwaerder S, Desmedt C, Calonne E et al. DNA methylation profiling reveals a predominant immune component in breast cancers. EMBO Molecular Medicine 2011;3:726-741.
    • (2011) EMBO Molecular Medicine , vol.3 , pp. 726-741
    • Dedeurwaerder, S.1    Desmedt, C.2    Calonne, E.3
  • 21
    • 84874352046 scopus 로고    scopus 로고
    • International Genomics Consortium. expO offers free access to clinically annotated tumor data. Available at, Accessed January 18
    • International Genomics Consortium. expO offers free access to clinically annotated tumor data. Available at https://expo.intgen.org/geo/. Accessed January 18, 2013.
    • (2013)
  • 22
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, Gupta GP, Siegel PM et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518-524.
    • (2005) Nature , vol.436 , pp. 518-524
    • Minn, A.J.1    Gupta, G.P.2    Siegel, P.M.3
  • 23
    • 76349095348 scopus 로고    scopus 로고
    • Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer
    • Li Y, Zou L, Li Q et al. Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer. Nat Med 2010;16:214-218.
    • (2010) Nat Med , vol.16 , pp. 214-218
    • Li, Y.1    Zou, L.2    Li, Q.3
  • 24
    • 62449131093 scopus 로고    scopus 로고
    • Supervised risk predictor of breast cancer based on intrinsic subtypes
    • Parker JS, Mullins M, Cheang MCU et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 2009;27:1160-1167.
    • (2009) J Clin Oncol , vol.27 , pp. 1160-1167
    • Parker, J.S.1    Mullins, M.2    Cheang, M.C.U.3
  • 25
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumors
    • Network TCGA. Comprehensive molecular portraits of human breast tumors. Nature 2012; 490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
    • Network, T.C.G.A.1
  • 26
    • 77951139631 scopus 로고    scopus 로고
    • Genome remodelling in a basal-like breast cancer metastasis and xenograft
    • Ding L, Ellis MJ, Li S et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010;464:999-1005.
    • (2010) Nature , vol.464 , pp. 999-1005
    • Ding, L.1    Ellis, M.J.2    Li, S.3
  • 27
    • 0032441150 scopus 로고    scopus 로고
    • Cluster analysis and display of genome-wide expression patterns
    • Eisen MB, Spellman PT, Brown PO et al. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 1998;95:14863-14868.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14863-14868
    • Eisen, M.B.1    Spellman, P.T.2    Brown, P.O.3
  • 28
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for annotation, visualization, and Integrated discovery
    • Dennis G, Sherman BT, Hosack DA et al. DAVID: Database for annotation, visualization, and Integrated discovery. Genome Biol 2003;4:R60.
    • (2003) Genome Biol , vol.4
    • Dennis, G.1    Sherman, B.T.2    Hosack, D.A.3
  • 29
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001;98: 5116-5121.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 30
    • 79951962586 scopus 로고    scopus 로고
    • Breast carcinomas arising at a young age: Unique biology or a surrogate for aggressive intrinsic subtypes?
    • Anders CK, Fan C, Parker JS et al. Breast carcinomas arising at a young age: Unique biology or a surrogate for aggressive intrinsic subtypes? J Clin Oncol 2011;29:e18-e20.
    • (2011) J Clin Oncol , vol.29
    • Anders, C.K.1    Fan, C.2    Parker, J.S.3
  • 31
    • 78650675585 scopus 로고    scopus 로고
    • Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
    • Fedele CG, Ooms LM, Ho M et al. Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers. Proc Natl Acad Sci U S A 2010;107:22231-22236.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 22231-22236
    • Fedele, C.G.1    Ooms, L.M.2    Ho, M.3
  • 32
    • 67651148274 scopus 로고    scopus 로고
    • Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
    • Gewinner C, Wang ZC, Richardson A et al. Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Cancer Cell 2009;16:115-125.
    • (2009) Cancer Cell , vol.16 , pp. 115-125
    • Gewinner, C.1    Wang, Z.C.2    Richardson, A.3
  • 33
    • 76349117455 scopus 로고    scopus 로고
    • Androgen receptor in breast cancer: Expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation
    • Niemeier LA, Dabbs DJ, Beriwal S et al. Androgen receptor in breast cancer: Expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation. Mod Pathol 2009;23:205-212.
    • (2009) Mod Pathol , vol.23 , pp. 205-212
    • Niemeier, L.A.1    Dabbs, D.J.2    Beriwal, S.3
  • 34
    • 33745603978 scopus 로고    scopus 로고
    • An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen
    • Doane AS, Danso M, Lal P et al. An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene 2006;25: 3994-4008.
    • (2006) Oncogene , vol.25 , pp. 3994-4008
    • Doane, A.S.1    Danso, M.2    Lal, P.3
  • 35
    • 22744448864 scopus 로고    scopus 로고
    • Identification of molecular apocrine breast tumours by microarray analysis
    • Farmer P, Bonnefoi H, Becette V et al. Identification of molecular apocrine breast tumours by microarray analysis. Oncogene 2005;24:4660-4671.
    • (2005) Oncogene , vol.24 , pp. 4660-4671
    • Farmer, P.1    Bonnefoi, H.2    Becette, V.3
  • 36
    • 84858697828 scopus 로고    scopus 로고
    • TBCRC 011: Targeting the androgen receptor (AR) for the treatment of AR /ER /PR metastatic breast cancer (MBC)
    • Gucalp A, Tolaney SM, Isakoff SJ et al. TBCRC 011: Targeting the androgen receptor (AR) for the treatment of AR /ER /PR metastatic breast cancer (MBC). ASCO Meeting Abstracts 2011;29: TPS122.
    • (2011) ASCO Meeting Abstracts , vol.29
    • Gucalp, A.1    Tolaney, S.M.2    Isakoff, S.J.3
  • 37
    • 77954526150 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
    • Hammond MEH, Hayes DF, Dowsett M et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol 2010;28:2784-2795.
    • (2010) J Clin Oncol , vol.28 , pp. 2784-2795
    • Hammond, M.E.H.1    Hayes, D.F.2    Dowsett, M.3
  • 38
    • 84865125800 scopus 로고    scopus 로고
    • PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer
    • Prat A, Parker J, Fan C et al. PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer. Breast Cancer Res Treat 2012;135:301-306.
    • (2012) Breast Cancer Res Treat , vol.135 , pp. 301-306
    • Prat, A.1    Parker, J.2    Fan, C.3
  • 39
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • Herschkowitz JI, Simin K, Weigman VJ et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007;8:R76.
    • (2007) Genome Biol , vol.8
    • Herschkowitz, J.I.1    Simin, K.2    Weigman, V.J.3
  • 40
    • 79951871973 scopus 로고    scopus 로고
    • An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer
    • Katz E, Dubois-Marshall S, Sims AH et al. An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer. PLoS ONE 2011;6:e17083.
    • (2011) PLoS ONE , vol.6
    • Katz, E.1    Dubois-Marshall, S.2    Sims, A.H.3
  • 41
    • 84860304606 scopus 로고    scopus 로고
    • Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis
    • Walia V, Yu Y, Cao D et al. Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis. Oncogene 2012;31:2237-2246.
    • (2012) Oncogene , vol.31 , pp. 2237-2246
    • Walia, V.1    Yu, Y.2    Cao, D.3
  • 42
    • 84863129742 scopus 로고    scopus 로고
    • Dormant but migratory tumour cells in desmoplastic stroma of invasive ductal carcinomas
    • Raviraj V, Zhang H, Chien H-Y et al. Dormant but migratory tumour cells in desmoplastic stroma of invasive ductal carcinomas. Clin Exp Metastasis 2012;29:273-292.
    • (2012) Clin Exp Metastasis , vol.29 , pp. 273-292
    • Raviraj, V.1    Zhang, H.2    Chien, H.-Y.3
  • 43
    • 84874785183 scopus 로고    scopus 로고
    • A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudin-low human breast cancer
    • Epub ahead of print
    • Hollern DP, Yuwanita I, Andrechek ER. A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudin-low human breast cancer. Oncogene 2012 [Epub ahead of print].
    • (2012) Oncogene
    • Hollern, D.P.1    Yuwanita, I.2    Andrechek, E.R.3
  • 44
    • 84861398396 scopus 로고    scopus 로고
    • Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer
    • Xu K, Usary J, Kousis Philaretos C et al. Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. Cancer Cell 21:626-641.
    • Cancer Cell , vol.21 , pp. 626-641
    • Xu, K.1    Usary, J.2    Kousis, P.C.3
  • 45
    • 84862535875 scopus 로고    scopus 로고
    • Immunohistochemical features of claudin-low intrinsic subtype in metaplastic breast carcinomas
    • Gerhard R, Ricardo S, Albergaria A et al. Immunohistochemical features of claudin-low intrinsic subtype in metaplastic breast carcinomas. Breast 2012;21:354-360.
    • (2012) Breast , vol.21 , pp. 354-360
    • Gerhard, R.1    Ricardo, S.2    Albergaria, A.3
  • 46
    • 80053375746 scopus 로고    scopus 로고
    • Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor
    • Beltran A, Rivenbark A, Richardson B et al. Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor. Breast Cancer Res 2012;13:R94.
    • (2012) Breast Cancer Res , vol.13
    • Beltran, A.1    Rivenbark, A.2    Richardson, B.3
  • 47
    • 84863116790 scopus 로고    scopus 로고
    • Defining the cellular precursors to human breast cancer
    • Keller PJ, Arendt LM, Skibinski A et al. Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci 2012;109:2772-2777.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 2772-2777
    • Keller, P.J.1    Arendt, L.M.2    Skibinski, A.3
  • 48
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve R, Chin K, Fridlyand J et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006;10:515-527.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.1    Chin, K.2    Fridlyand, J.3
  • 49
    • 67650252530 scopus 로고    scopus 로고
    • Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
    • Kao J, Salari K, Bocanegra M et al. Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery. PLoS ONE 2009;4:e6146.
    • (2009) PLoS ONE , vol.4
    • Kao, J.1    Salari, K.2    Bocanegra, M.3
  • 50
    • 77951295615 scopus 로고    scopus 로고
    • Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines
    • Hollestelle A, Nagel J, Smid M et al. Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines. Breast Cancer Res Treat 2010;121:53-64.
    • (2010) Breast Cancer Res Treat , vol.121 , pp. 53-64
    • Hollestelle, A.1    Nagel, J.2    Smid, M.3
  • 51
    • 67651193848 scopus 로고    scopus 로고
    • T-cell metagene predicts a favourable prognosis in estrogen receptor negative and HER2 positive breast cancers
    • Rody A, Holtrich U, Pusztai L et al. T-cell metagene predicts a favourable prognosis in estrogen receptor negative and HER2 positive breast cancers. Breast Cancer Res 2009;11:R15.
    • (2009) Breast Cancer Res , vol.11
    • Rody, A.1    Holtrich, U.2    Pusztai, L.3
  • 52
    • 78650958088 scopus 로고    scopus 로고
    • Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures
    • Fan C, Prat A, Parker J et al. Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures. BMC Med Genomics 2011;4:3.
    • (2011) BMC Med Genomics , vol.4 , pp. 3
    • Fan, C.1    Prat, A.2    Parker, J.3
  • 53
    • 80755127904 scopus 로고    scopus 로고
    • The microenvironment in breast cancer progression: Biology and implications for treatment
    • Place A, Jin Huh S, Polyak K. The microenvironment in breast cancer progression: Biology and implications for treatment. Breast Cancer Res 2011; 13:227.
    • (2011) Breast Cancer Res , vol.13 , pp. 227
    • Place, A.1    Jin, H.S.2    Polyak, K.3
  • 54
    • 41449105551 scopus 로고    scopus 로고
    • HER2 status and benefit from adjuvant trastuzumab in breast cancer
    • Paik S, Kim C, Wolmark N. HER2 status and benefit from adjuvant trastuzumab in breast cancer. N Engl J Med 2008;358:1409-1411.
    • (2008) N Engl J Med , vol.358 , pp. 1409-1411
    • Paik, S.1    Kim, C.2    Wolmark, N.3
  • 56
    • 77949908546 scopus 로고    scopus 로고
    • Efficacy of neoadjuvant cisplatin in triple-negative breast cancer
    • Silver DP, Richardson AL, Eklund AC et al. Efficacy of neoadjuvant cisplatin in triple-negative breast cancer. J Clin Oncol 2010;28:1145-1153.
    • (2010) J Clin Oncol , vol.28 , pp. 1145-1153
    • Silver, D.P.1    Richardson, A.L.2    Eklund, A.C.3
  • 57
    • 79956329617 scopus 로고    scopus 로고
    • Tumor-infiltrating CD8 lymphocytes predict clinical outcome in breast cancer
    • Mahmoud SMA, Paish EC, Powe DG et al. Tumor-infiltrating CD8 lymphocytes predict clinical outcome in breast cancer. J Clin Oncol 2011;29: 1949-1955.
    • (2011) J Clin Oncol , vol.29 , pp. 1949-1955
    • Mahmoud, S.M.A.1    Paish, E.C.2    Powe, D.G.3
  • 58
    • 84862784272 scopus 로고    scopus 로고
    • CD8 lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer
    • Liu S, Lachapelle J, Leung S et al. CD8 lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer. Breast Cancer Res 2012;14:R48.
    • (2012) Breast Cancer Res , vol.14
    • Liu, S.1    Lachapelle, J.2    Leung, S.3
  • 59
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQM et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012;366:2455-2465.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.