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Volumn 41, Issue 4, 2012, Pages 1358-1364

Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules

Author keywords

Apoptosis; Honokiol; Human glioblastoma; Intercellular adhesion molecule 1; Metastasis; Vascular cell adhesion molecule 1

Indexed keywords

CELL ADHESION MOLECULE; HONOKIOL; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84866524759     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1582     Document Type: Article
Times cited : (33)

References (36)
  • 1
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY and Kesari S: Malignant gliomas in adults. N Engl J Med 359: 492-507, 2008.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 2
    • 0030778206 scopus 로고    scopus 로고
    • Molecular changes during the genesis of human gliomas
    • Sehgal A: Molecular changes during the genesis of human gliomas. Semin Surg Oncol 14: 3-12, 1998.
    • (1998) Semin Surg Oncol , vol.14 , pp. 3-12
    • Sehgal, A.1
  • 3
    • 0032893488 scopus 로고    scopus 로고
    • Current therapy for brain tumors: Back to the future
    • Shapiro WR: Current therapy for brain tumors: back to the future. Arch Neurol 56: 429-432, 1999.
    • (1999) Arch Neurol , vol.56 , pp. 429-432
    • Shapiro, W.R.1
  • 6
    • 0031872772 scopus 로고    scopus 로고
    • Behavioural pharmacological characteristics of honokiol, an anxiolytic agent present in extracts of Magnolia bark, evaluated by an elevated plus-maze test in mice
    • Kuribara H, Stavinoha WB and Maruyama Y: Behavioural pharmacological characteristics of honokiol, an anxiolytic agent present in extracts of Magnolia bark, evaluated by an elevated plus-maze test in mice. J Pharm Pharmacol 50: 819-826, 1998.
    • (1998) J Pharm Pharmacol , vol.50 , pp. 819-826
    • Kuribara, H.1    Stavinoha, W.B.2    Maruyama, Y.3
  • 7
    • 0031885496 scopus 로고    scopus 로고
    • Identification of magnolol and honokiol as anxiolytic agents in extracts of saiboku-to, an oriental herbal medicine
    • Maruyama Y, Kuribara H, Morita M, Yuzurihara M and Weintraub ST: Identification of magnolol and honokiol as anxiolytic agents in extracts of saiboku-to, an oriental herbal medicine. J Nat Prod 61: 135-138, 1998.
    • (1998) J Nat Prod , vol.61 , pp. 135-138
    • Maruyama, Y.1    Kuribara, H.2    Morita, M.3    Yuzurihara, M.4    Weintraub, S.T.5
  • 8
    • 0032977989 scopus 로고    scopus 로고
    • Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice
    • Kuribara H, Stavinoha WB and Maruyama Y: Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice. J Pharm Pharmacol 51: 97-103, 1999.
    • (1999) J Pharm Pharmacol , vol.51 , pp. 97-103
    • Kuribara, H.1    Stavinoha, W.B.2    Maruyama, Y.3
  • 10
    • 0021069340 scopus 로고
    • Pharmacological properties of magnolol and honokiol extracted from Magnolia officinalis: Central depressant effects
    • Watanabe K, Watanabe H, Goto Y, Yamaguchi M, Yamamoto N and Hagino K: Pharmacological properties of magnolol and honokiol extracted from Magnolia officinalis: central depressant effects. Planta Med 49: 103-108, 1983.
    • (1983) Planta Med , vol.49 , pp. 103-108
    • Watanabe, K.1    Watanabe, H.2    Goto, Y.3    Yamaguchi, M.4    Yamamoto, N.5    Hagino, K.6
  • 11
    • 0242391822 scopus 로고    scopus 로고
    • Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production
    • Liou KT, Shen YC, Chen CF, Tsao CM and Tsai SK: Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production. Brain Res 992: 159-166, 2003.
    • (2003) Brain Res , vol.992 , pp. 159-166
    • Liou, K.T.1    Shen, Y.C.2    Chen, C.F.3    Tsao, C.M.4    Tsai, S.K.5
  • 13
    • 0036569921 scopus 로고    scopus 로고
    • L, release of cytochrome c and sequential activation of caspases during honokiol induced apoptosis in human squamous lung cancer CH27 cells
    • L, release of cytochrome c and sequential activation of caspases during honokiol induced apoptosis in human squamous lung cancer CH27 cells. Biochem Pharmacol 63: 1641-1651, 2002.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1641-1651
    • Yang, S.E.1    Hsieh, M.T.2    Tsai, T.H.3    Hsu, S.L.4
  • 14
    • 4344633662 scopus 로고    scopus 로고
    • Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO
    • Wang T, Chen F, Chen Z, Wu YF, Xu XL, Zheng S and Hu X: Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO. World J Gastroenterol 10: 2205-2208, 2004.
    • (2004) World J Gastroenterol , vol.10 , pp. 2205-2208
    • Wang, T.1    Chen, F.2    Chen, Z.3    Wu, Y.F.4    Xu, X.L.5    Zheng, S.6    Hu, X.7
  • 15
    • 0028018410 scopus 로고
    • Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells
    • Hirano T, Gotoh M and Oka K: Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. Life Sci 55: 1061-1069, 1994.
    • (1994) Life Sci , vol.55 , pp. 1061-1069
    • Hirano, T.1    Gotoh, M.2    Oka, K.3
  • 16
    • 67651171652 scopus 로고    scopus 로고
    • Honokiol-mediated inhibition of PI3K/mTOR pathway: A potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function
    • Crane C, Panner A, Pieper RO, Arbiser J and Parsa AT: Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function. J Immunother 32: 585-592, 2009.
    • (2009) J Immunother , vol.32 , pp. 585-592
    • Crane, C.1    Panner, A.2    Pieper, R.O.3    Arbiser, J.4    Parsa, A.T.5
  • 17
    • 79955708703 scopus 로고    scopus 로고
    • Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model
    • Wang X, Duan X, Yang G, Zhang X, Deng L, Zheng H, Deng C, Wen J, Wang N, Peng C, Zhao X, Wei Y and Chen L: Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model. PLoS One 6: e18490, 2011.
    • (2011) PLoS One , vol.6
    • Wang, X.1    Duan, X.2    Yang, G.3    Zhang, X.4    Deng, L.5    Zheng, H.6    Deng, C.7    Wen, J.8    Wang, N.9    Peng, C.10    Zhao, X.11    Wei, Y.12    Chen, L.13
  • 18
    • 0028829282 scopus 로고
    • The increased expression of adhesion molecules ICAM-3, E-selectin and P-selectins on breast cancer endothelium
    • Fox SB, Turner GD, Gatter KC and Harris AL: The increased expression of adhesion molecules ICAM-3, E-selectin and P-selectins on breast cancer endothelium. J Pathol 177: 369-376, 1995.
    • (1995) J Pathol , vol.177 , pp. 369-376
    • Fox, S.B.1    Turner, G.D.2    Gatter, K.C.3    Harris, A.L.4
  • 19
    • 0031840361 scopus 로고    scopus 로고
    • Soluble vascular cell adhesion molecule-1 (sVCAM-1) is an independent prognostic marker in Hodgkin's disease
    • Christiansen I, Sundstrom C, Enblad G and Totterman TH: Soluble vascular cell adhesion molecule-1 (sVCAM-1) is an independent prognostic marker in Hodgkin's disease. Br J Haematol 102: 701-709, 1998.
    • (1998) Br J Haematol , vol.102 , pp. 701-709
    • Christiansen, I.1    Sundstrom, C.2    Enblad, G.3    Totterman, T.H.4
  • 20
    • 0344334069 scopus 로고    scopus 로고
    • Elevated serum levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) closely reflect tumour burden in chronic B-lymphocytic leukaemia
    • Christiansen I, Sundstrom C and Totterman TH: Elevated serum levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) closely reflect tumour burden in chronic B-lymphocytic leukaemia. Br J Haematol 103: 1129-1137, 1998.
    • (1998) Br J Haematol , vol.103 , pp. 1129-1137
    • Christiansen, I.1    Sundstrom, C.2    Totterman, T.H.3
  • 21
    • 0034265767 scopus 로고    scopus 로고
    • Serum ICAM-1 concentrations following conventional dose consolidation chemotherapy for acute myeloid leukemia and after high dose chemotherapy with autologous haematopoietic stem cell rescue
    • Wang X, Clowes C, Duarte R and Pu QQ: Serum ICAM-1 concentrations following conventional dose consolidation chemotherapy for acute myeloid leukemia and after high dose chemotherapy with autologous haematopoietic stem cell rescue. Int J Oncol 17: 591-595, 2000.
    • (2000) Int J Oncol , vol.17 , pp. 591-595
    • Wang, X.1    Clowes, C.2    Duarte, R.3    Pu, Q.Q.4
  • 23
    • 0026322355 scopus 로고
    • Shedding of ICAM-1 from human melanoma cell lines induced by IFN-gamma and tumor necrosis factor-alpha. Functional consequences on cell-mediated cytotoxicity
    • Becker JC, Dummer R, Hartmann AA, Burg G and Schmidt RE: Shedding of ICAM-1 from human melanoma cell lines induced by IFN-gamma and tumor necrosis factor-alpha. Functional consequences on cell-mediated cytotoxicity. J Immunol 147: 4398-4401, 1991.
    • (1991) J Immunol , vol.147 , pp. 4398-4401
    • Becker, J.C.1    Dummer, R.2    Hartmann, A.A.3    Burg, G.4    Schmidt, R.E.5
  • 24
    • 0024818401 scopus 로고
    • Direct expression cloning of vascular cell adhesion molecule-1, a cytokine-induced endothelial protein that binds to lymphocytes
    • Osborn L, Hession C, Tizard R, Vassallo C, Luhowskyj S, Chi-Rosso G and Lobb R: Direct expression cloning of vascular cell adhesion molecule-1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 59: 1203-1211, 1989.
    • (1989) Cell , vol.59 , pp. 1203-1211
    • Osborn, L.1    Hession, C.2    Tizard, R.3    Vassallo, C.4    Luhowskyj, S.5    Chi-Rosso, G.6    Lobb, R.7
  • 25
    • 0027982876 scopus 로고
    • Traffic signal for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer TA: Traffic signal for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314, 1994.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 26
    • 32344437926 scopus 로고    scopus 로고
    • Anthocyanins from soybean seed coat inhibit the expression of TNF-α-induced genes associated with ischemia/reperfusion in endothelial cell by NF-κB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo
    • Kim HJ, Tsoy I, Park JM, Chung JI, Shin SC and Chang KC: Anthocyanins from soybean seed coat inhibit the expression of TNF-α-induced genes associated with ischemia/reperfusion in endothelial cell by NF-κB- dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo. FEBS Lett 580: 1391-1397, 2006.
    • (2006) FEBS Lett , vol.580 , pp. 1391-1397
    • Kim, H.J.1    Tsoy, I.2    Park, J.M.3    Chung, J.I.4    Shin, S.C.5    Chang, K.C.6
  • 27
    • 33846649645 scopus 로고    scopus 로고
    • Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-κB signaling pathways
    • Nizamutdinova IT, Oh HM, Min YN, Park SH, Lee MJ, Kim JS, Yean MH, Kang SS, Kim YS, Chang KC and Kim HJ: Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-κB signaling pathways. Int Immunopharmacol 7: 343-350, 2007.
    • (2007) Int Immunopharmacol , vol.7 , pp. 343-350
    • Nizamutdinova, I.T.1    Oh, H.M.2    Min, Y.N.3    Park, S.H.4    Lee, M.J.5    Kim, J.S.6    Yean, M.H.7    Kang, S.S.8    Kim, Y.S.9    Chang, K.C.10    Kim, H.J.11
  • 28
    • 0032622190 scopus 로고    scopus 로고
    • Serum levels of soluble intercellular adhesion molecule-1 and E-selectin in metastatic breast carcinoma: Correlations with clinicopathological features and prognosis
    • Zhang GJ and Adachi I: Serum levels of soluble intercellular adhesion molecule-1 and E-selectin in metastatic breast carcinoma: correlations with clinicopathological features and prognosis. Int J Oncol 14: 71-77, 1999.
    • (1999) Int J Oncol , vol.14 , pp. 71-77
    • Zhang, G.J.1    Adachi, I.2
  • 29
    • 0036244198 scopus 로고    scopus 로고
    • Mechanisms of tumour invasion and metastasis: Emerging targets for therapy
    • Thompson EW and Price JT: Mechanisms of tumour invasion and metastasis: emerging targets for therapy. Expert Opin Ther Targets 6: 217-233, 2002.
    • (2002) Expert Opin Ther Targets , vol.6 , pp. 217-233
    • Thompson, E.W.1    Price, J.T.2
  • 30
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F and Mantovani A: Inflammation and cancer: back to Virchow? Lancet 357: 539-545, 2001.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 33
    • 0345276414 scopus 로고    scopus 로고
    • Bcl-2 family proteins and the role of mitochondria in apoptosis
    • Kuwana T and Newmeyer DD: Bcl-2 family proteins and the role of mitochondria in apoptosis. Curr Opin Cell Biol 15: 691-699, 2003.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 691-699
    • Kuwana, T.1    Newmeyer, D.D.2
  • 35
    • 34347393710 scopus 로고    scopus 로고
    • High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers
    • Klemke M, Weschenfelder T, Konstandin MH and Samstag Y: High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers. J Cell Physiol 212: 368-374, 2007.
    • (2007) J Cell Physiol , vol.212 , pp. 368-374
    • Klemke, M.1    Weschenfelder, T.2    Konstandin, M.H.3    Samstag, Y.4
  • 36
    • 34447120196 scopus 로고    scopus 로고
    • The role of vascular cell adhesion molecule-1 in tumor immune evasion
    • Wu TC: The role of vascular cell adhesion molecule-1 in tumor immune evasion. Cancer Res 67: 6003-6006, 2007.
    • (2007) Cancer Res , vol.67 , pp. 6003-6006
    • Wu, T.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.