Systematic dissection of genomic features determining transcription factor binding and enhancer function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 7, 2017, Pages E1291-E1300

  Grossman, Sharon R ^a,b,c   Zhang, Xiaolan ^a   Wang, Li ^a   Engreitz, Jesse ^a,b   Melnikov, Alexandre ^a   Rogov, Peter ^a   Tewhey, Ryan ^a,d,e   Isakova, Alina ^f,g   Deplancke, Bart ^f,g   Bernstein, Bradley E ^a,h   Mikkelsen, Tarjei S ^a,i,j   Lander, Eric S ^a,b,c  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD UNIVERSITY   (United States)

^e HARVARD UNIVERSITY   (United States)

^f Institute of Bioengineering   (Switzerland)

^g SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

ⁱ HARVARD STEM CELL INSTITUTE   (United States)

^j Harvard University   (United States)

more..

Author keywords

Gene regulation; Systems biology; Transcription factor binding

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN; DNA; FORKHEAD BOX PROTEIN O4; FORKHEAD TRANSCRIPTION FACTOR; LIVER X RECEPTOR; NUCLEAR FACTOR I; OLIGONUCLEOTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; PROTEIN BINDING;

3T3 CELL LINE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CELL FATE; CHROMATIN; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GENE CONTROL; GENE EXPRESSION; GENOMICS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; 3T3-L1 CELL LINE; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; NUCLEOTIDE MOTIF; PROCEDURES;

3T3-L1 CELLS; ANIMALS; BINDING SITES; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENOMICS; MICE; MUTATION; NUCLEOTIDE MOTIFS; PPAR GAMMA; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 85013031848     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1621150114     Document Type: Article

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