Quantification of cooperativity in heterodimer-DNA binding improves the accuracy of binding specificity models

Journal of Biological Chemistry

Volumn 291, Issue 19, 2016, Pages 10293-10306

  Isakova, Alina ^a,b   Berset, Yves ^a,b   Hatzimanikatis, Vassily ^a,b   Deplancke, Bart ^a,b  

^a EPFL   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIORAL RESEARCH; BINDING SITES; BINS; BIOMOLECULES; CYTOLOGY; DIMERS; PROTEINS; TRANSCRIPTION;

BINDING SPECIFICITIES; DNA BINDING CONSTANT; DNA-BINDING SPECIFICITY; MECHANISTIC MODELING; NUCLEOTIDE SUBSTITUTION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROTEIN-DNA INTERACTIONS; RETINOID X RECEPTOR;

DNA;

DNA; HETERODIMER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR ALPHA;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; MECHANICALLY INDUCED TRAPPING OF MOLECULAR INTERACTION; MICROFLUIDICS; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE BINDING SITE; PHYSICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; BINDING SITE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR MODEL; PROTEIN MULTIMERIZATION;

BINDING SITES; DNA; HUMANS; MODELS, MOLECULAR; PPAR GAMMA; PROTEIN MULTIMERIZATION; RETINOID X RECEPTOR ALPHA;

EID: 84966333766     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.691154     Document Type: Article

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