In vitro reconstruction of nonribosomal peptide biosynthesis directly from DNA using cell-free protein synthesis

ACS Synthetic Biology

Volumn 6, Issue 1, 2017, Pages 39-44

  Goering, Anthony W ^a,b   Li, Jian ^c   McClure, Ryan A ^a,b   Thomson, Regan J ^a   Jewett, Michael C ^c   Kelleher, Neil L ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Northwestern University   (India)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Biosynthesis; Cell Free Protein Synthesis; Cyclic Dipeptide; Diketopiperazine; Natural Products; Synthetic Biology

Indexed keywords

BACTERIAL DNA; DIPEPTIDE; NONRIBOSOMAL PEPTIDE SYNTHETASE; PIPERAZINEDIONE; CYCLOPEPTIDE; DNA; GRAMICIDIN; PEPTIDE SYNTHASE; PHENYLALANYL-PROLYL DIKETOPIPERAZINE; PIPERAZINE DERIVATIVE;

ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; ESCHERICHIA COLI; IN VITRO STUDY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; NONHUMAN; NONRIBOSOMAL PEPTIDE SYNTHESIS; ONE POT SYNTHESIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; STANDARD; STEREOCHEMISTRY; BIOSYNTHESIS; CHEMISTRY; GENETICS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; SYNTHETIC BIOLOGY;

BIOSYNTHETIC PATHWAYS; CELL-FREE SYSTEM; CHROMATOGRAPHY, LIQUID; DIPEPTIDES; DNA; ESCHERICHIA COLI; GRAMICIDIN; IN VITRO TECHNIQUES; MASS SPECTROMETRY; PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT; PEPTIDE SYNTHASES; PEPTIDES, CYCLIC; PIPERAZINES; SYNTHETIC BIOLOGY;

EID: 85012824047     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.6b00160     Document Type: Article

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