-
1
-
-
84887496305
-
An endogenous factor mediates shock-induced injury
-
Ward PA: An endogenous factor mediates shock-induced injury. Nat Med 2013; 19: 1368-1369.
-
(2013)
Nat Med
, vol.19
, pp. 1368-1369
-
-
Ward, P.A.1
-
2
-
-
0023217633
-
Modulation of acute immune complex-mediated tissue injury by the presence of polyionic substances
-
Warren JS, Ward PA, Johnson KJ, Ginsburg I: Modulation of acute immune complex-mediated tissue injury by the presence of polyionic substances. Am J Pathol 1987; 128: 67-77.
-
(1987)
Am J Pathol
, vol.128
, pp. 67-77
-
-
Warren, J.S.1
Ward, P.A.2
Johnson, K.J.3
Ginsburg, I.4
-
3
-
-
0024453722
-
Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide
-
Ginsburg I, Gibbs DF, Schuger L, Johnson KJ, Ryan US, Ward PA, Varani J: Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide. Free Radic Biol Med 1989; 7: 369-376.
-
(1989)
Free Radic Biol Med
, vol.7
, pp. 369-376
-
-
Ginsburg, I.1
Gibbs, D.F.2
Schuger, L.3
Johnson, K.J.4
Ryan, U.S.5
Ward, P.A.6
Varani, J.7
-
4
-
-
0026785080
-
Synergism among oxidants, proteinases, phospholipases, microbial hemolysins, cationic proteins, and cytokines
-
Ginsburg I, Misgav R, Pinson A, Varani J, Ward PA, Kohen R: Synergism among oxidants, proteinases, phospholipases, microbial hemolysins, cationic proteins, and cytokines. Inflammation 1992; 16: 519-538.
-
(1992)
Inflammation
, vol.16
, pp. 519-538
-
-
Ginsburg, I.1
Misgav, R.2
Pinson, A.3
Varani, J.4
Ward, P.A.5
Kohen, R.6
-
5
-
-
84865299726
-
PAMPs and DAMPs: Signal 0s that spur autophagy and immunity
-
Tang D, Kang R, Coyne CB, Zeh HJ, Lotze MT: PAMPs and DAMPs: Signal 0s that spur autophagy and immunity. Immunol Rev 2012; 249: 158-175.
-
(2012)
Immunol Rev
, vol.249
, pp. 158-175
-
-
Tang, D.1
Kang, R.2
Coyne, C.B.3
Zeh, H.J.4
Lotze, M.T.5
-
6
-
-
84880108827
-
Selective roles for toll-like receptors 2, 4, and 9 in systemic inflammation and immune dysfunction following peripheral tissue injury
-
Darwiche SS, Ruan X, Hoffman MK, Zettel KR, Tracy AP, Schroeder LM, Cai C, Hoffman RA, Scott MJ, Pape HC, Billiar TR: Selective roles for toll-like receptors 2, 4, and 9 in systemic inflammation and immune dysfunction following peripheral tissue injury. J Trauma Acute Care Surg 2013; 74: 1454-1461.
-
(2013)
J Trauma Acute Care Surg
, vol.74
, pp. 1454-1461
-
-
Darwiche, S.S.1
Ruan, X.2
Hoffman, M.K.3
Zettel, K.R.4
Tracy, A.P.5
Schroeder, L.M.6
Cai, C.7
Hoffman, R.A.8
Scott, M.J.9
Pape, H.C.10
Billiar, T.R.11
-
7
-
-
80051884192
-
Extracellular histones promote thrombin generation through platelet-dependent mechanisms: Involvement of platelet TLR2 and TLR4
-
Semeraro F, Ammollo CT, Morrissey JH, Dale GL, Friese P, Esmon NL, Esmon CT: Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4. Blood 2011; 118: 1952-1961.
-
(2011)
Blood
, vol.118
, pp. 1952-1961
-
-
Semeraro, F.1
Ammollo, C.T.2
Morrissey, J.H.3
Dale, G.L.4
Friese, P.5
Esmon, N.L.6
Esmon, C.T.7
-
8
-
-
80051882006
-
Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
-
Xu J, Zhang X, Monestier M, Esmon NL, Esmon CT: Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury. J Immunol 2011; 187: 2626-2631.
-
(2011)
J Immunol
, vol.187
, pp. 2626-2631
-
-
Xu, J.1
Zhang, X.2
Monestier, M.3
Esmon, N.L.4
Esmon, C.T.5
-
9
-
-
84864849535
-
Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4
-
Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hagele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ: Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. J Am Soc Nephrol 2012; 23: 1375-1388.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1375-1388
-
-
Allam, R.1
Scherbaum, C.R.2
Darisipudi, M.N.3
Mulay, S.R.4
Hagele, H.5
Lichtnekert, J.6
Hagemann, J.H.7
Rupanagudi, K.V.8
Ryu, M.9
Schwarzenberger, C.10
Hohenstein, B.11
Hugo, C.12
Uhl, B.13
Reichel, C.A.14
Krombach, F.15
Monestier, M.16
Liapis, H.17
Moreth, K.18
Schaefer, L.19
Anders, H.J.20
more..
-
10
-
-
84872555329
-
Circulating histones are mediators of trauma-associated lung injury
-
Abrams ST, Zhang N, Manson J, Liu T, Dart C, Baluwa F, Wang SS, Brohi K, Kipar A, Yu W, Wang G, Toh CH: Circulating histones are mediators of trauma-associated lung injury. Am J Respir Crit Care Med 2013; 187: 160-169.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 160-169
-
-
Abrams, S.T.1
Zhang, N.2
Manson, J.3
Liu, T.4
Dart, C.5
Baluwa, F.6
Wang, S.S.7
Brohi, K.8
Kipar, A.9
Yu, W.10
Wang, G.11
Toh, C.H.12
-
13
-
-
84863548610
-
Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury
-
Caudrillier A, Kessenbrock K, Gilliss BM, Nguyen JX, Marques MB, Monestier M, Toy P, Werb Z, Looney MR: Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury. J Clin Invest 2012; 122: 2661-2671.
-
(2012)
J Clin Invest
, vol.122
, pp. 2661-2671
-
-
Caudrillier, A.1
Kessenbrock, K.2
Gilliss, B.M.3
Nguyen, J.X.4
Marques, M.B.5
Monestier, M.6
Toy, P.7
Werb, Z.8
Looney, M.R.9
-
14
-
-
84884752631
-
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism
-
Nakahara M, Ito T, Kawahara K, Yamamoto M, Nagasato T, Shrestha B, Yamada S, Miyauchi T, Higuchi K, Takenaka T, Yasuda T, Matsunaga A, Kakihana Y, Hashiguchi T, Kanmura Y, Maruyama I: Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism. PLoS One 2013; 8:e75961.
-
(2013)
PLoS One
, vol.8
, pp. e75961
-
-
Nakahara, M.1
Ito, T.2
Kawahara, K.3
Yamamoto, M.4
Nagasato, T.5
Shrestha, B.6
Yamada, S.7
Miyauchi, T.8
Higuchi, K.9
Takenaka, T.10
Yasuda, T.11
Matsunaga, A.12
Kakihana, Y.13
Hashiguchi, T.14
Kanmura, Y.15
Maruyama, I.16
-
15
-
-
84890506255
-
Extracellular histones are essential effectors of C5aR-and C5L2-mediated tissue damage and inflammation in acute lung injury
-
Bosmann M, Grailer JJ, Ruemmler R, Russkamp NF, Zetoune FS, Sarma JV, Standiford TJ, Ward PA: Extracellular histones are essential effectors of C5aR-and C5L2-mediated tissue damage and inflammation in acute lung injury. FASEB J 2013; 27: 5010-5021.
-
(2013)
FASEB J
, vol.27
, pp. 5010-5021
-
-
Bosmann, M.1
Grailer, J.J.2
Ruemmler, R.3
Russkamp, N.F.4
Zetoune, F.S.5
Sarma, J.V.6
Standiford, T.J.7
Ward, P.A.8
-
16
-
-
70449107044
-
Extracellular histones are major mediators of death in sepsis
-
Xu J, Zhang X, Pelayo R, Monestier M, Ammollo CT, Semeraro F, Taylor FB, Esmon NL, Lupu F, Esmon CT: Extracellular histones are major mediators of death in sepsis. Nat Med 2009; 15: 1318-1321.
-
(2009)
Nat Med
, vol.15
, pp. 1318-1321
-
-
Xu, J.1
Zhang, X.2
Pelayo, R.3
Monestier, M.4
Ammollo, C.T.5
Semeraro, F.6
Taylor, F.B.7
Esmon, N.L.8
Lupu, F.9
Esmon, C.T.10
-
17
-
-
84863122657
-
Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction
-
Gillrie MR, Lee K, Gowda DC, Davis SP, Monestier M, Cui L, Hien TT, Day NP, Ho M: Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction. Am J Pathol 2012; 180: 1028-1039.
-
(2012)
Am J Pathol
, vol.180
, pp. 1028-1039
-
-
Gillrie, M.R.1
Lee, K.2
Gowda, D.C.3
Davis, S.P.4
Monestier, M.5
Cui, L.6
Hien, T.T.7
Day, N.P.8
Ho, M.9
-
18
-
-
84857591047
-
Neutrophil extracellular traps directly induce epithelial and endothelial cell death: A predominant role of histones
-
Saffarzadeh M, Juenemann C, Queisser MA, Lochnit G, Barreto G, Galuska SP, Lohmeyer J, Preissner KT: Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. PLoS One 2012; 7:e32366.
-
(2012)
PLoS One
, vol.7
, pp. e32366
-
-
Saffarzadeh, M.1
Juenemann, C.2
Queisser, M.A.3
Lochnit, G.4
Barreto, G.5
Galuska, S.P.6
Lohmeyer, J.7
Preissner, K.T.8
-
19
-
-
84964313704
-
Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation
-
Ekaney ML, Otto GP, Sossdorf M, Sponholz C, Boehringer M, Loesche W, Rittirsch D, Wilharm A, Kurzai O, Bauer M, Claus RA: Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation. Crit Care 2014; 18: 543.
-
(2014)
Crit Care
, vol.18
, pp. 543
-
-
Ekaney, M.L.1
Otto, G.P.2
Sossdorf, M.3
Sponholz, C.4
Boehringer, M.5
Loesche, W.6
Rittirsch, D.7
Wilharm, A.8
Kurzai, O.9
Bauer, M.10
Claus, R.A.11
-
20
-
-
0000220470
-
Bactericidal action of histone
-
Hirsch JG: Bactericidal action of histone. J Exp Med 1958; 108: 925-944.
-
(1958)
J Exp Med
, vol.108
, pp. 925-944
-
-
Hirsch, J.G.1
-
21
-
-
84902199760
-
Critical role for the NLRP3 inflammasome during acute lung injury
-
Grailer JJ, Canning BA, Kalbitz M, Haggadone MD, Dhond RM, Andjelkovic AV, Zetoune FS, Ward PA: Critical role for the NLRP3 inflammasome during acute lung injury. J Immunol 2014; 192: 5974-5983.
-
(2014)
J Immunol
, vol.192
, pp. 5974-5983
-
-
Grailer, J.J.1
Canning, B.A.2
Kalbitz, M.3
Haggadone, M.D.4
Dhond, R.M.5
Andjelkovic, A.V.6
Zetoune, F.S.7
Ward, P.A.8
-
22
-
-
47249136130
-
Histone modifications and nuclear architecture: A review
-
Bartova E, Krejci J, Harnicarova A, Galiova G, Kozubek S: Histone modifications and nuclear architecture: a review. J Histochem Cytochem 2008; 56: 711-721.
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 711-721
-
-
Bartova, E.1
Krejci, J.2
Harnicarova, A.3
Galiova, G.4
Kozubek, S.5
-
23
-
-
84925708107
-
Post-translational modifications of histones that influence nucleosome dynamics
-
Bowman GD, Poirier MG: Post-translational modifications of histones that influence nucleosome dynamics. Chem Rev 2015; 115: 2274-2295.
-
(2015)
Chem Rev
, vol.115
, pp. 2274-2295
-
-
Bowman, G.D.1
Poirier, M.G.2
-
24
-
-
70149086262
-
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
-
Jones JE, Causey CP, Knuckley B, Slack-Noyes JL, Thompson PR: Protein arginine deiminase 4 (PAD4): current understanding and future therapeutic potential. Curr Opin Drug Discov Dev 2009; 12: 616-627.
-
(2009)
Curr Opin Drug Discov Dev
, vol.12
, pp. 616-627
-
-
Jones, J.E.1
Causey, C.P.2
Knuckley, B.3
Slack-Noyes, J.L.4
Thompson, P.R.5
-
25
-
-
0022548913
-
Antihistone antibodies detected by ELISA and immunoblotting in systemic lupus erythematosus and rheumatoid arthritis
-
Costa O, Monier JC: Antihistone antibodies detected by ELISA and immunoblotting in systemic lupus erythematosus and rheumatoid arthritis. J Rheumatol 1986; 13: 722-725.
-
(1986)
J Rheumatol
, vol.13
, pp. 722-725
-
-
Costa, O.1
Monier, J.C.2
-
26
-
-
84861465962
-
Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis
-
Sokolove J, Bromberg R, Deane KD, Lahey LJ, Derber LA, Chandra PE, Edison JD, Gilliland WR, Tibshirani RJ, Norris JM, Holers VM, Robinson WH: Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis. PLoS One 2012; 7:e35296.
-
(2012)
PLoS One
, vol.7
, pp. e35296
-
-
Sokolove, J.1
Bromberg, R.2
Deane, K.D.3
Lahey, L.J.4
Derber, L.A.5
Chandra, P.E.6
Edison, J.D.7
Gilliland, W.R.8
Tibshirani, R.J.9
Norris, J.M.10
Holers, V.M.11
Robinson, W.H.12
-
27
-
-
34347400796
-
Regulation of toll-like receptor-mediated inflammatory response by complement in vivo
-
Zhang X, Kimura Y, Fang C, Zhou L, Sfyroera G, Lambris JD, Wetsel RA, Miwa T, Song WC: Regulation of toll-like receptor-mediated inflammatory response by complement in vivo. Blood 2007; 110: 228-236.
-
(2007)
Blood
, vol.110
, pp. 228-236
-
-
Zhang, X.1
Kimura, Y.2
Fang, C.3
Zhou, L.4
Sfyroera, G.5
Lambris, J.D.6
Wetsel, R.A.7
Miwa, T.8
Song, W.C.9
-
28
-
-
84906939114
-
Persistent neutrophil dysfunction and suppression of acute lung injury in mice following cecal ligation and puncture sepsis
-
Grailer JJ, Kalbitz M, Zetoune FS, Ward PA: Persistent neutrophil dysfunction and suppression of acute lung injury in mice following cecal ligation and puncture sepsis. J Innate Immun 2014; 6: 695-705.
-
(2014)
J Innate Immun
, vol.6
, pp. 695-705
-
-
Grailer, J.J.1
Kalbitz, M.2
Zetoune, F.S.3
Ward, P.A.4
-
29
-
-
84876847543
-
CD11c+ alveolar macrophages are a source of IL-23 during lipopolysaccharide-induced acute lung injury
-
Bosmann M, Grailer JJ, Russkamp NF, Ruemmler R, Zetoune FS, Sarma JV, Ward PA: CD11c+ alveolar macrophages are a source of IL-23 during lipopolysaccharide-induced acute lung injury. Shock 2013; 39: 447-452.
-
(2013)
Shock
, vol.39
, pp. 447-452
-
-
Bosmann, M.1
Grailer, J.J.2
Russkamp, N.F.3
Ruemmler, R.4
Zetoune, F.S.5
Sarma, J.V.6
Ward, P.A.7
-
30
-
-
0032850282
-
The adrenoceptor agonist clenbuterol is a potent inhibitor of the LPSinduced production of TNF-? And IL-6 in vitro and in vivo
-
Izeboud CA, Monshouwer M, van Miert AS, Witkamp RF: The adrenoceptor agonist clenbuterol is a potent inhibitor of the LPSinduced production of TNF-? and IL-6 in vitro and in vivo. Inflamm Res 1999; 48: 497-502.
-
(1999)
Inflamm Res
, vol.48
, pp. 497-502
-
-
Izeboud, C.A.1
Monshouwer, M.2
Van Miert, A.S.3
Witkamp, R.F.4
-
31
-
-
0035930414
-
Differential upregulation of TNF-?, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model
-
Sugita-Konishi Y, Pestka JJ: Differential upregulation of TNF-?, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. J Toxicol Environ Health A 2001; 64: 619-636.
-
(2001)
J Toxicol Environ Health A
, vol.64
, pp. 619-636
-
-
Sugita-Konishi, Y.1
Pestka, J.J.2
-
32
-
-
33847689914
-
Optimized THP-1 differentiation is required for the detection of responses to weak stimuli
-
Park EK, Jung HS, Yang HI, Yoo MC, Kim C, Kim KS: Optimized THP-1 differentiation is required for the detection of responses to weak stimuli. Inflamm Res 2007; 56: 45-50.
-
(2007)
Inflamm Res
, vol.56
, pp. 45-50
-
-
Park, E.K.1
Jung, H.S.2
Yang, H.I.3
Yoo, M.C.4
Kim, C.5
Kim, K.S.6
-
33
-
-
22044441502
-
A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats
-
Hofstetter C, Flondor M, Boost KA, Koehler P, Bosmann M, Pfeilschifter J, Zwissler B, Muhl H: A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats. Int Immunopharmacol 2005; 5: 1519-1522.
-
(2005)
Int Immunopharmacol
, vol.5
, pp. 1519-1522
-
-
Hofstetter, C.1
Flondor, M.2
Boost, K.A.3
Koehler, P.4
Bosmann, M.5
Pfeilschifter, J.6
Zwissler, B.7
Muhl, H.8
-
34
-
-
84868383632
-
Na +, K +-ATPase: Ubiquitous multifunctional transmembrane protein and its relevance to various pathophysiological conditions
-
Suhail M: Na +, K +-ATPase: ubiquitous multifunctional transmembrane protein and its relevance to various pathophysiological conditions. J Clin Med Res 2010; 2: 1-17.
-
(2010)
J Clin Med Res
, vol.2
, pp. 1-17
-
-
Suhail, M.1
-
35
-
-
0035863922
-
Role of C5a in multiorgan failure during sepsis
-
Huber-Lang M, Sarma VJ, Lu KT, McGuire SR, Padgaonkar VA, Guo RF, Younkin EM, Kunkel RG, Ding J, Erickson R, Curnutte JT, Ward PA: Role of C5a in multiorgan failure during sepsis. J Immunol 2001; 166: 1193-1199.
-
(2001)
J Immunol
, vol.166
, pp. 1193-1199
-
-
Huber-Lang, M.1
Sarma, V.J.2
Lu, K.T.3
McGuire, S.R.4
Padgaonkar, V.A.5
Guo, R.F.6
Younkin, E.M.7
Kunkel, R.G.8
Ding, J.9
Erickson, R.10
Curnutte, J.T.11
Ward, P.A.12
-
36
-
-
84874509753
-
Current trends in inflammatory and immunomodulatory mediators in sepsis
-
Aziz M, Jacob A, Yang WL, Matsuda A, Wang P: Current trends in inflammatory and immunomodulatory mediators in sepsis. J Leukoc Biol 2013; 93: 329-342.
-
(2013)
J Leukoc Biol
, vol.93
, pp. 329-342
-
-
Aziz, M.1
Jacob, A.2
Yang, W.L.3
Matsuda, A.4
Wang, P.5
-
37
-
-
84934933688
-
Role of extracellular histones in the cardiomyopathy of sepsis
-
Kalbitz M, Grailer JJ, Fattahi F, Jajou L, Herron TJ, Campbell KF, Zetoune FS, Bosmann M, Sarma JV, Huber-Lang M, Gebhard F, Loaiza R, Valdivia HH, Jalife J, Russell MW, Ward PA: Role of extracellular histones in the cardiomyopathy of sepsis. FASEB J 2015; 29: 2185-2193.
-
(2015)
FASEB J
, vol.29
, pp. 2185-2193
-
-
Kalbitz, M.1
Grailer, J.J.2
Fattahi, F.3
Jajou, L.4
Herron, T.J.5
Campbell, K.F.6
Zetoune, F.S.7
Bosmann, M.8
Sarma, J.V.9
Huber-Lang, M.10
Gebhard, F.11
Loaiza, R.12
Valdivia, H.H.13
Jalife, J.14
Russell, M.W.15
Ward, P.A.16
-
38
-
-
84941924101
-
Circulating histones are major mediators of cardiac injury in patients with sepsis
-
Alhamdi Y, Abrams ST, Cheng Z, Jing S, Su D, Liu Z, Lane S, Welters I, Wang G, Toh CH: Circulating histones are major mediators of cardiac injury in patients with sepsis. Crit Care Med 2015; 43: 2094-2103.
-
(2015)
Crit Care Med
, vol.43
, pp. 2094-2103
-
-
Alhamdi, Y.1
Abrams, S.T.2
Cheng, Z.3
Jing, S.4
Su, D.5
Liu, Z.6
Lane, S.7
Welters, I.8
Wang, G.9
Toh, C.H.10
-
39
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y, Zychlinsky A: Neutrophil extracellular traps kill bacteria. Science 2004; 303: 1532-1535.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
Fauler, B.4
Uhlemann, Y.5
Weiss, D.S.6
Weinrauch, Y.7
Zychlinsky, A.8
-
40
-
-
84925521952
-
Organ distribution of histones after intravenous infusion of FITC histones or after sepsis
-
Fattahi F, Grailer JJ, Jajou L, Zetoune FS, Andjelkovic AV, Ward PA: Organ distribution of histones after intravenous infusion of FITC histones or after sepsis. Immunol Res 2015; 61: 177-186.
-
(2015)
Immunol Res
, vol.61
, pp. 177-186
-
-
Fattahi, F.1
Grailer, J.J.2
Jajou, L.3
Zetoune, F.S.4
Andjelkovic, A.V.5
Ward, P.A.6
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