Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

eLife

Volumn 5, Issue DECEMBER2016, 2016, Pages

  Lebensohn, Andres M ^a   Dubey, Ramin ^a   Neitzel, Leif R ^b   Tacchelly Benites, Ofelia ^c   Yang, Eungi ^c   Marceau, Caleb D ^a   Davis, Eric M ^d   Patel, Bhaven B ^a   Bahrami Nejad, Zahra ^a   Travaglini, Kyle J ^a   Ahmed, Yashi ^c   Lee, Ethan ^b   Carette, Jan E ^a   Rohatgi, Rajat ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; APC PROTEIN; AXIN; BETA CATENIN; CASEIN KINASE IALPHA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DISRUPTOR OF TELOMERIC SILENCING 1 LIKE PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PEPTIDES AND PROTEINS; PROTEIN BCL 9; RING FINGER PROTEIN 43; TRANSCRIPTION FACTOR AP 4; UNCLASSIFIED DRUG; WNT3A PROTEIN; ZINC AND RING FINGER 3; APC2 PROTEIN, HUMAN; CASEIN KINASE I; CYTOSKELETON PROTEIN; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; CRISPR CAS SYSTEM; EPISTASIS; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC REGULATION; GENETIC SCREENING; GENOTYPE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOUSE; MUTAGENESIS; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; WNT SIGNALING PATHWAY; DEFICIENCY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; HAPLOIDY; HUMAN; METABOLISM; PROCEDURES; REPORTER GENE; WNT SIGNALING;

CASEIN KINASE I; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENES, REPORTER; GENETIC TESTING; HAPLOIDY; HUMANS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 85011697979     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.21459     Document Type: Article

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