The overexpression of AP-4 as a prognostic indicator for gastric carcinoma

Medical Oncology

Volumn 29, Issue 2, 2012, Pages 871-877

  Xinghua, Liu ^a   Bo, Zhang ^a   Yan, Guo ^b   Lei, Wu ^a   Changyao, Wu ^a   Qi, Liang ^a   Lin, Ye ^a   Kaixiong, Tao ^a   Guobin, Wang ^a   Jianying, Chen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

AP 4; Correlation; Gastric cancer; Overexpressed; Prognosis

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 4; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; ENHANCER BINDING PROTEIN AP 4; ENHANCER-BINDING PROTEIN AP-4; MESSENGER RNA; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CANCER; TUMOR DIFFERENTIATION; CASE CONTROL STUDY; COMPARATIVE STUDY; ENZYME IMMUNOASSAY; FOLLOW UP; GENETICS; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH; STOMACH TUMOR; SURVIVAL RATE;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DNA-BINDING PROTEINS; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STOMACH; STOMACH NEOPLASMS; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84864881930     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-011-9845-8     Document Type: Article

References (37)

1. Correia M, Machado JC, Ristimaki A. Basic aspects of gastric cancer. Helicobacter. 2009;14(Suppl 1):36-40.
2. Wu K, Nie Y, Guo C, Chen Y, Ding J, Fan D. Molecular basis of therapeutic approaches to gastric cancer. J Gastroenterol Hepatol. 2009;24(1):37-41.
3. Catalano V, Labianca R, Beretta GD, Gatta G, de Braud F, Van Cutsem E. Gastric cancer. Crit Rev Oncol Hematol. 2009;71(2): 127-64.
4. Jones S. An overview of the basic helix-loop-helix proteins. Genome Biol. 2004;5(6):226.
5. Massari ME, Murre C. Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol Cell Biol. 2000; 20(2):429-40.
6. Grau R, Punzon C, Fresno M, Iniguez MA. Peroxisome-proliferator- activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1. Biochem J. 2006;395(1):81-8.
7. Atchley WR, Fitch WM. A natural classification of the basic helix-loop-helix class of transcription factors. Proc Natl Acad Sci USA. 1997;94(10):5172-6.
8. Lee SU, Song HO, Lee W, Singaravelu G, Yu JR, Park WY. Identification and characterization of a putative basic helix-loophelix (bHLH) transcription factor interacting with calcineurin in C. elegans. Mol Cells. 2009;28(5):455-61.
9. Mermod N, Williams TJ, Tjian R. Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro. Nature. 1988;332(6164):557-61.
10. Hu YF, Luscher B, Admon A, Mermod N, Tjian R. Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev. 1990;4(10):1741-52.
11. Jung P, Menssen A, Mayr D, Hermeking H. AP4 encodes a c-MYC-inducible repressor of p21. Proc Natl Acad Sci USA. 2008;105(39):15046-51.
12. Jung P, Hermeking H. The c-MYC-AP4-p21 cascade. Cell Cycle. 2009;8(7):982-9.
13. Cui Y, Narayanan CS, Zhou J, Kumar A. Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression. Gene. 1998;224(1-2):97-107.
14. Wang R, Zhang YW, Zhang X, Liu R, Hong S, Xia K, et al. Transcriptional regulation of APH-1A and increased gammasecretase cleavage of APP and Notch by HIF-1 and hypoxia. FASEB J. 2006;20(8):1275-7.
15. Tsujimoto K, Ono T, Sato M, Nishida T, Oguma T, Tadakuma T. Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis. J Biol Chem. 2005;280(30):27638-44.
16. Kim MY, Jeong BC, Lee JH, Kee HJ, Kook H, Kim NS, et al. A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. Proc Natl Acad Sci USA. 2006;103(35):13074-9.
17. Unk I, Kiss-Toth E, Boros I. Transcription factor AP-4 participates in activation of bovine leukemia virus long terminal repeat by p34 tax. Nucleic Acids Res. 1994;22(23):4872-5.
18. Glahder JA, Hansen CN, Vinther J, Madsen BS, Norrild B. A promoter within the E6 ORF of human papillomavirus type 16 contributes to the expression of the E7 oncoprotein from a monocistronic mRNA. J Gen Virol. 2003;84(Pt 12):3429-41.
19. Fodor E, Weinrich SL, Meister A, Mermod N, Rutter WJ. A pancreatic exocrine cell factor and AP4 bind overlapping sites in the amylase 2A enhancer. Biochemistry. 1991;30(33):8102-8.
20. Cao J, Tang M, Li WL, Xie J, Du H, Tang WB, et al. Upregulation of activator protein-4 in human colorectal cancer with metastasis. Int J Surg Pathol. 2009;17(1):16-21.
21. Lin TX, Huang J, Huang H, Cai QQ, Xu KW, Yin XB, et al. Identification of response element gene sequence for non-steroid hormone transcription factors for the activation and up-regulation of L-plastin expression in prostate cancer. Zhonghua Nan Ke Xue. 2005;11(10):731-4.
22. Zheng L, Weng M, He J, Yang X, Jiang G, Tong Q. Expression of resistin-like molecule beta in gastric cancer: its relationship with clinicopathological parameters and prognosis. Virchows Arch. 2010;456(1):53-63.
23. Correa P. A human model of gastric carcinogenesis. Cancer Res. 1988;48(13):3554-60.
24. Akyurek N, Akyol G, Dursun A, Yamac D, Gunel N. Expression of MUC1 and MUC2 mucins in gastric carcinomas: their relationship with clinicopathologic parameters and prognosis. Pathol Res Pract. 2002;198(10):665-74.
25. Edmondson DG, Olson EN. A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. Genes Dev. 1989;3(5):628-40.
26. Lassar AB, Buskin JN, Lockshon D, Davis RL, Apone S, Hauschka SD, et al. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell. 1989;58(5):823-31.
27. Ludwig SR, Habera LF, Dellaporta SL, Wessler SR. Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region. Proc Natl Acad Sci USA. 1989;86(18):7092-6.
28. Murre C, McCaw PS, Vaessin H, Caudy M, Jan LY, Jan YN, et al. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell. 1989;58(3):537-44.
29. Murre C, McCaw PS, Baltimore D. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell. 1989;56(5):777-83.
30. Bae Y, Kim H, Namgoong H, Baek M, Lee J, Hwang D, et al. Characterization of microsatellite markers adjacent to AP-4 on chromosome 16p13.3. Mol Cell Probes. 2001;15(5):313-5.
31. Buechler S. Low expression of a few genes indicates good prognosis in estrogen receptor positive breast cancer. BMC Cancer. 2009;9:243.
32. Xi YG, Ding KY, Su XL, Chen DF, You WC, Shen Y, et al. p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions. Carcinogenesis. 2004;25(11):2201-6.
33. Seo YH, Joo YE, Choi SK, Rew JS, Park CS, Kim SJ. Prognostic significance of p21 and p53 expression in gastric cancer. Korean J Intern Med. 2003;18(2):98-103.
34. Hajdu J, Kozma L, Kiss I, Szentkereszty Z, Szakall S, Ember I. Is the presence of distant metastasis associated with c-myc amplification in gastric cancer? Acta Chir Hung. 1997;36(1-4):119-21.
35. Onoda N, Maeda K, Chung YS, Yano Y, Matsui-Yuasa I, Otani S, et al. Overexpression of c-myc messenger RNA in primary and metastatic lesions of carcinoma of the stomach. J Am Coll Surg. 1996;182(1):55-9.
36. Kouraklis G, Katsoulis IE, Theocharis S, Tsourouflis G, Xipolitas N, Glinavou A, et al. Does the expression of cyclin E, pRb, and p21 correlate with prognosis in gastric adenocarcinoma? Dig Dis Sci. 2009;54(5):1015-20.
37. Han S, Kim HY, Park K, Cho HJ, Lee MS, Kim HJ, et al. c-Myc expression is related with cell proliferation and associated with poor clinical outcome in human gastric cancer. J Korean Med Sci. 1999;14(5):526-30.