Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor

Basic Research in Cardiology

Volumn 112, Issue 2, 2017, Pages

  Jovancevic, Nikolina ^a   Dendorfer, A ^b,f   Matzkies, M ^c   Kovarova, M ^e   Heckmann, J C ^a   Osterloh, M ^a   Boehm, M ^a   Weber, L ^a   Nguemo, F ^c   Semmler, J ^c   Hescheler, J ^c   Milting, H ^d   Schleicher, E ^e   Gelis, L ^a   Hatt, H ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

^e UNIVERSITY OF TÜBINGEN   (Germany)

^f DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Calcium transients; Medium chain fatty acids; Negative chronotropic effect; Negative inotropic effect; Olfactory receptor

Indexed keywords

2 ETHYLHEXANOIC ACID; DECANOIC ACID; FATTY ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; LAURIC ACID; MEDIUM CHAIN FATTY ACID; MYRISTIC ACID; NONANOIC ACID; OLEIC ACID; PALMITIC ACID; PENTADECANOIC ACID; STEARIC ACID; TRIDECANOIC ACID; UNCLASSIFIED DRUG; UNDECANOIC ACID; G PROTEIN COUPLED RECEPTOR; OR51E1 PROTEIN, HUMAN; TUMOR PROTEIN;

ADULT; ARTICLE; CARDIAC MUSCLE CELL; CHRONOTROPISM; CONTROLLED STUDY; EMBRYO; FATTY ACID BLOOD LEVEL; FETUS; HEART FUNCTION; HEART MUSCLE CONTRACTILE FORCE; HEART TRABECULAR MUSCLE; HUMAN; HUMAN CELL; HUMAN TISSUE; INOTROPISM; LUCIFERASE ASSAY; LUCIFERASE REPORTER GENE ACTIVATION ASSAY; NEXT GENERATION SEQUENCING; ODORANT RECEPTOR OR51E1; OLFACTORY RECEPTOR; SIGNAL TRANSDUCTION; CARDIAC MUSCLE; CELL CULTURE; GENE SILENCING; HIGH THROUGHPUT SEQUENCING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELLS, CULTURED; FATTY ACIDS; GENE KNOCKDOWN TECHNIQUES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MYOCARDIUM; MYOCYTES, CARDIAC; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED;

EID: 85010685768     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-017-0600-y     Document Type: Article

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