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Volumn 288, Issue 15, 2013, Pages 10684-10691

Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTORS; INTRAVENOUS INJECTIONS; MEDIUM-CHAIN FATTY ACIDS; PATHOPHYSIOLOGICAL; PHOSPHOINOSITIDES; POLYMORPHONUCLEAR LEUKOCYTES; POTENTIAL LIGAND; PROINFLAMMATORY CYTOKINES;

EID: 84876280393     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.420042     Document Type: Article
Times cited : (166)

References (41)
  • 1
    • 69549111756 scopus 로고    scopus 로고
    • Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients
    • Wellendorph, P., Johansen, L. D., and Bräuner-Osborne, H. (2009) Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients. Mol. Pharmacol. 76, 453-465
    • (2009) Mol. Pharmacol , vol.76 , pp. 453-465
    • Wellendorph, P.1    Johansen, L.D.2    Bräuner-Osborne, H.3
  • 2
    • 84864541097 scopus 로고    scopus 로고
    • G protein-coupled receptors for energy metabolites as new therapeutic targets
    • Blad, C. C., Tang, C., and Offermanns, S. (2012) G protein-coupled receptors for energy metabolites as new therapeutic targets. Nat. Rev. Drug Discov. 11, 603-619
    • (2012) Nat. Rev. Drug Discov , vol.11 , pp. 603-619
    • Blad, C.C.1    Tang, C.2    Offermanns, S.3
  • 7
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin- sensitizing effects
    • Oh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., and Olefsky, J. M. (2010) GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin- sensitizing effects. Cell 142, 687-698
    • (2010) Cell , vol.142 , pp. 687-698
    • Oh, D.Y.1    Talukdar, S.2    Bae, E.J.3    Imamura, T.4    Morinaga, H.5    Fan, W.6    Li, P.7    Lu, W.J.8    Watkins, S.M.9    Olefsky, J.M.10
  • 11
    • 50449087891 scopus 로고    scopus 로고
    • Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids
    • Ge, H., Li, X., Weiszmann, J., Wang, P., Baribault, H., Chen, J. L., Tian, H., and Li, Y. (2008) Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 149, 4519-4526
    • (2008) Endocrinology , vol.149 , pp. 4519-4526
    • Ge, H.1    Li, X.2    Weiszmann, J.3    Wang, P.4    Baribault, H.5    Chen, J.L.6    Tian, H.7    Li, Y.8
  • 14
    • 0035970294 scopus 로고    scopus 로고
    • An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors
    • Wittenberger, T., Schaller, H. C., and Hellebrand, S. (2001) An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. J. Mol. Biol. 307, 799-813
    • (2001) J. Mol. Biol , vol.307 , pp. 799-813
    • Wittenberger, T.1    Schaller, H.C.2    Hellebrand, S.3
  • 15
    • 0034978118 scopus 로고    scopus 로고
    • Cloning and expression analysis of a novel G-protein-coupled receptor selectively expressed on granulocytes
    • Yousefi, S., Cooper, P. R., Potter, S. L., Mueck, B., and Jarai, G. (2001) Cloning and expression analysis of a novel G-protein-coupled receptor selectively expressed on granulocytes. J. Leukoc. Biol. 69, 1045-1052
    • (2001) J. Leukoc. Biol , vol.69 , pp. 1045-1052
    • Yousefi, S.1    Cooper, P.R.2    Potter, S.L.3    Mueck, B.4    Jarai, G.5
  • 16
    • 33845954973 scopus 로고    scopus 로고
    • Mediumchain fatty acids as ligands for orphanGprotein-coupled receptor GPR84
    • Wang, J., Wu, X., Simonavicius, N., Tian, H., and Ling, L. (2006) Mediumchain fatty acids as ligands for orphanGprotein-coupled receptor GPR84. J. Biol. Chem. 281, 34457-34464
    • (2006) J. Biol. Chem , vol.281 , pp. 34457-34464
    • Wang, J.1    Wu, X.2    Simonavicius, N.3    Tian, H.4    Ling, L.5
  • 17
    • 25444438205 scopus 로고    scopus 로고
    • The G-protein coupled receptor, GPR84 regulates IL-4 production by T lymphocytes in response to CD3 crosslinking
    • Venkataraman, C., and Kuo, F. (2005) The G-protein coupled receptor, GPR84 regulates IL-4 production by T lymphocytes in response to CD3 crosslinking. Immunol. Lett. 101, 144-153
    • (2005) Immunol. Lett , vol.101 , pp. 144-153
    • Venkataraman, C.1    Kuo, F.2
  • 19
    • 84862314149 scopus 로고    scopus 로고
    • Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers
    • Guo, L., Zhang, X., Zhou, D., Okunade, A. L., and Su, X. (2012) Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers. J. Lipid Res. 53, 1327-1335
    • (2012) J. Lipid Res , vol.53 , pp. 1327-1335
    • Guo, L.1    Zhang, X.2    Zhou, D.3    Okunade, A.L.4    Su, X.5
  • 20
    • 0031914110 scopus 로고    scopus 로고
    • Simultaneous analysis of plasma free fatty acids and their 3-hydroxy analogs in fatty acidβ-oxidation disorders
    • Costa, C. G., Dorland, L., Holwerda, U., de Almeida, I. T., Poll-The, B. T., Jakobs, C., and Duran, M. (1998) Simultaneous analysis of plasma free fatty acids and their 3-hydroxy analogs in fatty acidβ-oxidation disorders. Clin. Chem. 44, 463-471
    • (1998) Clin. Chem , vol.44 , pp. 463-471
    • Costa, C.G.1    Dorland, L.2    Holwerda, U.3    De Almeida, I.T.4    Poll-The, B.T.5    Jakobs, C.6    Duran, M.7
  • 21
    • 80255124809 scopus 로고    scopus 로고
    • Clinical applications of 3-hydroxy fatty acid analysis by gas chromatography-mass spectrometry
    • Jones, P. M., and Bennett, M. J. (2011) Clinical applications of 3-hydroxy fatty acid analysis by gas chromatography-mass spectrometry. Biochim. Biophys. Acta 1811, 657-662
    • (2011) Biochim. Biophys. Acta , vol.1811 , pp. 657-662
    • Jones, P.M.1    Bennett, M.J.2
  • 22
    • 0029087177 scopus 로고
    • Lipopolysaccharide determination by reversed-phase high-performance liquid chromatography after fluorescence labeling
    • Parlesak, A., and Bode, C. (1995) Lipopolysaccharide determination by reversed-phase high-performance liquid chromatography after fluorescence labeling. J. Chromatogr. A 711, 277-288
    • (1995) J. Chromatogr. A , vol.711 , pp. 277-288
    • Parlesak, A.1    Bode, C.2
  • 25
    • 69249083201 scopus 로고    scopus 로고
    • Deorphanization of GPR109B as a receptor for the β-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis
    • Ahmed, K., Tunaru, S., Langhans, C. D., Hanson, J., Michalski, C. W., Kölker, S., Jones, P. M., Okun, J. G., and Offermanns, S. (2009) Deorphanization of GPR109B as a receptor for the β-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis. J. Biol. Chem. 284, 21928-21933
    • (2009) J. Biol. Chem , vol.284 , pp. 21928-21933
    • Ahmed, K.1    Tunaru, S.2    Langhans, C.D.3    Hanson, J.4    Michalski, C.W.5    Kölker, S.6    Jones, P.M.7    Okun, J.G.8    Offermanns, S.9
  • 26
    • 84986532411 scopus 로고
    • Synthesis of a proposed isomer of F420 having α-glutamyl bonding
    • Kimachi, T., Tanaka, K., and Yoneda, F. (1991) Synthesis of a proposed isomer of F420 having α-glutamyl bonding. J. Heterocyc. Chem. 28, 439-443
    • (1991) J. Heterocyc. Chem , vol.28 , pp. 439-443
    • Kimachi, T.1    Tanaka, K.2    Yoneda, F.3
  • 29
    • 2342435824 scopus 로고    scopus 로고
    • Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1
    • Lee, J. Y., Zhao, L., Youn, H. S., Weatherill, A. R., Tapping, R., Feng, L., Lee, W. H., Fitzgerald, K. A., and Hwang, D. H. (2004) Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. J. Biol. Chem. 279, 16971-16979
    • (2004) J. Biol. Chem , vol.279 , pp. 16971-16979
    • Lee, J.Y.1    Zhao, L.2    Youn, H.S.3    Weatherill, A.R.4    Tapping, R.5    Feng, L.6    Lee, W.H.7    Fitzgerald, K.A.8    Hwang, D.H.9
  • 31
    • 34249062904 scopus 로고    scopus 로고
    • G protein-coupled receptor 84, a microglia-associated protein expressed in neuroinflammatory conditions
    • Bouchard, C., Pagé, J., Bédard, A., Tremblay, P., and Vallières, L. (2007) G protein-coupled receptor 84, a microglia-associated protein expressed in neuroinflammatory conditions. Glia 55, 790-800
    • (2007) Glia , vol.55 , pp. 790-800
    • Bouchard, C.1    Pagé, J.2    Bédard, A.3    Tremblay, P.4    Vallières, L.5
  • 32
    • 0029037213 scopus 로고
    • Recombinant production and biological properties of rat cytokine-induced neutrophil chemoattractants, GRO/ CINC-2α, CINC-2β, and CINC-3
    • Shibata, F., Konishi, K., Kato, H., Komorita, N., al-Mokdad, M., Fujioka, M., and Nakagawa, H. (1995) Recombinant production and biological properties of rat cytokine-induced neutrophil chemoattractants, GRO/ CINC-2α, CINC-2β, and CINC-3. Eur. J. Biochem. 231, 306-311
    • (1995) Eur. J. Biochem , vol.231 , pp. 306-311
    • Shibata, F.1    Konishi, K.2    Kato, H.3    Komorita, N.4    Al-Mokdad, M.5    Fujioka, M.6    Nakagawa, H.7
  • 33
    • 0029949923 scopus 로고    scopus 로고
    • Cytokine-induced neutrophil chemoattractant (CINC)-2α, a novel member of rat GRO/CINCs, is a predominant chemokine produced by lipopolysaccharide- stimulated rat macrophages in culture
    • Nakagawa, H., Shiota, S., Takano, K., Shibata, F., and Kato, H. (1996) Cytokine-induced neutrophil chemoattractant (CINC)-2α, a novel member of rat GRO/CINCs, is a predominant chemokine produced by lipopolysaccharide- stimulated rat macrophages in culture. Biochem. Biophys. Res. Commun. 220, 945-948
    • (1996) Biochem. Biophys. Res. Commun , vol.220 , pp. 945-948
    • Nakagawa, H.1    Shiota, S.2    Takano, K.3    Shibata, F.4    Kato, H.5
  • 34
    • 33749522032 scopus 로고    scopus 로고
    • The evaluation of the role of β-hydroxy fatty acids on chronic inflammation and insulin resistance
    • Soydan, A. S., Dokmetas, H. S., Cetin, M., Koyuncu, A., Kaptanoglu, E., and Elden, H. (2006) The evaluation of the role of β-hydroxy fatty acids on chronic inflammation and insulin resistance. Mediators Inflamm. 2006, 64980
    • (2006) Mediators Inflamm , vol.2006 , pp. 64980
    • Soydan, A.S.1    Dokmetas, H.S.2    Cetin, M.3    Koyuncu, A.4    Kaptanoglu, E.5    Elden, H.6
  • 35
    • 81755171447 scopus 로고    scopus 로고
    • Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes
    • Yang, X., Zhang, X., Heckmann, B. L., Lu, X., and Liu, J. (2011) Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes. J. Biol. Chem. 286, 40477-40485
    • (2011) J. Biol. Chem , vol.286 , pp. 40477-40485
    • Yang, X.1    Zhang, X.2    Heckmann, B.L.3    Lu, X.4    Liu, J.5
  • 36
    • 80052021813 scopus 로고    scopus 로고
    • Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases
    • Talukdar, S., Olefsky, J. M., and Osborn, O. (2011) Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases. Trends Pharmacol. Sci. 32, 543-550
    • (2011) Trends Pharmacol. Sci , vol.32 , pp. 543-550
    • Talukdar, S.1    Olefsky, J.M.2    Osborn, O.3
  • 37
    • 79959263075 scopus 로고    scopus 로고
    • The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity
    • Oh, D. Y., and Lagakos, W. S. (2011) The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity. Curr. Opin. Clin. Nutr. Metab. Care 14, 322-327
    • (2011) Curr. Opin. Clin. Nutr. Metab. Care , vol.14 , pp. 322-327
    • Oh, D.Y.1    Lagakos, W.S.2
  • 38
    • 79955769365 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B
    • Offermanns, S., Colletti, S. L., Lovenberg, T. W., Semple, G., Wise, A., and IJzerman, A. P. (2011) International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B). Pharmacol. Rev. 63, 269-290
    • (2011) Pharmacol. Rev , vol.63 , pp. 269-290
    • Offermanns, S.1    Colletti, S.L.2    Lovenberg, T.W.3    Semple, G.4    Wise, A.5    Ijzerman, A.P.6
  • 39
    • 84864244872 scopus 로고    scopus 로고
    • Metabolic syndrome, insulin resistance, and roles of inflammation - Mechanisms and therapeutic targets
    • Romeo, G. R., Lee, J., and Shoelson, S. E. (2012) Metabolic syndrome, insulin resistance, and roles of inflammation - mechanisms and therapeutic targets. Arterioscler. Thromb. Vasc. Biol. 32, 1771-1776
    • (2012) Arterioscler. Thromb. Vasc. Biol , vol.32 , pp. 1771-1776
    • Romeo, G.R.1    Lee, J.2    Shoelson, S.E.3
  • 40
    • 53149119231 scopus 로고    scopus 로고
    • Neutrophils transiently infiltrate intra-abdominal fat early in the course of highfat feeding
    • Elgazar-Carmon, V., Rudich, A., Hadad, N., and Levy, R. (2008) Neutrophils transiently infiltrate intra-abdominal fat early in the course of highfat feeding. J. Lipid Res. 49, 1894-1903
    • (2008) J. Lipid Res , vol.49 , pp. 1894-1903
    • Elgazar-Carmon, V.1    Rudich, A.2    Hadad, N.3    Levy, R.4
  • 41
    • 84857051975 scopus 로고    scopus 로고
    • Inflammatory changes in adipose tissue enhance expression of GPR84, a mediumchain fatty acid receptor: TNFα enhances GPR84 expression in adipocytes
    • Nagasaki, H., Kondo, T., Fuchigami, M., Hashimoto, H., Sugimura, Y., Ozaki, N., Arima, H., Ota, A., Oiso, Y., and Hamada, Y. (2012) Inflammatory changes in adipose tissue enhance expression of GPR84, a mediumchain fatty acid receptor: TNFα enhances GPR84 expression in adipocytes. FEBS Lett. 586, 368-372
    • (2012) FEBS Lett , vol.586 , pp. 368-372
    • Nagasaki, H.1    Kondo, T.2    Fuchigami, M.3    Hashimoto, H.4    Sugimura, Y.5    Ozaki, N.6    Arima, H.7    Ota, A.8    Oiso, Y.9    Hamada, Y.10


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