Olfactory receptor responding to gut microbiotaderived signals plays a role in renin secretion and blood pressure regulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 11, 2013, Pages 4410-4415

  Pluznick, Jennifer L ^a   Protzko, Ryan J ^a   Gevorgyan, Haykanush ^b   Peterlin, Zita ^c   Sipos, Arnold ^b   Han, Jinah ^d   Brunet, Isabelle ^e   Wan, La Xiang ^d   Rey, Federico ^f   Wang, Tong ^d   Firestein, Stuart J ^c   Yanagisawa, Masashi ^g,h   Gordon, Jeffrey I ^f   Eichmann, Anne ^d   Peti Peterdi, Janos ^b   Caplan, Michael J ^d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e l'alimentation et l'Environnement   (France)

^f WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

GPCR; MOL2.3; MOR18 2; OR51E2

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 41; OLFACTORY RECEPTOR 78; PROPIONIC ACID; RENIN; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BIOMASS; BLOOD PRESSURE REGULATION; EX VIVO STUDY; HYPOTENSION; INTESTINE FLORA; MOUSE; NONHUMAN; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RENIN RELEASE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR RESISTANCE; VASODILATATION;

ANIMALS; BIOMASS; BLOOD PRESSURE; GENE EXPRESSION REGULATION; HYPERTENSION; INTESTINES; KIDNEY; METAGENOME; MICE; MICE, KNOCKOUT; PROPIONATES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, ODORANT; RENIN; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84875047650     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1215927110     Document Type: Article

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