Functional evolution of mammalian odorant receptors

PLoS Genetics

Volumn 8, Issue 7, 2012, Pages

  Adipietro, Kaylin A ^a   Mainland, Joel D ^a,c   Matsunami, Hiroaki ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MONELL CHEMICAL SENSES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLITUDE MODULATION; ARTICLE; CELL SURFACE; CHIMPANZEE; CONTROLLED STUDY; GENETIC DISTANCE; GENOME ANALYSIS; HUMAN; IN VITRO STUDY; MACACA; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; OLFACTORY RECEPTOR; ORTHOLOGY; PREDICTION; PRESSURE MEASUREMENT; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; SPECIES DIFFERENCE;

ANIMALS; EVOLUTION, MOLECULAR; HUMANS; LIGANDS; MACACA MULATTA; MICE; PAN TROGLODYTES; PHYLOGENY; RATS; RECEPTORS, ODORANT; SELECTION, GENETIC; SENSITIVITY AND SPECIFICITY; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

MACACA MULATTA; MAMMALIA; PAN; PRIMATES; RATTUS; RODENTIA;

EID: 84864564596     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002821     Document Type: Article

References (63)

1. Mombaerts P, (2004) Genes and ligands for odorant, vomeronasal and taste receptors. Nat Rev Neurosci 5: 263-278.
2. Keller A, Vosshall LB, (2008) Better smelling through genetics: mammalian odor perception. Curr Opin Neurobiol 18: 364-369.
3. Hayden S, Bekaert M, Crider TA, Mariani S, Murphy WJ, et al. (2010) Ecological adaptation determines functional mammalian olfactory subgenomes. Genome Res 20: 1-9.
4. Koonin EV, (2005) Orthologs, paralogs, and evolutionary genomics. Annu Rev Genet 39: 309-338.
5. Studer RA, Robinson-Rechavi M, (2009) How confident can we be that orthologs are similar, but paralogs differ? Trends Genet 25: 210-216.
6. Nehrt NL, Clark WT, Radivojac P, Hahn MW, (2011) Testing the ortholog conjecture with comparative functional genomic data from mammals. PLoS Comput Biol 7: e1002073 doi:10.1371/journal.pcbi.1002073.
7. Gharib WH, Robinson-Rechavi M, (2011) When orthologs diverge between human and mouse. Brief Bioinform.
8. Gilad Y, Man O, Paabo S, Lancet D, (2003) Human specific loss of olfactory receptor genes. Proc Natl Acad Sci U S A 100: 3324-3327.
9. Man O, Willhite DC, Crasto CJ, Shepherd GM, Gilad Y, (2007) A framework for exploring functional variability in olfactory receptor genes. PLoS ONE 2: e682 doi:10.1371/journal.pone.0000682.
10. Gilad Y, Man O, Glusman G, (2005) A comparison of the human and chimpanzee olfactory receptor gene repertoires. Genome Res 15: 224-230.
11. Glusman G, Yanai I, Rubin I, Lancet D, (2001) The complete human olfactory subgenome. Genome Res 11: 685-702.
12. Matsui A, Go Y, Niimura Y, (2010) Degeneration of olfactory receptor gene repertories in primates: no direct link to full trichromatic vision. Mol Biol Evol 27: 1192-1200.
13. Go Y, Niimura Y, (2008) Similar Numbers but Different Repertoires of Olfactory Receptor Genes in Humans and Chimpanzees. Molecular Biology and Evolution 25: 1897-1907.
14. Niimura Y, Nei M, (2007) Extensive gains and losses of olfactory receptor genes in Mammalian evolution. PLoS ONE 2: e708 doi:10.1371/journal.pone.0000708.
15. Kambere MB, Lane RP, (2007) Co-regulation of a large and rapidly evolving repertoire of odorant receptor genes. BMC Neurosci 8 (Suppl 3): S2.
16. Godfrey PA, Malnic B, Buck LB, (2004) The mouse olfactory receptor gene family. Proc Natl Acad Sci USA 101: 2156-2161.
17. Man O, Gilad Y, Lancet D, (2004) Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons. Protein Sci 13: 240-254.
18. Zhang X, Firestein S, (2002) The olfactory receptor gene superfamily of the mouse. Nat Neurosci 5: 124-133.
19. Malnic B, Hirono J, Sato T, Buck LB, (1999) Combinatorial receptor codes for odors. Cell 96: 713-723.
20. Glusman G, Bahar A, Sharon D, Pilpel Y, White J, et al. (2000) The olfactory receptor gene superfamily: data mining, classification, and nomenclature. Mamm Genome 11: 1016-1023.
21. Schmiedeberg K, Shirokova E, Weber HP, Schilling B, Meyerhof W, et al. (2007) Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2. J Struct Biol 159: 400-412.
22. Krautwurst D, Yau KW, Reed RR, (1998) Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 95: 917-926.
23. Zhuang H, Chien MS, Matsunami H, (2009) Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates. Proc Natl Acad Sci U S A 106: 21247-21251.
24. Li YR, Matsunami H, (2011) Activation state of the m3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling. Sci Signal 4: ra1.
25. Zhuang H, Matsunami H, (2007) Synergism of accessory factors in functional expression of mammalian odorant receptors. J Biol Chem 282: 15284-15293.
26. Zhuang H, Matsunami H, (2008) Evaluating cell-surface expression and measuring activation of mammalian odorant receptors in heterologous cells. Nat Protoc 3: 1402-1413.
27. Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD, (2009) Odor coding by a Mammalian receptor repertoire. Sci Signal 2: ra9.
28. Grus WE, Zhang J, (2008) Distinct evolutionary patterns between chemoreceptors of 2 vertebrate olfactory systems and the differential tuning hypothesis. Mol Biol Evol 25: 1593-1601.
29. Grantham R, (1974) Amino acid difference formula to help explain protein evolution. Science 185: 862-864.
30. Jukes TH, Cantor CR, (1969) Evolution of protein molecules; In: HN M, editors. New York Academic Press.
31. Liman E, Innan H, (2003) Relaxed selective pressure on an essential component of pheromone transduction in primate evolution. Proc Natl Acad Sci USA 100: 3328.
32. Nei M, Niimura Y, Nozawa M, (2008) The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity. Nat Rev Genet pp. 951-963.
33. Haddad R, Khan R, Takahashi YK, Mori K, Harel D, et al. (2008) A metric for odorant comparison. Nat Methods 5: 425-429.
34. Saito H, Kubota M, Roberts RW, Chi Q, Matsunami H, (2004) RTP family members induce functional expression of mammalian odorant receptors. Cell 119: 679-691.
35. Glusman G, Bahar A, Sharon D, Pilpel Y, (2000) The olfactory receptor gene superfamily: data mining, classification, and nomenclature. Mammalian genome.
36. Dey S, Matsunami H, (2011) Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors. Proc Natl Acad Sci U S A 108: 16651-16656.
37. Dey S, Zhan S, Matsunami H, (2011) Assaying surface expression of chemosensory receptors in heterologous cells. J Vis Exp.
38. Gilad Y, Przeworski M, Lancet D, (2004) Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. PLoS Biol 2: e5 doi:10.1371/journal.pbio.0020005.
39. Niimura Y, Nei M, (2005) Evolutionary changes of the number of olfactory receptor genes in the human and mouse lineages. Gene 346: 23-28.
40. Zozulya S, Echeverri F, Nguyen T, (2001) The human olfactory receptor repertoire. Genome Biology.
41. Bremner EA, Mainland JD, Khan RM, Sobel N, (2003) The prevalence of androstenone anosmia. Chem Senses 28: 423-432.
42. Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H, (2007) Genetic variation in a human odorant receptor alters odour perception. Nature 449: 468-472.
43. Wyart C, Webster WW, Chen JH, Wilson SR, McClary A, et al. (2007) Smelling a single component of male sweat alters levels of cortisol in women. J Neurosci 27: 1261-1265.
44. Jacob S, Kinnunen LH, Metz J, Cooper M, McClintock MK, (2001) Sustained human chemosignal unconsciously alters brain function. Neuroreport 12: 2391-2394.
45. Enard W, Gehre S, Hammerschmidt K, Holter SM, Blass T, et al. (2009) A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell 137: 961-971.
46. Fujita E, Tanabe Y, Shiota A, Ueda M, Suwa K, et al. (2008) Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells. Proc Natl Acad Sci U S A 105: 3117-3122.
47. Teramitsu I, Kudo LC, London SE, Geschwind DH, White SA, (2004) Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction. J Neurosci 24: 3152-3163.
48. Yokoyama S, Tada T, Zhang H, Britt L, (2008) Elucidation of phenotypic adaptations: Molecular analyses of dim-light vision proteins in vertebrates. Proc Natl Acad Sci U S A 105: 13480-13485.
49. Bridgham JT, Carroll SM, Thornton JW, (2006) Evolution of hormone-receptor complexity by molecular exploitation. Science 312: 97-101.
50. Thornton JW, Kelley DB, (1998) Evolution of the androgen receptor: structure-function implications. Bioessays 20: 860-869.
51. Thornton JW, Need E, Crews D, (2003) Resurrecting the ancestral steroid receptor: ancient origin of estrogen signaling. Science 301: 1714-1717.
52. Wooding S, Bufe B, Grassi C, Howard MT, Stone AC, et al. (2006) Independent evolution of bitter-taste sensitivity in humans and chimpanzees. Nature 440: 930-934.
53. Grosmaitre X, Fuss SH, Lee AC, Adipietro KA, Matsunami H, et al. (2009) SR1, a mouse odorant receptor with an unusually broad response profile. J Neurosci 29: 14545-14552.
54. Acampora D, Avantaggiato V, Tuorto F, Barone P, Reichert H, et al. (1998) Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development. Development 125: 1691-1702.
55. Ang SL, Jin O, Rhinn M, Daigle N, Stevenson L, et al. (1996) A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development 122: 243-252.
56. Duboule D, Dolle P, (1989) The Structural and Functional-Organization of the Murine Hox Gene Family Resembles That of Drosophila Homeotic Genes. Embo Journal 8: 1497-1505.
57. Malicki J, Schughart K, Mcginnis W, (1990) Mouse Hox-2.2 Specifies Thoracic Segmental Identity in Drosophila Embryos and Larvae. Cell 63: 961-967.
58. Matsuo I, Kuratani S, Kimura C, Takeda N, Aizawa S, (1995) Mouse Otx2 Functions in the Formation and Patterning of Rostral Head. Genes & Development 9: 2646-2658.
59. McClintock JM, Jozefowicz C, Assimacopoulos S, Grove EA, Louvi A, et al. (2003) Conserved expression of Hoxa1 in neurons at the ventral forebrain/midbrain boundary of vertebrates. Development Genes and Evolution 213: 399-406.
60. Nagao T, Leuzinger S, Acampora D, Simeone A, Finkelstein R, et al. (1998) Developmental rescue of Drosophila cephalic defects by the human Otx genes. Proceedings of the National Academy of Sciences of the United States of America 95: 3737-3742.
61. Westmoreland JJ, McEwen J, Moore BA, Jin YS, Condie BG, (2001) Conserved function of Caenorhabditis elegans UNC-30 and mouse Pitx2 in controlling GABAergic neuron differentiation. Journal of Neuroscience 21: 6810-6819.
62. Carey AF, Wang G, Su CY, Zwiebel LJ, Carlson JR, (2010) Odorant reception in the malaria mosquito Anopheles gambiae. Nature 464: 66-71.
63. Nei M, Gojobori T, (1986) Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide. Molecular Biology and Evolution.