메뉴 건너뛰기




Volumn 18, Issue 4, 2017, Pages 230-244

Building a lineage from single cells: Genetic techniques for cell lineage tracking

Author keywords

[No Author keywords available]

Indexed keywords

RETROVIRUS VECTOR;

EID: 85010220036     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg.2016.159     Document Type: Review
Times cited : (189)

References (137)
  • 1
    • 0017808171 scopus 로고
    • Cell lineages of the embryo of the nematode Caenorhabditis elegans
    • Deppe, U. et al. Cell lineages of the embryo of the nematode Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 75, 376-380 (1978).
    • (1978) Proc. Natl Acad. Sci. USA , vol.75 , pp. 376-380
    • Deppe, U.1
  • 2
    • 0020858899 scopus 로고
    • The embryonic cell lineage of the nematode Caenorhabditis elegans
    • Sulston, J. E., Schierenberg, E., White, J. G. & Thomson, J. N. The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 100, 64-119 (1983).
    • (1983) Dev. Biol. , vol.100 , pp. 64-119
    • Sulston, J.E.1    Schierenberg, E.2    White, J.G.3    Thomson, J.N.4
  • 3
    • 0014104297 scopus 로고
    • Gene control of mammalian pigmentary differentiation. I. Clonal origin of melanocytes
    • Mintz, B. Gene control of mammalian pigmentary differentiation. I. Clonal origin of melanocytes. Proc. Natl Acad. Sci. USA 58, 344-351 (1967).
    • (1967) Proc. Natl Acad. Sci. USA , vol.58 , pp. 344-351
    • Mintz, B.1
  • 4
    • 0017499569 scopus 로고
    • Studies of the developmental potential of 4-and 8-cell stage mouse blastomeres
    • Kelly, S. J. Studies of the developmental potential of 4-and 8-cell stage mouse blastomeres. J. Exp. Zool. 200, 365-376 (1977).
    • (1977) J. Exp. Zool. , vol.200 , pp. 365-376
    • Kelly, S.J.1
  • 5
    • 0015888640 scopus 로고
    • The migration of neural crest cells to the wall of the digestive tract in avian embryo
    • Le Douarin, N. M. & Teillet, M. A. The migration of neural crest cells to the wall of the digestive tract in avian embryo. J. Embryol. Exp. Morphol. 30, 31-48 (1973).
    • (1973) J. Embryol. Exp. Morphol. , vol.30 , pp. 31-48
    • Le Douarin, N.M.1    Teillet, M.A.2
  • 6
    • 0015134989 scopus 로고
    • The location of the pregut endoderm in the chick embryo at the primitive streak stage as determined by radioautographic mapping
    • Rosenquist, G. C. The location of the pregut endoderm in the chick embryo at the primitive streak stage as determined by radioautographic mapping. Dev. Biol. 26, 323-335 (1971).
    • (1971) Dev. Biol. , vol.26 , pp. 323-335
    • Rosenquist, G.C.1
  • 7
    • 0019435844 scopus 로고
    • The foundation of two distinct cell lineages within the mouse morula
    • Johnson, M. H. & Ziomek, C. A. The foundation of two distinct cell lineages within the mouse morula. Cell 24, 71-80 (1981).
    • (1981) Cell , vol.24 , pp. 71-80
    • Johnson, M.H.1    Ziomek, C.A.2
  • 8
    • 0022921031 scopus 로고
    • Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer
    • Lawson, K. A., Meneses, J. J. & Pedersen, R. A. Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer. Dev. Biol. 11 5, 325-339 (1986).
    • (1986) Dev. Biol. , vol.115 , pp. 325-339
    • Lawson, K.A.1    Meneses, J.J.2    Pedersen, R.A.3
  • 9
    • 0022997316 scopus 로고
    • Origin of the inner cell mass in mouse embryos: Cell lineage analysis by microinjection
    • Pedersen, R. A., Wu, K. & Bałakier, H. Origin of the inner cell mass in mouse embryos: cell lineage analysis by microinjection. Dev. Biol. 11 7, 581-595 (1986).
    • (1986) Dev. Biol. , vol.117 , pp. 581-595
    • Pedersen, R.A.1    Wu, K.2    Bałakier, H.3
  • 10
    • 0033176835 scopus 로고    scopus 로고
    • Fate maps old and new
    • Clarke, J. D. & Tickle, C. Fate maps old and new. Nat. Cell Biol. 1, E103-E109 (1999).
    • (1999) Nat. Cell Biol. , vol.1 , pp. E103-E109
    • Clarke, J.D.1    Tickle, C.2
  • 11
    • 77950981309 scopus 로고    scopus 로고
    • Cellular barcoding tool for clonal analysis in the hematopoietic system
    • Gerrits, A. et al. Cellular barcoding tool for clonal analysis in the hematopoietic system. Blood 11 5, 2610-2618 (2010).
    • (2010) Blood , vol.115 , pp. 2610-2618
    • Gerrits, A.1
  • 13
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR-Cas9 for genome engineering
    • Hsu, P. D., Lander, E. S. & Zhang, F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 157, 1262-1278 (2014).
    • (2014) Cell , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 14
    • 79953766940 scopus 로고    scopus 로고
    • Tumour evolution inferred by single-cell sequencing
    • Navin, N. et al. Tumour evolution inferred by single-cell sequencing. Nature 472, 90-94 (2011).
    • (2011) Nature , vol.472 , pp. 90-94
    • Navin, N.1
  • 15
    • 84906238686 scopus 로고    scopus 로고
    • Clonal evolution in breast cancer revealed by single nucleus genome sequencing
    • Wang, Y. et al. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature 512, 155-160 (2014).
    • (2014) Nature , vol.512 , pp. 155-160
    • Wang, Y.1
  • 16
    • 84907737648 scopus 로고    scopus 로고
    • Genome sequencing of normal cells reveals developmental lineages and mutational processes
    • Behjati, S. et al. Genome sequencing of normal cells reveals developmental lineages and mutational processes. Nature 513, 422-425 (2014).
    • (2014) Nature , vol.513 , pp. 422-425
    • Behjati, S.1
  • 17
    • 84945278558 scopus 로고    scopus 로고
    • Somatic mutation in single human neurons tracks developmental and transcriptional history
    • Lodato, M. A. et al. Somatic mutation in single human neurons tracks developmental and transcriptional history. Science 350, 94-98 (2015).
    • (2015) Science , vol.350 , pp. 94-98
    • Lodato, M.A.1
  • 18
    • 0019604166 scopus 로고
    • An autoradiographic analysis of the potency of embryonic ectoderm in the 8th day postimplantation mouse embryo
    • Beddington, R. An autoradiographic analysis of the potency of embryonic ectoderm in the 8th day postimplantation mouse embryo. Development 64, 87-104 (1981).
    • (1981) Development , vol.64 , pp. 87-104
    • Beddington, R.1
  • 19
    • 0024430539 scopus 로고
    • A vital dye analysis of the timing and pathways of avian trunk neural crest cell migration
    • Serbedzija, G. N., Bronner-Fraser, M. & Fraser, S. E. A vital dye analysis of the timing and pathways of avian trunk neural crest cell migration. Development 106, 809-816 (1989).
    • (1989) Development , vol.106 , pp. 809-816
    • Serbedzija, G.N.1    Bronner-Fraser, M.2    Fraser, S.E.3
  • 20
    • 0023182049 scopus 로고
    • A common progenitor for neurons and glia persists in rat retina late in development
    • Turner, D. L. & Cepko, C. L. A common progenitor for neurons and glia persists in rat retina late in development. Nature 328, 131-136 (1987).
    • (1987) Nature , vol.328 , pp. 131-136
    • Turner, D.L.1    Cepko, C.L.2
  • 21
    • 0025761140 scopus 로고
    • Lineage of neurons and glia in chick dorsal root ganglia: Analysis in vivo with a recombinant retrovirus
    • Frank, E. & Sanes, J. R. Lineage of neurons and glia in chick dorsal root ganglia: analysis in vivo with a recombinant retrovirus. Development 111, 895-908 (1991).
    • (1991) Development , vol.111 , pp. 895-908
    • Frank, E.1    Sanes, J.R.2
  • 22
    • 80055075492 scopus 로고    scopus 로고
    • Clonal production and organization of inhibitory interneurons in the neocortex
    • Brown, K. N. et al. Clonal production and organization of inhibitory interneurons in the neocortex. Science 334, 480-486 (2011).
    • (2011) Science , vol.334 , pp. 480-486
    • Brown, K.N.1
  • 23
    • 0035825670 scopus 로고    scopus 로고
    • Neurons derived from radial glial cells establish radial units in neocortex
    • Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S. & Kriegstein, A. R. Neurons derived from radial glial cells establish radial units in neocortex. Nature 409, 714-720 (2001).
    • (2001) Nature , vol.409 , pp. 714-720
    • Noctor, S.C.1    Flint, A.C.2    Weissman, T.A.3    Dammerman, R.S.4    Kriegstein, A.R.5
  • 24
    • 1642458489 scopus 로고    scopus 로고
    • Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
    • Noctor, S. C., Martinez-Cerdeño, V., Ivic, L. & Kriegstein, A. R. Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases. Nat. Neurosci. 7, 136-144 (2004).
    • (2004) Nat. Neurosci. , vol.7 , pp. 136-144
    • Noctor, S.C.1    Martinez-Cerdeño, V.2    Ivic, L.3    Kriegstein, A.R.4
  • 25
    • 84893644317 scopus 로고    scopus 로고
    • Diverse behaviors of outer radial glia in developing ferret and human cortex
    • Gertz, C. C., Lui, J. H., LaMonica, B. E., Wang, X. & Kriegstein, A. R. Diverse behaviors of outer radial glia in developing ferret and human cortex. J. Neurosci. 34, 2559-2570 (2014).
    • (2014) J. Neurosci. , vol.34 , pp. 2559-2570
    • Gertz, C.C.1    Lui, J.H.2    LaMonica, B.E.3    Wang, X.4    Kriegstein, A.R.5
  • 26
    • 84885728828 scopus 로고    scopus 로고
    • Precursor diversity and complexity of lineage relationships in the outer subventricular zone of the primate
    • Betizeau, M. et al. Precursor diversity and complexity of lineage relationships in the outer subventricular zone of the primate. Neuron 80, 442-457 (2013).
    • (2013) Neuron , vol.80 , pp. 442-457
    • Betizeau, M.1
  • 27
    • 0023773199 scopus 로고
    • Clonally related cortical cells show several migration patterns
    • Walsh, C. A. & Cepko, C. L. Clonally related cortical cells show several migration patterns. Science 241, 1342-1345 (1988).
    • (1988) Science , vol.241 , pp. 1342-1345
    • Walsh, C.A.1    Cepko, C.L.2
  • 28
    • 0026510716 scopus 로고
    • Widespread dispersion of neuronal clones across functional regions of the cerebral cortex
    • Walsh, C. A. & Cepko, C. L. Widespread dispersion of neuronal clones across functional regions of the cerebral cortex. Science 255, 434-440 (1992).
    • (1992) Science , vol.255 , pp. 434-440
    • Walsh, C.A.1    Cepko, C.L.2
  • 29
    • 0027417258 scopus 로고
    • Clonal dispersion in proliferative layers of developing cerebral cortex
    • Walsh, C. A. & Cepko, C. L. Clonal dispersion in proliferative layers of developing cerebral cortex. Nature 362, 632-635 (1993).
    • (1993) Nature , vol.362 , pp. 632-635
    • Walsh, C.A.1    Cepko, C.L.2
  • 30
    • 0029149713 scopus 로고
    • Systematic widespread clonal organization in cerebral cortex
    • Reid, C. B., Liang, I. & Walsh, C. Systematic widespread clonal organization in cerebral cortex. Neuron 15, 299-310 (1995).
    • (1995) Neuron , vol.15 , pp. 299-310
    • Reid, C.B.1    Liang, I.2    Walsh, C.3
  • 31
    • 0029051344 scopus 로고
    • Construction and characterization of a highly complex retroviral library for lineage analysis
    • Golden, J. A., Fields-Berry, S. C. & Cepko, C. L. Construction and characterization of a highly complex retroviral library for lineage analysis. Proc. Natl Acad. Sci. USA 92, 5704-5708 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5704-5708
    • Golden, J.A.1    Fields-Berry, S.C.2    Cepko, C.L.3
  • 32
    • 84934984011 scopus 로고    scopus 로고
    • Embryonic origin of postnatal neural stem cells
    • Fuentealba, L. C. et al. Embryonic origin of postnatal neural stem cells. Cell 161, 1644-1655 (2015).
    • (2015) Cell , vol.161 , pp. 1644-1655
    • Fuentealba, L.C.1
  • 33
    • 84940495930 scopus 로고    scopus 로고
    • Clonally related forebrain interneurons disperse broadly across both functional areas and structural boundaries
    • Mayer, C. et al. Clonally related forebrain interneurons disperse broadly across both functional areas and structural boundaries. Neuron 87, 989-998 (2015).
    • (2015) Neuron , vol.87 , pp. 989-998
    • Mayer, C.1
  • 34
    • 84940554016 scopus 로고    scopus 로고
    • Wide dispersion and diversity of clonally related inhibitory interneurons
    • Harwell, C. C. et al. Wide dispersion and diversity of clonally related inhibitory interneurons. Neuron 87, 999-1007 (2015).
    • (2015) Neuron , vol.87 , pp. 999-1007
    • Harwell, C.C.1
  • 35
    • 80054719497 scopus 로고    scopus 로고
    • Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding
    • Lu, R., Neff, N. F., Quake, S. R. & Weissman, I. L. Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat. Biotechnol. 29, 928-933 (2011).
    • (2011) Nat. Biotechnol. , vol.29 , pp. 928-933
    • Lu, R.1    Neff, N.F.2    Quake, S.R.3    Weissman, I.L.4
  • 36
    • 0025272049 scopus 로고
    • Lipofection of cDNAs in the embryonic vertebrate central nervous system
    • Holt, C. E., Garlick, N. & Cornel, E. Lipofection of cDNAs in the embryonic vertebrate central nervous system. Neuron 4, 203-214 (1990).
    • (1990) Neuron , vol.4 , pp. 203-214
    • Holt, C.E.1    Garlick, N.2    Cornel, E.3
  • 37
    • 80755125323 scopus 로고    scopus 로고
    • Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors
    • Emerson, M. M. & Cepko, C. L. Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Dev. Biol. 360, 241-255 (2011).
    • (2011) Dev. Biol. , vol.360 , pp. 241-255
    • Emerson, M.M.1    Cepko, C.L.2
  • 38
    • 0035798089 scopus 로고    scopus 로고
    • Neocortex patterning by the secreted signaling molecule FGF8
    • Fukuchi-Shimogori, T. & Grove, E. A. Neocortex patterning by the secreted signaling molecule FGF8. Science 294, 1071-1074 (2001).
    • (2001) Science , vol.294 , pp. 1071-1074
    • Fukuchi-Shimogori, T.1    Grove, E.A.2
  • 39
    • 69449103616 scopus 로고    scopus 로고
    • New and improved tools for in utero electroporation studies of developing cerebral cortex
    • LoTurco, J., Manent, J.-B. & Sidiqi, F. New and improved tools for in utero electroporation studies of developing cerebral cortex. Cereb. Cortex 19 (Suppl. 1), i120-i125 (2009).
    • (2009) Cereb. Cortex , vol.19 , pp. i120-i125
    • LoTurco, J.1    Manent, J.-B.2    Sidiqi, F.3
  • 40
    • 33750060436 scopus 로고    scopus 로고
    • PiggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells
    • Wu, S., Meir, Y. & Coates, C. J. piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells. Proc. Natl Acad. Sci. USA 103, 15008-15013 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 15008-15013
    • Wu, S.1    Meir, Y.2    Coates, C.J.3
  • 41
    • 70349356638 scopus 로고    scopus 로고
    • Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells
    • VandenDriessche, T., Ivics, Z., Izsvák, Z. & Chuah, M. K. L. Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells. Blood 11 4, 1461-1468 (2009).
    • (2009) Blood , vol.114 , pp. 1461-1468
    • VandenDriessche, T.1    Ivics, Z.2    Izsvák, Z.3    Chuah, M.K.L.4
  • 42
    • 77953220328 scopus 로고    scopus 로고
    • Simultaneous expression of different transgenes in neurons and glia by combining in utero electroporation with the Tol2 transposon-mediated gene transfer system
    • Yoshida, A. et al. Simultaneous expression of different transgenes in neurons and glia by combining in utero electroporation with the Tol2 transposon-mediated gene transfer system. Genes Cells 15, 501-512 (2010).
    • (2010) Genes Cells , vol.15 , pp. 501-512
    • Yoshida, A.1
  • 43
    • 84860371181 scopus 로고    scopus 로고
    • A method for stable transgenesis of radial glia lineage in rat neocortex by piggyBac mediated transposition
    • Chen, F. & LoTurco, J. A method for stable transgenesis of radial glia lineage in rat neocortex by piggyBac mediated transposition. J. Neurosci. Methods 207, 172-180 (2012).
    • (2012) J. Neurosci. Methods , vol.207 , pp. 172-180
    • Chen, F.1    LoTurco, J.2
  • 44
    • 84896274343 scopus 로고    scopus 로고
    • Fate mapping by piggyBac transposase reveals that neocortical GLAST+ progenitors generate more astrocytes than nestin+ progenitors in rat neocortex
    • Siddiqi, F. et al. Fate mapping by piggyBac transposase reveals that neocortical GLAST+ progenitors generate more astrocytes than nestin+ progenitors in rat neocortex. Cereb. Cortex 24, 508-520 (2014).
    • (2014) Cereb. Cortex , vol.24 , pp. 508-520
    • Siddiqi, F.1
  • 45
    • 23744479962 scopus 로고    scopus 로고
    • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
    • Ding, S. et al. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell 122, 473-483 (2005).
    • (2005) Cell , vol.122 , pp. 473-483
    • Ding, S.1
  • 46
    • 33845981514 scopus 로고    scopus 로고
    • PiggyBac transposon-mediated gene transfer in human cells
    • Wilson, M. H., Coates, C. J. & George, A. L. PiggyBac transposon-mediated gene transfer in human cells. Mol. Ther. 15, 139-145 (2007).
    • (2007) Mol. Ther. , vol.15 , pp. 139-145
    • Wilson, M.H.1    Coates, C.J.2    George, A.L.3
  • 47
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen, K. et al. PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770 (2009).
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1
  • 48
    • 0026764280 scopus 로고
    • Tissue-and site-specific DNA recombination in transgenic mice
    • Orban, P. C., Chui, D. & Marth, J. D. Tissue-and site-specific DNA recombination in transgenic mice. Proc. Natl Acad. Sci. USA 89, 6861-6865 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6861-6865
    • Orban, P.C.1    Chui, D.2    Marth, J.D.3
  • 49
    • 0346503889 scopus 로고    scopus 로고
    • Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
    • Branda, C. S. & Dymecki, S. M. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 6, 7-28 (2004).
    • (2004) Dev. Cell , vol.6 , pp. 7-28
    • Branda, C.S.1    Dymecki, S.M.2
  • 50
    • 84963747984 scopus 로고    scopus 로고
    • Ctip1 controls acquisition of sensory area identity and establishment of sensory input fields in the developing neocortex
    • Greig, L. C., Woodworth, M. B., Greppi, C. & Macklis, J. D. Ctip1 controls acquisition of sensory area identity and establishment of sensory input fields in the developing neocortex. Neuron 90, 261-277 (2016).
    • (2016) Neuron , vol.90 , pp. 261-277
    • Greig, L.C.1    Woodworth, M.B.2    Greppi, C.3    MacKlis, J.D.4
  • 51
    • 0041353550 scopus 로고    scopus 로고
    • Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation
    • Awatramani, R., Soriano, P., Rodriguez, C., Mai, J. J. & Dymecki, S. M. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat. Genet. 35, 70-75 (2003).
    • (2003) Nat. Genet. , vol.35 , pp. 70-75
    • Awatramani, R.1    Soriano, P.2    Rodriguez, C.3    Mai, J.J.4    Dymecki, S.M.5
  • 52
    • 33646068370 scopus 로고    scopus 로고
    • Assembly of the brainstem cochlear nuclear complex is revealed by intersectional and subtractive genetic fate maps
    • Farago, A. F., Awatramani, R. B. & Dymecki, S. M. Assembly of the brainstem cochlear nuclear complex is revealed by intersectional and subtractive genetic fate maps. Neuron 50, 205-218 (2006).
    • (2006) Neuron , vol.50 , pp. 205-218
    • Farago, A.F.1    Awatramani, R.B.2    Dymecki, S.M.3
  • 53
    • 65449158038 scopus 로고    scopus 로고
    • A multifunctional reporter mouse line for Cre-and FLP-dependent lineage analysis
    • Yamamoto, M. et al. A multifunctional reporter mouse line for Cre-and FLP-dependent lineage analysis. Genesis 47, 107-114 (2009).
    • (2009) Genesis , vol.47 , pp. 107-114
    • Yamamoto, M.1
  • 54
    • 18844421090 scopus 로고    scopus 로고
    • Mosaic analysis with double markers in mice
    • Zong, H., Espinosa, J. S., Su, H. H., Muzumdar, M. D. & Luo, L. Mosaic analysis with double markers in mice. Cell 121, 479-492 (2005).
    • (2005) Cell , vol.121 , pp. 479-492
    • Zong, H.1    Espinosa, J.S.2    Su, H.H.3    Muzumdar, M.D.4    Luo, L.5
  • 55
    • 79959681732 scopus 로고    scopus 로고
    • In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics
    • Bonaguidi, M. A. et al. In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics. Cell 145, 1142-1155 (2011).
    • (2011) Cell , vol.145 , pp. 1142-1155
    • Bonaguidi, M.A.1
  • 56
    • 78449291189 scopus 로고    scopus 로고
    • Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration
    • Hippenmeyer, S. et al. Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration. Neuron 68, 695-709 (2010).
    • (2010) Neuron , vol.68 , pp. 695-709
    • Hippenmeyer, S.1
  • 57
    • 35948992641 scopus 로고    scopus 로고
    • Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
    • Livet, J. et al. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature 450, 56-62 (2007).
    • (2007) Nature , vol.450 , pp. 56-62
    • Livet, J.1
  • 58
    • 77957223906 scopus 로고    scopus 로고
    • Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
    • Snippert, H. J. et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 143, 134-144 (2010).
    • (2010) Cell , vol.143 , pp. 134-144
    • Snippert, H.J.1
  • 59
    • 79958761641 scopus 로고    scopus 로고
    • Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung
    • Sutherland, K. D. et al. Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell 19, 754-764 (2011).
    • (2011) Cancer Cell , vol.19 , pp. 754-764
    • Sutherland, K.D.1
  • 60
    • 79955016301 scopus 로고    scopus 로고
    • Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells
    • Beier, K. T., Samson, M. E. S., Matsuda, T. & Cepko, C. L. Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Dev. Biol. 353, 309-320 (2011).
    • (2011) Dev. Biol. , vol.353 , pp. 309-320
    • Beier, K.T.1    Samson, M.E.S.2    Matsuda, T.3    Cepko, C.L.4
  • 61
    • 84899013712 scopus 로고    scopus 로고
    • Multiplexing clonality: Combining RGB marking and genetic barcoding
    • Cornils, K. et al. Multiplexing clonality: combining RGB marking and genetic barcoding. Nucleic Acids Res. 42, e56 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. e56
    • Cornils, K.1
  • 62
    • 84893517238 scopus 로고    scopus 로고
    • Multiplex cell and lineage tracking with combinatorial labels
    • Loulier, K. et al. Multiplex cell and lineage tracking with combinatorial labels. Neuron 81, 505-520 (2014).
    • (2014) Neuron , vol.81 , pp. 505-520
    • Loulier, K.1
  • 63
    • 84954562766 scopus 로고    scopus 로고
    • A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
    • Kimmerling, R. J. et al. A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages. Nat. Commun. 7, 10220 (2015).
    • (2015) Nat. Commun. , vol.7 , pp. 10220
    • Kimmerling, R.J.1
  • 64
    • 84974576984 scopus 로고    scopus 로고
    • Whole organism lineage tracing by combinatorial and cumulative genome editing
    • McKenna, A. et al. Whole organism lineage tracing by combinatorial and cumulative genome editing. Science 353, aaf7907 (2016).
    • (2016) Science 353, aaf7907
    • McKenna, A.1
  • 66
    • 85002263454 scopus 로고    scopus 로고
    • Rapidly evolving homing CRISPR barcodes
    • Kalhor, R., Mali, P. & Church, G. M. Rapidly evolving homing CRISPR barcodes. Nat. Methods http://dx.doi.org/10.1038/nmeth.4108 (2016).
    • (2016) Nat. Methods
    • Kalhor, R.1    Mali, P.2    Church, G.M.3
  • 67
    • 85016160400 scopus 로고    scopus 로고
    • Synthetic recording and in situ readout of lineage information in single cells
    • Frieda, K. L. et al. Synthetic recording and in situ readout of lineage information in single cells. Nature http://dx.doi.org/10.1038/nature20777 (2016).
    • (2016) Nature
    • Frieda, K.L.1
  • 69
    • 74849103102 scopus 로고    scopus 로고
    • Phylogenetic analysis of developmental and postnatal mouse cell lineages
    • Salipante, S. J., Kas, A., McMonagle, E. & Horwitz, M. S. Phylogenetic analysis of developmental and postnatal mouse cell lineages. Evol. Dev. 12, 84-94 (2010).
    • (2010) Evol. Dev. , vol.12 , pp. 84-94
    • Salipante, S.J.1    Kas, A.2    McMonagle, E.3    Horwitz, M.S.4
  • 70
    • 84882455458 scopus 로고    scopus 로고
    • Single-cell sequencing-based technologies will revolutionize whole-organism science
    • Shapiro, E., Biezuner, T. & Linnarsson, S. Single-cell sequencing-based technologies will revolutionize whole-organism science. Nat. Rev. Genet. 14, 618-630 (2013).
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 618-630
    • Shapiro, E.1    Biezuner, T.2    Linnarsson, S.3
  • 71
    • 84946226911 scopus 로고    scopus 로고
    • Design and analysis of single-cell sequencing experiments
    • Grün, D. & van Oudenaarden, A. Design and analysis of single-cell sequencing experiments. Cell 163, 799-810 (2015).
    • (2015) Cell , vol.163 , pp. 799-810
    • Grün, D.1    Van Oudenaarden, A.2
  • 72
    • 84958606331 scopus 로고    scopus 로고
    • Single-cell genome sequencing: Current state of the science
    • Gawad, C., Koh, W. & Quake, S. R. Single-cell genome sequencing: current state of the science. Nat. Rev. Genet. 17, 175-188 (2016).
    • (2016) Nat. Rev. Genet. , vol.17 , pp. 175-188
    • Gawad, C.1    Koh, W.2    Quake, S.R.3
  • 73
    • 0035674903 scopus 로고    scopus 로고
    • Biology of mammalian L1 retrotransposons
    • Ostertag, E. M. & Kazazian, H. H. Biology of mammalian L1 retrotransposons. Annu. Rev. Genet. 35, 501-538 (2001).
    • (2001) Annu. Rev. Genet. , vol.35 , pp. 501-538
    • Ostertag, E.M.1    Kazazian, H.H.2
  • 74
    • 20544466648 scopus 로고    scopus 로고
    • Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition
    • Muotri, A. R. et al. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature 435, 903-910 (2005).
    • (2005) Nature , vol.435 , pp. 903-910
    • Muotri, A.R.1
  • 75
    • 84904565384 scopus 로고    scopus 로고
    • Mobile DNA elements in the generation of diversity and complexity in the brain
    • Erwin, J. A., Marchetto, M. C. & Gage, F. H. Mobile DNA elements in the generation of diversity and complexity in the brain. Nat. Rev. Neurosci. 15, 497-506 (2014).
    • (2014) Nat. Rev. Neurosci. , vol.15 , pp. 497-506
    • Erwin, J.A.1    Marchetto, M.C.2    Gage, F.H.3
  • 76
    • 69349096044 scopus 로고    scopus 로고
    • L1 retrotransposition in human neural progenitor cells
    • Coufal, N. G. et al. L1 retrotransposition in human neural progenitor cells. Nature 460, 1127-1131 (2009).
    • (2009) Nature , vol.460 , pp. 1127-1131
    • Coufal, N.G.1
  • 77
    • 81855178276 scopus 로고    scopus 로고
    • Somatic retrotransposition alters the genetic landscape of the human brain
    • Baillie, J. K. et al. Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479, 534-537 (2011).
    • (2011) Nature , vol.479 , pp. 534-537
    • Baillie, J.K.1
  • 78
    • 84868032982 scopus 로고    scopus 로고
    • Single-neuron sequencing analysis of l1 retrotransposition and somatic mutation in the human brain
    • Evrony, G. D. et al. Single-neuron sequencing analysis of l1 retrotransposition and somatic mutation in the human brain. Cell 151, 483-496 (2012).
    • (2012) Cell , vol.151 , pp. 483-496
    • Evrony, G.D.1
  • 79
    • 84927136066 scopus 로고    scopus 로고
    • Ubiquitous L1 mosaicism in hippocampal neurons
    • Upton, K. R. et al. Ubiquitous L1 mosaicism in hippocampal neurons. Cell 161, 228-239 (2015).
    • (2015) Cell , vol.161 , pp. 228-239
    • Upton, K.R.1
  • 80
    • 84961266736 scopus 로고    scopus 로고
    • Resolving rates of mutation in the brain using single-neuron genomics
    • Evrony, G. D., Lee, E., Park, P. J. & Walsh, C. A. Resolving rates of mutation in the brain using single-neuron genomics. eLife 5, e12966 (2016).
    • (2016) ELife , vol.5 , pp. e12966
    • Evrony, G.D.1    Lee, E.2    Park, P.J.3    Walsh, C.A.4
  • 81
    • 84920746893 scopus 로고    scopus 로고
    • Cell lineage analysis in human brain using endogenous retroelements
    • Evrony, G. D. et al. Cell lineage analysis in human brain using endogenous retroelements. Neuron 85, 49-59 (2015).
    • (2015) Neuron , vol.85 , pp. 49-59
    • Evrony, G.D.1
  • 82
    • 84871410004 scopus 로고    scopus 로고
    • Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells
    • Abyzov, A. et al. Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells. Nature 492, 438-442 (2012).
    • (2012) Nature , vol.492 , pp. 438-442
    • Abyzov, A.1
  • 83
    • 84958675616 scopus 로고    scopus 로고
    • Assessment of megabase-scale somatic copy number variation using single-cell sequencing
    • Knouse, K. A., Wu, J. & Amon, A. Assessment of megabase-scale somatic copy number variation using single-cell sequencing. Genome Res. 26, 376-384 (2016).
    • (2016) Genome Res. , vol.26 , pp. 376-384
    • Knouse, K.A.1    Wu, J.2    Amon, A.3
  • 84
    • 84887315590 scopus 로고    scopus 로고
    • Mosaic copy number variation in human neurons
    • McConnell, M. J. et al. Mosaic copy number variation in human neurons. Science 342, 632-637 (2013).
    • (2013) Science , vol.342 , pp. 632-637
    • McConnell, M.J.1
  • 85
    • 84922584195 scopus 로고    scopus 로고
    • Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain
    • Cai, X. et al. Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain. Cell Rep. 8, 1280-1289 (2014).
    • (2014) Cell Rep. , vol.8 , pp. 1280-1289
    • Cai, X.1
  • 86
    • 84929658867 scopus 로고    scopus 로고
    • Optimizing sparse sequencing of single cells for highly multiplex copy number profiling
    • Baslan, T. et al. Optimizing sparse sequencing of single cells for highly multiplex copy number profiling. Genome Res. 25, 714-724 (2015).
    • (2015) Genome Res. , vol.25 , pp. 714-724
    • Baslan, T.1
  • 87
    • 76549128519 scopus 로고    scopus 로고
    • Somatic evolutionary genomics: Mutations during development cause highly variable genetic mosaicism with risk of cancer & neurodegeneration
    • Frank, S. A. Somatic evolutionary genomics: mutations during development cause highly variable genetic mosaicism with risk of cancer & neurodegeneration. Proc. Natl Acad. Sci. USA 107 (Suppl. 1), 1725-1730 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 1725-1730
    • Frank, S.A.1
  • 88
    • 84960805198 scopus 로고    scopus 로고
    • The complete genome sequences, unique mutational spectra, and developmental potency of adult neurons revealed by cloning
    • Hazen, J. L. et al. The complete genome sequences, unique mutational spectra, and developmental potency of adult neurons revealed by cloning. Neuron 89, 1223-1236 (2016).
    • (2016) Neuron , vol.89 , pp. 1223-1236
    • Hazen, J.L.1
  • 89
    • 84964381098 scopus 로고    scopus 로고
    • Monovar: Single-nucleotide variant detection in single cells
    • Zafar, H., Wang, Y., Nakhleh, L., Navin, N. & Chen, K. Monovar: single-nucleotide variant detection in single cells. Nat. Methods 13, 505-507 (2016).
    • (2016) Nat. Methods , vol.13 , pp. 505-507
    • Zafar, H.1    Wang, Y.2    Nakhleh, L.3    Navin, N.4    Chen, K.5
  • 90
    • 3042782819 scopus 로고    scopus 로고
    • Microsatellites: Simple sequences with complex evolution
    • Ellegren, H. Microsatellites: simple sequences with complex evolution. Nat. Rev. Genet. 5, 435-445 (2004).
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 435-445
    • Ellegren, H.1
  • 93
    • 79960940121 scopus 로고    scopus 로고
    • Colon stem cell and crypt dynamics exposed by cell lineage reconstruction
    • Reizel, Y. et al. Colon stem cell and crypt dynamics exposed by cell lineage reconstruction. PLoS Genet. 7, e1002192 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002192
    • Reizel, Y.1
  • 94
    • 84859179139 scopus 로고    scopus 로고
    • Cell lineage analysis of the mammalian female germline
    • Reizel, Y. et al. Cell lineage analysis of the mammalian female germline. PLoS Genet. 8, e1002477 (2012).
    • (2012) PLoS Genet. , vol.8 , pp. e1002477
    • Reizel, Y.1
  • 95
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau, S. N., Bren, G. & Schaid, D. Microsatellite instability in cancer of the proximal colon. Science 260, 816-819 (1993).
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 96
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D. & Perucho, M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363, 558-561 (1993).
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 97
    • 84926434303 scopus 로고    scopus 로고
    • Inferring mutational timing and reconstructing tumour evolutionary histories
    • Turajlic, S., McGranahan, N. & Swanton, C. Inferring mutational timing and reconstructing tumour evolutionary histories. Biochim. Biophys. Acta 1855, 264-275 (2015).
    • (2015) Biochim. Biophys. Acta , vol.1855 , pp. 264-275
    • Turajlic, S.1    McGranahan, N.2    Swanton, C.3
  • 98
    • 84962900955 scopus 로고    scopus 로고
    • OncoNEM: Inferring tumor evolution from single-cell sequencing data
    • Ross, E. M. & Markowetz, F. OncoNEM: inferring tumor evolution from single-cell sequencing data. Genome Biol. 17, 69 (2016).
    • (2016) Genome Biol. , vol.17 , pp. 69
    • Ross, E.M.1    Markowetz, F.2
  • 99
    • 84887255230 scopus 로고    scopus 로고
    • Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer
    • Li, Y. et al. Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer. Gigascience 1, 12 (2012).
    • (2012) Gigascience , vol.1 , pp. 12
    • Li, Y.1
  • 100
    • 84863230091 scopus 로고    scopus 로고
    • Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor
    • Xu, X. et al. Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell 148, 886-895 (2012).
    • (2012) Cell , vol.148 , pp. 886-895
    • Xu, X.1
  • 101
  • 102
    • 84928823491 scopus 로고    scopus 로고
    • Using tumour phylogenetics to identify the roots of metastasis in humans
    • Naxerova, K. & Jain, R. K. Using tumour phylogenetics to identify the roots of metastasis in humans. Nat. Rev. Clin. Oncol. 12, 258-272 (2015).
    • (2015) Nat. Rev. Clin. Oncol. , vol.12 , pp. 258-272
    • Naxerova, K.1    Jain, R.K.2
  • 103
    • 48649106065 scopus 로고    scopus 로고
    • Cell lineage analysis of a mouse tumor
    • Frumkin, D. et al. Cell lineage analysis of a mouse tumor. Cancer Res. 68, 5924-5931 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 5924-5931
    • Frumkin, D.1
  • 104
    • 84864146822 scopus 로고    scopus 로고
    • Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability
    • Shlush, L. I. et al. Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability. Blood 120, 603-612 (2012).
    • (2012) Blood , vol.120 , pp. 603-612
    • Shlush, L.I.1
  • 105
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • Ding, L. et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 481, 506-510 (2012).
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1
  • 106
    • 84929991442 scopus 로고    scopus 로고
    • Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin
    • Martincorena, I. et al. Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin. Science 348, 880-886 (2015).
    • (2015) Science , vol.348 , pp. 880-886
    • Martincorena, I.1
  • 107
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida, S. et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467, 1114-1117 (2010).
    • (2010) Nature , vol.467 , pp. 1114-1117
    • Yachida, S.1
  • 108
    • 84863229772 scopus 로고    scopus 로고
    • Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm
    • Hou, Y. et al. Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell 148, 873-885 (2012).
    • (2012) Cell , vol.148 , pp. 873-885
    • Hou, Y.1
  • 109
    • 84919372228 scopus 로고    scopus 로고
    • Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics
    • Gawad, C., Koh, W. & Quake, S. R. Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics. Proc. Natl Acad. Sci. USA 111, 17947-17952 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 17947-17952
    • Gawad, C.1    Koh, W.2    Quake, S.R.3
  • 110
    • 84929661801 scopus 로고    scopus 로고
    • Advances and applications of single-cell sequencing technologies
    • Wang, Y. & Navin, N. E. Advances and applications of single-cell sequencing technologies. Mol. Cell 58, 598-609 (2015).
    • (2015) Mol. Cell , vol.58 , pp. 598-609
    • Wang, Y.1    Navin, N.E.2
  • 111
    • 18344396798 scopus 로고    scopus 로고
    • Comprehensive human genome amplification using multiple displacement amplification
    • Dean, F. B. et al. Comprehensive human genome amplification using multiple displacement amplification. Proc. Natl Acad. Sci. USA 99, 5261-5266 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 5261-5266
    • Dean, F.B.1
  • 112
    • 84864258558 scopus 로고    scopus 로고
    • Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm
    • Wang, J., Fan, H. C., Behr, B. & Quake, S. R. Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm. Cell 150, 402-412 (2012).
    • (2012) Cell , vol.150 , pp. 402-412
    • Wang, J.1    Fan, H.C.2    Behr, B.3    Quake, S.R.4
  • 113
    • 84942874388 scopus 로고    scopus 로고
    • Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification
    • Fu, Y. et al. Uniform and accurate single-cell sequencing based on emulsion whole-genome amplification. Proc. Natl Acad. Sci. USA 11 2, 11923-11928 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 11923-11928
    • Fu, Y.1
  • 114
    • 84965129052 scopus 로고    scopus 로고
    • Enhanced sequencing coverage with digital droplet multiple displacement amplification
    • Sidore, A. M., Lan, F., Lim, S. W. & Abate, A. R. Enhanced sequencing coverage with digital droplet multiple displacement amplification. Nucleic Acids Res. 44, e66 (2016).
    • (2016) Nucleic Acids Res. , vol.44 , pp. e66
    • Sidore, A.M.1    Lan, F.2    Lim, S.W.3    Abate, A.R.4
  • 115
    • 85016146681 scopus 로고    scopus 로고
    • Digital Droplet Multiple Displacement Amplification (ddMDA) for whole genome sequencing of limited DNA samples
    • Rhee, M., Light, Y. K., Meagher, R. J. & Singh, A. K. Digital Droplet Multiple Displacement Amplification (ddMDA) for whole genome sequencing of limited dna samples. PLoS ONE 11, e0153699 (2016).
    • (2016) PLoS ONE , vol.11 , pp. e0153699
    • Rhee, M.1    Light, Y.K.2    Meagher, R.J.3    Singh, A.K.4
  • 116
    • 84943170018 scopus 로고    scopus 로고
    • Single-cell genetic analysis using automated microfluidics to resolve somatic mosaicism
    • Szulwach, K. E. et al. Single-cell genetic analysis using automated microfluidics to resolve somatic mosaicism. PLoS ONE 10, e0135007 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0135007
    • Szulwach, K.E.1
  • 117
    • 2442707739 scopus 로고    scopus 로고
    • Tw o methods of whole-genome amplification enable accurate genotyping across a 2320-SNP linkage panel
    • Barker, D. L. et al. Tw o methods of whole-genome amplification enable accurate genotyping across a 2320-SNP linkage panel. Genome Res. 14, 901-907 (2004).
    • (2004) Genome Res. , vol.14 , pp. 901-907
    • Barker, D.L.1
  • 118
    • 84934980871 scopus 로고    scopus 로고
    • Quantitative assessment of single-cell whole genome amplification methods for detecting copy number variation using hippocampal neurons
    • Ning, L. et al. Quantitative assessment of single-cell whole genome amplification methods for detecting copy number variation using hippocampal neurons. Sci. Rep. 5, 11415 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 11415
    • Ning, L.1
  • 119
    • 84871461434 scopus 로고    scopus 로고
    • Genome-wide detection of single-nucleotide and copy-number variations of a single human cell
    • Zong, C., Lu, S., Chapman, A. R. & Xie, X. S. Genome-wide detection of single-nucleotide and copy-number variations of a single human cell. Science 338, 1622-1626 (2012).
    • (2012) Science , vol.338 , pp. 1622-1626
    • Zong, C.1    Lu, S.2    Chapman, A.R.3    Xie, X.S.4
  • 120
    • 84880213158 scopus 로고    scopus 로고
    • Single-cell paired-end genome sequencing reveals structural variation per cell cycle
    • Voet, T. et al. Single-cell paired-end genome sequencing reveals structural variation per cell cycle. Nucleic Acids Res. 41, 6119-6138 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. 6119-6138
    • Voet, T.1
  • 121
    • 84961369572 scopus 로고    scopus 로고
    • Highly multiplexed targeted DNA sequencing from single nuclei
    • Leung, M. L. et al. Highly multiplexed targeted DNA sequencing from single nuclei. Nat. Protoc. 11, 214-235 (2016).
    • (2016) Nat. Protoc. , vol.11 , pp. 214-235
    • Leung, M.L.1
  • 122
    • 84957790549 scopus 로고    scopus 로고
    • Genomic integrity and the ageing brain
    • Chow, H.-M. & Herrup, K. Genomic integrity and the ageing brain. Nat. Rev. Neurosci. 16, 672-684 (2015).
    • (2015) Nat. Rev. Neurosci. , vol.16 , pp. 672-684
    • Chow, H.-M.1    Herrup, K.2
  • 125
    • 84907200802 scopus 로고    scopus 로고
    • Single cell sequencing reveals low levels of aneuploidy across mammalian tissues
    • Knouse, K. A., Wu, J., Whittaker, C. A. & Amon, A. Single cell sequencing reveals low levels of aneuploidy across mammalian tissues. Proc. Natl Acad. Sci. USA 111, 13409-13414 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 13409-13414
    • Knouse, K.A.1    Wu, J.2    Whittaker, C.A.3    Amon, A.4
  • 126
    • 34548707114 scopus 로고    scopus 로고
    • Laser-capture microdissection
    • Espina, V. et al. Laser-capture microdissection. Nat. Protoc. 1, 586-603 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 586-603
    • Espina, V.1
  • 127
    • 62849099539 scopus 로고    scopus 로고
    • Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations
    • Gutierrez-Gonzalez, L. et al. Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations. J. Pathol. 217, 489-496 (2009).
    • (2009) J. Pathol. , vol.217 , pp. 489-496
    • Gutierrez-Gonzalez, L.1
  • 129
    • 77952243279 scopus 로고    scopus 로고
    • In situ detection and genotyping of individual mRNA molecules
    • Larsson, C., Grundberg, I., Söderberg, O. & Nilsson, M. In situ detection and genotyping of individual mRNA molecules. Nat. Methods 7, 395-397 (2010).
    • (2010) Nat. Methods , vol.7 , pp. 395-397
    • Larsson, C.1    Grundberg, I.2    Söderberg, O.3    Nilsson, M.4
  • 130
    • 13844283117 scopus 로고    scopus 로고
    • In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes
    • Larsson, C. et al. In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes. Nat. Methods 1, 227-232 (2004).
    • (2004) Nat. Methods , vol.1 , pp. 227-232
    • Larsson, C.1
  • 131
    • 84883459000 scopus 로고    scopus 로고
    • In situ sequencing for RNA analysis in preserved tissue and cells
    • Ke, R. et al. In situ sequencing for RNA analysis in preserved tissue and cells. Nat. Methods 10, 857-860 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 857-860
    • Ke, R.1
  • 132
    • 84897090228 scopus 로고    scopus 로고
    • Highly multiplexed subcellular RNA sequencing in situ
    • Lee, J. H. et al. Highly multiplexed subcellular RNA sequencing in situ. Science 343, 1360-1363 (2014).
    • (2014) Science , vol.343 , pp. 1360-1363
    • Lee, J.H.1
  • 133
    • 84923799606 scopus 로고    scopus 로고
    • Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues
    • Lee, J. H. et al. Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues. Nat. Protoc. 10, 442-458 (2015).
    • (2015) Nat. Protoc. , vol.10 , pp. 442-458
    • Lee, J.H.1
  • 134
    • 84942987073 scopus 로고    scopus 로고
    • In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer
    • Janiszewska, M. et al. In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer. Nat. Genet. 47, 1212-1219 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 1212-1219
    • Janiszewska, M.1
  • 135
    • 84929684999 scopus 로고    scopus 로고
    • Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
    • Macosko, E. Z. et al. Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets. Cell 161, 1202-1214 (2015).
    • (2015) Cell , vol.161 , pp. 1202-1214
    • MacOsko, E.Z.1
  • 136
    • 0032826750 scopus 로고    scopus 로고
    • Coexistence of widespread clones and large radial clones in early embryonic ferret cortex
    • Ware, M. L., Tavazoie, S. F., Reid, C. B. & Walsh, C. A. Coexistence of widespread clones and large radial clones in early embryonic ferret cortex. Cereb. Cortex 9, 636-645 (1999).
    • (1999) Cereb. Cortex , vol.9 , pp. 636-645
    • Ware, M.L.1    Tavazoie, S.F.2    Reid, C.B.3    Walsh, C.A.4
  • 137
    • 0030872579 scopus 로고    scopus 로고
    • Clonal dispersion and evidence for asymmetric cell division in ferret cortex
    • Reid, C. B., Tavazoie, S. F. & Walsh, C. A. Clonal dispersion and evidence for asymmetric cell division in ferret cortex. Development 124, 2441-2450 (1997).
    • (1997) Development , vol.124 , pp. 2441-2450
    • Reid, C.B.1    Tavazoie, S.F.2    Walsh, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.