Insertions and Deletions Target Lineage-Defining Genes in Human Cancers

Cell

Volumn 168, Issue 3, 2017, Pages 460-472.e14

  Imielinski, Marcin ^a,b   Guo, Guangwu ^c,d   Meyerson, Matthew ^c,d  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NEW YORK GENOME CENTER   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

cancer cell of origin; cancer genomics; noncoding genetic variation; somatic mutational processes; statistical driver discovery; variant topography; whole genome sequencing

Indexed keywords

ALBUMIN; PROTEIN H3K27AC; PROTEIN H3K36ME3; PROTEIN MIR21; PROTEIN VMP1; SURFACTANT PROTEIN SFTPA1; SURFACTANT PROTEIN SFTPB; SURFACTANT PROTEIN SFTPC; THYROGLOBULIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MEMBRANE PROTEIN; MICRORNA; MIRN21 MICRORNA, HUMAN; SURFACTANT ASSOCIATED PROTEIN; VMP1 PROTEIN, HUMAN;

ARTICLE; CANCER GENETICS; CANCER RECURRENCE; CANCER TISSUE; CELL LINEAGE; CHROMATIN; EPIGENETICS; GENE EXPRESSION; GENE TARGETING; GENETIC CODE; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; INDEL MUTATION; LIVER CELL CARCINOMA; LUNG ADENOCARCINOMA; MALIGNANT NEOPLASM; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN SECRETION; STOMACH CARCINOMA; THYROID CARCINOMA; WHOLE GENOME SEQUENCING; 3' UNTRANSLATED REGION; ADULT; AGED; FEMALE; GENETICS; MALE; MIDDLE AGED; MUTATION; NEOPLASM; NUCLEOTIDE MOTIF; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY;

3' UNTRANSLATED REGIONS; ADULT; AGED; AGED, 80 AND OVER; CELL LINEAGE; FEMALE; HUMANS; INDEL MUTATION; MALE; MEMBRANE PROTEINS; MICRORNAS; MIDDLE AGED; MUTATION; NEOPLASMS; NUCLEOTIDE MOTIFS; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY SURFACTANT-ASSOCIATED PROTEINS;

EID: 85009470013     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.12.025     Document Type: Article

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