-
1
-
-
40749161927
-
The molecular etiology of breast cancer: evidence from biomarkers of risk
-
Gaikwad NW, Yang L, Muti P, Meza JL, Pruthi S, Ingle JN, Rogan EG, Cavalieri EL. The molecular etiology of breast cancer: evidence from biomarkers of risk. Int J Cancer. 2008; 122:1949-1957.
-
(2008)
Int J Cancer
, vol.122
, pp. 1949-1957
-
-
Gaikwad, N.W.1
Yang, L.2
Muti, P.3
Meza, J.L.4
Pruthi, S.5
Ingle, J.N.6
Rogan, E.G.7
Cavalieri, E.L.8
-
2
-
-
0036793920
-
Tissue content of hydroxyestrogens in relation to survival of breast cancer patients
-
Castagnetta LA, Granata OM, Traina A, Ravazzolo B, Amoroso M, Miele M, Bellavia V, Agostara B, Carruba G. Tissue content of hydroxyestrogens in relation to survival of breast cancer patients. Clin Cancer Res. 2002; 8:3146-3155.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3146-3155
-
-
Castagnetta, L.A.1
Granata, O.M.2
Traina, A.3
Ravazzolo, B.4
Amoroso, M.5
Miele, M.6
Bellavia, V.7
Agostara, B.8
Carruba, G.9
-
3
-
-
0029865150
-
4-Hydroxylation of estrogens as marker of human mammary tumors
-
Liehr JG, Ricci MJ. 4-Hydroxylation of estrogens as marker of human mammary tumors. Proc Natl Acad Sci U S A. 1996; 93:3294-3296.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3294-3296
-
-
Liehr, J.G.1
Ricci, M.J.2
-
4
-
-
0038393297
-
Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer
-
Rogan EG, Badawi AF, Devanesan PD, Meza JL, Edney JA, West WW, Higginbotham SM, Cavalieri EL. Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer. Carcinogenesis. 2003; 24:697-702.
-
(2003)
Carcinogenesis
, vol.24
, pp. 697-702
-
-
Rogan, E.G.1
Badawi, A.F.2
Devanesan, P.D.3
Meza, J.L.4
Edney, J.A.5
West, W.W.6
Higginbotham, S.M.7
Cavalieri, E.L.8
-
5
-
-
33746847720
-
Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention
-
Cavalieri E, Chakravarti D, Guttenplan J, Hart E, Ingle J, Jankowiak R, Muti P, Rogan E, Russo J, Santen R, Sutter T. Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention. Biochim Biophys Acta. 2006; 1766:63-78.
-
(2006)
Biochim Biophys Acta
, vol.1766
, pp. 63-78
-
-
Cavalieri, E.1
Chakravarti, D.2
Guttenplan, J.3
Hart, E.4
Ingle, J.5
Jankowiak, R.6
Muti, P.7
Rogan, E.8
Russo, J.9
Santen, R.10
Sutter, T.11
-
6
-
-
10744225225
-
Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators
-
Cavalieri EL, Stack DE, Devanesan PD, Todorovic R, Dwivedy I, Higginbotham S, Johansson SL, Patil KD, Gross ML, Gooden JK, Ramanathan R, Cerny RL, Rogan EG. Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc Natl Acad Sci U S A. 1997; 94:10937-10942.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10937-10942
-
-
Cavalieri, E.L.1
Stack, D.E.2
Devanesan, P.D.3
Todorovic, R.4
Dwivedy, I.5
Higginbotham, S.6
Johansson, S.L.7
Patil, K.D.8
Gross, M.L.9
Gooden, J.K.10
Ramanathan, R.11
Cerny, R.L.12
Rogan, E.G.13
-
7
-
-
67650159397
-
Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats
-
Mense SM, Singh B, Remotti F, Liu X, Bhat HK. Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats. Carcinogenesis. 2009; 30:1202-1208.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1202-1208
-
-
Mense, S.M.1
Singh, B.2
Remotti, F.3
Liu, X.4
Bhat, H.K.5
-
8
-
-
83055176263
-
Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: a case study for breast cancer
-
Huang J, Sun J, Chen Y, Song Y, Dong L, Zhan Q, Zhang R, Abliz Z. Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: a case study for breast cancer. Analytica chimica acta. 2012; 711:60-68.
-
(2012)
Analytica chimica acta
, vol.711
, pp. 60-68
-
-
Huang, J.1
Sun, J.2
Chen, Y.3
Song, Y.4
Dong, L.5
Zhan, Q.6
Zhang, R.7
Abliz, Z.8
-
9
-
-
65549104414
-
4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: potential role of reactive oxygen species
-
Park SA, Na HK, Kim EH, Cha YN, Surh YJ. 4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: potential role of reactive oxygen species. Cancer Res. 2009; 69:2416-2424.
-
(2009)
Cancer Res
, vol.69
, pp. 2416-2424
-
-
Park, S.A.1
Na, H.K.2
Kim, E.H.3
Cha, Y.N.4
Surh, Y.J.5
-
10
-
-
35348981179
-
Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling
-
Li MH, Jang JH, Na HK, Cha YN, Surh YJ. Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. J Biol Chem. 2007; 282:28577-28586.
-
(2007)
J Biol Chem
, vol.282
, pp. 28577-28586
-
-
Li, M.H.1
Jang, J.H.2
Na, H.K.3
Cha, Y.N.4
Surh, Y.J.5
-
11
-
-
33750838526
-
Heme oxygenase-1 as a potential therapeutic target for hepatoprotection
-
Farombi EO, Surh YJ. Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. J Biochem Mol Biol. 2006; 39:479-491.
-
(2006)
J Biochem Mol Biol
, vol.39
, pp. 479-491
-
-
Farombi, E.O.1
Surh, Y.J.2
-
12
-
-
69949086594
-
Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress
-
Surh YJ, Kundu JK, Li MH, Na HK, Cha YN. Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress. Arch Pharm Res. 2009; 32:1163-1176.
-
(2009)
Arch Pharm Res
, vol.32
, pp. 1163-1176
-
-
Surh, Y.J.1
Kundu, J.K.2
Li, M.H.3
Na, H.K.4
Cha, Y.N.5
-
13
-
-
35848932314
-
Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice
-
Was H, Cichon T, Smolarczyk R, Rudnicka D, Stopa M, Chevalier C, Leger JJ, Lackowska B, Grochot A, Bojkowska K, Ratajska A, Kieda C, Szala S, et al. Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice. Am J Pathol. 2006; 169:2181-2198.
-
(2006)
Am J Pathol
, vol.169
, pp. 2181-2198
-
-
Was, H.1
Cichon, T.2
Smolarczyk, R.3
Rudnicka, D.4
Stopa, M.5
Chevalier, C.6
Leger, J.J.7
Lackowska, B.8
Grochot, A.9
Bojkowska, K.10
Ratajska, A.11
Kieda, C.12
Szala, S.13
-
14
-
-
49849099361
-
Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities
-
Loboda A, Jazwa A, Grochot-Przeczek A, Rutkowski AJ, Cisowski J, Agarwal A, Jozkowicz A, Dulak J. Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal. 2008; 10:1767-1812.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1767-1812
-
-
Loboda, A.1
Jazwa, A.2
Grochot-Przeczek, A.3
Rutkowski, A.J.4
Cisowski, J.5
Agarwal, A.6
Jozkowicz, A.7
Dulak, J.8
-
15
-
-
1942489300
-
Kaposi sarcoma-associated herpesvirus (KSHV) induces heme oxygenase-1 expression and activity in KSHV-infected endothelial cells
-
McAllister SC, Hansen SG, Ruhl RA, Raggo CM, DeFilippis VR, Greenspan D, Fruh K, Moses AV. Kaposi sarcoma-associated herpesvirus (KSHV) induces heme oxygenase-1 expression and activity in KSHV-infected endothelial cells. Blood. 2004; 103:3465-3473.
-
(2004)
Blood
, vol.103
, pp. 3465-3473
-
-
McAllister, S.C.1
Hansen, S.G.2
Ruhl, R.A.3
Raggo, C.M.4
DeFilippis, V.R.5
Greenspan, D.6
Fruh, K.7
Moses, A.V.8
-
16
-
-
70350221874
-
A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer
-
Alaoui-Jamali MA, Bismar TA, Gupta A, Szarek WA, Su J, Song W, Xu Y, Xu B, Liu G, Vlahakis JZ, Roman G, Jiao J, Schipper HM. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009; 69:8017-8024.
-
(2009)
Cancer Res
, vol.69
, pp. 8017-8024
-
-
Alaoui-Jamali, M.A.1
Bismar, T.A.2
Gupta, A.3
Szarek, W.A.4
Su, J.5
Song, W.6
Xu, Y.7
Xu, B.8
Liu, G.9
Vlahakis, J.Z.10
Roman, G.11
Jiao, J.12
Schipper, H.M.13
-
17
-
-
0038418359
-
In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor
-
Fang J, Sawa T, Akaike T, Akuta T, Sahoo SK, Khaled G, Hamada A, Maeda H. In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor. Cancer Res. 2003; 63:3567-3574.
-
(2003)
Cancer Res
, vol.63
, pp. 3567-3574
-
-
Fang, J.1
Sawa, T.2
Akaike, T.3
Akuta, T.4
Sahoo, S.K.5
Khaled, G.6
Hamada, A.7
Maeda, H.8
-
18
-
-
77955070858
-
Inhibition of heme oxygenase-1 enhances the cytotoxic effect of gemcitabine in urothelial cancer cells
-
Miyake M, Fujimoto K, Anai S, Ohnishi S, Nakai Y, Inoue T, Matsumura Y, Tomioka A, Ikeda T, Okajima E, Tanaka N, Hirao Y. Inhibition of heme oxygenase-1 enhances the cytotoxic effect of gemcitabine in urothelial cancer cells. Anticancer research. 2010; 30:2145-2152.
-
(2010)
Anticancer research
, vol.30
, pp. 2145-2152
-
-
Miyake, M.1
Fujimoto, K.2
Anai, S.3
Ohnishi, S.4
Nakai, Y.5
Inoue, T.6
Matsumura, Y.7
Tomioka, A.8
Ikeda, T.9
Okajima, E.10
Tanaka, N.11
Hirao, Y.12
-
19
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, Nabeshima Y. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun. 1997; 236:313-322.
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
20
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999; 13:76-86.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
21
-
-
33845648094
-
Redox regulation of neuronal survival mediated by electrophilic compounds
-
Satoh T, Lipton SA. Redox regulation of neuronal survival mediated by electrophilic compounds. Trends in neurosciences. 2007; 30:37-45.
-
(2007)
Trends in neurosciences
, vol.30
, pp. 37-45
-
-
Satoh, T.1
Lipton, S.A.2
-
22
-
-
38449111059
-
a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
-
Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y, Kitajima C, Cui J, Kamins J, Okamoto S, Izumi M, Shirasawa T, Lipton SA, et al. a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. Journal of neurochemistry. 2008; 104:1116-1131.
-
(2008)
Journal of neurochemistry
, vol.104
, pp. 1116-1131
-
-
Satoh, T.1
Kosaka, K.2
Itoh, K.3
Kobayashi, A.4
Yamamoto, M.5
Shimojo, Y.6
Kitajima, C.7
Cui, J.8
Kamins, J.9
Okamoto, S.10
Izumi, M.11
Shirasawa, T.12
Lipton, S.A.13
-
23
-
-
73849107705
-
Catechol estrogens mediated activation of Nrf2 through covalent modification of its quinone metabolite to Keap1
-
Sumi D, Numasawa Y, Endo A, Iwamoto N, Kumagai Y. Catechol estrogens mediated activation of Nrf2 through covalent modification of its quinone metabolite to Keap1. J Toxicol Sci. 2009; 34:627-635.
-
(2009)
J Toxicol Sci
, vol.34
, pp. 627-635
-
-
Sumi, D.1
Numasawa, Y.2
Endo, A.3
Iwamoto, N.4
Kumagai, Y.5
-
24
-
-
0141649274
-
Nrf2, not the estrogen receptor, mediates catechol estrogen-induced activation of the antioxidant responsive element
-
Lee JM, Anderson PC, Padgitt JK, Hanson JM, Waters CM, Johnson JA. Nrf2, not the estrogen receptor, mediates catechol estrogen-induced activation of the antioxidant responsive element. Biochimica et biophysica acta. 2003; 1629:92-101.
-
(2003)
Biochimica et biophysica acta
, vol.1629
, pp. 92-101
-
-
Lee, J.M.1
Anderson, P.C.2
Padgitt, J.K.3
Hanson, J.M.4
Waters, C.M.5
Johnson, J.A.6
-
25
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang DD, Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol. 2003; 23:8137-8151.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
26
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci U S A. 2002; 99:11908-11913.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
27
-
-
77649261371
-
Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains
-
Ogura T, Tong KI, Mio K, Maruyama Y, Kurokawa H, Sato C, Yamamoto M. Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains. Proc Natl Acad Sci U S A. 2010; 107:2842-2847.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2842-2847
-
-
Ogura, T.1
Tong, K.I.2
Mio, K.3
Maruyama, Y.4
Kurokawa, H.5
Sato, C.6
Yamamoto, M.7
-
28
-
-
0036269556
-
Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer
-
Costa C, Soares R, Reis-Filho JS, Leitao D, Amendoeira I, Schmitt FC. Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer. J Clin Pathol. 2002; 55:429-434.
-
(2002)
J Clin Pathol
, vol.55
, pp. 429-434
-
-
Costa, C.1
Soares, R.2
Reis-Filho, J.S.3
Leitao, D.4
Amendoeira, I.5
Schmitt, F.C.6
-
29
-
-
0036468899
-
Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer
-
Ristimaki A, Sivula A, Lundin J, Lundin M, Salminen T, Haglund C, Joensuu H, Isola J. Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer. Cancer Res. 2002; 62:632-635.
-
(2002)
Cancer Res
, vol.62
, pp. 632-635
-
-
Ristimaki, A.1
Sivula, A.2
Lundin, J.3
Lundin, M.4
Salminen, T.5
Haglund, C.6
Joensuu, H.7
Isola, J.8
-
30
-
-
80053002717
-
The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal
-
Banerjee P, Basu A, Datta D, Gasser M, Waaga-Gasser AM, Pal S. The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal. J Biol Chem. 2011; 286:33580-33590.
-
(2011)
J Biol Chem
, vol.286
, pp. 33580-33590
-
-
Banerjee, P.1
Basu, A.2
Datta, D.3
Gasser, M.4
Waaga-Gasser, A.M.5
Pal, S.6
-
31
-
-
21044452445
-
Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment
-
Berberat PO, Dambrauskas Z, Gulbinas A, Giese T, Giese N, Kunzli B, Autschbach F, Meuer S, Buchler MW, Friess H. Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment. Clin Cancer Res. 2005; 11:3790-3798.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3790-3798
-
-
Berberat, P.O.1
Dambrauskas, Z.2
Gulbinas, A.3
Giese, T.4
Giese, N.5
Kunzli, B.6
Autschbach, F.7
Meuer, S.8
Buchler, M.W.9
Friess, H.10
-
32
-
-
35848942608
-
Heme oxygenase-1 in tumors: is it a false friend?
-
Jozkowicz A, Was H, Dulak J. Heme oxygenase-1 in tumors: is it a false friend? Antioxid Redox Signal. 2007; 9:2099-2117.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2099-2117
-
-
Jozkowicz, A.1
Was, H.2
Dulak, J.3
-
33
-
-
79960060305
-
Oncogeneinduced Nrf2 transcription promotes ROS detoxification and tumorigenesis
-
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, Hruban RH, et al. Oncogeneinduced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature. 2011; 475:106-109.
-
(2011)
Nature
, vol.475
, pp. 106-109
-
-
DeNicola, G.M.1
Karreth, F.A.2
Humpton, T.J.3
Gopinathan, A.4
Wei, C.5
Frese, K.6
Mangal, D.7
Yu, K.H.8
Yeo, C.J.9
Calhoun, E.S.10
Scrimieri, F.11
Winter, J.M.12
Hruban, R.H.13
-
34
-
-
79551590643
-
Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder
-
Miyake M, Fujimoto K, Anai S, Ohnishi S, Kuwada M, Nakai Y, Inoue T, Matsumura Y, Tomioka A, Ikeda T, Tanaka N, Hirao Y. Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder. Oncol Rep. 2011; 25:653-660.
-
(2011)
Oncol Rep
, vol.25
, pp. 653-660
-
-
Miyake, M.1
Fujimoto, K.2
Anai, S.3
Ohnishi, S.4
Kuwada, M.5
Nakai, Y.6
Inoue, T.7
Matsumura, Y.8
Tomioka, A.9
Ikeda, T.10
Tanaka, N.11
Hirao, Y.12
-
35
-
-
84939164897
-
Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy
-
Tan Q, Wang H, Hu Y, Hu M, Li X, Aodengqimuge, Ma Y, Wei C, Song L. Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy. Cancer science. 2015.
-
(2015)
Cancer science
-
-
Tan, Q.1
Wang, H.2
Hu, Y.3
Hu, M.4
Li, X.5
Aodengqimuge, M.Y.6
Wei, C.7
Song, L.8
-
36
-
-
64349099334
-
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS
-
Kim DH, Kim JH, Kim EH, Na HK, Cha YN, Chung JH, Surh YJ. 15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. Carcinogenesis. 2009; 30:645-654.
-
(2009)
Carcinogenesis
, vol.30
, pp. 645-654
-
-
Kim, D.H.1
Kim, J.H.2
Kim, E.H.3
Na, H.K.4
Cha, Y.N.5
Chung, J.H.6
Surh, Y.J.7
-
37
-
-
33744961436
-
Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor
-
Marinissen MJ, Tanos T, Bolos M, de Sagarra MR, Coso OA, Cuadrado A. Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor. J Biol Chem. 2006; 281:11332-11346.
-
(2006)
J Biol Chem
, vol.281
, pp. 11332-11346
-
-
Marinissen, M.J.1
Tanos, T.2
Bolos, M.3
de Sagarra, M.R.4
Coso, O.A.5
Cuadrado, A.6
-
38
-
-
0842308157
-
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin
-
Fang J, Sawa T, Akaike T, Greish K, Maeda H. Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin. Int J Cancer. 2004; 109:1-8.
-
(2004)
Int J Cancer
, vol.109
, pp. 1-8
-
-
Fang, J.1
Sawa, T.2
Akaike, T.3
Greish, K.4
Maeda, H.5
-
39
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers
-
Wakabayashi N, Dinkova-Kostova AT, Holtzclaw WD, Kang MI, Kobayashi A, Yamamoto M, Kensler TW, Talalay P. Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers. Proc Natl Acad Sci U S A. 2004; 101:2040-2045.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.I.4
Kobayashi, A.5
Yamamoto, M.6
Kensler, T.W.7
Talalay, P.8
-
41
-
-
33344469643
-
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
-
Kobayashi A, Kang MI, Watai Y, Tong KI, Shibata T, Uchida K, Yamamoto M. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol. 2006; 26:221-229.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 221-229
-
-
Kobayashi, A.1
Kang, M.I.2
Watai, Y.3
Tong, K.I.4
Shibata, T.5
Uchida, K.6
Yamamoto, M.7
-
42
-
-
33344463325
-
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model
-
Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, Yamamoto M. Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model. Mol Cell Biol. 2006; 26:2887-2900.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2887-2900
-
-
Tong, K.I.1
Katoh, Y.2
Kusunoki, H.3
Itoh, K.4
Tanaka, T.5
Yamamoto, M.6
-
43
-
-
0038663090
-
Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cysteine ligase modulatory gene expression in HepG2 cells
-
Zipper LM, Mulcahy RT. Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cysteine ligase modulatory gene expression in HepG2 cells. Toxicol Sci. 2003; 73:124-134.
-
(2003)
Toxicol Sci
, vol.73
, pp. 124-134
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
44
-
-
0034704079
-
Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism
-
Yu R, Chen C, Mo YY, Hebbar V, Owuor ED, Tan TH, Kong AN. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J Biol Chem. 2000; 275:39907-39913.
-
(2000)
J Biol Chem
, vol.275
, pp. 39907-39913
-
-
Yu, R.1
Chen, C.2
Mo, Y.Y.3
Hebbar, V.4
Owuor, E.D.5
Tan, T.H.6
Kong, A.N.7
-
45
-
-
0035212419
-
Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)
-
Kong AN, Owuor E, Yu R, Hebbar V, Chen C, Hu R, Mandlekar S. Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). Drug Metab Rev. 2001; 33:255-271.
-
(2001)
Drug Metab Rev
, vol.33
, pp. 255-271
-
-
Kong, A.N.1
Owuor, E.2
Yu, R.3
Hebbar, V.4
Chen, C.5
Hu, R.6
Mandlekar, S.7
-
46
-
-
0037174917
-
Induction of heme oxygenase 1 by nitrosative stress. A role for nitroxyl anion
-
Naughton P, Foresti R, Bains SK, Hoque M, Green CJ, Motterlini R. Induction of heme oxygenase 1 by nitrosative stress. A role for nitroxyl anion. J Biol Chem. 2002; 277:40666-40674.
-
(2002)
J Biol Chem
, vol.277
, pp. 40666-40674
-
-
Naughton, P.1
Foresti, R.2
Bains, S.K.3
Hoque, M.4
Green, C.J.5
Motterlini, R.6
-
47
-
-
14644397177
-
Super-induction of HO-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production
-
Srisook K, Cha YN. Super-induction of HO-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production. Nitric Oxide. 2005; 12:70-79.
-
(2005)
Nitric Oxide
, vol.12
, pp. 70-79
-
-
Srisook, K.1
Cha, Y.N.2
-
48
-
-
80052175098
-
STAT5A expression in Swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system
-
Stewart WC, Pearcy LA, Floyd ZE, Stephens JM. STAT5A expression in Swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system. Obesity. 2011; 19:1731-1734.
-
(2011)
Obesity
, vol.19
, pp. 1731-1734
-
-
Stewart, W.C.1
Pearcy, L.A.2
Floyd, Z.E.3
Stephens, J.M.4
-
49
-
-
79960835354
-
Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole
-
Abiko Y, Miura T, Phuc BH, Shinkai Y, Kumagai Y. Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole. Toxicol Appl Pharmacol. 2011; 255:32-39.
-
(2011)
Toxicol Appl Pharmacol
, vol.255
, pp. 32-39
-
-
Abiko, Y.1
Miura, T.2
Phuc, B.H.3
Shinkai, Y.4
Kumagai, Y.5
-
50
-
-
33745728903
-
Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity
-
Kundu JK, Shin YK, Kim SH, Surh YJ. Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity. Carcinogenesis. 2006; 27:1465-1474.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1465-1474
-
-
Kundu, J.K.1
Shin, Y.K.2
Kim, S.H.3
Surh, Y.J.4
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