메뉴 건너뛰기




Volumn 1629, Issue 1-3, 2003, Pages 92-101

Nrf2, not the estrogen receptor, mediates catechol estrogen-induced activation of the antioxidant responsive element

Author keywords

Antioxidant responsive element; Catechol estrogen; ER; Nrf2; PI3 kinase

Indexed keywords

2 HYDROXYESTRADIOL; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 HYDROXYESTRADIOL; CATECHOL ESTROGEN; ESTRADIOL; ESTROGEN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NF E2 RELATED FACTOR; UNCLASSIFIED DRUG;

EID: 0141649274     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2003.08.006     Document Type: Article
Times cited : (41)

References (42)
  • 1
    • 0025948113 scopus 로고
    • The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
    • Rushmore T.H., Morton M.R., Pickett C.B. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J. Biol. Chem. 266:1991;11632-11639.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11632-11639
    • Rushmore, T.H.1    Morton, M.R.2    Pickett, C.B.3
  • 2
    • 0037192626 scopus 로고    scopus 로고
    • Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
    • Bloom D., Dhakshinamoorthy S., Jaiswal A.K. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene. 21:2002;2191-2200.
    • (2002) Oncogene , vol.21 , pp. 2191-2200
    • Bloom, D.1    Dhakshinamoorthy, S.2    Jaiswal, A.K.3
  • 3
    • 0035034848 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells
    • Kang K.W., Cho M.K., Lee C.H., Kim S.G. Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells. Mol. Pharmacol. 59:2001;1147-1156.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1147-1156
    • Kang, K.W.1    Cho, M.K.2    Lee, C.H.3    Kim, S.G.4
  • 4
    • 0034687543 scopus 로고    scopus 로고
    • Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes
    • Zipper L.M., Mulcahy R.T. Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes. Biochem. Biophys. Res. Commun. 278:2000;484-492.
    • (2000) Biochem. Biophys. Res. Commun. , vol.278 , pp. 484-492
    • Zipper, L.M.1    Mulcahy, R.T.2
  • 5
    • 0035827505 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells
    • Lee J.M., Hanson J.M., Chu W.A., Johnson J.A. Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells. J. Biol. Chem. 276:2001;20011-20016.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20011-20016
    • Lee, J.M.1    Hanson, J.M.2    Chu, W.A.3    Johnson, J.A.4
  • 6
    • 0034805627 scopus 로고    scopus 로고
    • Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells
    • Lee J.M., Moehlenkamp J.D., Hanson J.M., Johnson J.A. Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells. Biochem. Biophys. Res. Commun. 280:2001;286-292.
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 286-292
    • Lee, J.M.1    Moehlenkamp, J.D.2    Hanson, J.M.3    Johnson, J.A.4
  • 7
    • 0037106099 scopus 로고    scopus 로고
    • Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
    • Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 62:2002;5196-5203.
    • (2002) Cancer Res. , vol.62 , pp. 5196-5203
    • Thimmulappa, R.K.1    Mai, K.H.2    Srisuma, S.3    Kensler, T.W.4    Yamamoto, M.5    Biswal, S.6
  • 8
    • 0038146898 scopus 로고    scopus 로고
    • Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
    • Lee J.M., Calkins M.J., Chan K., Kan Y.W., Johnson J.A. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J. Biol. Chem. 278:2003;12029-12038.
    • (2003) J. Biol. Chem. , vol.278 , pp. 12029-12038
    • Lee, J.M.1    Calkins, M.J.2    Chan, K.3    Kan, Y.W.4    Johnson, J.A.5
  • 9
    • 0028061444 scopus 로고
    • Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
    • Moi P., Chan K., Asunis I., Cao A., Kan Y.W. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc. Natl. Acad. Sci. U. S. A. 91:1994;9926-9930.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 9926-9930
    • Moi, P.1    Chan, K.2    Asunis, I.3    Cao, A.4    Kan, Y.W.5
  • 11
    • 0034623211 scopus 로고    scopus 로고
    • Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
    • Alam J., Wicks C., Stewart D., Gong P., Touchard C., Otterbein S., Choi A.M., Burow M.E., Tou J. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J. Biol. Chem. 275:2000;27694-27702.
    • (2000) J. Biol. Chem. , vol.275 , pp. 27694-27702
    • Alam, J.1    Wicks, C.2    Stewart, D.3    Gong, P.4    Touchard, C.5    Otterbein, S.6    Choi, A.M.7    Burow, M.E.8    Tou, J.9
  • 12
    • 0037044791 scopus 로고    scopus 로고
    • Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
    • Huang H.C., Nguyen T., Pickett C.B. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J. Biol. Chem. 277:2002;42769-42774.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42769-42774
    • Huang, H.C.1    Nguyen, T.2    Pickett, C.B.3
  • 13
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13:1999;76-86.
    • (1999) Genes Dev. , vol.13 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 14
    • 0013282861 scopus 로고    scopus 로고
    • Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome
    • Nguyen T., Sherratt P.J., Huang H.C., Yang C.S., Pickett C.B. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome. J. Biol. Chem. 278:2003;4536-4541.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4536-4541
    • Nguyen, T.1    Sherratt, P.J.2    Huang, H.C.3    Yang, C.S.4    Pickett, C.B.5
  • 15
    • 0037821802 scopus 로고    scopus 로고
    • Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
    • McMahon M., Itoh K., Yamamoto M., Hayes J.D. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J. Biol. Chem. 278:2003;21592-21600.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21592-21600
    • McMahon, M.1    Itoh, K.2    Yamamoto, M.3    Hayes, J.D.4
  • 17
  • 18
    • 0025047078 scopus 로고
    • Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor
    • Weisz A., Rosales R. Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor. Nucleic Acids Res. 18:1990;5097-5106.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5097-5106
    • Weisz, A.1    Rosales, R.2
  • 19
    • 0028901194 scopus 로고
    • Tamoxifen activation of the estrogen receptor/AP-1 pathway: Potential origin for the cell-specific estrogen-like effects of antiestrogens
    • Webb P., Lopez G.N., Uht R.M., Kushner P.J. Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens. Mol. Endocrinol. 9:1995;443-456.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 443-456
    • Webb, P.1    Lopez, G.N.2    Uht, R.M.3    Kushner, P.J.4
  • 21
    • 0028287546 scopus 로고
    • Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells
    • Krishnan V., Wang X., Safe S. Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells. J. Biol. Chem. 269:1994;15912-15917.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15912-15917
    • Krishnan, V.1    Wang, X.2    Safe, S.3
  • 22
    • 0032566547 scopus 로고    scopus 로고
    • Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-alpha and estrogen receptor-beta
    • Montano M.M., Jaiswal A.K., Katzenellenbogen B.S. Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-alpha and estrogen receptor-beta. J. Biol. Chem. 273:1998;25443-25449.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25443-25449
    • Montano, M.M.1    Jaiswal, A.K.2    Katzenellenbogen, B.S.3
  • 23
    • 0030898711 scopus 로고    scopus 로고
    • The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens
    • Montano M.M., Katzenellenbogen B.S. The quinone reductase gene: a unique estrogen receptor-regulated gene that is activated by antiestrogens. Proc. Natl. Acad. Sci. U. S. A. 94:1997;2581-2586.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 2581-2586
    • Montano, M.M.1    Katzenellenbogen, B.S.2
  • 24
    • 0034602152 scopus 로고    scopus 로고
    • Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity
    • Montano M.M., Wittmann B.M., Bianco N.R. Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity. J. Biol. Chem. 275:2000;34306-34313.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34306-34313
    • Montano, M.M.1    Wittmann, B.M.2    Bianco, N.R.3
  • 25
    • 0033118665 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
    • Singer C.A., Figueroa-Masot X.A., Batchelor R.H., Dorsa D.M. The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J. Neurosci. 19:1999;2455-2463.
    • (1999) J. Neurosci. , vol.19 , pp. 2455-2463
    • Singer, C.A.1    Figueroa-Masot, X.A.2    Batchelor, R.H.3    Dorsa, D.M.4
  • 26
    • 0031021372 scopus 로고    scopus 로고
    • 17 alpha-estradiol exerts neuroprotective effects on SK-N-SH cells
    • Green P.S., Bishop J., Simpkins J.W. 17 alpha-estradiol exerts neuroprotective effects on SK-N-SH cells. J. Neurosci. 17:1997;511-515.
    • (1997) J. Neurosci. , vol.17 , pp. 511-515
    • Green, P.S.1    Bishop, J.2    Simpkins, J.W.3
  • 27
    • 0033529941 scopus 로고    scopus 로고
    • The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties
    • Moosmann B., Behl C. The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties. Proc. Natl. Acad. Sci. U. S. A. 96:1999;8867-8872.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 8867-8872
    • Moosmann, B.1    Behl, C.2
  • 28
    • 0037016759 scopus 로고    scopus 로고
    • Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells
    • Li J., Lee J.M., Johnson J.A. Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J. Biol. Chem. 277:2002;388-394.
    • (2002) J. Biol. Chem. , vol.277 , pp. 388-394
    • Li, J.1    Lee, J.M.2    Johnson, J.A.3
  • 29
    • 0036319473 scopus 로고    scopus 로고
    • Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice
    • Johnson D.A., Andrews G.K., Xu W., Johnson J.A. Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice. J. Neurochem. 81:2002;1233-1241.
    • (2002) J. Neurochem. , vol.81 , pp. 1233-1241
    • Johnson, D.A.1    Andrews, G.K.2    Xu, W.3    Johnson, J.A.4
  • 30
    • 0033102622 scopus 로고    scopus 로고
    • Activation of antioxidant/electrophile-responsive elements in IMR-32 human neuroblastoma cells
    • Moehlenkamp J.D., Johnson J.A. Activation of antioxidant/electrophile-responsive elements in IMR-32 human neuroblastoma cells. Arch. Biochem. Biophys. 363:1999;98-106.
    • (1999) Arch. Biochem. Biophys. , vol.363 , pp. 98-106
    • Moehlenkamp, J.D.1    Johnson, J.A.2
  • 31
    • 0030451213 scopus 로고    scopus 로고
    • NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
    • Chan K., Lu R., Chang J.C., Kan Y.W. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc. Natl. Acad. Sci. U. S. A. 93:1996;13943-13948.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 13943-13948
    • Chan, K.1    Lu, R.2    Chang, J.C.3    Kan, Y.W.4
  • 32
    • 0042330074 scopus 로고    scopus 로고
    • Identifcation of a novel Nrf2-regulated antioxidant response element in the mouse NAD(P)H:quinone oxidoreductase 1 gene; Reassessment of the ARE consensus sequence
    • Nioi P., McMahon M., Itoh K., Yamamoto M., Hayes J.D. Identifcation of a novel Nrf2-regulated antioxidant response element in the mouse NAD(P)H:quinone oxidoreductase 1 gene; reassessment of the ARE consensus sequence. Biochem. J. 20:2003.
    • (2003) Biochem. J. , vol.20
    • Nioi, P.1    McMahon, M.2    Itoh, K.3    Yamamoto, M.4    Hayes, J.D.5
  • 33
    • 0034704079 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism
    • Yu R., Chen C., Mo Y.Y., Hebbar V., Owuor E.D., Tan T.H., Kong A.N. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J. Biol. Chem. 275:2000;39907-39913.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39907-39913
    • Yu, R.1    Chen, C.2    Mo, Y.Y.3    Hebbar, V.4    Owuor, E.D.5    Tan, T.H.6    Kong, A.N.7
  • 34
    • 0035199904 scopus 로고    scopus 로고
    • Regulation of human apolipoprotein A-I gene expression by equine estrogens
    • Zhang X., Jiao J.J., Bhavnani B.R., Tam S.P. Regulation of human apolipoprotein A-I gene expression by equine estrogens. J. Lipid Res. 42:2001;1789-1800.
    • (2001) J. Lipid Res. , vol.42 , pp. 1789-1800
    • Zhang, X.1    Jiao, J.J.2    Bhavnani, B.R.3    Tam, S.P.4
  • 37
    • 0031816540 scopus 로고    scopus 로고
    • Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists
    • Barkhem T., Carlsson B., Nilsson Y., Enmark E., Gustafsson J., Nilsson S. Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists. Mol. Pharmacol. 54:1998;105-112.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 105-112
    • Barkhem, T.1    Carlsson, B.2    Nilsson, Y.3    Enmark, E.4    Gustafsson, J.5    Nilsson, S.6
  • 38
    • 0025695290 scopus 로고
    • Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex
    • Gaub M.P., Bellard M., Scheuer I., Chambon P., Sassone-Corsi P. Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell. 63:1990;1267-1276.
    • (1990) Cell , vol.63 , pp. 1267-1276
    • Gaub, M.P.1    Bellard, M.2    Scheuer, I.3    Chambon, P.4    Sassone-Corsi, P.5
  • 40
    • 0034752461 scopus 로고    scopus 로고
    • Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
    • Katoh Y., Itoh K., Yoshida E., Miyagishi M., Fukamizu A., Yamamoto M. Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells. 6:2001;857-868.
    • (2001) Genes Cells , vol.6 , pp. 857-868
    • Katoh, Y.1    Itoh, K.2    Yoshida, E.3    Miyagishi, M.4    Fukamizu, A.5    Yamamoto, M.6
  • 41
    • 0037996661 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
    • Shih A.Y., Johnson D.A., Wong G., Kraft A.D., Jiang L., Erb H., Johnson J.A., Murphy T.H. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J. Neurosci. 23:2003;3394-3406.
    • (2003) J. Neurosci. , vol.23 , pp. 3394-3406
    • Shih, A.Y.1    Johnson, D.A.2    Wong, G.3    Kraft, A.D.4    Jiang, L.5    Erb, H.6    Johnson, J.A.7    Murphy, T.H.8
  • 42
    • 0035217151 scopus 로고    scopus 로고
    • Effect of two mutations of human CYP1B1, G61E and R469W, on stability and endogenous steroid substrate metabolism
    • Jansson I., Stoilov I., Sarfarazi M., Schenkman J.B. Effect of two mutations of human CYP1B1, G61E and R469W, on stability and endogenous steroid substrate metabolism. Pharmacogenetics. 11:2001;793-801.
    • (2001) Pharmacogenetics , vol.11 , pp. 793-801
    • Jansson, I.1    Stoilov, I.2    Sarfarazi, M.3    Schenkman, J.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.