STAT5A expression in swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system

Obesity

Volumn 19, Issue 9, 2011, Pages 1731-1734

  Stewart, William C ^a   Pearcy, Lisa A ^a   Floyd, Z Elizabeth ^b   Stephens, Jacqueline M ^c  

^a MIDDLE TENNESSEE STATE UNIVERSITY   (United States)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^c LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETROVIRUS VECTOR; STAT5A PROTEIN;

ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN 3T3; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPIDIDYMIS FAT; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION; VIRAL GENE DELIVERY SYSTEM;

3T3 CELLS; ADIPOGENESIS; ADIPONECTIN; ADIPOSE TISSUE, WHITE; ANIMALS; BIOLOGICAL MARKERS; FIBROBLASTS; MICE; MICE, NUDE; MODELS, BIOLOGICAL; PPAR GAMMA; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; STAT5 TRANSCRIPTION FACTOR; SWISS 3T3 CELLS;

ANIMALIA; MURINAE; MUS;

EID: 80052175098     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.66     Document Type: Article

References (17)

1. Stephens JM, Morrison RF, Pilch PF. The expression and regulation of STATs during 3T3-L1 adipocyte differentiation. J Biol Chem 1996;271: 10441-10444. (Pubitemid 26149888)
2. Harp JB, Franklin D, Vanderpuije AA, Gimble JM. Differential expression of signal transducers and activators of transcription during human adipogenesis. Biochem Biophys Res Commun 2001;281:907-912. (Pubitemid 32923057)
3. Wu Z, Bucher NL, Farmer SR. Induction of peroxisome proliferator- activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids. Mol Cell Biol 1996;16:4128-4136. (Pubitemid 26251212)
4. Stephens JM, Morrison RF, Wu Z, Farmer SR. PPARgamma liganddependent induction of STAT1, STAT5A, and STAT5B during adipogenesis. Biochem Biophys Res Commun 1999;262:216-222. (Pubitemid 29412650)
5. Stewart WC, Morrison RF, Young SL, Stephens JM. Regulation of signal transducers and activators of transcription (STATs) by effectors of adipogenesis: coordinate regulation of STATs 1, 5A, and 5B with peroxisome proliferator-activated receptor-gamma and C/AAAT enhancer binding protein-alpha. Biochim Biophys Acta 1999;1452:188-196. (Pubitemid 29528266)
6. Yarwood SJ, Sale EM, Sale GJ et al. Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase/signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signaling. J Biol Chem 1999;274:8662-8668. (Pubitemid 29164661)
7. Shang CA, Waters MJ. Constitutively active signal transducer and activator of transcription 5 can replace the requirement for growth hormone in adipogenesis of 3T3-F442A preadipocytes. Mol Endocrinol 2003;17:2494-2508. (Pubitemid 37542212)
8. Nanbu-Wakao R, Morikawa Y, Matsumura I et al. Stimulation of 3T3-L1 adipogenesis by signal transducer and activator of transcription 5. Mol Endocrinol 2002;16:1565-1576. (Pubitemid 34743675)
9. Floyd ZE, Stephens JM. STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation. Diabetes 2003;52:308-314. (Pubitemid 36173183)
10. Baugh JE Jr, Floyd ZE, Stephens JM. The modulation of STAT5A/GR complexes during fat cell differentiation and in mature adipocytes. Obesity (Silver Spring) 2007;15:583-590. (Pubitemid 46643310)
11. Teglund S, McKay C, Schuetz E et al. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 1998;93:841-850. (Pubitemid 28257589)
12. Green H, Kehinde O. Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line. J Cell Physiol 1979;101:169-171. (Pubitemid 10196616)
13. Mandrup S, Loftus TM, MacDougald OA, Kuhajda FP, Lane MD. Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc Natl Acad Sci USA 1997;94:4300-4305. (Pubitemid 27194236)
14. Jing W, Lin Y, Wu L et al. Ectopic adipogenesis of preconditioned adiposederived stromal cells in an alginate system. Cell Tissue Res 2007;330: 567-572. (Pubitemid 350098210)
15. Morgenstern JP, Land H. A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells. Nucleic Acids Res 1990;18:1068. (Pubitemid 20089500)
16. Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 1993;90:8392-8396. (Pubitemid 23277674)
17. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.