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Volumn 30, Issue 7, 2009, Pages 1202-1208

Vitamin C and α-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYESTRADIOL; 4 HYDROXYESTRADIOL; ALPHA NAPHTHOFLAVONE; ASCORBIC ACID; ESTRADIOL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; SUPEROXIDE DISMUTASE;

EID: 67650159397     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp093     Document Type: Article
Times cited : (42)

References (50)
  • 1
    • 0034099083 scopus 로고    scopus 로고
    • Hormonal carcinogenesis
    • Henderson,B.E. et al. (2000) Hormonal carcinogenesis. Carcinogenesis, 21, 427-433.
    • (2000) Carcinogenesis , vol.21 , pp. 427-433
    • Henderson, B.E.1
  • 4
    • 0038032435 scopus 로고    scopus 로고
    • National Toxicology Program, National Toxicology Program, Research Triangle Park, NC
    • National Toxicology Program. (2002) Report on Carcinogens. National Toxicology Program, Research Triangle Park, NC.
    • (2002) Report on Carcinogens
  • 5
    • 0037123341 scopus 로고    scopus 로고
    • Endogenous sex hormones and breast cancer in postmenopausal women: Reanalysis of nine prospective studies
    • Key,T. et al. (2002) Endogenous sex hormones and breast cancer in postmenopausal women: Reanalysis of nine prospective studies. J. Natl Cancer Inst., 94, 606-616.
    • (2002) J. Natl Cancer Inst , vol.94 , pp. 606-616
    • Key, T.1
  • 6
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager,J.D. et al. (2006) Estrogen carcinogenesis in breast cancer. N. Engl. J. Med., 354, 270-282.
    • (2006) N. Engl. J. Med , vol.354 , pp. 270-282
    • Yager, J.D.1
  • 7
    • 0037389607 scopus 로고    scopus 로고
    • Critical role of oxidative stress in estrogen-induced carcinogenesis
    • Bhat,H.K. et al. (2003) Critical role of oxidative stress in estrogen-induced carcinogenesis. Proc. Natl Acad. Sci. USA, 100 3913-3918.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 3913-3918
    • Bhat, H.K.1
  • 8
    • 14944354257 scopus 로고    scopus 로고
    • A unifying mechanism in the initiation of cancer and other diseases by catechol quinones
    • Cavalieri,E.L. et al. (2004) A unifying mechanism in the initiation of cancer and other diseases by catechol quinones. Ann. N. Y. Acad. Sci., 1028, 247-257.
    • (2004) Ann. N. Y. Acad. Sci , vol.1028 , pp. 247-257
    • Cavalieri, E.L.1
  • 9
    • 0033535424 scopus 로고    scopus 로고
    • Estrogen, DNA damage and mutations
    • Roy,D. et al. (1999) Estrogen, DNA damage and mutations. Mutat. Res., 424, 107-115.
    • (1999) Mutat. Res , vol.424 , pp. 107-115
    • Roy, D.1
  • 10
    • 0033655698 scopus 로고    scopus 로고
    • Endogenous estrogens as carcinogens through metabolic activation
    • Yager,J.D. (2000) Endogenous estrogens as carcinogens through metabolic activation. J. Natl Cancer Inst. Monogr., 27, 67-73.
    • (2000) J. Natl Cancer Inst. Monogr , vol.27 , pp. 67-73
    • Yager, J.D.1
  • 11
    • 2942517697 scopus 로고    scopus 로고
    • Somatic mutations in stilbene estrogen-induced Syrian hamster kidney tumors identified by DNA fingerprinting
    • Singh,K.P. et al. (2004) Somatic mutations in stilbene estrogen-induced Syrian hamster kidney tumors identified by DNA fingerprinting. J. Carcinog., 3, 4.
    • (2004) J. Carcinog , vol.3 , pp. 4
    • Singh, K.P.1
  • 12
    • 0033655310 scopus 로고    scopus 로고
    • Estrogens as endogenous genotoxic agents - DNA adducts and mutations
    • Cavalieri,E. et al. (2000) Estrogens as endogenous genotoxic agents - DNA adducts and mutations. J. Natl Cancer Inst. Monogr., 27, 75-93.
    • (2000) J. Natl Cancer Inst. Monogr , vol.27 , pp. 75-93
    • Cavalieri, E.1
  • 13
    • 0034646213 scopus 로고    scopus 로고
    • Rat strain-specific actions of 17beta-estradiol in the mammary gland: Correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers
    • Harvell,D.M. et al. (2000) Rat strain-specific actions of 17beta-estradiol in the mammary gland: Correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers. Proc. Natl Acad. Sci. USA, 97 2779-2784.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 2779-2784
    • Harvell, D.M.1
  • 14
    • 0031419014 scopus 로고    scopus 로고
    • Ovary-intact, but not ovariectomized female ACI rats treated with 17beta-estradiol rapidly develop mammary carcinoma
    • Shull,J.D. et al. (1997) Ovary-intact, but not ovariectomized female ACI rats treated with 17beta-estradiol rapidly develop mammary carcinoma. Carcinogenesis, 18, 1595-1601.
    • (1997) Carcinogenesis , vol.18 , pp. 1595-1601
    • Shull, J.D.1
  • 15
    • 0035662989 scopus 로고    scopus 로고
    • Intratumoral variations in DNA ploidy and s-phase fraction in human breast cancer
    • Arnerlov,C. et al. (2001) Intratumoral variations in DNA ploidy and s-phase fraction in human breast cancer. Anal. Cell. Pathol., 23, 21-28.
    • (2001) Anal. Cell. Pathol , vol.23 , pp. 21-28
    • Arnerlov, C.1
  • 16
    • 0036144435 scopus 로고    scopus 로고
    • Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: Comparison to invasive human ductal breast cancer
    • Li,J.J. et al. (2002) Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: Comparison to invasive human ductal breast cancer. Mol. Carcinog., 33, 56-65.
    • (2002) Mol. Carcinog , vol.33 , pp. 56-65
    • Li, J.J.1
  • 17
    • 11144228109 scopus 로고    scopus 로고
    • Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats
    • Li,J.J. et al. (2004) Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats. Proc. Natl Acad. Sci. USA, 101, 18123-18128.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 18123-18128
    • Li, J.J.1
  • 18
    • 33644863026 scopus 로고    scopus 로고
    • Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats
    • Weroha,S.J. et al. (2006) Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats. Carcinogenesis, 27, 491-498.
    • (2006) Carcinogenesis , vol.27 , pp. 491-498
    • Weroha, S.J.1
  • 19
    • 51549099366 scopus 로고    scopus 로고
    • Estrogen-induced breast cancer: Alterations in breast morphology and oxidative stress as a function of estrogen exposure
    • Mense,S. et al. (2008) Estrogen-induced breast cancer: Alterations in breast morphology and oxidative stress as a function of estrogen exposure. Toxicol. Appl. Pharmacol., 232, 78-85.
    • (2008) Toxicol. Appl. Pharmacol , vol.232 , pp. 78-85
    • Mense, S.1
  • 20
    • 0028234634 scopus 로고
    • DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: Hormone-induced free radical damage preceding renal malignancy
    • Han,X. et al. (1994) DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: Hormone-induced free radical damage preceding renal malignancy. Carcinogenesis, 15, 997-1000.
    • (1994) Carcinogenesis , vol.15 , pp. 997-1000
    • Han, X.1
  • 21
    • 0029086898 scopus 로고
    • Induction by estrogens of lipid peroxidation and lipid peroxide-derived malonaldehyde-DNA adducts in male Syrian hamsters: Role of lipid peroxidation in estrogen-induced kidney carcinogenesis
    • Wang,M.Y. et al. (1995) Induction by estrogens of lipid peroxidation and lipid peroxide-derived malonaldehyde-DNA adducts in male Syrian hamsters: Role of lipid peroxidation in estrogen-induced kidney carcinogenesis. Carcinogenesis, 16, 1941-1945.
    • (1995) Carcinogenesis , vol.16 , pp. 1941-1945
    • Wang, M.Y.1
  • 22
    • 0024710646 scopus 로고
    • Comparison of assays for catechol estrogen synthase activity: Product isolation vs radioenzymatic catechol-O-methyltransferase-coupled procedures
    • Roy,D. et al. (1989) Comparison of assays for catechol estrogen synthase activity: Product isolation vs radioenzymatic catechol-O-methyltransferase-coupled procedures. J. Steroid Biochem. 33, 243-249.
    • (1989) J. Steroid Biochem , vol.33 , pp. 243-249
    • Roy, D.1
  • 23
    • 0028077519 scopus 로고
    • Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: Implications for the mechanism of estrogen-induced carcinogenesis
    • Zhu,B.T. et al. (1994) Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: Implications for the mechanism of estrogen-induced carcinogenesis. Endocrinology 135, 1772-1779.
    • (1994) Endocrinology , vol.135 , pp. 1772-1779
    • Zhu, B.T.1
  • 24
    • 0017326501 scopus 로고
    • NADPH-cytochrome P-450 reductase from rat liver: Purification by affinity chromatography and characterization
    • Dignam,J.D. et al. (1977) NADPH-cytochrome P-450 reductase from rat liver: Purification by affinity chromatography and characterization. Biochemistry, 16, 1116-1123.
    • (1977) Biochemistry , vol.16 , pp. 1116-1123
    • Dignam, J.D.1
  • 25
    • 0031694273 scopus 로고    scopus 로고
    • Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1
    • Shimada,T. et al. (1998) Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1. Chem. Res. Toxicol., 11, 1048-1056.
    • (1998) Chem. Res. Toxicol , vol.11 , pp. 1048-1056
    • Shimada, T.1
  • 26
    • 0037292971 scopus 로고    scopus 로고
    • Cytochrome P450 1B1: A target for inhibition in anticarcinogenesis strategies
    • Guengerich,F.P. et al. (2003) Cytochrome P450 1B1: A target for inhibition in anticarcinogenesis strategies. Mutat. Res., 523-524, 173-182.
    • (2003) Mutat. Res , vol.523-524 , pp. 173-182
    • Guengerich, F.P.1
  • 27
    • 0025817552 scopus 로고
    • DNA adduct formation in liver and kidney of male Syrian hamsters treated with estrogen and/or alpha-naphthoflavone
    • Liehr,J.G. et al. (1991) DNA adduct formation in liver and kidney of male Syrian hamsters treated with estrogen and/or alpha-naphthoflavone. Carcinogenesis, 12, 385-389.
    • (1991) Carcinogenesis , vol.12 , pp. 385-389
    • Liehr, J.G.1
  • 28
    • 0021175857 scopus 로고
    • High incidence of hepatocellular carcinomas after synthetic estrogen administration in Syrian golden hamsters fed alpha-naphthoflavone: A new tumor model
    • Li,J.J. et al. (1984) High incidence of hepatocellular carcinomas after synthetic estrogen administration in Syrian golden hamsters fed alpha-naphthoflavone: A new tumor model. J. Natl Cancer Inst., 73, 543-547.
    • (1984) J. Natl Cancer Inst , vol.73 , pp. 543-547
    • Li, J.J.1
  • 29
    • 34347251604 scopus 로고    scopus 로고
    • Quantification of F2-isoprostanes as a biomarker of oxidative stress
    • Milne,G.L. et al. (2007) Quantification of F2-isoprostanes as a biomarker of oxidative stress. Nat. Protoc., 2, 221-226.
    • (2007) Nat. Protoc , vol.2 , pp. 221-226
    • Milne, G.L.1
  • 30
    • 33746847720 scopus 로고    scopus 로고
    • Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention
    • Cavalieri,E. et al. (2006) Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention. Biochim. Biophys. Acta, 1766, 63-78.
    • (2006) Biochim. Biophys. Acta , vol.1766 , pp. 63-78
    • Cavalieri, E.1
  • 31
    • 0036793920 scopus 로고    scopus 로고
    • Tissue content of hydroxyestrogens in relation to survival of breast cancer patients
    • Castagnetta,L.A. et al. (2002) Tissue content of hydroxyestrogens in relation to survival of breast cancer patients. Clin. Cancer Res. 8, 3146-3155.
    • (2002) Clin. Cancer Res , vol.8 , pp. 3146-3155
    • Castagnetta, L.A.1
  • 32
    • 0023181602 scopus 로고
    • Estrogen carcinogenesis in Syrian hamster tissues: Role of metabolism
    • Li,J.J. et al. (1987) Estrogen carcinogenesis in Syrian hamster tissues: Role of metabolism. Fed. Proc., 46, 1858-1863.
    • (1987) Fed. Proc , vol.46 , pp. 1858-1863
    • Li, J.J.1
  • 33
    • 0034650264 scopus 로고    scopus 로고
    • Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens
    • Newbold,R.R. et al. (2000) Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens. Cancer Res., 60, 235-237.
    • (2000) Cancer Res , vol.60 , pp. 235-237
    • Newbold, R.R.1
  • 34
    • 1942497956 scopus 로고    scopus 로고
    • Cytochromes P450, drugs, and diseases
    • Guengerich,F.P. (2003) Cytochromes P450, drugs, and diseases. Mol. Interv., 3, 194-204.
    • (2003) Mol. Interv , vol.3 , pp. 194-204
    • Guengerich, F.P.1
  • 35
    • 0021934592 scopus 로고
    • Estrogen 2- and 4-hydroxylase activity, catechol estrogen formation, and implications for estrogen carcinogenesis in the hamster kidney
    • Li,S.A. et al. (1985) Estrogen 2- and 4-hydroxylase activity, catechol estrogen formation, and implications for estrogen carcinogenesis in the hamster kidney. Cancer Res., 45, 181-185.
    • (1985) Cancer Res , vol.45 , pp. 181-185
    • Li, S.A.1
  • 36
    • 47049114843 scopus 로고    scopus 로고
    • Human biochemistry of the isoprostane pathway
    • Milne,G.L. et al. (2008) Human biochemistry of the isoprostane pathway. J. Biol. Chem., 283, 15533-15537.
    • (2008) J. Biol. Chem , vol.283 , pp. 15533-15537
    • Milne, G.L.1
  • 37
    • 0030960296 scopus 로고    scopus 로고
    • Dual role of oestrogens as hormones and pro-carcinogens: Tumour initiation by metabolic activation of oestrogens
    • Liehr,J.G. (1997) Dual role of oestrogens as hormones and pro-carcinogens: Tumour initiation by metabolic activation of oestrogens. Eur. J. Cancer Prev., 6, 3-10.
    • (1997) Eur. J. Cancer Prev , vol.6 , pp. 3-10
    • Liehr, J.G.1
  • 38
    • 0033015707 scopus 로고    scopus 로고
    • 4-hydroxylation of oestrogens as a marker for mammary tumours
    • Liehr,J.G. (1999) 4-hydroxylation of oestrogens as a marker for mammary tumours. Biochem. Soc. Trans., 27, 318-323.
    • (1999) Biochem. Soc. Trans , vol.27 , pp. 318-323
    • Liehr, J.G.1
  • 39
    • 0019722348 scopus 로고
    • Changes in estrogen receptor levels during DES-induced hepatocarcinogenesis in the Syrian hamster fed alpha-naphthoflavone
    • Li,S.A. et al. (1981) Changes in estrogen receptor levels during DES-induced hepatocarcinogenesis in the Syrian hamster fed alpha-naphthoflavone. J Steroid Biochem., 15, 387-392.
    • (1981) J Steroid Biochem , vol.15 , pp. 387-392
    • Li, S.A.1
  • 40
    • 0029865150 scopus 로고    scopus 로고
    • 4-Hydroxylation of estrogens as marker of human mammary tumors
    • Liehr,J.G. et al. (1996) 4-Hydroxylation of estrogens as marker of human mammary tumors. Proc. Natl Acad. Sci. USA, 93, 3294-3296.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 3294-3296
    • Liehr, J.G.1
  • 41
    • 0038393297 scopus 로고    scopus 로고
    • Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: Potential biomarkers of susceptibility to cancer
    • Rogan,E.G. et al. (2003) Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer. Carcinogenesis, 24, 697-702.
    • (2003) Carcinogenesis , vol.24 , pp. 697-702
    • Rogan, E.G.1
  • 42
    • 19944428679 scopus 로고    scopus 로고
    • The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone
    • Turan,V.K. et al. (2004) The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone. J. Endocrinol., 183, 91-99.
    • (2004) J. Endocrinol , vol.183 , pp. 91-99
    • Turan, V.K.1
  • 43
    • 0025209997 scopus 로고
    • Dietary factors and risk of breast cancer: Combined analysis of 12 case-control studies
    • Howe,G.R. et al. (1990) Dietary factors and risk of breast cancer: combined analysis of 12 case-control studies. J. Natl Cancer Inst. 82, 561-569.
    • (1990) J. Natl Cancer Inst , vol.82 , pp. 561-569
    • Howe, G.R.1
  • 44
    • 0027260836 scopus 로고
    • Antioxidant micronutrients and breast cancer
    • Garland,M. et al. (1993) Antioxidant micronutrients and breast cancer. J. Am. Coll. Nutr., 12, 400-411.
    • (1993) J. Am. Coll. Nutr , vol.12 , pp. 400-411
    • Garland, M.1
  • 45
    • 0027258857 scopus 로고
    • A prospective study of the intake of vitamins C, E, and A and the risk of breast cancer
    • Hunter,D.J. et al. (1993) A prospective study of the intake of vitamins C, E, and A and the risk of breast cancer. N. Engl. J. Med. 329, 234-240.
    • (1993) N. Engl. J. Med , vol.329 , pp. 234-240
    • Hunter, D.J.1
  • 46
    • 0030018520 scopus 로고    scopus 로고
    • Intake of vitamins A, C, and E and postmenopausal breast cancer. The Iowa Women's Health Study
    • Kushi,L.H. et al. (1996) Intake of vitamins A, C, and E and postmenopausal breast cancer. The Iowa Women's Health Study. Am. J. Epidemiol., 144, 165-174.
    • (1996) Am. J. Epidemiol , vol.144 , pp. 165-174
    • Kushi, L.H.1
  • 47
    • 0027419906 scopus 로고
    • Dietary fiber, vitamins A, C, and E, and risk of breast cancer: A cohort study
    • Rohan,T.E. et al. (1993) Dietary fiber, vitamins A, C, and E, and risk of breast cancer: A cohort study. Cancer Causes Control, 4 29-37.
    • (1993) Cancer Causes Control , vol.4 , pp. 29-37
    • Rohan, T.E.1
  • 48
    • 0031030604 scopus 로고    scopus 로고
    • Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: A prospective cohort study
    • Verhoeven,D.T. et al. (1997) Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: A prospective cohort study. Br. J. Cancer, 75, 149-155.
    • (1997) Br. J. Cancer , vol.75 , pp. 149-155
    • Verhoeven, D.T.1
  • 49
    • 0033577234 scopus 로고    scopus 로고
    • Dietary carotenoids and vitamins A, C, and E and risk of breast cancer
    • Zhang,S. et al. (1999) Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J. Natl Cancer Inst., 91, 547-556.
    • (1999) J. Natl Cancer Inst , vol.91 , pp. 547-556
    • Zhang, S.1
  • 50
    • 0035865964 scopus 로고    scopus 로고
    • Dietary antioxidant vitamins, retinol, and breast cancer incidence in a cohort of Swedish women
    • Michels,K.B. et al. (2001) Dietary antioxidant vitamins, retinol, and breast cancer incidence in a cohort of Swedish women. Int. J. Cancer, 91, 563-567.
    • (2001) Int. J. Cancer , vol.91 , pp. 563-567
    • Michels, K.B.1


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