Interaction of antigens and antibodies at mucosal surfaces

Annual Review of Microbiology

Volumn 51, Issue , 1997, Pages 311-340

  Lamm, Michael E ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Disposition of antigens; IgA; Immune barrier; Immune defense; Infections

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN RECEPTOR;

ANTIBACTERIAL ACTIVITY; ANTIGEN ANTIBODY REACTION; BACTERIUM ADHERENCE; HUMAN; IMMUNOGLOBULIN PRODUCTION; INFECTION; INFLAMMATION; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; VIRUS NEUTRALIZATION;

ANTIBODIES, BLOCKING; ANTIGEN-ANTIBODY REACTIONS; COMPLEMENT PATHWAY, CLASSICAL; ENDOPEPTIDASES; EPITHELIUM; HUMANS; IGA DEFICIENCY; IMMUNITY, MUCOSAL; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULINS; INFLAMMATION; PLASMA CELLS; VACCINATION; VIRUS DISEASES;

BACTERIA (MICROORGANISMS); PHASEOLUS (ANGIOSPERM);

EID: 0030861590     PISSN: 00664227     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.micro.51.1.311     Document Type: Review

References (163)

1. Abraham SN, Beachey EH. 1985. Host defenses against adhesion of bacteria to mucosal surfaces. In Advances in Host Defense Mechanisms, ed. JF Gallin, AS Fauci, 4:63-88. New York: Raven
2. Abu-Ghazaleh RI, Fujisawa T, Mestecky J, Kyle RA, Gleich GJ. 1989. IgA-induced eosinophil degranulation. J. Immunol. 142:2393-400
3. Åkerström B, Lindqvist A, Vander Maelen C, Grubb A, Lindahl G, Vaerman J-P. 1994. Interaction between streptococcal protein ARP and different molecular forms of human immunoglobulin A. Molec. Immunol. 31:393-400
4. Apodaca G, Katz L, Mostov KE. 1994. Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. J. Cell Biol. 125:67-86
5. Apter FM, Michetti P, Winner LS III, Mack JA, Mekalanos JJ, Neutra MR. 1993. Analysis of the roles of antipolysaccharide and anti-cholera toxin immunoglobulin A (IgA) antibodies in protection against Vibrio cholerae and cholera toxin by use of monoclonal IgA antibodies in vivo. Infect. Immun. 61:5279-85
6. Armstrong SJ, Dimmock NJ. 1992. Neutralization of influenza virus by low concentrations of hemaglutinin-specific polymeric immunoglobulin A inhibits viral fusion activity, but activation of the ribonucleoprotein is also inhibited. J. Virol. 66:3823-32
7. Bender BS, Rowe CA, Taylor SF, Wyatt LS, Moss B, Small PA Jr. 1996. Oral immunization with a replication-deficient recombinant vaccinia virus protects mice against influenza. J. Virol. 70:6418-24
8. Bessen D, Fischetti VA. 1988. Passive acquired mucosal immunity to group A streptococci by secretory immunoglobulin A. J. Exp. Med. 167:1945-50
9. Blanchard TG, Czinn SJ, Maurer R, Thomas WD, Soman G, Nedrud JG. 1995. Urease-specific monoclonal antibodies prevent Helicobacter felis infection in mice. Infect. Immun. 63:1394-99
10. Brandtzaeg P. 1995. Molecular and cellular aspects of the secretory immunoglobulin system. Acta Path. Microbiol. Immunol. Scand. 103:1-19
11. Brandtzaeg P, Karlsson G, Hansson G, Petruson B, Björkander J, Hanson LA. 1987. The clinical condition of IgA-deficient patients is related to the proportion of IgD- and IgM-producing cells in their nasal mucosa. Clin. Exp. Immunol. 67:626-36
12. Brown WR, Newcomb RW, Ishizaka K. 1970. Proteolytic degradation of exocrine and serum immunoglobulins. J. Clin. Invest. 49:1374-80
13. Bums JW, Siadat-Pajouh M, Krishnaney AA, Greenberg HB. 1996. Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity. Science 272:104-7
14. Burton DR, Barbas CF. 1994. Human antibodies from combinatorial libraries. Adv. Immunol. 57:191-280
15. Capron M, Capron A. 1994. Immunoglobulin E and effector cells in schistosomiasis. Science 264:1876-77
16. Carayannopoulos L, Max EE, Capra JD. 1994. Recombinant human IgA expressed in insect cells. Proc. Natl. Acad. Sci. USA 91:8348-52
17. Cardenas L, Clements JD. 1992. Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens. Clin. Microbiol. Rev. 5:328-42
18. Casadevall A, Scharff MD. 1995. Return to the past: the case for antibody-based therapies in infectious diseases. Clin. Infect. Dis. 21:150-61
19. Castrignano SB, Carlsson B, Carneiro-Sampaio MS, Söderström T, Hanson LA. 1993. IgA and IgG subclass deficiency in a poor population in a developing country. Scand. J. Immunol. 37:509-14
20. Chanock RM, Crowe JE Jr, Murphy BR, Burton DR. 1993. Human monoclonal antibody Fab fragments cloned from combinatorial libraries: potential usefulness in prevention and/or treatment of major human viral diseases. Infect. Agents Dis. 2:118-31
21. Chen KS, Quinnan GV Jr. 1989. Efficacy of inactivated influenza vaccine delivered by oral administration. Curr. Top. Microbiol. Immunol. 146:101-6
22. Chintalacharuvu KR, Tavill AS, Louis LN, Vaerman J-P, Lamm ME, Kaetzel CS. 1994. Disulfide bond formation between dimertc immunoglobulin A and the polymeric immunoglobulin receptor during hepatic transcytosis. Hepatology 19:162-73
23. Clements ML, Betts RF, Tierney EL, Murphy BR. 1986. Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus. J. Clin. Microbiol. 24: 157-60
24. Cone RA, Whaley KJ. 1994. Monoclonal antibodies for reproductive health: Part I. Preventing sexual transmission of disease and pregnancy with topically applied antibodies. Am. J. Reprod. Immunol. 32:114-31
25. Cotter TW, Meng Q, Shen Z-L, Zhang Y-X, Su H, Caldwell HD. 1995. Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection. Infect. Immun. 63:4704-14
26. Craig SW, Cebra JJ. 1975. Rabbit Peyer's patches, appendix, and popliteal lymph nodeB-lymphocytes: a comparative analysis of their membrane immunoglobulin components and plasma cell precursor potential. J. Immunol. 114:492-502
27. Cripps AW, Dunkley ML, Clancy RL. 1994. Mucosal and systemic immunizations with killed Pseudomonas aeruginosa protect against acute respiratory infection in rats. Infect. Immun. 62:1427-36
28. Crowe JE, Murphy BR, Chanock RM, Williamson RA, Barbas CF III, Burton DR. 1994. Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice. Proc. Natl. Acad. Sci. USA 91:1386-90
29. Cruz JR, Gil L, Cano P, Caceres P, Pareja G. 1988. Breastmilk anti-Escherichia coli heat-labile toxin IgA antibodies protect against toxin-induced infantile diarrhea. Acta Paediatr. Scand. 77:658-62
30. Cunningham-Rundles C, Brandeis WE, Good RA, Day NK. 1979. Bovine antigens and the formation of circulating immune complexes in selective immunoglobulin A deficiency. J. Clin. Invest. 64:272-79
31. Curtis GH, Gall DG. 1992. Macromolecular transport by rat gastric mucosa. Am. J. Physiol. 262-G1033-40
32. Curtiss R III, Kelly SM, Gulig PA, Nakayama K. 1989. Selective delivery of antigens by recombinant bacteria. Curr. Top. Microbiol. Immunol. 146:35-49
33. Czerkinsky C, Prince SJ, Michalek SM, Jackson S, Russell MW, et al. 1987. IgA antibody producing cells in peripheral blood after antigen ingestion: evidence for a common mucosal immune system in humans. Proc. Natl. Acad. Sci. USA 84:2449-53
34. Czerkinsky C, Svennerholm A-M, Quiding M, Jonsson R, Holmgren J. 1991. Antibody-producing cells in peripheral blood and salivary glands after oral cholera vaccination of humans. Infect. Immun. 59:996-1001
35. Czinn SJ, Cai A, Nedrud JG. 1993. Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization. Vaccine 11:637-42
36. Davis NL, Brown KW, Johnston RE. 1996. A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge. J. Virol. 70:3781-87
37. Daynes RA, Enioutina EY, Butler S, Mu H-H, McGee ZA, Araneo BA. 1996. Induction of common mucosal immunity by hormonally immunomodulated peripheral immunization. Infect. Immun. 64:1100-9
38. Defrance T, Vanbervliet B, Briere F, Durand I, Roussel R, Banchereau J. 1992. Interleukin 10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J. Exp. Med. 175:671-82
39. Dickinson BL, Clements JD. 1995. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun. 63:1617-23
40. Di Tommaso A, Saletti G, Pizza M, Rappuoli R, Dougan G, et al. 1996. Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant. Infect. Immun. 64:974-79
41. Douce G, Trucotte C, Cropley I, Roberts M, Pizza M, et al. 1995. Mutants of Escherichia coli heat labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants. Proc. Natl. Acad. Sci. USA 92:1644-48
42. Eldridge JH, Staas JK, Meulbroek JA, McGhee JR, Tice TR, Gilley RM. 1991. Biodegradable microspheres as a vaccine delivery system. Mol. Immunol. 28:287-94
43. Feng N, Burns JW, Bracy L, Greenberg HB. 1994. Comparison of mucosal and systemic humoral immune responses and subsequent protection in mice orally inoculated with a homologous or a heterologous rotavirus. J. Virol. 68:7766-73
44. Frey A, Giannasca KT, Weltzin R, Giannasca PJ, Reggio H, et al. 1996. Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. J. Exp. Med. 184:1045-59
45. Fubara ES, Freter R. 1973. Protection against enteric bacterial infection by secretory IgA antibodies. J. Immunol. 111:395-403
46. Fujihashi K, Kweon M-N, Kiyono H, VanCott JL, van Ginkel F, et al. 1997. A T cell/B cell/epithelial cell internet for mucosal inflammation and immunity. Springer Sem. Immunopath. 18:477-94
47. Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL. 1993. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. USA 90:11478-82
48. Gerber JD, Ingersoll JD, Gast AM, Christianson KK, Setzer NL, et al. 1990. Protection against feline infectious peritonitis by intranasal inoculation of a temperature-sensitive FIPV vaccine. Vaccine 8:536-42
49. Gilbert JV, Plaut AG, Longmaid B, Lamm ME. 1983. Inhibition of microbial IgA proteases by human secretory IgA and serum. Molec. Immunol. 20:1039-49
50. Glass RE, Svennerholm AM, Stoll BJ, Khan MR, Hossein KMB, et al. 1983. Protection against cholera in breast-fed children by antibodies in breast-milk. N. Engl. J. Med. 308:1389-92
51. Guarino A, Canani RB, Russo S, Albano F, Canani MB, et al. 1994. Oral immunoglobulins for treatment of acute rotaviral gastroenteritis. Pediatrics 93:12-16
52. Guzman CA, Molinari G, Fountain MW, Rohde M, Timmis KN, Walker MJ. 1993. Antibody responses in the serum and respiratory tract of mice following oral vaccination with liposomes coated with filamentous hemagglutinin and pertussis toxoid. Infect. Immun. 61:573-79
53. Hajishengallis G, Nikolova E, Russell MW. 1992. Inhibition of Streptococcus mutatis adherence to saliva-coated hydroxyapatite by human secretory immunoglobulin A antibodies to the cell surface protein antigen I/II: reversal by IgA1 protease cleavage. Infect. Immun. 60:5057-64
54. Haneberg B, Kendall D, Amerongen HM, Apter FM, Kraehenbuhl J-P, Neutra MR. 1994. Induction of specific immunoglobulin A in the small intestine, colon-rectum, and vagina measured by a new method for collection of secretions from local mucosal surfaces. Infect. Immun. 62:15-23
55. Hanson LA, Björkander J, Carlsson B, Roberton D, Söderström T. 1988. The heterogeneity of IgA deficiency. J. Clin. Immunol. 8:159-62
56. Holmgren J, Lycke N, Czerkinsky C. 1993. Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. Vaccine 11:1179-84
57. Hopkins S, Kraehenbuhl J-P, Schodel F, Potts A, Peterson D, et al. 1995. A recombinant Salmonella typhimurium vaccine induces local immunity by four different routes of immunization. Infect. Immun. 63:3279-86
58. Husband AJ, Gowans JL. 1978. The origin and antigen-dependent distribution of IgA-containing cells in the intestine. J. Exp. Med. 148.1146-60
59. Husby S, Jensenius JC, Svehag SE. 1985. Passage of undegraded dietary antigen into the blood of healthy adults: quantitation, estimation of size distribution, and relation of uptake to levels of specific antibodies. Scand J. Immunol. 22:83-92
60. Jagusztyn-Krynicka EK, Clark-Curtiss JE, Curtiss III R. 1993. Escherichia coli heat-labile toxin subunit B fusions with Streptococcus sobrinus antigens expressed by Salmonella typhimurium oral vaccine strains: importance of the linker for antigenicity and biological activities of the hybrid proteins. Infect. Immun. 61:1004-15
61. Jarvis GA, Griffiss JM. 1991. IgA1 blockade of IgG-initiated lysis of Neisseria meningitidis is a function of antigen-binding fragment binding to the polysaccharide capsule. J. Immunol. 147:1962-67
62. Jertborn M, Svennerholm AM, Holmgren J. 1986. Saliva, breast milk, and serum antibody responses as indirect measures of intestinal immunity after oral cholera vaccination or natural disease. J. Clin. Microbiol. 24:203-9
63. Johnson PR, Feldman S, Thompson JM, Mahoney JD, Wright P. 1986. Immunity to influenza A virus infection in young children: a comparison of natural infection, live cold-adapted vaccine, and inactivated vaccine. J. Infect. Dis. 154:121-27
64. Jones DH, McBride BW, Thornton C, O'Hagan DT, Robinson A, Farrar GH. 1996. Orally administered microencapsulated Bordelella pertussis fimbriae protect mice from B. pertussis respiratory infection. Infect. Immun. 64:489-94
65. Kaetzel CS, Robinson JK, Chintalacharuvu KR, Vaerman J-P, Lamm ME. 1991. The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: a local defense function of IgA. Prof. Natl. Acad. Sci. USA 88:8796-800
66. Kaetzel CS, Robinson JK, Lamm ME. 1994. Epithelial transcytosis of monomeric IgA and IgG cross-linked through antigen to polymeric IgA. A role for monomeric antibodies in the mucosal immune system. J. Immunol. 152:72-76
67. Kanesaki T, Murphy BR, Collins PL, Ogra PL. 1991. Effectiveness of enteric immunization in the development of secretory immunoglobulin A response and the outcome of infection with respiratory syncytial virus. J. Virol. 65:657-63
68. Keren DF, McDonald RA, Carey JL. 1988. Combined parenteral and oral immunization results in an enhanced mucosal immunoglobulin A response to Shigella flexneri. Infect. Immun. 56:910-15
69. Kerr MA. 1990. The structure and function of human IgA. Biochem. J. 271:285-96
70. Kerr MA, Mazengera RL, Stewart WW. 1990. Structure and function of immunoglobulin A receptors on phagocytic cells. Biochem. Soc. Trans. 18:215-17
71. Kilian M, Reinholdt J, Lomholt H, Poulsen K, Frandsen EVG. 1996. Biological significance of IgA I proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence. Acta Path. Microbiol. Immunol. Scand. 104:321-38
72. Kilian M, Russell MW. 1994. Function of mucosal immunoglobulins. In Handbook of Mucosal Immunology, ed. PL Ogra, J Mestecky, ME Lamm, W Strober, JR McGhee, J Bienenstock, pp. 127-37. San Diego: Academic
73. King CL, Nutman TB. 1993. Cytokines and immediate hypersensitivity in protective immunity to Helminth infections. In Infectious Agents and Disease, 2:103-8. New York: Raven
74. Kiyono H, Miller CJ, Lu Y, Lehner T, Cranage M, et al. 1995. The common mucosal immune system for the reproductive tract: basic principles applied toward an AIDS vaccine. Adv. Drug Delivery Rev. 18:23-51
75. Kraehenbuhl J-P, Neutra MR. 1992. Molecular and cellular basis of immune protection of mucosal surfaces. Physiol. Rev. 72:853-79
76. Kris RM, Asofsky R, Evans CB, Small PA Jr. 1985. Protection and recovery in influenza virus-infected mice immunosuppressed with anti-IgM. J. Immunol. 134:1230-35
77. Lee CK, Weltzin R, Soman G, Georgakopoulos KM, Houle DM, Monath TP. 1994. Oral administration of polymeric immunoglobulin A prevents colonization with Vibrio cholerae in neonatal mice. Infect. Immun. 62:887-91
78. Lehner T, Brookes R, Panagiotidi C, Tao L, Klavinskis LS, et al. 1993. T- and B-cell functions and epitope expression in non-human primates immunized with simian immunodeficiency virus antigen by the rectal route. Proc. Natl. Acad. Sci. USA 90:8638-42
79. Lehner T, Tao L, Panagiotidi C, Klavinskis LS, Brookes R, et al. 1994. Mucosal model of genital immunization in male rhesus macaques with a recombinant simian immunodeficiency virus p27 antigen. J. Virol. 68:1624-32
80. Liew FY, Russell SM, Appleyard G, Brand CM, Beale J. 1984. Cross protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA rather than serum antibody or cytotoxic T cell reactivity. Eur. J. Immunol. 14:350-56
81. Lindahl G, Akerström B, Frithz E, Hedén L-O, Stenberg L. 1990. Protein Arp, the immunoglobulin A receptor of group A streptococci. In Bacterial Immunoglobulin-Binding Proteins. Microbiology, Chemistry, and Biology, ed. MDP Boyle, 1:193-200. San Diego: Academic
82. Lindh E. 1975. Increased resistance of immunoglobulin A dimers to proteolytic degradation after binding of secretory component. J. Immunol. 14:284-86
83. Lycke N, Tsuji T, Holmgren J. 1992. The adjuvant effect of Vibrio cholerae and E. coli heat labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur. J. Immunol. 22:2277-81
84. Ma JK-C, Hiatt A, Hein M, Vine ND, Wang F, et al. 1995. Generation and assembly of secretory antibodies in plants. Science 268:716-19
85. Ma JK-C, Hunjan M, Smith R, Kelly C, Lehner T. 1990. An investigation into the mechanism of protection by local passive immunization with monoclonal antibodies against Streptococcus mutant. Infect. Immun. 58:3407-14
86. Maizels RM, Bundy DAP, Selkirk ME, Smith DF, Anderson RM. 1993. Immunological modulation and evasion by helminth parasites in human populations. Nature 365:797-805
87. Mason HS, Lam DM-K, Arntzen CJ. 1992. Expression of hepatitis B surface antigen in transgenic plants. Proc. Natl. Acad. Sci. USA 89:11745-49
88. Mazanec MB, Coudret CL, Fletcher DR, 1995. Intracellular neutralization of influenza virus by IgA anti-HA monoclonal antibodies. J. Virol. 69:1339-43
89. Mazanec MB, Kaetzel CS, Lamm ME, Fletcher D, Nedrud JG. 1992. Intracellular neutralization of virus by immunoglobulin A antibodies. Proc. Natl. Acad. Sci. USA 89:6901-05
90. Mazanec MB, Lamm ME, Lyn D, Portner A, Nedrud JG. 1992. Comparison of IgA versus IgG monoclonal antibodies for passive immunization of the murine respiratory tract. Virus. Res. 23:1-12
91. Mazanec MB, Nedrud JG, Lamm ME. 1987. Immunoglobulin A monoclonal antibodies protect against Sendai virus. J. Virol. 61:2624-26
92. Mazengera RL, Kerr MA. 1990. The specificity of the IgA receptor purified from human neutrophils. Biochem. J. 272:159-65
93. McCormick BA, Stocker BAD, Laux DC, Cohen PS. 1988. Roles of motility, chemotaxis and penetration through and growth in intestinal mucus in the ability of a virulent strain of S. typhimurium to colonize the large intestine of the streptomycin-treated mouse. Infect. Immun. 50:2209-17
94. McDermott MR, Bienenstock J. 1979. Evidence for a common mucosal immunologie system. I. Migration of B immunoblasts into intestinal, respiratory and genital tissues. J. Immunol. 122:1892-98
95. McGhee JR, Mestecky J. 1990. In defense of mucosal surfaces. Infect. Dis. Clin. N. Am. 4:315-41
96. McGhee JR, Mestecky J, Dertzbaugh MT, Eldridge JH, Hirasawa M, Kiyono H. 1992. The mucosal immune system: from fundamental concepts to vaccine development. Vaccine 10:75-88
97. Mellander L, Björkander J, Carlsson B, Hanson LA. 1986. Secretory antibodies in IgA deficient and immunosuppressed individuals. J. Clin. Immunol. 6:284-91
98. Mestecky J, Moldoveanu Z, Novak M, Huang W-Q, Gilley RM, et al. 1994. Biodegradable microspheres for the delivery of oral vaccines. J. Control. Rel. 28:131-41
99. Michalek SM, McGhee JR, Babb JL. 1978. Effective immunity to dental caries: dose-dependent studies of secretory immunity by oral administration of Streptococcus mutans to rats. Infect. Immun. 19:217-24
100. Michetti P, Mahan MJ, Slauch JM, Mekalanos JJ, Neutra MR. 1992. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium. Infect. Immun. 60:1786-92
101. α receptors detected by receptor-specific monoclonal antibodies. J. Immunol. 148:1764-70
102. Monteiro RC, Hostoffer RW, Cooper MD, Bonner JR, Gartland GL, Kubagawa H. 1993. Definition of IgA receptors on eosinophils and their enhanced expression in allergic individuals. J. Clin. Invest. 92:1681-85
103. Mostov KE. 1994. Transepithelial transport of immunoglobulins. Annu. Rev. Immunol. 12:63-84
104. Mostov KE, Deitcher DL. 1986. Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA. Cell 46:613-21
105. Muster T, Ferko B, Klima A, Purtscher M, Trkola A, et al. 1995. Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virus. J. Virol. 69:6678-86
106. Nedrud JG, Liang X, Hague N, Lamm ME. 1987. Combined oral/nasal immunization protects mice from Sendai virus infection. J. Immunol. 139:3484-92
107. Negrão-Corrêa D, Adams LS, Bell RG. 1996. Intestinal transport and catabolism of IgE. A major blood-independent pathway of IgE dissemination during a Trichinella spiralis infection of rats. J. Immunol. 157:4037-44
108. Neutra MR, Frey A, Kraehenbuhl J-P. 1996. Epithelial M cells: gateways for mucosal infection and immunization. Cell 86:345-48
109. Neutra MR, Pringault E, Kraehenbuhl J-P. 1996. Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu. Rev. Immunol. 14:275-300
110. Nikolova EB, Tomana M, Russell MW. 1994. The role of the carbohydrate chains in complement (C3) fixation by solid-phase-bound human IgA. Immunology 82:321-27
111. Nikolova EB, Tomana M, Russell MW. 1994. All forms of human IgA antibodies bound to antigen interfere with complement (C3) fixation induced by IgG or by antigen alone. Scand. J. Immunol. 39: 275-80
112. Odorizzi G, Pearse A, Domingo D, Trowbridge IS, Hopkins CR. 1996. Apical and basolaleral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism. J. Cell Biol. 135:139-52
113. Offit PA, Clark HF. 1985. Protection against rotavirus-induced gastroenteritis in a murine model by passively acquired gastrointestinal but not circulating antibodies. J. Virol. 54:58-64
114. Ogra PL, Karzon DT, Righthand F, McGillivray M. 1968. Immunoglobulin response in serum and secretions after immunization with live and inactivated poliovaccine and natural infection. N. Engl. J. Med. 279:893-900
115. Ogra PL, Mestecky J, Lamm ME, Strober W, McGhee JR, Bienenstock J, eds. 1994. Handbook of Mucosal Immunology. San Diego: Academic. 766 pp.
116. O'Hagan DT, McGee JP, Holmgren J, Mowat AM, Donachie AM, et al. 1993. Biodegradable microparticles for oral immunization. Vaccine 11:149-54
117. Onorato IM, Modlin JF, McBean AM, Thomas ML, Losonsky GA, Bernier RH. 1991. Mucosal immunity induced by enhanced-potency inactivated and oral polio vaccines. J. Infect. Dis. 163:1-6
118. Outlaw MC, Dimmock NJ. 1990. Mechanisms of neutralization of influenza virus on mouse tracheal epithelial cells by mouse monoclonal polymeric IgA and polyclonal IgM directed against the viral haemagglutinin. J. Gen. Virol. 71:69-76
119. Outlaw MC, Dimmock NJ. 1991. Insights into neutralization of animal viruses gained from study of influenza virus. Epidemiol. Infect. 106:205-20
120. Owen RL. 1994. M cells: entryways of opportunity for enteropathogens. J. Exp. Med. 180:7-9
121. Owen RL, Ermak TH. 1992. Structural specializations for antigen uptake and processing in the digestive tract. Springer Semin. Immunopathol. 12:139-52
122. Paganelli R, Lennsky RJ, Atherton DS. 1981. Detection of specific antigen within circulating immune complexes. Validation of the assay and its application to food antigen-antibody complexes found in healthy and food-allergic subjects. Clin. Exp. Immunol. 46:44-53
123. Pfaffenbach G, Lamm ME, Gigli I. 1982. Activation of the guinea pig alternative complement pathway by mouse IgA immune complexes. J. Exp. Med. 155:231-47
124. Phalipon A, Kaufmann M, Michetti P, Cavaillon J-M, Huerre M, et al. 1995. Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis. J. Exp. Med. 182:769-78
125. Phillips-Quagliata JM, Lamm ME. 1994. Lymphocyte homing to mucosal effector sites. See Ref. 115, pp. 225-39
126. Plaut AG, Bachovchin WW. 1994. IgA-specific prolyl endopeptidases (serine-type). Methods Enzymol. 244:137-51
127. Flaut AG, Wright A. 1995. IgA-specific prolyl endopeptidases (metallo-type). Methods Enzymol. 248:634-42
128. Prince GA, Hemming VG, Horswood RL, Baron PA, Murphy BR, Chanock RM. 1990. Mechanism of antibody-mediated viral clearance in immunotherapy of respiratory syncytial virus infection of cotton rats. J. Virol. 64:3091-92
129. Renegar KB, Small PA Jr. 1991. Passive transfer of local immunity to influenza virus infection by IgA antibody. J. Immunol. 146:1972-78
130. Renegar KB, Small PA Jr. 1991. Immunoglobulin A mediation of murine nasal anti-influenza virus immunity. J. Virol. 65:2146-48
131. Reuman PD, Bernstein DI, Keely SP, Sherwood JR, Young EC, Schiff GM. 1990. Influenza-specific ELISA IgA and IgG predict severity of influenza disease in subjects pre-screened with hemagglutination inhibition. Antiviral Res. 13:103-10
132. Ruiz-Palacios GM, Calva JJ, Pickering LK. 1990. Protection of breastfed infants against Campylobacter diarrhoea by antibodies in human milk. J. Pediatr. 116:707-13
133. Russell MW, Moldoveanu Z, White PL, Sibert GJ, Mestecky J, Michalek SM. 1996. Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the cholera toxin B subunit. Infect. Immun. 64:1272-83
134. Sestini P, Nencioni L, Villa L, Boraschi D, Tagliabue A. 1988. IgA-driven antibacterial activity against Streptococcus pneumoniae by mouse lung lymphocytes. Am. Rev. Respir. Dis. 137:138-43
135. Shroff KE, Meslin K, Cebra JJ. 1995. Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect. Immun. 63:3904-13
136. Sixbey JW, Yao Q-Y. 1992. Immunoglobulin A-induced shift of Epstein-Barr virus tissue tropism. Science 255:1578-80
137. Smith CB, Bellami JA, Chanock RM. 1967. Immunoglobulins in serum and nasal secretions following infection with type 1 parainfluenza virus and injection of inactivated vaccines. J. Immunol. 99:133-41
138. Staats HF, Jackson RJ, Mahnaro M, Takahashi I, Kiyono H, McGhee JR. 1994. Mucosal immunity to infection with implications for vaccine development. Curr. Opin. Immunol. 6:572-83
139. Staats HF, Nichols WG, Palker TJ. 1996. Mucosal immunity to HIV-1. Systemic and vaginal antibody responses after intranasal immunization with the HIV-1 C4/V3 peptide T1SP10 MN(A). J. Immunol. 157:462-72
140. Stokes CR, Soothill JF, Turner MW. 1975. Immune exclusion is a function of IgA. Nature 255:745-46
141. Svanborg-Eden C, Svennerholm A-M. 1978. Secretory immunoglobulin A and G antibodies prevent adhesion of Escherichia coli to human urinary tract epithelial cells. Infect. Immun. 22:790-97
142. Tada T, Ishizaka K. 1970. Distribution of γE-forming cells in lymphoid tissues of the human and monkey. J. Immunol. 104:377-87
143. Tagliabue A, Nencioni L, Villa L, Keren DF, Lowell GH, Boraschi D. 1983. Antibody-dependent cell-mediated antibacterial activity of intestinal lymphocytes with secretory IgA. Nature 306:184-86
144. Takahashi I, Marinaro M, Kiyono H, Jackson RJ, Nakagawa I, et al. 1996. Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin. J. Infect. Dis. 173:627-35
145. Tamura S-I, Funato H, Hirabayashi Y, Kikuta K, Suzuki Y, et al. 1990. Functional role of respiratory tract haemagglutinin-specinc IgA antibodies in protection against influenza. Vaccine 8:479-85
146. Tamura S, Funato H, Hirabayashi Y, Suzuki Y, Nagamine T, et al. 1991. Cross-protection against influenza A virus infection by passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules. Eur. J. Immunol. 21:1337-44
147. Taylor HP, Dimmock NJ. 1985. Mechanism of neutralization of influenza virus by secretory IgA is different from that of monomeric IgA or IgG. J. Exp. Med. 161:198-209
148. Waldman RH, Bergmann KC, Stone J, Howard S, Chiodo V, et al. 1987. Age-dependent antibody response in mice and humans following oral influenza immunization. J. Clin. Immunol. 7:327-32
149. Walker RI. 1994. New strategies for using mucosal vaccination to achieve more effective immunization. Vaccine 12:387-400
150. Walker WA, Isselbacher KJ, Bloch, KJ. 1972. Intestinal uptake of macromolecules: effect of oral immunization. Science 177:608-10
151. Watt PJ, Robinson BS, Pringle CR, Tyrrell DAJ. 1990. Determinants of susceptibility to challenge and the antibody response of adult volunteers given experimental respiratory syncytial virus vaccines. Vaccine 8:231-36
152. Weiner HL, Friedman A, Miller A, Khoury SJ, Al-Sabbagh A, et al. 1993. Oral tolerance: immunological mechanisms and treatment of murine and human organ specific autoimmune diseases by oral administration of autoamigens. Annu. Rev. Immunol. 12:809-37
153. Weinstein PD, Cebra JJ. 1991. The preference for switching to IgA expression by Peyer's patch germinal center B cells is likely due to the intrinsic influence of their microenvironment. J. Immunol. 147:4126-35
154. Weisz-Carrington P, Roux ME, McWilliams M, Phillips-Quagliata JM, Lamm ME. 1979. Organ and isotype distribution of plasma cells producing specific antibody after oral immunization: evidence for a generalized secretory immune system. J. Immunol. 123:1705-8
155. Weltzin R, Hsu SA, Mittler ES, Georgakopoulos K, Monath TP. 1994. Intranasal monoclonal immunoglobulin A against respiratory syncytial virus protects against upper and lower respiratory tract infections in mice. Antimicrob. Agents Chemother. 38:2785-91
156. Weltzin R, Lucia-Jandris P, Michetti P, Fields BN, Kraehenbuhl J, Neutra MR. 1989. Binding and transepithelial transport of immunoglobulins by intestinal M cells: demonstration using monoclonal IgA antibodies against enteric viral proteins. J. Cell Biol. 108:1673-85
157. Weltzin R, Traina-Dorge V, Soike K, Zhang J-Y, Mack P, et al. 1996. Intranasal monoclonal IgA antibody to respiratory syncytial virus protects rhesus monkeys against upper and lower respiratory tract infection. J. Infect. Dis. 174:256-61
158. Williams RC. Gibbons RJ. 1972. Inhibition of bacterial adherence by secretory immunoglobulin A: a mechanism of antigen disposal. Science 177:697-99
159. Winner IH L, Mack J, Weltzin R, Mekalanos JJ, Kraehenbuhl J-P, Neutra M. 1991. New model for analysis of mucosal immunity: Intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection. Infect. Immun. 59:977-82
160. Winter G, Griffiths AD, Hawkins RE, Hoogenboom HR. 1994. Making antibodies by phage display technology. Annu. Rev. Immunol. 12:433-55
161. Wold A, Endo T, Kobata A, Mestecky S, Tomana JM, et al. 1990. Secretory immunoglobulin A carries oligosaccharide receptors for the E. coli type 1 fimbrial lectin. Infect. Immun. 58:3073-77
162. Wright A, Shin S-U, Morrison SL. 1992. Genetically engineered antibodies: progress and prospects. Crit. Rev. Immunol. 12:125-68
163. 2 fragments protect mice from vaginal transmission of HSV-2. Virology 225:213-15