PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: Correlation with peripheral nerve function

Free Radical Biology and Medicine

Volumn 50, Issue 10, 2011, Pages 1400-1409

  Lupachyk, Sergey ^a   Shevalye, Hanna ^a   Maksimchyk, Yury ^a   Drel, Viktor R ^a   Obrosova, Irina G ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

1,5 Isoquinolinediol; 4 Hydroxynonenal adduct; Free radicals; Peripheral diabetic neuropathy; Poly(ADP ribose) polymerase; Systemic oxidative stress

Indexed keywords

1,5 ISOQUINOLINEDIOL; 4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; ISOPROSTANE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; COMPLEX FORMATION; CONTROLLED STUDY; DIABETIC NEUROPATHY; DIABETIC PERIPHERAL NEUROPATHY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GLIA CELL; HYPOALGESIA; MALE; MOTOR NERVE CONDUCTION; NERVE CELL; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PERIKARYON; PERIPHERAL NERVE; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN LOCALIZATION; RAT; SCHWANN CELL; SENSORY NERVE CONDUCTION; SPINAL CORD; SPINAL GANGLION; STREPTOZOCIN DIABETES; TACTILE ALLODYNIA; TACTILE STIMULATION; THERMAL HYPOALGESIA; TISSUE LEVEL; TREATMENT DURATION; URINARY EXCRETION; URINE LEVEL;

ALDEHYDES; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; MALE; NERVE TISSUE; OXIDATIVE STRESS; PERIPHERAL NERVES; POLY(ADP-RIBOSE) POLYMERASES; QUINOLINES; RATS; RATS, WISTAR;

RATTUS;

EID: 79955479655     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.01.037     Document Type: Article

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