Pivotal role of receptor-interacting protein kinase 1 and mixed lineage kinase domain-like in neuronal cell death induced by the human neuroinvasive coronavirus OC43

Journal of Virology

Volumn 91, Issue 1, 2017, Pages

  Meessen Pinard, Mathieu ^a   Le Coupanec, Alain ^a   Desforges, Marc ^a   Talbot, Pierre J ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Coronavirus; Human coronavirus; Human coronavirus OC43; Necroptosis; Regulated cell death; RIP

Indexed keywords

MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; PROTEIN BAX; PROTEIN SERINE THREONINE KINASE; RECEPTOR INTERACTING PROTEIN KINASE 1; UNCLASSIFIED DRUG; BAX PROTEIN, MOUSE; CORONAVIRUS SPIKE GLYCOPROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MLKL PROTEIN, MOUSE; PROTEIN KINASE; RALBP1 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CORONAVIRUS INFECTION; EMBRYO; FEMALE; HUMAN; HUMAN CELL; HUMAN CORONAVIRUS OC43; MOUSE; NECROPTOSIS; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL DEATH; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; MAMMALIAN EMBRYO; METABOLISM; MORTALITY; MUTATION; NERVE CELL; PATHOGENICITY; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TUMOR CELL LINE; VIROLOGY; VIRULENCE;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CELL DEATH; CELL LINE; CELL LINE, TUMOR; CORONAVIRUS INFECTIONS; CORONAVIRUS OC43, HUMAN; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION; GTPASE-ACTIVATING PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICE, INBRED BALB C; MUTATION; NEURONS; PRIMARY CELL CULTURE; PROTEIN KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPIKE GLYCOPROTEIN, CORONAVIRUS; SURVIVAL ANALYSIS; VIRULENCE;

EID: 85008219890     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01513-16     Document Type: Article

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