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Volumn 73, Issue 6, 1999, Pages 5181-5185

Epstein-Barr virus encodes a novel homolog of the bcl-2 oncogene that inhibits apoptosis and associates with Bax and Bak

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2;

EID: 0033057256     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.6.5181-5185.1999     Document Type: Article
Times cited : (144)

References (44)
  • 5
    • 0030296315 scopus 로고    scopus 로고
    • African swine fever virus gene A179L, a viral homologue of bcl-2, protects cells from programmed cell death
    • Brun, A., C. Rivas, M. Esteban, J. Escribano, and C. Alonso. 1996. African swine fever virus gene A179L, a viral homologue of bcl-2, protects cells from programmed cell death. Virology 225:227-230.
    • (1996) Virology , vol.225 , pp. 227-230
    • Brun, A.1    Rivas, C.2    Esteban, M.3    Escribano, J.4    Alonso, C.5
  • 6
    • 0027236875 scopus 로고
    • Human immunodeficiency virus-associated systematic lymphomas may be subdivided into two main groups according to Epstein-Barr viral latent gene expression
    • Carbone, A., U. Tirelli, A. Golghini, R. Volpe, and M. Boicchi. 1993. Human immunodeficiency virus-associated systematic lymphomas may be subdivided into two main groups according to Epstein-Barr viral latent gene expression. J. Clin. Oncol. 11:1674-1681.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1674-1681
    • Carbone, A.1    Tirelli, U.2    Golghini, A.3    Volpe, R.4    Boicchi, M.5
  • 7
    • 0029944880 scopus 로고    scopus 로고
    • Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis
    • Castedo, M., T. Hirsch, S. A. Susin, N. Zamzami, P. Marchetti, A. Macho, and G. Kroemer. 1996. Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. J. Immunol. 157: 512-521.
    • (1996) J. Immunol. , vol.157 , pp. 512-521
    • Castedo, M.1    Hirsch, T.2    Susin, S.A.3    Zamzami, N.4    Marchetti, P.5    Macho, A.6    Kroemer, G.7
  • 9
    • 0031017578 scopus 로고    scopus 로고
    • A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak
    • Cheng, E., J. Nicholas, D. Bellows, G. Hayward, H. Guo, M. Reitz, and J. Hardwick. 1997. A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Proc. Natl. Acad. Sci. USA 94:690-694.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 690-694
    • Cheng, E.1    Nicholas, J.2    Bellows, D.3    Hayward, G.4    Guo, H.5    Reitz, M.6    Hardwick, J.7
  • 10
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. 1997. Caspases: the executioners of apoptosis. Biochem. J. 326: 1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.1
  • 11
    • 0000074594 scopus 로고
    • Epstein-Barr genome
    • G. Klein (ed.), Raven Press, Ltd., New York, N.Y.
    • Farrell, P. J. 1989. Epstein-Barr genome, p. 103-132. In G. Klein (ed.), Advances in viral oncology; tumorigenic DNA viruses, vol. 8. Raven Press, Ltd., New York, N.Y.
    • (1989) Advances in Viral Oncology; Tumorigenic DNA Viruses , vol.8 , pp. 103-132
    • Farrell, P.J.1
  • 13
    • 0027260656 scopus 로고
    • Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death
    • Henderson, S., D. Huen, M. Rowe, C. Dawson, G. Johnson, and A. Rickinson. 1993. Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. Proc. Natl. Acad. Sci. USA 90:8479-8483.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8479-8483
    • Henderson, S.1    Huen, D.2    Rowe, M.3    Dawson, C.4    Johnson, G.5    Rickinson, A.6
  • 14
    • 0025772343 scopus 로고
    • Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
    • Henderson, S., M. Rowe, C. Gregory, D. Croom-Carter, F. Wang, R. Longnecker, E. Kieff, and A. Rickinson. 1991. Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65:1107-1115.
    • (1991) Cell , vol.65 , pp. 1107-1115
    • Henderson, S.1    Rowe, M.2    Gregory, C.3    Croom-Carter, D.4    Wang, F.5    Longnecker, R.6    Kieff, E.7    Rickinson, A.8
  • 15
    • 0028291141 scopus 로고
    • Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in bcl-2
    • Hengartner, M., and H. Horvitz. 1994. Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in bcl-2. Nature 369:318-320.
    • (1994) Nature , vol.369 , pp. 318-320
    • Hengartner, M.1    Horvitz, H.2
  • 16
    • 0028328850 scopus 로고
    • Interaction of ionizing radiation with the topoisomerase I poison Camptothecin in growing V-79 and HeLa cells
    • Hennequin, C., N. Giocanti, J. Balosso, and V. Favaudon. 1994. Interaction of ionizing radiation with the topoisomerase I poison Camptothecin in growing V-79 and HeLa cells. Cancer Res. 54:1720-1728.
    • (1994) Cancer Res. , vol.54 , pp. 1720-1728
    • Hennequin, C.1    Giocanti, N.2    Balosso, J.3    Favaudon, V.4
  • 17
    • 0028175963 scopus 로고
    • The apoptotic suppressor p35 is required early during baculovirus replication and is targeted to the cytosol of infected cells
    • Hershberger, P., D. LaCount, and P. Friesen. 1994. The apoptotic suppressor p35 is required early during baculovirus replication and is targeted to the cytosol of infected cells. J. Virol. 68:3467-3477.
    • (1994) J. Virol. , vol.68 , pp. 3467-3477
    • Hershberger, P.1    LaCount, D.2    Friesen, P.3
  • 18
    • 0028833859 scopus 로고
    • bcl-2 Deficiency in mice leads to pleiotropic abnormalities: Accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine
    • Kamada, S., A. Shimono, Y. Shinto, T. Tsujimura, T. Takahashi, T. Noda, Y. Kitamura, H. Kondoh, and Y. Tsujimoto. 1995. bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. Cancer Res. 55:354-359.
    • (1995) Cancer Res. , vol.55 , pp. 354-359
    • Kamada, S.1    Shimono, A.2    Shinto, Y.3    Tsujimura, T.4    Takahashi, T.5    Noda, T.6    Kitamura, Y.7    Kondoh, H.8    Tsujimoto, Y.9
  • 19
    • 0028859541 scopus 로고
    • Bax-deficient mice with lymphoid hyperplasia and male germ cell death
    • Knudson, C., K. Tung, W. Tourtellolte, G. Brown, and S. J. Korsmeyer. 1995. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 270:96-99.
    • (1995) Science , vol.270 , pp. 96-99
    • Knudson, C.1    Tung, K.2    Tourtellolte, W.3    Brown, G.4    Korsmeyer, S.J.5
  • 20
    • 0031660978 scopus 로고    scopus 로고
    • Epstein-Barr virus contributes to the malignant phenotype and to apoptosis resistance in Burkitt's lymphoma cell line Akata
    • Komano, J., M. Sugiura, and K. Takada. 1998. Epstein-Barr virus contributes to the malignant phenotype and to apoptosis resistance in Burkitt's lymphoma cell line Akata. J. Virol. 72:9150-9156.
    • (1998) J. Virol. , vol.72 , pp. 9150-9156
    • Komano, J.1    Sugiura, M.2    Takada, K.3
  • 21
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene bcl-2 and its role in regulating apoptosis
    • Kroemer, G. 1997. The proto-oncogene bcl-2 and its role in regulating apoptosis. Nat. Med. 3:614-620.
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 22
    • 0026639932 scopus 로고
    • The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
    • Lakshmi, R., M. Debbas, Sabbatini, D. Hockenberry, S. Korsmeyer, and E. White. 1992. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proc. Natl. Acad. Sci. USA 89:7742-7746.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7742-7746
    • Lakshmi, R.1    Debbas, M.2    Sabbatini3    Hockenberry, D.4    Korsmeyer, S.5    White, E.6
  • 23
    • 0029038135 scopus 로고
    • Apoptosis, cancer, and the p53 tumor suppressor gene
    • Lee, J., and A. Berenstein. 1995. Apoptosis, cancer, and the p53 tumor suppressor gene. Cancer Metastasis Rev. 14:149-161.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 149-161
    • Lee, J.1    Berenstein, A.2
  • 24
    • 0026562711 scopus 로고
    • BHRF1 of Epstein-Barr virus, which is homologous to human proto-oncogenc bcl2, is not essential for transformation of B cells or for virus replication in vitro
    • Lee, M., and J. Yates. 1992. BHRF1 of Epstein-Barr virus, which is homologous to human proto-oncogenc bcl2, is not essential for transformation of B cells or for virus replication in vitro. J. Virol. 66:1899-1906.
    • (1992) J. Virol. , vol.66 , pp. 1899-1906
    • Lee, M.1    Yates, J.2
  • 25
    • 0029849215 scopus 로고    scopus 로고
    • Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly(ADP-ribose) polymerase and restores the NF-kappaB signaling pathway
    • Mandal, M., S. Maggirwar, N. Sharma, S. Kaufmann, S. Sun, and R. Kumar. 1996. Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly(ADP-ribose) polymerase and restores the NF-kappaB signaling pathway. J. Biol. Chem. 271:30354-30354.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30354-30354
    • Mandal, M.1    Maggirwar, S.2    Sharma, N.3    Kaufmann, S.4    Sun, S.5    Kumar, R.6
  • 26
    • 0025932085 scopus 로고
    • BHRF1, the Epstein-Barr virus gene with homology to bcl-2, is dispensable for B-lymphocyte transformation and virus replication
    • Marchini, A., B. Tomkinson, J. Cohen, and E. Kieff. 1991. BHRF1, the Epstein-Barr virus gene with homology to bcl-2, is dispensable for B-lymphocyte transformation and virus replication. J. Virol. 65:5991-6000.
    • (1991) J. Virol. , vol.65 , pp. 5991-6000
    • Marchini, A.1    Tomkinson, B.2    Cohen, J.3    Kieff, E.4
  • 27
    • 0030058818 scopus 로고    scopus 로고
    • Bcl-2 but not its EBV-encoded homologue, BHRF1, is commonly expressed in postransplantation lymphoproliferative disorders
    • Murray, P., L. Swinnen, C. Constandinou, J. Pyle, T. Carr, J. Hardwick, and R. Ambinder. 1996. Bcl-2 but not its EBV-encoded homologue, BHRF1, is commonly expressed in postransplantation lymphoproliferative disorders. Blood 87:706-711.
    • (1996) Blood , vol.87 , pp. 706-711
    • Murray, P.1    Swinnen, L.2    Constandinou, C.3    Pyle, J.4    Carr, T.5    Hardwick, J.6    Ambinder, R.7
  • 28
    • 0028175759 scopus 로고
    • Targeted disruption of Bcl-2 alpha beta in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • Nakayama, K., I. Negishi, K. Kuida, H. Sawa, and D. Loh. 1994. Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc. Natl. Acad. Sci. USA 91:3700-3704.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Negishi, I.2    Kuida, K.3    Sawa, H.4    Loh, D.5
  • 29
    • 0030893693 scopus 로고    scopus 로고
    • Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene
    • Nava, V., E. Cheng, M. Veliuona, S. Zou, R. Clem, M. Mayer, and J. Hardwick. 1997. Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene. J. Virol. 71:4118-4122.
    • (1997) J. Virol. , vol.71 , pp. 4118-4122
    • Nava, V.1    Cheng, E.2    Veliuona, M.3    Zou, S.4    Clem, R.5    Mayer, M.6    Hardwick, J.7
  • 30
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., G. Migliorati, M. C. Pagliacc, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139: 271-279.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacc, M.C.3    Grignani, F.4    Riccardi, C.5
  • 31
    • 0030665808 scopus 로고    scopus 로고
    • Green fluorescent protein as a signal for protein-protein interactions
    • Park, S.-Y., and R. Raines. 1997. Green fluorescent protein as a signal for protein-protein interactions. Protein Sci. 6:2344-2349.
    • (1997) Protein Sci. , vol.6 , pp. 2344-2349
    • Park, S.-Y.1    Raines, R.2
  • 32
    • 0023989064 scopus 로고
    • Improved tools for biological sequence comparison
    • Pearson, W., and D. Lipman. 1988. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85:2444-2448.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2444-2448
    • Pearson, W.1    Lipman, D.2
  • 33
    • 0031054439 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue
    • Sarid, R., T. Sato, R. Bohenzky, J. Russo, and V. Chang. 1997. Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue. Nat. Med. 3:293-298.
    • (1997) Nat. Med. , vol.3 , pp. 293-298
    • Sarid, R.1    Sato, T.2    Bohenzky, R.3    Russo, J.4    Chang, V.5
  • 34
    • 0030901628 scopus 로고    scopus 로고
    • Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2
    • Shibasaki, F., E. Kondo, T. Akagi, and F. McKeon. 1997. Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2. Nature 386:728-731.
    • (1997) Nature , vol.386 , pp. 728-731
    • Shibasaki, F.1    Kondo, E.2    Akagi, T.3    McKeon, F.4
  • 35
    • 0027479343 scopus 로고
    • Epstein-Barr virus-associated non-Hodgkin's lymphoma in patients with the human immunodeficiency virus
    • Shibata, M., L. Wiess, A. Hernandez, B. Nathwani, L. Bernstein, and A. Levine. 1993. Epstein-Barr virus-associated non-Hodgkin's lymphoma in patients with the human immunodeficiency virus. Blood 81:2102-2109.
    • (1993) Blood , vol.81 , pp. 2102-2109
    • Shibata, M.1    Wiess, L.2    Hernandez, A.3    Nathwani, B.4    Bernstein, L.5    Levine, A.6
  • 36
    • 0026527758 scopus 로고
    • Pattern-induced multi-sequence alignment algorithm employing secondary structure-dependent gap penalties for use in comparative protein modeling
    • Smith, R., and T. F. Smith. 1992. Pattern-induced multi-sequence alignment algorithm employing secondary structure-dependent gap penalties for use in comparative protein modeling. Protein Eng. 5:35-41.
    • (1992) Protein Eng. , vol.5 , pp. 35-41
    • Smith, R.1    Smith, T.F.2
  • 37
    • 0031019739 scopus 로고
    • Interaction between the C. elegans cell-death regulators CED-9 and CED-4
    • Spector, M., S. Desnoyers, D. Hoeppner, and M. Hengartner. 1994. Interaction between the C. elegans cell-death regulators CED-9 and CED-4. Nature 385:653-656.
    • (1994) Nature , vol.385 , pp. 653-656
    • Spector, M.1    Desnoyers, S.2    Hoeppner, D.3    Hengartner, M.4
  • 40
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.1
  • 41
    • 0021679848 scopus 로고
    • Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
    • Tsujimoto, Y., L. Finger, J. Yunis, P. Nowell, and C. Croce. 1984. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 266:1097-1099.
    • (1984) Science , vol.266 , pp. 1097-1099
    • Tsujimoto, Y.1    Finger, L.2    Yunis, J.3    Nowell, P.4    Croce, C.5
  • 42
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis, D., C. Sorenson, J. Shutter, and S. Korsmeyer. 1993. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75:229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.1    Sorenson, C.2    Shutter, J.3    Korsmeyer, S.4
  • 43
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin, X.-M., Z. Oltvai, and S. Korsmeyer. 1994. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369:321-323.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.-M.1    Oltvai, Z.2    Korsmeyer, S.3
  • 44
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou, H., W. Henzel, X. Liu, A. Lutschg, and X. Wang. 1997. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.2    Liu, X.3    Lutschg, A.4    Wang, X.5


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