Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution

Oncotarget

Volumn 6, Issue 30, 2015, Pages 30017-30034

  Xu, Wenjuan ^a   Jing, Linlin ^a   Wang, Quanshi ^a   Lin, Chung Chih ^b   Chen, Xiaoting ^c   Diao, Jianxin ^a   Liu, Yuanliang ^a   Sun, Xuegang ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Bax; Cancer; DRP1; Intrinsic apoptosis; PGAM5L

Indexed keywords

ARENOBUFAGIN; BUFADIENOLIDE; CISPLATIN; DYNAMIN; DYNAMIN RELATED PROTEIN 1; PHOSPHOGLYCERATE MUTASE; PHOSPHOGLYCERATE MUTASE 5; PROTEIN BAX; STAUROSPORINE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BUFADIENOLIDE DERIVATIVE; CARRIER PROTEIN; DNM1L PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN; MULTIPROTEIN COMPLEX; PGAM5 PROTEIN, HUMAN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MOUSE; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; ANIMAL; BAGG ALBINO MOUSE; COLORECTAL NEOPLASMS; CONFOCAL MICROSCOPY; DRUG EFFECTS; DRUG SCREENING; GENETICS; HCT 116 CELL LINE; HELA CELL LINE; MCF-7 CELL LINE; METABOLISM; NUDE MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; BUFANOLIDES; CARRIER PROTEINS; CELL LINE, TUMOR; CISPLATIN; COLORECTAL NEOPLASMS; GTP PHOSPHOHYDROLASES; HCT116 CELLS; HELA CELLS; HUMANS; MCF-7 CELLS; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, CONFOCAL; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIAL PROTEINS; MULTIPROTEIN COMPLEXES; PHOSPHOPROTEIN PHOSPHATASES; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; STAUROSPORINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84945152455     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5013     Document Type: Article

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