Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice

Virology

Volumn 349, Issue 2, 2006, Pages 335-346

  Jacomy, Hélène ^a   Fragoso, Gabriela ^b   Almazan, Guillermina ^b   Mushynski, Walter E ^c   Talbot, Pierre J ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

^b Department of Pharmacology and Therapeutics ^*  (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Chronic encephalitis; Coronavirus; HCoV OC43; Human coronavirus; Motor disabilities; Neurodegeneration; OC43; Persistence

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORONAVIRUS; DISABILITY; EMBRYO; ENCEPHALITIS; INFECTION SENSITIVITY; MOTOR ACTIVITY; MOUSE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; REFLEX; SURVIVAL; VIRUS INFECTION; VIRUS STRAIN;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CORONAVIRUS INFECTIONS; CORONAVIRUS OC43, HUMAN; DISEASE MODELS, ANIMAL; ENCEPHALITIS, VIRAL; FEMALE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOTOR ACTIVITY; NECROSIS; NEUROGLIA; NEURONS; RNA, VIRAL; TELENCEPHALON;

ANIMALIA; CORONAVIRUS;

EID: 33646856866     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.01.049     Document Type: Article

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