-
1
-
-
0037831023
-
The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R)
-
National Comorbidity Survey Replication
-
Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS, National Comorbidity Survey Replication (2003) The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 289:3095–3105
-
(2003)
JAMA
, vol.289
, pp. 3095-3105
-
-
Kessler, R.C.1
Berglund, P.2
Demler, O.3
Jin, R.4
Koretz, D.5
Merikangas, K.R.6
Rush, A.J.7
Walters, E.E.8
Wang, P.S.9
-
2
-
-
84922075404
-
Faster, better, stronger: Towards new antidepressant therapeutic strategies
-
O’Leary OF, Dinan TG, Cryan JF (2015) Faster, better, stronger: towards new antidepressant therapeutic strategies. Eur J Pharmacol 753:32–50
-
(2015)
Eur J Pharmacol
, vol.753
, pp. 32-50
-
-
O’Leary, O.F.1
Dinan, T.G.2
Cryan, J.F.3
-
3
-
-
84942552433
-
Towards new mechanisms: An update on therapeutics for treatment-resistant major depressive disorder
-
Papakostas GI, Ionescu DF (2015) Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder. Mol Psychiatry 20:1142–1150
-
(2015)
Mol Psychiatry
, vol.20
, pp. 1142-1150
-
-
Papakostas, G.I.1
Ionescu, D.F.2
-
4
-
-
33751338530
-
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report
-
Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Niederehe G, Thase ME, Lavori PW, Lebowitz BD, McGrath PJ, Rosenbaum JF, Sackeim HA, Kupfer DJ, Luther J, Fava M (2006) Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry 163:1905–1917
-
(2006)
Am J Psychiatry
, vol.163
, pp. 1905-1917
-
-
Rush, A.J.1
Trivedi, M.H.2
Wisniewski, S.R.3
Nierenberg, A.A.4
Stewart, J.W.5
Warden, D.6
Niederehe, G.7
Thase, M.E.8
Lavori, P.W.9
Lebowitz, B.D.10
McGrath, P.J.11
Rosenbaum, J.F.12
Sackeim, H.A.13
Kupfer, D.J.14
Luther, J.15
Fava, M.16
-
5
-
-
84876988698
-
Lack of clinical therapeutic benefit of antidepressants is associated overall activation of the inflammatory system
-
Carvalho LA, Torre JP, Papadopoulos AS, Poon L, Juruena MF, Markopoulou K, Cleare AJ, Pariante CM (2013) Lack of clinical therapeutic benefit of antidepressants is associated overall activation of the inflammatory system. J Affect Disord 148:136–140
-
(2013)
J Affect Disord
, vol.148
, pp. 136-140
-
-
Carvalho, L.A.1
Torre, J.P.2
Papadopoulos, A.S.3
Poon, L.4
Juruena, M.F.5
Markopoulou, K.6
Cleare, A.J.7
Pariante, C.M.8
-
6
-
-
84872500205
-
Candidate genes expression profile associated with antidepressants response in the GENDEP study: Differentiating between baseline ‘predictors’ and longitudinal ‘targets’
-
Cattaneo A, Gennarelli M, Uher R, Breen G, Farmer A, Aitchison KJ, Craig IW, Anacker C, Zunsztain PA, McGuffin P, Pariante CM (2013) Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline ‘predictors’ and longitudinal ‘targets’. Neuropsychopharmacology 38:377–385
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 377-385
-
-
Cattaneo, A.1
Gennarelli, M.2
Uher, R.3
Breen, G.4
Farmer, A.5
Aitchison, K.J.6
Craig, I.W.7
Anacker, C.8
Zunsztain, P.A.9
McGuffin, P.10
Pariante, C.M.11
-
7
-
-
33845213789
-
Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy
-
O’Brien SM, Scully P, Fitzgerald P, Scott LV, Dinan TG (2007) Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy. J Psychiatric Res 41:326–331
-
(2007)
J Psychiatric Res
, vol.41
, pp. 326-331
-
-
O’Brien, S.M.1
Scully, P.2
Fitzgerald, P.3
Scott, L.V.4
Dinan, T.G.5
-
8
-
-
84914132272
-
An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline
-
Uher R, Tansey KE, Dew T, Maier W, Mors O, Hauser J, Dernovsek MZ, Henigsberg N, Souery D, Farmer A, McGuffin P (2014) An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline. Am J Psychiatry 171:1278–1286
-
(2014)
Am J Psychiatry
, vol.171
, pp. 1278-1286
-
-
Uher, R.1
Tansey, K.E.2
Dew, T.3
Maier, W.4
Mors, O.5
Hauser, J.6
Dernovsek, M.Z.7
Henigsberg, N.8
Souery, D.9
Farmer, A.10
McGuffin, P.11
-
9
-
-
67349120985
-
Higher plasma interleukin-6 (IL-6) level is associated with SSRI-or SNRI-refractory depression
-
Yoshimura R, Hori H, Ikenouchi-Sugita A, Umene-Nakano W, Ueda N, Nakamura J (2009) Higher plasma interleukin-6 (IL-6) level is associated with SSRI-or SNRI-refractory depression. Prog Neuropsychopharmacol Biol Psychiatry 33:722–726
-
(2009)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.33
, pp. 722-726
-
-
Yoshimura, R.1
Hori, H.2
Ikenouchi-Sugita, A.3
Umene-Nakano, W.4
Ueda, N.5
Nakamura, J.6
-
10
-
-
84945254083
-
Neuroscience, mental health and the immune system: Overcoming the brain-mind-body trichotomy
-
Pariante CM (2016) Neuroscience, mental health and the immune system: overcoming the brain-mind-body trichotomy. Epidemiol Psychiatr Sci 25(2):101–105
-
(2016)
Epidemiol Psychiatr Sci
, vol.25
, Issue.2
, pp. 101-105
-
-
Pariante, C.M.1
-
12
-
-
84943405909
-
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET
-
Sandiego CM, Gallezot JD, Pittman B, Nabulsi N, Lim K, Lin SF, Matuskey D, Lee JY, O’Connor KC, Huang Y, Carson RE, Hannestad J, Cosgrove KP (2015) Imaging robust microglial activation after lipopolysaccharide administration in humans with PET. Proc Natl Acad Sci U S A 112:12468–12473
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 12468-12473
-
-
Sandiego, C.M.1
Gallezot, J.D.2
Pittman, B.3
Nabulsi, N.4
Lim, K.5
Lin, S.F.6
Matuskey, D.7
Lee, J.Y.8
O’Connor, K.C.9
Huang, Y.10
Carson, R.E.11
Hannestad, J.12
Cosgrove, K.P.13
-
13
-
-
84949292691
-
Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances
-
Haapakoski R, Ebmeier KP, Alenius H, Kivimaki M (2016) Innate and adaptive immunity in the development of depression: an update on current knowledge and technological advances. Prog Neuropsychopharmacol Biol Psychiatry 66:63–72
-
(2016)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.66
, pp. 63-72
-
-
Haapakoski, R.1
Ebmeier, K.P.2
Alenius, H.3
Kivimaki, M.4
-
14
-
-
84925945862
-
The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders
-
Morris G, Berk M (2015) The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders. BMC Med 13:68
-
(2015)
BMC Med
, vol.13
, pp. 68
-
-
Morris, G.1
Berk, M.2
-
15
-
-
84909595107
-
Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress
-
Hodes GE, Pfau ML, Leboeuf M, Golden SA, Christoffel DJ, Bregman D, Rebusi N, Heshmati M, Aleyasin H, Warren BL, Lebonte B, Horn S, Lapidus KA, Stelzhammer V, Wong EH, Bahn S, Krishnan V, Bolanos-Guzman CA, Murrough JW, Merad M, Russo SJ (2014) Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress. Proc Natl Acad Sci U S A 111:16136–16141
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 16136-16141
-
-
Hodes, G.E.1
Pfau, M.L.2
Leboeuf, M.3
Golden, S.A.4
Christoffel, D.J.5
Bregman, D.6
Rebusi, N.7
Heshmati, M.8
Aleyasin, H.9
Warren, B.L.10
Lebonte, B.11
Horn, S.12
Lapidus, K.A.13
Stelzhammer, V.14
Wong, E.H.15
Bahn, S.16
Krishnan, V.17
Bolanos-Guzman, C.A.18
Murrough, J.W.19
Merad, M.20
Russo, S.J.21
more..
-
16
-
-
84929379817
-
Anti-inflammatory intervention in depression--reply
-
Kohler O, Benros ME, Krogh J (2015) Anti-inflammatory intervention in depression--reply. JAMA Psychiatry 72:512–513
-
(2015)
JAMA Psychiatry
, vol.72
, pp. 512-513
-
-
Kohler, O.1
Benros, M.E.2
Krogh, J.3
-
17
-
-
84875544837
-
Neuroinflammation and psychiatric illness
-
Najjar S, Pearlman DM, Alper K, Najjar A, Devinsky O (2013) Neuroinflammation and psychiatric illness. J Neuroinflammation 10:43
-
(2013)
J Neuroinflammation
, vol.10
, pp. 43
-
-
Najjar, S.1
Pearlman, D.M.2
Alper, K.3
Najjar, A.4
Devinsky, O.5
-
18
-
-
84976872227
-
Activation of the reward system boosts innate and adaptive immunity
-
Ben-Shaanan TL, Azulay-Debby H, Dubovik T, Starosvetsky E, Korin B, Schiller M, Green NL, Admon Y, Hakim F, Shen-Orr SS, Rolls A (2016) Activation of the reward system boosts innate and adaptive immunity. Nat Med 22:940–944
-
(2016)
Nat Med
, vol.22
, pp. 940-944
-
-
Ben-Shaanan, T.L.1
Azulay-Debby, H.2
Dubovik, T.3
Starosvetsky, E.4
Korin, B.5
Schiller, M.6
Green, N.L.7
Admon, Y.8
Hakim, F.9
Shen-Orr, S.S.10
Rolls, A.11
-
19
-
-
84942518278
-
Revisiting the mechanisms of CNS immune privilege
-
Louveau A, Harris TH, Kipnis J (2015) Revisiting the mechanisms of CNS immune privilege. Trends Immunol 36:569–577
-
(2015)
Trends Immunol
, vol.36
, pp. 569-577
-
-
Louveau, A.1
Harris, T.H.2
Kipnis, J.3
-
20
-
-
78651412528
-
Immune modulation of learning, memory, neural plasticity and neurogenesis
-
Yirmiya R, Goshen I (2011) Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behav Immun 25:181–213
-
(2011)
Brain Behav Immun
, vol.25
, pp. 181-213
-
-
Yirmiya, R.1
Goshen, I.2
-
22
-
-
84878138965
-
Inflammation and neurological diseaserelated genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities
-
Savitz J, Frank MB, Victor T, Bebak M, Marino JH, Bellgowan PS, McKinney BA, Bodurka J, Kent Teague T, Drevets WC (2013) Inflammation and neurological diseaserelated genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities. Brain Behav Immun 31:161–171
-
(2013)
Brain Behav Immun
, vol.31
, pp. 161-171
-
-
Savitz, J.1
Frank, M.B.2
Victor, T.3
Bebak, M.4
Marino, J.H.5
Bellgowan, P.S.6
McKinney, B.A.7
Bodurka, J.8
Kent Teague, T.9
Drevets, W.C.10
-
23
-
-
64549126898
-
Bipolar and major depressive disorder: Neuroimaging the developmental-degenerative divide
-
Savitz J, Drevets WC (2009) Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide. Neurosci Biobehav Rev 33:699–771
-
(2009)
Neurosci Biobehav Rev
, vol.33
, pp. 699-771
-
-
Savitz, J.1
Drevets, W.C.2
-
24
-
-
84877704720
-
Genetics of bipolar disorder
-
Craddock N, Sklar P (2013) Genetics of bipolar disorder. Lancet 381:1654–1662
-
(2013)
Lancet
, vol.381
, pp. 1654-1662
-
-
Craddock, N.1
Sklar, P.2
-
25
-
-
67650033123
-
Unipolar depressive disorders have a common genotype
-
Edvardsen J, Torgersen S, Roysamb E, Lygren S, Skre I, Onstad S, Oien PA (2009) Unipolar depressive disorders have a common genotype. J Affect Disord 117:30–41
-
(2009)
J Affect Disord
, vol.117
, pp. 30-41
-
-
Edvardsen, J.1
Torgersen, S.2
Roysamb, E.3
Lygren, S.4
Skre, I.5
Onstad, S.6
Oien, P.A.7
-
26
-
-
84961752062
-
Polygenic dissection of major depression clinical heterogeneity
-
Milaneschi Y, Lamers F, Peyrot WJ, Abdellaoui A, Willemsen G, Hottenga JJ, Jansen R, Mbarek H, Dehghan A, Lu C, Group Ciw, Boomsma DI, Penninx BW (2016) Polygenic dissection of major depression clinical heterogeneity. Mol Psychiatry 21:516–522
-
(2016)
Mol Psychiatry
, vol.21
, pp. 516-522
-
-
Milaneschi, Y.1
Lamers, F.2
Peyrot, W.J.3
Abdellaoui, A.4
Willemsen, G.5
Hottenga, J.J.6
Jansen, R.7
Mbarek, H.8
Dehghan, A.9
Lu, C.10
Group, C.11
Boomsma, D.I.12
Penninx, B.W.13
-
27
-
-
79953662385
-
Immune system to brain signaling: Neuropsychopharmacological implications
-
Capuron L, Miller AH (2011) Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol Ther 130:226–238
-
(2011)
Pharmacol Ther
, vol.130
, pp. 226-238
-
-
Capuron, L.1
Miller, A.H.2
-
28
-
-
85014119974
-
Monocyte trafficking to the brain with stress and inflammation: A novel axis of immune-to-brain communication that influences mood and behavior
-
Wohleb ES, McKim DB, Sheridan JF, Godbout JP (2014) Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior. Front Neurosci 8:447
-
(2014)
Front Neurosci
, vol.8
, pp. 447
-
-
Wohleb, E.S.1
McKim, D.B.2
Sheridan, J.F.3
Godbout, J.P.4
-
29
-
-
84936871460
-
Structural and functional features of central nervous system lymphatic vessels
-
Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, Derecki NC, Castle D, Mandell JW, Lee KS, Harris TH, Kipnis J (2015) Structural and functional features of central nervous system lymphatic vessels. Nature 523:337–341
-
(2015)
Nature
, vol.523
, pp. 337-341
-
-
Louveau, A.1
Smirnov, I.2
Keyes, T.J.3
Eccles, J.D.4
Rouhani, S.J.5
Peske, J.D.6
Derecki, N.C.7
Castle, D.8
Mandell, J.W.9
Lee, K.S.10
Harris, T.H.11
Kipnis, J.12
-
32
-
-
77956231165
-
Glia: The many ways to modulate synaptic plasticity
-
Ben Achour S, Pascual O (2010) Glia: the many ways to modulate synaptic plasticity. Neurochem Int 57:440–445
-
(2010)
Neurochem Int
, vol.57
, pp. 440-445
-
-
Ben Achour, S.1
Pascual, O.2
-
33
-
-
84957436714
-
Microglial M1/M2 polarization and metabolic states
-
Orihuela R, McPherson CA, Harry GJ (2016) Microglial M1/M2 polarization and metabolic states. Br J Pharmacol 173(4):649–665
-
(2016)
Br J Pharmacol
, vol.173
, Issue.4
, pp. 649-665
-
-
Orihuela, R.1
McPherson, C.A.2
Harry, G.J.3
-
34
-
-
84979730436
-
A polarizing question: Do M1 and M2 microglia exist?
-
Ransohoff RM (2016) A polarizing question: do M1 and M2 microglia exist? Nat Neurosci 19:987–991
-
(2016)
Nat Neurosci
, vol.19
, pp. 987-991
-
-
Ransohoff, R.M.1
-
35
-
-
84958106930
-
Differential roles of M1 and M2 microglia in neurodegenerative diseases
-
Tang Y, Le W (2015) Differential roles of M1 and M2 microglia in neurodegenerative diseases. Mol Neurobiol 53(2):1181–1194
-
(2015)
Mol Neurobiol
, vol.53
, Issue.2
, pp. 1181-1194
-
-
Tang, Y.1
Le, W.2
-
36
-
-
84902549638
-
Neuroinflammation and M2 microglia: The good, the bad, and the inflamed
-
Cherry JD, Olschowka JA, O’Banion MK (2014) Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. J Neuroinflammation 11:98
-
(2014)
J Neuroinflammation
, vol.11
, pp. 98
-
-
Cherry, J.D.1
Olschowka, J.A.2
O’Banion, M.K.3
-
37
-
-
84899418705
-
Microglia and brain macrophages in the molecular age: From origin to neuropsychiatric disease
-
Prinz M, Priller J (2014) Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat Rev Neurosci 15:300–312
-
(2014)
Nat Rev Neurosci
, vol.15
, pp. 300-312
-
-
Prinz, M.1
Priller, J.2
-
38
-
-
81155157520
-
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
-
Steiner J, Walter M, Gos T, Guillemin GJ, Bernstein HG, Sarnyai Z, Mawrin C, Brisch R, Bielau H, Meyer zu Schwabedissen L, Bogerts B, Myint AM (2011) Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission? J Neuroinflammation 8:94
-
(2011)
J Neuroinflammation
, vol.8
, pp. 94
-
-
Steiner, J.1
Walter, M.2
Gos, T.3
Guillemin, G.J.4
Bernstein, H.G.5
Sarnyai, Z.6
Mawrin, C.7
Brisch, R.8
Bielau, H.9
Meyer Zu Schwabedissen, L.10
Bogerts, B.11
Myint, A.M.12
-
39
-
-
84872168596
-
Microglia: Scapegoat, saboteur, or something else?
-
Aguzzi A, Barres BA, Bennett ML (2013) Microglia: scapegoat, saboteur, or something else? Science 339:156–161
-
(2013)
Science
, vol.339
, pp. 156-161
-
-
Aguzzi, A.1
Barres, B.A.2
Bennett, M.L.3
-
40
-
-
84858025498
-
The role of glial cells in synapse elimination
-
Chung WS, Barres BA (2012) The role of glial cells in synapse elimination. Curr Opin Neurobiol 22:438–445
-
(2012)
Curr Opin Neurobiol
, vol.22
, pp. 438-445
-
-
Chung, W.S.1
Barres, B.A.2
-
41
-
-
84896692474
-
Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
-
Zhan Y, Paolicelli RC, Sforazzini F, Weinhard L, Bolasco G, Pagani F, Vyssotski AL, Bifone A, Gozzi A, Ragozzino D, Gross CT (2014) Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior. Nat Neurosci 17:400–406
-
(2014)
Nat Neurosci
, vol.17
, pp. 400-406
-
-
Zhan, Y.1
Paolicelli, R.C.2
Sforazzini, F.3
Weinhard, L.4
Bolasco, G.5
Pagani, F.6
Vyssotski, A.L.7
Bifone, A.8
Gozzi, A.9
Ragozzino, D.10
Gross, C.T.11
-
44
-
-
77952311924
-
Regulation of learning and memory by meningeal immunity: A key role for IL-4
-
Derecki NC, Cardani AN, Yang CH, Quinnies KM, Crihfield A, Lynch KR, Kipnis J (2010) Regulation of learning and memory by meningeal immunity: a key role for IL-4. J Exp Med 207:1067–1080
-
(2010)
J Exp Med
, vol.207
, pp. 1067-1080
-
-
Derecki, N.C.1
Cardani, A.N.2
Yang, C.H.3
Quinnies, K.M.4
Crihfield, A.5
Lynch, K.R.6
Kipnis, J.7
-
45
-
-
84894597873
-
Febrile illness and pro-inflammatory cytokines are associated with lower neurodevelopmental scores in Bangladeshi infants living in poverty
-
Jiang NM, Tofail F, Moonah SN, Scharf RJ, Taniuchi M, Ma JZ, Hamadani JD, Gurley ES, Houpt ER, Azziz-Baumgartner E, Haque R, Petri WA Jr. (2014) Febrile illness and pro-inflammatory cytokines are associated with lower neurodevelopmental scores in Bangladeshi infants living in poverty. BMC Pediatr 14:50
-
(2014)
BMC Pediatr
, vol.14
, pp. 50
-
-
Jiang, N.M.1
Tofail, F.2
Moonah, S.N.3
Scharf, R.J.4
Taniuchi, M.5
Ma, J.Z.6
Hamadani, J.D.7
Gurley, E.S.8
Houpt, E.R.9
Azziz-Baumgartner, E.10
Haque, R.11
Petri, W.A.12
-
46
-
-
2542596271
-
T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions
-
Kipnis J, Cohen H, Cardon M, Ziv Y, Schwartz M (2004) T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions. Proc Natl Acad Sci U S A 101:8180–8185
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8180-8185
-
-
Kipnis, J.1
Cohen, H.2
Cardon, M.3
Ziv, Y.4
Schwartz, M.5
-
47
-
-
64249134817
-
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis
-
Wolf SA, Steiner B, Akpinarli A, Kammertoens T, Nassenstein C, Braun A, Blankenstein T, Kempermann G (2009) CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis. J Immunol 182:3979–3984
-
(2009)
J Immunol
, vol.182
, pp. 3979-3984
-
-
Wolf, S.A.1
Steiner, B.2
Akpinarli, A.3
Kammertoens, T.4
Nassenstein, C.5
Braun, A.6
Blankenstein, T.7
Kempermann, G.8
-
48
-
-
31544460682
-
Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood
-
Ziv Y, Ron N, Butovsky O, Landa G, Sudai E, Greenberg N, Cohen H, Kipnis J, Schwartz M (2006) Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nat Neurosci 9:268–275
-
(2006)
Nat Neurosci
, vol.9
, pp. 268-275
-
-
Ziv, Y.1
Ron, N.2
Butovsky, O.3
Landa, G.4
Sudai, E.5
Greenberg, N.6
Cohen, H.7
Kipnis, J.8
Schwartz, M.9
-
49
-
-
84893115383
-
Innate immunity to Toxoplasma gondii infection
-
Yarovinsky F (2014) Innate immunity to Toxoplasma gondii infection. Nat Rev Immunol 14:109–121
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 109-121
-
-
Yarovinsky, F.1
-
50
-
-
0033049143
-
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
-
Moalem G, Leibowitz-Amit R, Yoles E, Mor F, Cohen IR, Schwartz M (1999) Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat Med 5:49–55
-
(1999)
Nat Med
, vol.5
, pp. 49-55
-
-
Moalem, G.1
Leibowitz-Amit, R.2
Yoles, E.3
Mor, F.4
Cohen, I.R.5
Schwartz, M.6
-
51
-
-
0037223515
-
Autoreactive T cells promote post-traumatic healing in the central nervous system
-
Hofstetter HH, Sewell DL, Liu F, Sandor M, Forsthuber T, Lehmann PV, Fabry Z (2003) Autoreactive T cells promote post-traumatic healing in the central nervous system. J Neuroimmunol 134:25–34
-
(2003)
J Neuroimmunol
, vol.134
, pp. 25-34
-
-
Hofstetter, H.H.1
Sewell, D.L.2
Liu, F.3
Sandor, M.4
Forsthuber, T.5
Lehmann, P.V.6
Fabry, Z.7
-
52
-
-
0036708987
-
Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity
-
Kipnis J, Mizrahi T, Yoles E, Ben-Nun A, Schwartz M (2002) Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity. J Neuroimmunol 130:78–85
-
(2002)
J Neuroimmunol
, vol.130
, pp. 78-85
-
-
Kipnis, J.1
Mizrahi, T.2
Yoles, E.3
Ben-Nun, A.4
Schwartz, M.5
-
53
-
-
0037293972
-
Cytokine-induced sickness behavior
-
Kelley KW, Bluthe RM, Dantzer R, Zhou JH, Shen WH, Johnson RW, Broussard SR (2003) Cytokine-induced sickness behavior. Brain Behav Immun 17(Suppl 1):S112–S118
-
(2003)
Brain Behav Immun
, vol.17
, pp. S112-S118
-
-
Kelley, K.W.1
Bluthe, R.M.2
Dantzer, R.3
Zhou, J.H.4
Shen, W.H.5
Johnson, R.W.6
Broussard, S.R.7
-
54
-
-
85007557181
-
Role of the Kynurenine metabolism pathway in inflammation-induced depression: Preclinical approaches
-
Dantzer R (2016) Role of the Kynurenine metabolism pathway in inflammation-induced depression: preclinical approaches. Curr Top Behav Neurosci. doi:10.1007/7854_2016_6
-
(2016)
Curr Top Behav Neurosci
-
-
Dantzer, R.1
-
55
-
-
84947617144
-
Gene networks specific for innate immunity define post-traumatic stress disorder
-
Breen MS, Maihofer AX, Glatt SJ, Tylee DS, Chandler SD, Tsuang MT, Risbrough VB, Baker DG, O’Connor DT, Nievergelt CM, Woelk CH (2015) Gene networks specific for innate immunity define post-traumatic stress disorder. Mol Psychiatry 20(12):1538–1545
-
(2015)
Mol Psychiatry
, vol.20
, Issue.12
, pp. 1538-1545
-
-
Breen, M.S.1
Maihofer, A.X.2
Glatt, S.J.3
Tylee, D.S.4
Chandler, S.D.5
Tsuang, M.T.6
Risbrough, V.B.7
Baker, D.G.8
O’Connor, D.T.9
Nievergelt, C.M.10
Woelk, C.H.11
-
56
-
-
0029931236
-
Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain
-
Glabinski AR, Balasingam V, Tani M, Kunkel SL, Strieter RM, Yong VW, Ransohoff RM (1996) Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol 156:4363–4368
-
(1996)
J Immunol
, vol.156
, pp. 4363-4368
-
-
Glabinski, A.R.1
Balasingam, V.2
Tani, M.3
Kunkel, S.L.4
Strieter, R.M.5
Yong, V.W.6
Ransohoff, R.M.7
-
57
-
-
0033794577
-
Characterization of binding sites for chemokines MCP-1 and MIP-1alpha on human brain microvessels
-
Andjelkovic AV, Pachter JS (2000) Characterization of binding sites for chemokines MCP-1 and MIP-1alpha on human brain microvessels. J Neurochem 75:1898–1906
-
(2000)
J Neurochem
, vol.75
, pp. 1898-1906
-
-
Andjelkovic, A.V.1
Pachter, J.S.2
-
58
-
-
85011914521
-
Serum proteomic profiles of depressive subtypes
-
Lamers F, Bot M, Jansen R, Chan MK, Cooper JD, Bahn S, Penninx BW (2016) Serum proteomic profiles of depressive subtypes. Transl Psychiatry 6:e851
-
(2016)
Transl Psychiatry
, vol.6
-
-
Lamers, F.1
Bot, M.2
Jansen, R.3
Chan, M.K.4
Cooper, J.D.5
Bahn, S.6
Penninx, B.W.7
-
59
-
-
84907876423
-
Targeting the inflammatory pathway as a therapeutic tool for major depression
-
Noto C, Rizzo LB, Mansur RB, McIntyre RS, Maes M, Brietzke E (2014) Targeting the inflammatory pathway as a therapeutic tool for major depression. Neuroimmunomodulation 21:131–139
-
(2014)
Neuroimmunomodulation
, vol.21
, pp. 131-139
-
-
Noto, C.1
Rizzo, L.B.2
Mansur, R.B.3
McIntyre, R.S.4
Maes, M.5
Brietzke, E.6
-
62
-
-
75849155537
-
A meta-analysis of cytokines in major depression
-
Dowlati Y, Herrmann N, Swardfager W, Liu H, Sham L, Reim EK, Lanctot KL (2010) A meta-analysis of cytokines in major depression. Biol Psychiatry 67:446–457
-
(2010)
Biol Psychiatry
, vol.67
, pp. 446-457
-
-
Dowlati, Y.1
Herrmann, N.2
Swardfager, W.3
Liu, H.4
Sham, L.5
Reim, E.K.6
Lanctot, K.L.7
-
63
-
-
84873279865
-
The role of the innate immune system in psychiatric disorders
-
Jones KA, Thomsen C (2013) The role of the innate immune system in psychiatric disorders. Mol Cell Neurosci 53:52–62
-
(2013)
Mol Cell Neurosci
, vol.53
, pp. 52-62
-
-
Jones, K.A.1
Thomsen, C.2
-
64
-
-
70449376943
-
Cytokines and glucocorticoid receptor signaling. Relevance to major depression
-
Pace TW, Miller AH (2009) Cytokines and glucocorticoid receptor signaling. Relevance to major depression. Ann N Y Acad Sci 1179:86–105
-
(2009)
Ann N Y Acad Sci
, vol.1179
, pp. 86-105
-
-
Pace, T.W.1
Miller, A.H.2
-
65
-
-
79953100305
-
Elevation of cerebrospinal fluid interleukin-1ss in bipolar disorder
-
Soderlund J, Olsson SK, Samuelsson M, Walther-Jallow L, Johansson C, Erhardt S, Landen M, Engberg G (2011) Elevation of cerebrospinal fluid interleukin-1ss in bipolar disorder. J Psychiatry Neurosci 36:114–118
-
(2011)
J Psychiatry Neurosci
, vol.36
, pp. 114-118
-
-
Soderlund, J.1
Olsson, S.K.2
Samuelsson, M.3
Walther-Jallow, L.4
Johansson, C.5
Erhardt, S.6
Landen, M.7
Engberg, G.8
-
66
-
-
84906331370
-
A review of the relationship between proinflammatory cytokines and major depressive disorder
-
Young JJ, Bruno D, Pomara N (2014) A review of the relationship between proinflammatory cytokines and major depressive disorder. J Affect Disord 169:15–20
-
(2014)
J Affect Disord
, vol.169
, pp. 15-20
-
-
Young, J.J.1
Bruno, D.2
Pomara, N.3
-
67
-
-
84893345725
-
Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder
-
Carvalho LA, Bergink V, Sumaski L, Wijkhuijs J, Hoogendijk WJ, Birkenhager TK, Drexhage HA (2014) Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder. Transl Psychiatry 4:e344
-
(2014)
Transl Psychiatry
, vol.4
-
-
Carvalho, L.A.1
Bergink, V.2
Sumaski, L.3
Wijkhuijs, J.4
Hoogendijk, W.J.5
Birkenhager, T.K.6
Drexhage, H.A.7
-
68
-
-
84958922228
-
Gene expression in major depressive disorder
-
Jansen R, Penninx BW, Madar V, Xia K, Milaneschi Y, Hottenga JJ, Hammerschlag AR, Beekman A, van der Wee N, Smit JH, Brooks AI, Tischfield J, Posthuma D, Schoevers R, van Grootheest G, Willemsen G, de Geus EJ, Boomsma DI, Wright FA, Zou F, Sun W, Sullivan PF (2016) Gene expression in major depressive disorder. Mol Psychiatry 21(3):339–347
-
(2016)
Mol Psychiatry
, vol.21
, Issue.3
, pp. 339-347
-
-
Jansen, R.1
Penninx, B.W.2
Madar, V.3
Xia, K.4
Milaneschi, Y.5
Hottenga, J.J.6
Hammerschlag, A.R.7
Beekman, A.8
Van Der Wee, N.9
Smit, J.H.10
Brooks, A.I.11
Tischfield, J.12
Posthuma, D.13
Schoevers, R.14
Van Grootheest, G.15
Willemsen, G.16
De Geus, E.J.17
Boomsma, D.I.18
Wright, F.A.19
Zou, F.20
Sun, W.21
Sullivan, P.F.22
more..
-
69
-
-
42049092538
-
A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes
-
Padmos RC, Hillegers MH, Knijff EM, Vonk R, Bouvy A, Staal FJ, de Ridder D, Kupka RW, Nolen WA, Drexhage HA (2008) A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry 65:395–407
-
(2008)
Arch Gen Psychiatry
, vol.65
, pp. 395-407
-
-
Padmos, R.C.1
Hillegers, M.H.2
Knijff, E.M.3
Vonk, R.4
Bouvy, A.5
Staal, F.J.6
De Ridder, D.7
Kupka, R.W.8
Nolen, W.A.9
Drexhage, H.A.10
-
70
-
-
84897514668
-
Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients
-
Powell TR, McGuffin P, D’Souza UM, Cohen-Woods S, Hosang GM, Martin C, Matthews K, Day RK, Farmer AE, Tansey KE, Schalkwyk LC (2014) Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients. PLoS One 9:e91076
-
(2014)
Plos One
, vol.9
-
-
Powell, T.R.1
McGuffin, P.2
D’Souza, U.M.3
Cohen-Woods, S.4
Hosang, G.M.5
Martin, C.6
Matthews, K.7
Day, R.K.8
Farmer, A.E.9
Tansey, K.E.10
Schalkwyk, L.C.11
-
71
-
-
80054745701
-
The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: A meta-analysis
-
Hannestad J, DellaGioia N, Bloch M (2011) The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis. Neuropsychopharmacology 36:2452–2459
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 2452-2459
-
-
Hannestad, J.1
Dellagioia, N.2
Bloch, M.3
-
72
-
-
84863718439
-
Symptomatic treatment of interferonalpha-induced depression in hepatitis C: A systematic review
-
Baraldi S, Hepgul N, Mondelli V, Pariante CM (2012) Symptomatic treatment of interferonalpha-induced depression in hepatitis C: a systematic review. J Clin Psychopharmacol 32:531–543
-
(2012)
J Clin Psychopharmacol
, vol.32
, pp. 531-543
-
-
Baraldi, S.1
Hepgul, N.2
Mondelli, V.3
Pariante, C.M.4
-
73
-
-
0032077571
-
Cytokines and sickness behavior
-
Dantzer R, Bluthe RM, Laye S, Bret-Dibat JL, Parnet P, Kelley KW (1998) Cytokines and sickness behavior. Ann N Y Acad Sci 840:586–590
-
(1998)
Ann N Y Acad Sci
, vol.840
, pp. 586-590
-
-
Dantzer, R.1
Bluthe, R.M.2
Laye, S.3
Bret-Dibat, J.L.4
Parnet, P.5
Kelley, K.W.6
-
74
-
-
63449122724
-
Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression
-
Miller AH, Maletic V, Raison CL (2009) Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry 65:732–741
-
(2009)
Biol Psychiatry
, vol.65
, pp. 732-741
-
-
Miller, A.H.1
Maletic, V.2
Raison, C.L.3
-
75
-
-
70349734652
-
Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals?
-
Capuron L, Fornwalt FB, Knight BT, Harvey PD, Ninan PT, Miller AH (2009) Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals? J Affect Disord 119:181–185
-
(2009)
J Affect Disord
, vol.119
, pp. 181-185
-
-
Capuron, L.1
Fornwalt, F.B.2
Knight, B.T.3
Harvey, P.D.4
Ninan, P.T.5
Miller, A.H.6
-
76
-
-
48949116081
-
Differences in depressive thoughts between major depressive disorder, IFN-alpha-induced depression, and depressive disorders among cancer patients
-
Pasquini M, Speca A, Mastroeni S, Delle Chiaie R, Sternberg CN, Biondi M (2008) Differences in depressive thoughts between major depressive disorder, IFN-alpha-induced depression, and depressive disorders among cancer patients. J Psychosom Res 65:153–156
-
(2008)
J Psychosom Res
, vol.65
, pp. 153-156
-
-
Pasquini, M.1
Speca, A.2
Mastroeni, S.3
Delle Chiaie, R.4
Sternberg, C.N.5
Biondi, M.6
-
77
-
-
70449769018
-
Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment
-
Bull SJ, Huezo-Diaz P, Binder EB, Cubells JF, Ranjith G, Maddock C, Miyazaki C, Alexander N, Hotopf M, Cleare AJ, Norris S, Cassidy E, Aitchison KJ, Miller AH, Pariante CM (2009) Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. Mol Psychiatry 14:1095–1104
-
(2009)
Mol Psychiatry
, vol.14
, pp. 1095-1104
-
-
Bull, S.J.1
Huezo-Diaz, P.2
Binder, E.B.3
Cubells, J.F.4
Ranjith, G.5
Maddock, C.6
Miyazaki, C.7
Alexander, N.8
Hotopf, M.9
Cleare, A.J.10
Norris, S.11
Cassidy, E.12
Aitchison, K.J.13
Miller, A.H.14
Pariante, C.M.15
-
78
-
-
84920365937
-
Prophylactic antidepressant treatment of interferon-induced depression in chronic hepatitis C: A systematic review and meta-analysis
-
Udina M, Hidalgo D, Navines R, Forns X, Sola R, Farre M, Capuron L, Vieta E, Martin-Santos R (2014) Prophylactic antidepressant treatment of interferon-induced depression in chronic hepatitis C: a systematic review and meta-analysis. J Clin Psychiatry 75:e1113–e1121
-
(2014)
J Clin Psychiatry
, vol.75
, pp. e1113-e1121
-
-
Udina, M.1
Hidalgo, D.2
Navines, R.3
Forns, X.4
Sola, R.5
Farre, M.6
Capuron, L.7
Vieta, E.8
Martin-Santos, R.9
-
79
-
-
84862779106
-
Neurobehavioral effects of interferon-alpha in patients with hepatitis-C: Symptom dimensions and responsiveness to paroxetine
-
McNutt MD, Liu S, Manatunga A, Royster EB, Raison CL, Woolwine BJ, Demetrashvili MF, Miller AH, Musselman DL (2012) Neurobehavioral effects of interferon-alpha in patients with hepatitis-C: symptom dimensions and responsiveness to paroxetine. Neuropsychopharmacology 37:1444–1454
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1444-1454
-
-
McNutt, M.D.1
Liu, S.2
Manatunga, A.3
Royster, E.B.4
Raison, C.L.5
Woolwine, B.J.6
Demetrashvili, M.F.7
Miller, A.H.8
Musselman, D.L.9
-
80
-
-
29844440963
-
Etanercept and clinical outcomes, fatigue, and depression in psoriasis: Double-blind placebo-controlled randomised phase III trial
-
Tyring S, Gottlieb A, Papp K, Gordon K, Leonardi C, Wang A, Lalla D, Woolley M, Jahreis A, Zitnik R, Cella D, Krishnan R (2006) Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. Lancet 367:29–35
-
(2006)
Lancet
, vol.367
, pp. 29-35
-
-
Tyring, S.1
Gottlieb, A.2
Papp, K.3
Gordon, K.4
Leonardi, C.5
Wang, A.6
Lalla, D.7
Woolley, M.8
Jahreis, A.9
Zitnik, R.10
Cella, D.11
Krishnan, R.12
-
81
-
-
84868323431
-
Stability and transitions of depressive subtypes over a 2-year follow-up
-
Lamers F, Rhebergen D, Merikangas KR, de Jonge P, Beekman AT, Penninx BW (2012) Stability and transitions of depressive subtypes over a 2-year follow-up. Psychol Med 42:2083–2093
-
(2012)
Psychol Med
, vol.42
, pp. 2083-2093
-
-
Lamers, F.1
Rhebergen, D.2
Merikangas, K.R.3
De Jonge, P.4
Beekman, A.T.5
Penninx, B.W.6
-
82
-
-
84918512616
-
Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder
-
Grosse L, Carvalho LA, Wijkhuijs AJ, Bellingrath S, Ruland T, Ambree O, Alferink J, Ehring T, Drexhage HA, Arolt V (2015) Clinical characteristics of inflammation-associated depression: monocyte gene expression is age-related in major depressive disorder. Brain Behav Immun 44:48–56
-
(2015)
Brain Behav Immun
, vol.44
, pp. 48-56
-
-
Grosse, L.1
Carvalho, L.A.2
Wijkhuijs, A.J.3
Bellingrath, S.4
Ruland, T.5
Ambree, O.6
Alferink, J.7
Ehring, T.8
Drexhage, H.A.9
Arolt, V.10
-
83
-
-
74949090006
-
The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder
-
Drexhage RC, Knijff EM, Padmos RC, Heul-Nieuwenhuijzen L, Beumer W, Versnel MA, Drexhage HA (2010) The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder. Expert Rev Neurother 10:59–76
-
(2010)
Expert Rev Neurother
, vol.10
, pp. 59-76
-
-
Drexhage, R.C.1
Knijff, E.M.2
Padmos, R.C.3
Heul-Nieuwenhuijzen, L.4
Beumer, W.5
Versnel, M.A.6
Drexhage, H.A.7
-
84
-
-
84942427794
-
Neuroimmune mechanisms of depression
-
Hodes GE, Kana V, Menard C, Merad M, Russo SJ (2015) Neuroimmune mechanisms of depression. Nat Neurosci 18:1386–1393
-
(2015)
Nat Neurosci
, vol.18
, pp. 1386-1393
-
-
Hodes, G.E.1
Kana, V.2
Menard, C.3
Merad, M.4
Russo, S.J.5
-
85
-
-
37249094173
-
From inflammation to sickness and depression: When the immune system subjugates the brain
-
Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9:46–56
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 46-56
-
-
Dantzer, R.1
O’Connor, J.C.2
Freund, G.G.3
Johnson, R.W.4
Kelley, K.W.5
-
86
-
-
36148988466
-
Effects of etanercept therapy on fatigue and symptoms of depression in subjects treated for moderate to severe plaque psoriasis for up to 96 weeks
-
Krishnan R, Cella D, Leonardi C, Papp K, Gottlieb AB, Dunn M, Chiou CF, Patel V, Jahreis A (2007) Effects of etanercept therapy on fatigue and symptoms of depression in subjects treated for moderate to severe plaque psoriasis for up to 96 weeks. Br J Dermatol 157:1275–1277
-
(2007)
Br J Dermatol
, vol.157
, pp. 1275-1277
-
-
Krishnan, R.1
Cella, D.2
Leonardi, C.3
Papp, K.4
Gottlieb, A.B.5
Dunn, M.6
Chiou, C.F.7
Patel, V.8
Jahreis, A.9
-
87
-
-
33646101010
-
TNFalpha signaling in depression and anxiety: Behavioral consequences of individual receptor targeting
-
Simen BB, Duman CH, Simen AA, Duman RS (2006) TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting. Biol Psychiatry 59:775–785
-
(2006)
Biol Psychiatry
, vol.59
, pp. 775-785
-
-
Simen, B.B.1
Duman, C.H.2
Simen, A.A.3
Duman, R.S.4
-
88
-
-
0034333060
-
Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factoralpha gene: Implications for emotional behavior
-
Yamada K, Iida R, Miyamoto Y, Saito K, Sekikawa K, Seishima M, Nabeshima T (2000) Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factoralpha gene: implications for emotional behavior. J Neuroimmunol 111:131–138
-
(2000)
J Neuroimmunol
, vol.111
, pp. 131-138
-
-
Yamada, K.1
Iida, R.2
Miyamoto, Y.3
Saito, K.4
Sekikawa, K.5
Seishima, M.6
Nabeshima, T.7
-
89
-
-
84876443867
-
Chronic administration of infliximab (TNF-alpha inhibitor) decreases depression and anxiety-like behaviour in rat model of chronic mild stress
-
Karson A, Demirtas T, Bayramgurler D, Balci F, Utkan T (2013) Chronic administration of infliximab (TNF-alpha inhibitor) decreases depression and anxiety-like behaviour in rat model of chronic mild stress. Basic Clin Pharmacol Toxicol 112:335–340
-
(2013)
Basic Clin Pharmacol Toxicol
, vol.112
, pp. 335-340
-
-
Karson, A.1
Demirtas, T.2
Bayramgurler, D.3
Balci, F.4
Utkan, T.5
-
90
-
-
84875277496
-
Antidepressant effects of TNF-alpha blockade in an animal model of depression
-
Krugel U, Fischer J, Radicke S, Sack U, Himmerich H (2013) Antidepressant effects of TNF-alpha blockade in an animal model of depression. J Psychiatric Res 47:611–616
-
(2013)
J Psychiatric Res
, vol.47
, pp. 611-616
-
-
Krugel, U.1
Fischer, J.2
Radicke, S.3
Sack, U.4
Himmerich, H.5
-
91
-
-
84871986003
-
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: The role of baseline inflammatory biomarkers
-
Raison CL, Rutherford RE, Woolwine BJ, Shuo C, Schettler P, Drake DF, Haroon E, Miller AH (2013) A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers. JAMA Psychiatry 70:31–41
-
(2013)
JAMA Psychiatry
, vol.70
, pp. 31-41
-
-
Raison, C.L.1
Rutherford, R.E.2
Woolwine, B.J.3
Shuo, C.4
Schettler, P.5
Drake, D.F.6
Haroon, E.7
Miller, A.H.8
-
92
-
-
84906329529
-
Targeting classical IL-6 signalling or IL-6 trans-signalling in depression?
-
Maes M, Anderson G, Kubera M, Berk M (2014) Targeting classical IL-6 signalling or IL-6 trans-signalling in depression? Expert Opin Ther Targets 18:495–512
-
(2014)
Expert Opin Ther Targets
, vol.18
, pp. 495-512
-
-
Maes, M.1
Erson, G.2
Kubera, M.3
Berk, M.4
-
93
-
-
84919402536
-
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality
-
Bay-Richter C, Linderholm KR, Lim CK, Samuelsson M, Traskman-Bendz L, Guillemin GJ, Erhardt S, Brundin L (2015) A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality. Brain Behav Immun 43:110–117
-
(2015)
Brain Behav Immun
, vol.43
, pp. 110-117
-
-
Bay-Richter, C.1
Linderholm, K.R.2
Lim, C.K.3
Samuelsson, M.4
Traskman-Bendz, L.5
Guillemin, G.J.6
Erhardt, S.7
Brundin, L.8
-
94
-
-
0033453996
-
Interleukin-1 beta production in dysthymia before and after pharmacotherapy
-
Anisman H, Ravindran AV, Griffiths J, Merali Z (1999) Interleukin-1 beta production in dysthymia before and after pharmacotherapy. Biol Psychiatry 46:1649–1655
-
(1999)
Biol Psychiatry
, vol.46
, pp. 1649-1655
-
-
Anisman, H.1
Ravindran, A.V.2
Griffiths, J.3
Merali, Z.4
-
95
-
-
52649171401
-
Symptoms of postpartum depression associated with elevated levels of interleukin-1 beta during the first month postpartum
-
Corwin EJ, Johnston N, Pugh L (2008) Symptoms of postpartum depression associated with elevated levels of interleukin-1 beta during the first month postpartum. Biol Res Nurs 10:128–133
-
(2008)
Biol Res Nurs
, vol.10
, pp. 128-133
-
-
Corwin, E.J.1
Johnston, N.2
Pugh, L.3
-
96
-
-
75149139478
-
Interleukin-1beta serum levels is increased in antidepressant-free elderly depressed patients
-
Diniz BS, Teixeira AL, Talib L, Gattaz WF, Forlenza OV (2010) Interleukin-1beta serum levels is increased in antidepressant-free elderly depressed patients. Am J Geriatr Psychiatry 18:172–176
-
(2010)
Am J Geriatr Psychiatry
, vol.18
, pp. 172-176
-
-
Diniz, B.S.1
Teixeira, A.L.2
Talib, L.3
Gattaz, W.F.4
Forlenza, O.V.5
-
97
-
-
68149110223
-
Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression
-
Koo JW, Duman RS (2009) Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Curr Opin Investig Drugs 10:664–671
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 664-671
-
-
Koo, J.W.1
Duman, R.S.2
-
99
-
-
38649092266
-
IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress
-
Koo JW, Duman RS (2008) IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc Natl Acad Sci U S A 105:751–756
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 751-756
-
-
Koo, J.W.1
Duman, R.S.2
-
100
-
-
84931266463
-
NLRP3 inflammasome mediates chronic mild stress-induced depression in mice via neuroinflammation
-
Zhang Y, Liu L, Liu YZ, Shen XL, Wu TY, Zhang T, Wang W, Wang YX, Jiang CL (2015) NLRP3 inflammasome mediates chronic mild stress-induced depression in mice via neuroinflammation. Int J Neuropsychopharmacol 18(8):pyv006
-
(2015)
Int J Neuropsychopharmacol
, vol.18
, Issue.8
-
-
Zhang, Y.1
Liu, L.2
Liu, Y.Z.3
Shen, X.L.4
Wu, T.Y.5
Zhang, T.6
Wang, W.7
Wang, Y.X.8
Jiang, C.L.9
-
101
-
-
0242456112
-
Interleukin 1 beta enhances conditioned fear memory in rats: Possible involvement of glucocorticoids
-
Song C, Phillips AG, Leonard B (2003) Interleukin 1 beta enhances conditioned fear memory in rats: possible involvement of glucocorticoids. Eur J Neurosci 18:1739–1743
-
(2003)
Eur J Neurosci
, vol.18
, pp. 1739-1743
-
-
Song, C.1
Phillips, A.G.2
Leonard, B.3
-
102
-
-
84955611614
-
Psychological stress activates the inflammasome via release of adenosine triphosphate and stimulation of the purinergic type 2X7 receptor
-
Iwata M, Ota KT, Li XY, Sakaue F, Li N, Dutheil S, Banasr M, Duric V, Yamanashi T, Kaneko K, Rasmussen K, Glasebrook A, Koester A, Song D, Jones KA, Zorn S, Smagin G, Duman RS (2016) Psychological stress activates the inflammasome via release of adenosine triphosphate and stimulation of the purinergic type 2X7 receptor. Biol Psychiatry 80:12–22
-
(2016)
Biol Psychiatry
, vol.80
, pp. 12-22
-
-
Iwata, M.1
Ota, K.T.2
Li, X.Y.3
Sakaue, F.4
Li, N.5
Dutheil, S.6
Banasr, M.7
Duric, V.8
Yamanashi, T.9
Kaneko, K.10
Rasmussen, K.11
Glasebrook, A.12
Koester, A.13
Song, D.14
Jones, K.A.15
Zorn, S.16
Smagin, G.17
Duman, R.S.18
-
103
-
-
84879260455
-
Neurochemical changes in the mouse hippocampus underlying the antidepressant effect of genetic deletion of P2X7 receptors
-
Csolle C, Baranyi M, Zsilla G, Kittel A, Goloncser F, Illes P, Papp E, Vizi ES, Sperlagh B (2013) Neurochemical changes in the mouse hippocampus underlying the antidepressant effect of genetic deletion of P2X7 receptors. PLoS One 8:e66547
-
(2013)
Plos One
, vol.8
-
-
Csolle, C.1
Baranyi, M.2
Zsilla, G.3
Kittel, A.4
Goloncser, F.5
Illes, P.6
Papp, E.7
Vizi, E.S.8
Sperlagh, B.9
-
104
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle M, Labasi J, Perregaux DG, Stam E, Petrushova N, Koller BH, Griffiths RJ, Gabel CA (2001) Altered cytokine production in mice lacking P2X(7) receptors. J Biol Chem 276:125–132
-
(2001)
J Biol Chem
, vol.276
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
105
-
-
84905216515
-
Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: Association with diseases, impact on receptor functions and potential use as diagnosis biomarkers
-
Caseley EA, Muench SP, Roger S, Mao HJ, Baldwin SA, Jiang LH (2014) Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers. Int J Mol Sci 15:13344–13371
-
(2014)
Int J Mol Sci
, vol.15
, pp. 13344-13371
-
-
Caseley, E.A.1
Muench, S.P.2
Roger, S.3
Mao, H.J.4
Baldwin, S.A.5
Jiang, L.H.6
-
106
-
-
84881489108
-
Insights into the molecular mechanisms underlying mammalian P2X7 receptor functions and contributions in diseases, revealed by structural modeling and single nucleotide polymorphisms
-
Jiang LH, Baldwin JM, Roger S, Baldwin SA (2013) Insights into the molecular mechanisms underlying mammalian P2X7 receptor functions and contributions in diseases, revealed by structural modeling and single nucleotide polymorphisms. Front Pharmacol 4:55
-
(2013)
Front Pharmacol
, vol.4
, pp. 55
-
-
Jiang, L.H.1
Baldwin, J.M.2
Roger, S.3
Baldwin, S.A.4
-
107
-
-
77955776526
-
Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion
-
Stokes L, Fuller SJ, Sluyter R, Skarratt KK, Gu BJ, Wiley JS (2010) Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion. FASEB J 24:2916–2927
-
(2010)
FASEB J
, vol.24
, pp. 2916-2927
-
-
Stokes, L.1
Fuller, S.J.2
Sluyter, R.3
Skarratt, K.K.4
Gu, B.J.5
Wiley, J.S.6
-
108
-
-
84895769853
-
Lack of association of P2RX7 gene rs2230912 polymorphism with mood disorders: A meta-analysis
-
Feng WP, Zhang B, Li W, Liu J (2014) Lack of association of P2RX7 gene rs2230912 polymorphism with mood disorders: a meta-analysis. PLoS One 9:e88575
-
(2014)
Plos One
, vol.9
-
-
Feng, W.P.1
Zhang, B.2
Li, W.3
Liu, J.4
-
109
-
-
45549084470
-
Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression
-
Goshen I, Kreisel T, Ben-Menachem-Zidon O, Licht T, Weidenfeld J, Ben-Hur T, Yirmiya R (2008) Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Mol Psychiatry 13:717–728
-
(2008)
Mol Psychiatry
, vol.13
, pp. 717-728
-
-
Goshen, I.1
Kreisel, T.2
Ben-Menachem-Zidon, O.3
Licht, T.4
Weidenfeld, J.5
Ben-Hur, T.6
Yirmiya, R.7
-
110
-
-
77950022786
-
Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
-
Rao JS, Harry GJ, Rapoport SI, Kim HW (2010) Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. Mol Psychiatry 15:384–392
-
(2010)
Mol Psychiatry
, vol.15
, pp. 384-392
-
-
Rao, J.S.1
Harry, G.J.2
Rapoport, S.I.3
Kim, H.W.4
-
111
-
-
84953359599
-
Role of P2X7 receptor in an animal model of mania induced by D-amphetamine
-
Gubert C, Fries GR, Pfaffenseller B, Ferrari P, Coutinho-Silva R, Morrone FB, Kapczinski F, Battastini AM (2016) Role of P2X7 receptor in an animal model of mania induced by D-amphetamine. Mol Neurobiol 53(1):611–620
-
(2016)
Mol Neurobiol
, vol.53
, Issue.1
, pp. 611-620
-
-
Gubert, C.1
Fries, G.R.2
Pfaffenseller, B.3
Ferrari, P.4
Coutinho-Silva, R.5
Morrone, F.B.6
Kapczinski, F.7
Battastini, A.M.8
-
112
-
-
84884546550
-
Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567
-
Bhattacharya A, Wang Q, Ao H, Shoblock JR, Lord B, Aluisio L, Fraser I, Nepomuceno D, Neff RA, Welty N, Lovenberg TW, Bonaventure P, Wickenden AD, Letavic MA (2013) Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567. Br J Pharmacol 170:624–640
-
(2013)
Br J Pharmacol
, vol.170
, pp. 624-640
-
-
Bhattacharya, A.1
Wang, Q.2
Ao, H.3
Shoblock, J.R.4
Lord, B.5
Aluisio, L.6
Fraser, I.7
Nepomuceno, D.8
Neff, R.A.9
Welty, N.10
Lovenberg, T.W.11
Bonaventure, P.12
Wickenden, A.D.13
Letavic, M.A.14
-
113
-
-
84908409069
-
Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432
-
Lord B, Aluisio L, Shoblock JR, Neff RA, Varlinskaya EI, Ceusters M, Lovenberg TW, Carruthers N, Bonaventure P, Letavic MA, Deak T, Drinkenburg W, Bhattacharya A (2014) Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432. J Pharmacol Exp Ther 351:628–641
-
(2014)
J Pharmacol Exp Ther
, vol.351
, pp. 628-641
-
-
Lord, B.1
Aluisio, L.2
Shoblock, J.R.3
Neff, R.A.4
Varlinskaya, E.I.5
Ceusters, M.6
Lovenberg, T.W.7
Carruthers, N.8
Bonaventure, P.9
Letavic, M.A.10
Deak, T.11
Drinkenburg, W.12
Bhattacharya, A.13
|