Unipolar depressive disorders have a common genotype

Journal of Affective Disorders

Volumn 117, Issue 1-2, 2009, Pages 30-41

  Edvardsen, Jack ^a   Torgersen, Svenn ^b,c   Røysamb, Espen ^b,d   Lygren, Sissel ^e   Skre, Ingunn ^f   Onstad, Sidsel ^g   Øien, Per Anders ^h  

^a Nordland Hospital Trust   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c Centre for Child and Adolescent Mental Health Eastern and Southern Norway   (Norway)

^d NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^e AKER UNIVERSITY HOSPITAL   (Norway)

^f UNIVERSITY OF TROMSØ   (Norway)

^g DIAKONHJEMMET HOSPITAL   (Norway)

^h Buskerud Hospital Trust   (Norway)

Author keywords

Heritability; Model fitting; Twins; Unipolar depression

Indexed keywords

ADULT; AGED; ARTICLE; ATYPICAL DEPRESSION; DISEASE PREDISPOSITION; DIZYGOTIC TWINS; DYSTHYMIA; ENVIRONMENTAL FACTOR; FEMALE; GENOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MONOZYGOTIC TWINS; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; DEPRESSIVE DISORDER; DEPRESSIVE DISORDER, MAJOR; DISEASES IN TWINS; DYSTHYMIC DISORDER; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; QUESTIONNAIRES; REGISTRIES; SEVERITY OF ILLNESS INDEX; SOCIAL ENVIRONMENT; TWINS; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC; YOUNG ADULT;

EID: 67650033123     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2008.12.004     Document Type: Article

References (64)

1. Akaike H. Factor analysis and AIC. Psychometrika 52 (1987) 317-332
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd edn. (1980), APA, Washington, DC
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd edn. (1987), APA, Wachington, DC revised
4. Angst J., Gamma A., Pezawas L., jdacic-Gross V., Eich D., Rossler W., and Altamura C. Parsing the clinical phenotype of depression: the need to integrate brief depressive episodes. Acta Psychiatr. Scand. 115 (2007) 221-228
5. Angst J., and Merikangas K. The depressive spectrum: diagnostic classification and course. J. Affect. Disord. 45 (1997) 31-39
6. Angst J., Sellaro R., and Merikangas K.R. Depressive spectrum diagnoses. Compr. Psychiatry 41 (2000) 39-47
7. Angst J., Sellaro R., Stassen H.H., and Gamma A. Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions. J. Affect. Disord. 84 (2005) 149-157
8. Bierut L.J., Heath A.C., Bucholz K.K., Dinwiddie S.H., Madden P.A., Statham D.J., Dunne M.P., and Martin N.G. Major depressive disorder in a community-based twin sample: are there different genetic and environmental contributions for men and women?. Arch. Gen. Psychiatry 56 (1999) 557-563
9. Cardno A.G., Marshall E.J., Coid B., Macdonald A.M., Ribchester T.R., Davies N.J., Venturi P., Jones L.A., Lewis S.W., Sham P.C., Gottesman I.I., Farmer A.E., McGuffin P., Reveley A.M., and Murray R.M. Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Arch. Gen. Psychiatry 56 (1999) 162-168
10. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., McClay J., Mill J., Martin J., Braithwaite A., and Poulton R. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301 (2003) 386-389
11. Coryell W., Endicott J., Maser J.D., Keller M.B., Leon A.C., and Akiskal H.S. Long-term stability of polarity distinctions in the affective disorders. Am. J. Psychiatry 152 (1995) 385-390
12. Cuijpers P., and Smit F. Subthreshold depression as a risk indicator for major depressive disorder: a systematic review of prospective studies. Acta Psychiatr. Scand. 109 (2004) 325-331
13. Donaldson S.K., Klein D.N., Riso L.P., and Schwartz J.E. Comorbidity between dysthymic and major depressive disorders: a family study analysis. J. Affect. Disord. 42 (1997) 103-111
14. Edvardsen J., Torgersen S., Roysamb E., Lygren S., Skre I., Onstad S., and Oien P.A. Heritability of bipolar spectrum disorders. Unity or heterogeneity?. J. Affect. Disord. 106 (2008) 229-240
15. Eley T.C., Sugden K., Corsico A., Gregory A.M., Sham P., McGuffin P., Plomin R., and Craig I.W. Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol. Psychiatry 9 (2004) 908-915
16. Fogel J., Eaton W.W., and Ford D.E. Minor depression as a predictor of the first onset of major depressive disorder over a 15-year follow-up. Acta Psychiatr. Scand. 113 (2006) 36-43
17. Foley D.L., Neale M.C., Gardner C.O., Pickles A., Prescott C.A., and Kendler K.S. Major depression and associated impairment: same or different genetic and environmental risk factors?. Am. J. Psychiatry 160 (2003) 2128-2133
18. Frodl T., Moller H.J., and Meisenzahl E. Neuroimaging genetics: new perspectives in research on major depression?. Acta Psychiatr. Scand. 118 (2008) 363-372
19. Fu Q., Heath A.C., Bucholz K.K., Nelson E., Goldberg J., Lyons M.J., True W.R., Jacob T., Tsuang M.T., and Eisen S.A. Shared genetic risk of major depression, alcohol dependence, and marijuana dependence: contribution of antisocial personality disorder in men. Arch. Gen. Psychiatry 59 (2002) 1125-1132
20. Goldberg J.F., Harrow M., and Whiteside J.E. Risk for bipolar illness in patients initially hospitalized for unipolar depression. Am. J. Psychiatry 158 (2001) 1265-1270
21. Holma K.M., Melartin T.K., Holma I.A., and Isometsa E.T. Predictors for switch from unipolar major depressive disorder to bipolar disorder type I or II: a 5-year prospective study. J. Clin. Psychiatry 69 (2008) 1267-1275
22. Judd L.L., Akiskal H.S., Maser J.D., Zeller P.J., Endicott J., Coryell W., Paulus M.P., Kunovac J.L., Leon A.C., Mueller T.I., Rice J.A., and Keller M.B. A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders. Arch. Gen. Psychiatry 55 (1998) 694-700
23. Karkowski L.M., and Kendler K.S. An examination of the genetic relationship between bipolar and unipolar illness in an epidemiological sample. Psychiatr. Genet. 7 (1997) 159-163
24. Keller M.B., Klein D.N., Hirschfeld R.M., Kocsis J.H., McCullough J.P., Miller I., First M.B., Holzer III C.P., Keitner G.I., and Marin D.B. Results of the DSM-IV mood disorders field trial. Am. J. Psychiatry 152 (1995) 843-849
25. Kendler K.S., and Gardner Jr. C.O. Boundaries of major depression: an evaluation of DSM-IV criteria. Am. J. Psychiatry 155 (1998) 172-177
26. Kendler K.S., Gardner C.O., Neale M.C., and Prescott C.A. Genetic risk factors for major depression in men and women: similar or different heritabilities and same or partly distinct genes?. Psychol. Med. 31 (2001) 605-616
27. Kendler K.S., Gatz M., Gardner C.O., and Pedersen N.L. A Swedish national twin study of lifetime major depression. Am. J. Psychiatry 163 (2006) 109-114
28. Kendler K.S., Kessler R.C., Walters E.E., MacLean C., Neale M.C., Heath A.C., and Eaves L.J. Stressful life events, genetic liability, and onset of an episode of major depression in women. Am. J. Psychiatry 152 (1995) 833-842
29. Kendler K.S., Kuhn J.W., Vittum J., Prescott C.A., and Riley B. The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch. Gen. Psychiatry 62 (2005) 529-535
30. Kendler K.S., Pedersen N., Johnson L., Neale M.C., and Mathe A.A. A pilot Swedish twin study of affective illness, including hospital- and population-ascertained subsamples. Arch. Gen. Psychiatry 50 (1993) 699-700
31. Kendler K.S., Pedersen N.L., Neale M.C., and Mathe A.A. A pilot Swedish twin study of affective illness including hospital- and population-ascertained subsamples: results of model fitting. Behav. Genet. 25 (1995) 217-232
32. Kendler K.S., and Prescott C.A. A population-based twin study of lifetime major depression in men and women. Arch. Gen. Psychiatry 56 (1999) 39-44
33. Kieseppä T., Partonen T., Haukka J., Kaprio J., and Lonnqvist J. High concordance of bipolar I disorder in a nationwide sample of twins. Am. J. Psychiatry 161 (2004) 1814-1821
34. Klein D.N., Shankman S.A., and Rose S. Ten-year prospective follow-up study of the naturalistic course of dysthymic disorder and double depression. Am. J. Psychiatry 163 (2006) 872-880
35. Klein D.N., Shankman S.A., and Rose S. Dysthymic disorder and double depression: prediction of 10-year course trajectories and outcomes. J. Psychiatr. Res. 42 (2008) 408-415
36. Lyons M.J., Eisen S.A., Goldberg J., True W., Lin N., Meyer J.M., Toomey R., Faraone S.V., Merla-Ramos M., and Tsuang M.T. A registry-based twin study of depression in men. Arch. Gen. Psychiatry 55 (1998) 468-472
37. McGuffin P., Katz R., and Rutherford J. Nature, nurture and depression: a twin study. Psychol. Med. 21 (1991) 329-335
38. McGuffin P., Katz R., Watkins S., and Rutherford J. A hospital-based twin register of the heritability of DSM-IV unipolar depression. Arch. Gen. Psychiatry 53 (1996) 129-136
39. McGuffin P., Rijsdijk F., Andrew M., Sham P., Katz R., and Cardno A. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch. Gen. Psychiatry 60 (2003) 497-502
40. Mondimore F.M. Unipolar depression/bipolar depression: connections and controversies. Int. Rev. Psychiatry 17 (2005) 39-47
41. Neale, M.C., Boker, S.M., Xie, G., Maes, H.H.M., 1999. Mx: Statistical Modeling, 5th ed. VCU Box, 900126, Richmond, VA23298, Department of Psychiatry. Ref Type: Computer Program.
42. Onstad S., Skre I., Torgersen S., and Kringlen E. Twin concordance for DSM-III-R schizophrenia. Acta Psychiatr. Scand. 83 (1991) 395-401
43. Oquendo M.A., Barrera A., Ellis S.P., Li S., Burke A.K., Grunebaum M., Endicott J., and Mann J.J. Instability of symptoms in recurrent major depression: a prospective study. Am. J. Psychiatry 161 (2004) 255-261
44. Orstavik R.E., Kendler K.S., Czajkowski N., Tambs K., and Reichborn-Kjennerud T. The relationship between depressive personality disorder and major depressive disorder: a population-based twin study. Am. J. Psychiatry 164 (2007) 1866-1872
45. Plomin R., DeFries J.C., McClearn G.E., and McGuffin P. Behavioral Genetics. 4th ed. (2001), Worth Publisher, New York
46. Rapaport M.H., Judd L.L., Schettler P.J., Yonkers K.A., Thase M.E., Kupfer D.J., Frank E., Plewes J.M., Tollefson G.D., and Rush A.J. A descriptive analysis of minor depression. Am. J. Psychiatry 159 (2002) 637-643
47. Rush A.J. The varied clinical presentations of major depressive disorder. J. Clin. Psychiatry 68 Suppl 8 (2007) 4-10
48. Sham P. Types of gene-environment interplay and their statistical properties. In: MacCabe J., O'Daly O., Murry R., McGuffin P., and Wright P. (Eds). Beyond Nature and Nurture in Psychiatry: Genes, Environment and Their Interplay (2006), Informa Healthcare, London 11-17
49. Shih R.A., Belmonte P.L., and Zandi P.P. A review of the evidence from family, twin and adoption studies for a genetic contribution to adult psychiatric disorders. Int. Rev. Psychiatry 16 (2004) 260-283
50. Skre I., Onstad S., Torgersen S., and Kringlen E. High interrater reliability for the Structured Clinical Interview for DSM-III-R Axis I (SCID-I). Acta Psychiatr. Scand. 84 (1991) 167-173
51. Skre I., Onstad S., Torgersen S., Lygren S., and Kringlen E. A twin study of DSM-III-R anxiety disorders. Acta Psychiatr. Scand. 88 (1993) 85-92
52. Skre I., Onstad S., Torgersen S., Lygren S., and Kringlen E. The heritability of common phobic fear: a twin study of a clinical sample. J. Anxiety Disord. 14 (2000) 549-562
53. Spitzer R.L., and Williams J.B.W. Structural Clinical Interview for DSM-III (SCID-I), Rev. Biometrical Research Department, New York State Psychiatric Institute, New York (1984)
54. SPSS Inc. SPSS. [12.0.1. Standard Version]. 11-11-2003. Chicago, Ilinois, SPSS Inc., 1989-2003. Ref Type: Computer Program.
55. Sullivan P.F., Neale M.C., and Kendler K.S. Genetic epidemiology of major depression: review and meta-analysis. Am. J. Psychiatry 157 (2000) 1552-1562
56. Torgersen S. The determination of twin zygosity by means of a mailed questionnaire. Acta Genet. Med. Gemellol. (Roma. ) 28 (1979) 225-236
57. Torgersen S. Genetic factors in moderately severe and mild affective disorders. Arch. Gen. Psychiatry 43 (1986) 222-226
58. Torgersen S., Lygren S., Oien P.A., Skre I., Onstad S., Edvardsen J., Tambs K., and Kringlen E. A twin study of personality disorders. Compr. Psychiatry 41 (2000) 416-425
59. Torgersen S., Skre I., Onstad S., Edvardsen J., and Kringlen E. The psychometric-genetic structure of DSM-III-R personality disorder criteria. J. Personality Disorder 7 (1993) 196-213
60. Uher R. The implications of gene-environment interactions in depression: will cause inform cure?. Mol. Psychiatry 13 (2008) 1070-1078
61. Uher R., and McGuffin P. The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol. Psychiatry 13 (2008) 131-146
62. Zubenko G.S., and Hughes III H.B. Effects of the G(-656)A variant on CREB1 promoter activity in a neuronal cell line: interactions with gonadal steroids and stress. Mol. Psychiatry 14 (2009) 390-397
63. Zubenko G.S., Hughes III H.B., Maher B.S., Stiffler J.S., Zubenko W.N., and Marazita M.L. Genetic linkage of region containing the CREB1 gene to depressive disorders in women from families with recurrent, early-onset, major depression. Am J Med Genet. 114 (2002) 980-987
64. Zubenko G.S., Hughes III H.B., Stiffler J.S., Brechbiel A., Zubenko W.N., Maher B.S., and Marazita M.L. Sequence variations in CREB1 cosegregate with depressive disorders in women. Mol. Psychiatry 8 (2003) 611-618