Ultrasmall superparamagnetic iron oxide nanoparticles acutely promote thrombosis and cardiac oxidative stress and DNA damage in mice

Particle and Fibre Toxicology

Volumn 13, Issue 1, 2016, Pages

  Nemmar, Abderrahim ^a   Beegam, Sumaya ^a   Yuvaraju, Priya ^a   Yasin, Javed ^a   Tariq, Saeed ^a   Attoub, Samir ^a   Ali, Badreldin H ^b  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b SULTAN QABOOS UNIVERSITY   (Oman)

Author keywords

Comet assay; Oxidative stress; Thrombosis; Toxicity; Ultrasmall superparamagnetic iron oxide nanoparticles

Indexed keywords

CREATINE KINASE MB; LACTATE DEHYDROGENASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TROPONIN I; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MAGNETITE NANOPARTICLE; MUTAGENIC AGENT; OXIDIZING AGENT; SERPINE1 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BAGG ALBINO MOUSE; CARDIOTOXICITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; EXHAUST GAS; FIBRINOLYSIS; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; THROMBOCYTE AGGREGATION; THROMBOGENICITY; THROMBOSIS; VENULE; AGONISTS; ANIMAL; BLOOD; CARDIAC MUSCLE; CHEMICALLY INDUCED; CHEMISTRY; COMET ASSAY; CORONARY ARTERY DISEASE; DOSE RESPONSE; DRUG EFFECTS; HEART; INTRAVENOUS DRUG ADMINISTRATION; MAGNETISM; METABOLISM; PARTICLE SIZE; TOXICITY TESTING;

ANIMALS; BIOMARKERS; COMET ASSAY; CORONARY DISEASE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; INJECTIONS, INTRAVENOUS; MAGNETIC PHENOMENA; MAGNETITE NANOPARTICLES; MICE, INBRED BALB C; MUTAGENS; MYOCARDIUM; OXIDANTS; OXIDATIVE STRESS; PARTIAL THROMBOPLASTIN TIME; PARTICLE SIZE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET AGGREGATION; PROTHROMBIN TIME; THROMBOSIS; TOXICITY TESTS, ACUTE;

EID: 85007443264     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/S12989-016-0132-X     Document Type: Article

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