The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Vermeij, Eline A ^a   Koenders, Marije I ^a   Bennink, Miranda B ^a   Crowe, Lindsey A ^b   Maurizi, Lionel ^c   Vallée, Jean Paul ^b   Hofmann, Heinrich ^c   Van Den Berg, Wim B ^a   Van Lent, Peter L E M ^a   Van De Loo, Fons A J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; POLYVINYL ALCOHOL; RNA; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; FERRIC ION; FERRIC OXIDE; MAGNETITE NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DRUG MEGADOSE; EXPERIMENTAL ARTHRITIS; FEMALE; GENE EXPRESSION; IN VIVO STUDY; LIVER; LOW DRUG DOSE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; SYNOVITIS; SYNOVIUM; UPREGULATION; ANIMAL; CHEMISTRY; GENETICS; IMMUNOLOGY; INTRAARTICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; PATHOLOGY;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CYTOKINES; FERRIC COMPOUNDS; INJECTIONS, INTRA-ARTICULAR; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICE; POLYVINYL ALCOHOL;

EID: 84949915324     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126687     Document Type: Article

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