Pulmonary exposure to diesel exhaust particles promotes cerebral microvessel thrombosis: Protective effect of a cysteine prodrug l-2-oxothiazolidine-4-carboxylic acid

Toxicology

Volumn 263, Issue 2-3, 2009, Pages 84-92

  Nemmar, Abderrahim ^a   Al Salam, Suhail ^a   Dhanasekaran, Subramanian ^a   Sudhadevi, Manjusha ^a   Ali, Badreldin H ^b  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b SULTAN QABOOS UNIVERSITY   (Oman)

Author keywords

Diesel exhaust particles; l 2 Oxothiazolidine 4 carboxylic acid; Lung inflammation; Particulate air pollution; Thrombosis

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; DIESEL FUEL; INTERLEUKIN 6; PROTEIN; SODIUM CHLORIDE; TROLOX C;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLEEDING TIME; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; ENVIRONMENTAL EXPOSURE; EXHAUST GAS; HISTOPATHOLOGY; LUNG LAVAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; OXIDATIVE STRESS; PARTICULATE MATTER; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESPIRATORY TRACT INFLAMMATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; VENULE;

AIR POLLUTANTS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; INTRACRANIAL THROMBOSIS; LUNG; MALE; MICE; MICE, INBRED STRAINS; MICROVESSELS; PARTICLE SIZE; PRODRUGS; PROTECTIVE AGENTS; PYRROLIDONECARBOXYLIC ACID; THIAZOLIDINES; VEHICLE EMISSIONS;

MUS;

EID: 68549105872     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.06.017     Document Type: Article

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