Exacerbation of thrombotic events by diesel exhaust particle in mouse model of hypertension

Toxicology

Volumn 285, Issue 1-2, 2011, Pages 39-45

  Nemmar, Abderrahim ^a   Zia, Shaheen ^a   Subramaniyan, Deepa ^a   Fahim, Mohamed A ^a   Ali, Badreldin H ^b  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b SULTAN QABOOS UNIVERSITY   (Oman)

Author keywords

Air pollution; Diesel exhaust particles; Hypertension; Thrombosis

Indexed keywords

ANGIOTENSIN II; INTERLEUKIN 6;

AIR POLLUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; EXHAUST GAS; HYPERTENSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE AGGREGATION; THROMBOSIS;

AIR POLLUTANTS; ANGIOTENSIN II; ANIMALS; BLOOD PLATELETS; BLOOD PRESSURE; CARBON DIOXIDE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTENSION; MALE; MICE; OXYGEN; PARTIAL THROMBOPLASTIN TIME; PARTICULATE MATTER; PLATELET AGGREGATION; PROTHROMBIN TIME; THROMBOSIS; VEHICLE EMISSIONS;

ANIMALIA; MUS;

EID: 79956192989     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.03.018     Document Type: Article

References (52)

1. Atkinson R.W., Anderson H.R., Sunyer J., Ayres J., Baccini M., Vonk J.M., Boumghar A., Forastiere F., Forsberg B., Touloumi G., Schwartz J., Katsouyanni K. Acute effects of particulate air pollution on respiratory admissions: results from APHEA 2 project. Air pollution and health: a European approach. Am. J. Respir. Crit. Care Med. 2001, 164:1860-1866.
2. Bateson T.F., Schwartz J. Who is sensitive to the effects of particulate air pollution on mortality? A case-crossover analysis of effect modifiers. Epidemiology 2004, 15:143-149.
3. Brook R.D., Franklin B., Cascio W., Hong Y.L., Howard G., Lipsett M., Luepker R., Mittleman M., Samet J., Smith S.C., Tager I. Air pollution and cardiovascular disease - a statement for healthcare professionals from the expert panel on population and prevention science of the American Heart Association. Circulation 2004, 109:2655-2671.
4. Brook R.D., Rajagopalan S., Pope C.A., Brook J.R., Bhatnagar A., Diez-Roux A.V., Holguin F., Hong Y.L., Luepker R.V., Mittleman M.A., Peters A., Siscovick D., Smith S.C., Whitsel L., Kaufman J.D. Particulate matter air pollution and cardiovascular disease an update to the scientific statement from the American Heart Association. Circulation 2010, 121:2331-2378.
5. Brook R.D., Urch B., Dvonch J.T., Bard R.L., Speck M., Keeler G., Morishita M., Marsik F.J., Kamal A.S., Kaciroti N., Harkema J., Corey P., Silverman F., Gold D.R., Wellenius G., Mittleman M.A., Rajagopalan S., Brook J.R. Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans. Hypertension 2009, 54:659-667.
6. Cheng T.J., Hwang J.S., Wang P.Y., Tsai C.F., Chen C.Y., Lin S.H., Chan C.C. Effects of concentrated ambient particles on heart rate and blood pressure in pulmonary hypertensive rats. Environ. Health Perspect. 2003, 111:147-150.
7. DeMeo D.L., Zanobetti A., Litonjua A.A., Coull B.A., Schwartz J., Gold D.R. Ambient air pollution and oxygen saturation. Am. J. Respir. Crit. Care Med. 2004, 170:383-387.
8. Driscoll K.E., Costa D.L., Hatch G., Henderson R., Oberdorster G., Salem H., Schlesinger R.B. Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations. Toxicol. Sci. 2000, 55:24-35.
9. El Sabban F., Radwan G.M. Influence of garlic compared to aspirin on induced photothrombosis in mouse pial microvessels, in vivo. Thromb. Res. 1997, 88:193-203.
10. El Sabban F.M., Ali B.H., Bashir A.K., Tanira M.O. The effect of gentamicin on acetylsalicylic acid-induced platelet antiaggregatory action in mouse pial arterioles. Life Sci. 1998, 62:1361-1369.
11. Gold D.R., Litonjua A., Schwartz J., Lovett E., Larson A., Nearing B., Allen G., Verrier M., Cherry R., Verrier R. Ambient pollution and heart rate variability. Circulation 2000, 101:1267-1273.
12. Helms M.N., Torres-Gonzalez E., Goodson P., Rojas M. Direct tracheal instillation of solutes into mouse lung. J. Vis. Exp. 2010.
13. Higashi Y., Sasaki S., Nakagawa K., Matsuura H., Oshima T., Chayama K. Endothelial function and oxidative stress in renovascular hypertension. N. Engl. J. Med. 2002, 346:1954-1962.
14. Kunzli N., Jerrett M., Mack W.J., Beckerman B., LaBree L., Gilliland F., Thomas D., Peters J., Hodis H.N. Ambient air pollution and atherosclerosis in Los Angeles. Environ. Health Perspect. 2005, 113:201-206.
15. Liao D., Creason J., Shy C., Williams R., Watts R., Zweidinger R. Daily variation of particulate air pollution and poor cardiac autonomic control in the elderly. Environ. Health Perspect. 1999, 107:521-525.
16. Mills N.L., Tornqvist H., Gonzalez M.C., Vink E., Robinson S.D., Soderberg S., Boon N.A., Donaldson K., Sandstrom T., Blomberg A., Newby D.E. Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N. Engl. J. Med. 2007, 357:1075-1082.
17. Mutlu G.M., Green D., Bellmeyer A., Baker C.M., Burgess Z., Rajamannan N., Christman J.W., Foiles N., Kamp D.W., Ghio A.J., Chandel N.S., Dean D.A., Sznajder J.I., Budinger G.R. Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J. Clin. Invest. 2007, 117:2952-2961.
18. Nemmar A., Al Maskari S., Ali B.H., Al Amri I.S. Cardiovascular and lung inflammatory effects induced by systemically administered diesel exhaust particles in rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 292:L664-L670.
19. Nemmar A., Al Salam S., Dhanasekaran S., Sudhadevi M., Ali B.H. Pulmonary exposure to diesel exhaust particles promotes cerebral microvessel thrombosis: protective effect of a cysteine prodrug l-2-oxothiazolidine-4-carboxylic acid. Toxicology 2009, 263:84-92.
20. Nemmar A., Al Salam S., Zia S., Dhanasekaran S., Shudadevi M., Ali B.H. Time-course effects of systemically administered diesel exhaust particles in rats. Toxicol. Lett. 2010, 194:58-65.
21. Nemmar A., Al Salam S., Zia S., Yasin J., Al H.I., Ali B.H. Diesel exhaust particles in the lung aggravate experimental acute renal failure. Toxicol. Sci. 2010, 113:267-277.
22. Nemmar A., Dhanasekaran S., Yasin J., Ba-Omar H., Fahim M.A., Kazzam E.E., Ali B.H. Evaluation of the direct systemic and cardiopulmonary effects of diesel particles in spontaneously hypertensive rats. Toxicology 2009, 262:50-56.
23. Nemmar A., Hoet P.H., Dinsdale D., Vermylen J., Hoylaerts M.F., Nemery B. Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 2003, 107:1202-1208.
24. Nemmar A., Hoet P.H., Vandervoort P., Dinsdale D., Nemery B., Hoylaerts M.F. Enhanced peripheral thrombogenicity after lung inflammation is mediated by platelet-leukocyte activation: role of P-selectin. J. Thromb. Haemost. 2007, 5:1217-1226.
25. Nemmar A., Hoet P.H.M., Vermylen J., Nemery B., Hoylaerts M.F. Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters. Circulation 2004, 110:1670-1677.
26. Nemmar A., Hoylaerts M., Hoet P.H., Vermylen J., Nemery B. Size effect of intratracheally instilled ultrafine particles on pulmonary inflammation and vascular thrombosis. Toxicol. Appl. Pharmacol. 2003, 186:38-45.
27. Nemmar A., Hoylaerts M.F., Hoet P.H.M., Dinsdale D., Smith T., Xu H., Vermylen J., Nemery B. Ultrafine particles affect experimental thrombosis in an in vivo hamster model. Am. J. Respir. Crit. Care Med. 2002, 166:998-1004.
28. Nemmar A., Inuwa I.M. Diesel exhaust particles in blood trigger systemic and pulmonary morphological alterations. Toxicol. Lett. 2008, 176:20-30.
29. Nemmar A., Melghit K., Ali B.H. The acute proinflammatory and prothrombotic effects of pulmonary exposure to rutile TiO2 nanorods in rats. Exp. Biol. Med. (Maywood) 2008, 233:610-619.
30. Nemmar A., Nemery B., Hoet P.H.M., Vermylen J., Hoylaerts M.F. Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters - role of histamine. Am. J. Respir. Crit. Care Med. 2003, 168:1366-1372.
31. O'Neill M.S., Veves A., Zanobetti A., Sarnat J.A., Gold D.R., Economides P.A., Horton E.S., Schwartz J. Diabetes enhances vulnerability to particulate air pollution-associated impairment in vascular reactivity and endothelial function. Circulation 2005, 111:2913-2920.
32. Packard R.R., Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin. Chem. 2008, 54:24-38.
33. Peters A., Dockery D.W., Muller J.E., Mittleman M.A. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 2001, 103:2810-2815.
34. Peters A., von Klot S., Heier M., Trentinaglia I., Hormann A., Wichmann H.E., Lowel H. Exposure to traffic and the onset of myocardial infarction. N. Engl. J. Med. 2004, 351:1721-1730.
35. Pope C.A., Burnett R.T., Thurston G.D., Thun M.J., Calle E.E., Krewski D., Godleski J.J. Cardiovascular mortality and long-term exposure to particulate air pollution-epidemiological evidence of general pathophysiological pathways of disease. Circulation 2004, 109:71-77.
36. Pope C.A., Schwartz J., Ransom M.R. Daily mortality and PM10 pollution in Utah Valley. Arch. Environ. Health 1992, 47:211-217.
37. Pope C.A., Verrier R.L., Lovett E.G., Larson A.C., Raizenne M.E., Kanner R.E., Schwartz J., Villegas G.M., Gold D.R., Dockery D.W. Heart rate variability associated with particulate air pollution. Am. Heart J. 1999, 138:890-899.
38. Rajagopalan S., Kurz S., Munzel T., Tarpey M., Freeman B.A., Griendling K.K., Harrison D.G. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest. 1996, 97:1916-1923.
39. Remkova A., Remko M. The role of renin-angiotensin system in prothrombotic state in essential hypertension. Physiol. Res. 2010, 59:13-23.
40. Ruckerl R., Greven S., Ljungman P., Aalto P., Antoniades C., Bellander T., Berglind N., Chrysohoou C., Forastiere F., Jacquemin B., von Klot S., Koenig W., Kuchenhoff H., Lanki T., Pekkanen J., Perucci C.A., Schneider A., Sunyer J., Peters A. Air pollution and inflammation (interleukin-6, C-reactive protein, fibrinogen) in myocardial infarction survivors. Environ. Health Perspect. 2007, 115:1072-1080.
41. Ruckerl R., Phipps R.P., Schneider A., Frampton M., Cyrys J., Oberdorster G., Wichmann H.E., Peters A. Ultrafine particles and platelet activation in patients with coronary heart disease-results from a prospective panel study. Part Fibre. Toxicol. 2007, 4:1.
42. Samet J.M., Dominici F., Curriero F.C., Coursac I., Zeger S.L. Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N. Engl. J. Med. 2000, 343:1742-1749.
43. Schwartz J. Air pollution and daily mortality: a review and meta analysis. Environ. Res. 1994, 64:36-52.
44. Silva V.M., Corson N., Elder A., Oberdorster G. The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (UFP). Toxicol. Sci. 2005, 85:983-989.
45. Sun Q., Yue P., Ying Z., Cardounel A.J., Brook R.D., Devlin R., Hwang J.S., Zweier J.L., Chen L.C., Rajagopalan S. Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK. Arterioscler. Thromb. Vasc. Biol. 2008, 28:1760-1766.
46. Tamagawa E., Bai N., Morimoto K., Gray C., Mui T., Yatera K., Zhang X., Xing L., Li Y., Laher I., Sin D.D., Man S.F., van Eeden S.F. Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 295:L79-L85.
47. Vermylen J., Nemmar A., Nemery B., Hoylaerts M.F. Ambient air pollution and acute myocardial infarction. J. Thromb. Haemost. 2005, 3:1955-1961.
48. Wichers L.B., Nolan J.P., Winsett D.W., Ledbetter A.D., Kodavanti U.P., Schladweiler M.C., Costa D.L., Watkinson W.P. Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part I: cardiovascular responses. Inhal. Toxicol 2004, 16:391-405.
49. Wordley J., Walters S., Ayres J.G. Short term variations in hospital admissions and mortality and particulate air pollution. Occup. Environ. Med. 1997, 54:108-116.
50. Yang P., Liu Y.F., Yang L., Wei Q., Zeng H. Mechanism and clinical significance of the prothrombotic state in patients with essential hypertension. Clin. Cardiol. 2010, 33:E81-E86.
51. Ying Z., Yue P., Xu X., Zhong M., Sun Q., Mikolaj M., Wang A., Brook R.D., Chen L.C., Rajagopalan S. Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase. Am. J. Physiol. Heart Circ. Physiol. 2009, 296:H1540-H1550.
52. Zappulla D. Environmental stress, erythrocyte dysfunctions, inflammation, and the metabolic syndrome: adaptations to CO2 increases?. J. Cardiometab. Syndr. 2008, 3:30-34.